Synthesis of (-)-epibatidine and its derivatives from chiral allene-1,3-dicarboxylate esters

Chemical and Pharmaceutical Bulletin

Volumn 54, Issue 3, 2006, Pages 399-402

  Kimura, Hiroyuki ^a   Fujiwara, Toshio ^a   Katoh, Takahiro ^a   Nishide, Kiyoharu ^a   Kajimoto, Tetsuya ^a   Node, Manabu ^a  

^a KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

( ) epibatidine; Chiral allene 1,3 dicarboxylate; Crystallization induced asymmetric transformation; Non opioidal anesthesia

Indexed keywords

DI(L)METHYLALLENE 1,3 DICARBOXYLATE; DICARBOXYLIC ACID DERIVATIVE; EPIBATIDINE; NICOTINIC RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; CHIRALITY; CRYSTALLIZATION; DRUG STRUCTURE; DRUG SYNTHESIS; NONHUMAN;

ALKADIENES; BICYCLO COMPOUNDS, HETEROCYCLIC; DICARBOXYLIC ACIDS; ESTERS; INDICATORS AND REAGENTS; MAGNETIC RESONANCE SPECTROSCOPY; NICOTINIC AGONISTS; PYRIDINES; RECEPTORS, NICOTINIC; SPECTROMETRY, MASS, FAST ATOM BOMBARDMENT; SPECTROPHOTOMETRY, INFRARED;

EID: 33645210971     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.54.399     Document Type: Article

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