Contribution of conserved polar glutamine, asparagine and threonine residues and glycosylation to agonist action at human P2X1 receptors for ATP

Journal of Neurochemistry

Volumn 96, Issue 3, 2006, Pages 843-852

  Roberts, Jonathan A ^a   Evans, Richard J ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

Glycosylation; Mutagenesis; P2X receptors; Structure function

Indexed keywords

2' O (4 BENZOYL) ATP; 3' O (4 BENZOYL) ATP; ASPARAGINE; DIADENOSINE PENTAPHOSPHATE; GLUTAMINE; PURINE P2X1 RECEPTOR; PURINERGIC RECEPTOR STIMULATING AGENT; SURAMIN; THREONINE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CHANNEL GATING; GENE MUTATION; GLYCOSYLATION; GOLGI COMPLEX; HUMAN; MUTAGENESIS; PRIORITY JOURNAL; RECEPTOR BINDING; STRUCTURE ACTIVITY RELATION;

ADENOSINE TRIPHOSPHATE; ANIMALS; ASPARAGINE; DOSE-RESPONSE RELATIONSHIP, RADIATION; ELECTRIC STIMULATION; GLUTAMINE; GLYCOSYLATION; HUMANS; MEMBRANE POTENTIALS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; OOCYTES; PATCH-CLAMP TECHNIQUES; POINT MUTATION; RECEPTORS, PURINERGIC P2; STRUCTURE-ACTIVITY RELATIONSHIP; THREONINE; XENOPUS;

EID: 33645099729     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2005.03593.x     Document Type: Article

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