Clinical trials in toxinology: More than a discussion between friends?

EMA - Emergency Medicine Australasia

Volumn 18, Issue 1, 2006, Pages 4-6

  Isbister, Geoffrey K ^a,b  

^a MENZIES SCHOOL OF HEALTH RESEARCH   (Australia)

^b Tropical Toxinology Unit   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

SNAKE VENOM ANTISERUM; SPIDER VENOM ANTISERUM;

CLINICAL TRIAL; DRUG COST; DRUG EFFICACY; DRUG SAFETY; EDITORIAL; HEALTH CARE QUALITY; HONEYBEE; HUMAN; PRIORITY JOURNAL; SKIN ULCER; SNAKEBITE; SPIDER BITE;

ANIMALS; ANTIVENINS; AUSTRALIA; BITES AND STINGS; CLINICAL TRIALS; EVIDENCE-BASED MEDICINE; HUMANS; TOXICOLOGY; TREATMENT OUTCOME; VENOMS;

EID: 33645090425     PISSN: 17426731     EISSN: 17426723     Source Type: Journal    
DOI: 10.1111/j.1742-6723.2006.00797.x     Document Type: Editorial

References (22)

1. Isbister GK Necrotic arachnidism: the mythology of a modern plague Lancet 2004 364 549 53
2. Isbister GK Gray MR White-tail spider bite: a prospective study of 130 definite bites by Lampona species MedJAust 2003 179 199 202
3. Isbister GK Whyte IM Suspected white-tail spider bite and necrotic ulcers InternMedJ 2004 34 38 44
4. Ellis RM Sprivulis PC Jelinek GA et al. A double-blind, randomized trial of intravenous versus intramuscular antivenom for Red-back spider envenoming EmergMedAustralas 2005 17 152 6
5. Bowra J Gillett M Morgan J Swinburn E Randomised crossover trial comparing hot showers and icepacks in the treatment of Physalia envenomation [Abstract]. EmergMed 2002 14 A22
6. Thomas CS Scott SA Galanis DJ Goto RS Box jellyfish (Carybdea alata) in Waikiki. The analgesic effect of sting-aid, Adolph's meat tenderizer and fresh water on their stings: a double-blinded, randomized, placebo-controlled clin trial Hawaii MedJ 2001 60 205 7 210
7. Balit CR Isbister GK Buckley NA Randomised controlled trial of topical aspirin in the treatment of bee and wasp stings JToxicolClinToxicol 2003 41 801 8
8. Caovilla JJ Barros EJ Efficacy of two different doses of antilonomic serum in the resolution of hemorrhagic syndrome resulting from envenoming by Lonomia obliqua caterpillars: a randomized controlled trial Toxicon 2004 43 811 18
9. Smalligan R Cole J Brito N et al. Crotaline snake bite in the Ecuadorian Amazon: randomised double blind comparative trial of three South American polyspecific antivenoms BMJ 2004 329 1129.
10. Dart RC Seifert SA Boyer LV A randomized multicenter trial of crotalinae polyvalent immune fab (ovine) antivenom for the treatment for crotaline snakebite in the United States ArchInternMed 2001 161 2030 6
11. Loten C Seymour J Jiang S Worsley D Healey P Isbister GK A Randomized Controlled Trial of Hot Water (45°C) Immersion versus Ice Packs for Physalia Stings Queenstown Australasian College for Emergency Medicine, Winter Symposium 2005
12. Gawarammana IB Kularatne SAM Dissanayake WP Kumarasiri RP Senanayake N Ariyasena H Parallel infusion of hydrocortisone +/- chlorpheniramine bolus injection to prevent acute adverse reactions to antivenom for snakebites - a randomised, double-blind, placebo-controlled study MedJAust 2004 180 20 3
13. Schnorf H Taurarii M Cundy T Ciguatera fish poisoning: a double-blind randomized trial of mannitol therapy Neurology 2002 58 873 80
14. Jorge MT Malaque C Ribeiro LA et al. Failure of chloramphenicol prophylaxis to reduce the frequency of abscess formation as a complication of envenoming by Bothrops snakes in Brazil: a double-blind randomized controlled trial TransRSocTropMedHyg 2004 98 529 34
15. Pardal PPD Souza SM Monteiro MRDD et al. Clinical trial of two antivenoms for the treatment of Bothrops and Lachesis bites in the north eastern Amazon region of Brazil TransRSocTropMedHyg 2004 98 28 42
16. Ariaratnam CA Sjostrom L Raziek Z et al. An open, randomized comparative trial of two antivenoms for the treatment of envenoming by Sri Lankan Russell's viper (Daboia russelii russelii) TransRSocTropMedHyg 2001 95 74 80
17. Paul V Pratibha S Prahlad KA Earali J Francis S Lewis F High-dose anti-snake venom versus low-dose anti-snake venom in the treatment of poisonous snake bites - a critical study JAssocPhysicians India 2004 52 14 17
18. Paul V Prahlad KA Earali J Francis S Lewis F Trial of heparin in viper bites JAssocPhysicians India 2003 51 163 6
19. Miao YN Chen MC Huang Z [Clinical observation on treatment of snake bite induced disseminated intravascular coagulation by qinwen baidu decoction.] Zhongguo Zhong Xi Yi Jie He Za Zhi 2003 23 590 2 (in Chinese).
20. White J Warrell D Eddleston M Currie BJ Whyte IM Isbister GK Clinical toxinology - where are we now? JToxicolClinToxicol 2003 41 263 76
21. Yeung JM Little M Murray LM Jelinek GA Daly FF Antivenom dosing in 35 patients with severe brown snake (Pseudonaja) envenoming in Western Australia over 10 years MedJAust 2004 181 703 5
22. Little M Is there a role for the use of pressure immobilisation bandages in the treatment of jellyfish envenomation in Australia? EmergMed(Fremantle) 2002 14 171 4