메뉴 건너뛰기




Volumn 5, Issue 1, 2006, Pages 19-28

A genetic screen for behavioral mutations that perturb dopaminergic homeostasis in mice

Author keywords

Dopamine; ENU; Locomotor; Mouse; Phenotype driven screen

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; GENE IDENTIFICATION; GENE MAPPING; GENE MUTATION; GENETIC ANALYSIS; GENETIC SCREENING; HOMEOSTASIS; LOCOMOTION; MALE; MOUSE; MUTAGENESIS; NEUROTRANSMISSION; NONHUMAN; PATHOPHYSIOLOGY; PHENOTYPE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SCHIZOPHRENIA; DOPAMINERGIC SYSTEM;

EID: 33645089673     PISSN: 16011848     EISSN: 1601183X     Source Type: Journal    
DOI: 10.1111/j.1601-183X.2005.00127.x     Document Type: Article
Times cited : (19)

References (33)
  • 2
    • 0036674495 scopus 로고    scopus 로고
    • Neuroscience of attention-deficit/hyperactivity disorder: The search for endophenotypes
    • Castellanos F.X. Tannock R. 2002 Neuroscience of attention-deficit/ hyperactivity disorder: the search for endophenotypes Nat Rev Neurosci 3 617 628
    • (2002) Nat Rev Neurosci , vol.3 , pp. 617-628
    • Castellanos, F.X.1    Tannock, R.2
  • 3
    • 0028151261 scopus 로고
    • Empirical threshold values for quantitative trait mapping
    • Churchill G.A. Doerge R.W. 1994 Empirical threshold values for quantitative trait mapping Genetics 138 963 971
    • (1994) Genetics , vol.138 , pp. 963-971
    • Churchill, G.A.1    Doerge, R.W.2
  • 4
    • 0036584950 scopus 로고    scopus 로고
    • Congenic mapping of alcohol and pentobarbital withdrawal liability loci to a <1 centimorgan interval of murine chromosome 4: Identification of Mpdz as a candidate gene
    • Fehr C. Shirley R.L. Belknap J.K. Crabbe J.C. Buck K.J. 2002 Congenic mapping of alcohol and pentobarbital withdrawal liability loci to a <1 centimorgan interval of murine chromosome 4: identification of Mpdz as a candidate gene J Neurosci 22 3730 3738
    • (2002) J Neurosci , vol.22 , pp. 3730-3738
    • Fehr, C.1    Shirley, R.L.2    Belknap, J.K.3    Crabbe, J.C.4    Buck, K.J.5
  • 7
    • 0030071106 scopus 로고    scopus 로고
    • Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter
    • Giros B. Jaber M. Jones S.R. Wightman R.M. Caron M.G. 1996 Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter Nature 379 606 612
    • (1996) Nature , vol.379 , pp. 606-612
    • Giros, B.1    Jaber, M.2    Jones, S.R.3    Wightman, R.M.4    Caron, M.G.5
  • 8
    • 0032961871 scopus 로고    scopus 로고
    • The flat-top gene is required for the expansion and regionalization of the telencephalic primordium
    • Hentges K. Thompson K. Peterson A. 1999 The flat-top gene is required for the expansion and regionalization of the telencephalic primordium Development 126 1601 1609
    • (1999) Development , vol.126 , pp. 1601-1609
    • Hentges, K.1    Thompson, K.2    Peterson, A.3
  • 9
    • 0022369586 scopus 로고
    • Dose-repetition increases the mutagenic effectiveness of N-ethyl-N-nitrosourea in mouse spermatogonia
    • Hitotsumachi S. Carpenter D.A. Russell W.L. 1985 Dose-repetition increases the mutagenic effectiveness of N-ethyl-N-nitrosourea in mouse spermatogonia Proc Natl Acad Sci USA 82 6619 6621
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 6619-6621
    • Hitotsumachi, S.1    Carpenter, D.A.2    Russell, W.L.3
  • 10
    • 0034425715 scopus 로고    scopus 로고
    • Genome-wide, large-scale production of mutant mice by ENU mutagenesis
    • Hrabe de Angelis M.H. Flaswinkel H. Fuchs H. et al. 2000 Genome-wide, large-scale production of mutant mice by ENU mutagenesis Nat Genet 25 444 447
    • (2000) Nat Genet , vol.25 , pp. 444-447
    • Hrabe De Angelis, M.H.1    Flaswinkel, H.2    Fuchs, H.3
  • 15
    • 0029869355 scopus 로고    scopus 로고
    • A screen for genes that function downstream of Ras1 during Drosophila eye development
    • Karim F.D. Chang H.C. Therrien M. Wassarman D.A. Laverty T. Rubin G.M. 1996 A screen for genes that function downstream of Ras1 during Drosophila eye development Genetics 143 315 329
    • (1996) Genetics , vol.143 , pp. 315-329
    • Karim, F.D.1    Chang, H.C.2    Therrien, M.3    Wassarman, D.A.4    Laverty, T.5    Rubin, G.M.6
  • 16
    • 0032560518 scopus 로고    scopus 로고
    • A phenotype-based screen for embryonic lethal mutations in the mouse
    • Kasarskis A. Manova K. Anderson K.V. 1998 A phenotype-based screen for embryonic lethal mutations in the mouse Proc Natl Acad Sci USA 95 7485 7490
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 7485-7490
    • Kasarskis, A.1    Manova, K.2    Anderson, K.V.3
  • 17
    • 0242583739 scopus 로고    scopus 로고
    • N-ethyl-N-nitrosourea mouse mutants in the dissection of behavioural and psychiatric disorders
    • Keays D.A. Nolan P.M. 2003 N-ethyl-N-nitrosourea mouse mutants in the dissection of behavioural and psychiatric disorders Eur J Pharmacol 480 205 217
    • (2003) Eur J Pharmacol , vol.480 , pp. 205-217
    • Keays, D.A.1    Nolan, P.M.2
  • 19
    • 0033730411 scopus 로고    scopus 로고
    • Identification and time dependence of quantitative trait loci for basal locomotor activity in the BXD recombinant inbred series and a B6D2 F2 intercross
    • Koyner J. Demarest K. McCaughran J. Jr. Cipp L. Hitzemann R. 2000 Identification and time dependence of quantitative trait loci for basal locomotor activity in the BXD recombinant inbred series and a B6D2 F2 intercross Behav Genet 30 159 170
    • (2000) Behav Genet , vol.30 , pp. 159-170
    • Koyner, J.1    Demarest, K.2    McCaughran Jr., J.3    Cipp, L.4    Hitzemann, R.5
  • 20
    • 0024508964 scopus 로고
    • Mapping mendelian factors underlying quantitative traits using RFLP linkage maps
    • Lander E.S. Botstein D. 1989 Mapping mendelian factors underlying quantitative traits using RFLP linkage maps Genetics 121 185 199
    • (1989) Genetics , vol.121 , pp. 185-199
    • Lander, E.S.1    Botstein, D.2
  • 21
    • 0036884733 scopus 로고    scopus 로고
    • Pathogenesis of Parkinson's disease: Dopamine, vesicles and alpha-synuclein
    • Lotharius J. Brundin P. 2002 Pathogenesis of Parkinson's disease: dopamine, vesicles and alpha-synuclein Nat Rev Neurosci 3 932 942
    • (2002) Nat Rev Neurosci , vol.3 , pp. 932-942
    • Lotharius, J.1    Brundin, P.2
  • 22
    • 0033860151 scopus 로고    scopus 로고
    • Implementation of a large-scale ENU mutagenesis program: Towards increasing the mouse mutant resource
    • Nolan P.M. Peters J. Vizor L. et al. 2000 Implementation of a large-scale ENU mutagenesis program: towards increasing the mouse mutant resource Mamm Genome 11 500 506
    • (2000) Mamm Genome , vol.11 , pp. 500-506
    • Nolan, P.M.1    Peters, J.2    Vizor, L.3
  • 25
    • 0037177552 scopus 로고    scopus 로고
    • Schizophrenia: Diverse approaches to a complex disease
    • Sawa A. Snyder S.H. 2002 Schizophrenia: diverse approaches to a complex disease Science 296 692 695
    • (2002) Science , vol.296 , pp. 692-695
    • Sawa, A.1    Snyder, S.H.2
  • 28
    • 0033231660 scopus 로고    scopus 로고
    • The dopamine hypothesis of reward: Past and current status
    • Spanagel R. Weiss F. 1999 The dopamine hypothesis of reward: past and current status Trends Neurosci 22 521 527
    • (1999) Trends Neurosci , vol.22 , pp. 521-527
    • Spanagel, R.1    Weiss, F.2
  • 29
    • 0033858624 scopus 로고    scopus 로고
    • Behavior and mutagenesis screens: The importance of baseline analysis of inbred strains
    • Tarantino L.M. Gould T.J. Druhan J.P. Bucan M. 2000 Behavior and mutagenesis screens: the importance of baseline analysis of inbred strains Mamm Genome 11 555 564
    • (2000) Mamm Genome , vol.11 , pp. 555-564
    • Tarantino, L.M.1    Gould, T.J.2    Druhan, J.P.3    Bucan, M.4
  • 31
    • 0038784461 scopus 로고    scopus 로고
    • A genetic screen for mouse mutations with defects in serotonin responsiveness
    • Weiss K.C. Kim D.Y. Pawson C.T. Cordes S.P. 2003 A genetic screen for mouse mutations with defects in serotonin responsiveness Brain Res Mol Brain Res 115 162 172
    • (2003) Brain Res Mol Brain Res , vol.115 , pp. 162-172
    • Weiss, K.C.1    Kim, D.Y.2    Pawson, C.T.3    Cordes, S.P.4
  • 32
    • 2642519680 scopus 로고    scopus 로고
    • Dopamine, learning and motivation
    • Wise R.A. 2004 Dopamine, learning and motivation Nat Rev Neurosci 5 483 494
    • (2004) Nat Rev Neurosci , vol.5 , pp. 483-494
    • Wise, R.A.1
  • 33
    • 19344362286 scopus 로고    scopus 로고
    • A focused and efficient genetic screening strategy in the mouse: Identification of mutations that disrupt cortical development
    • We thank Dr George Uhl for providing the DAT knockout mice. This research was supported by a NARSAD Young Investigator Award (D.J.S), grants from the NIH and the DOD (A.S.P) and funds from the state of California awarded to the University of California at San Francisco in support of research on alcoholism and drug dependence. We thank Rosanne Estrada, Eleanor Hawkins, Maiko Kikuchi, Olivia Lam and Szu-Min Han for assistance with mouse husbandry and screening.
    • Zarbalis K. May S.R. Shen Y. Ekker M. Rubenstein J.L. Peterson A.S. 2004 A focused and efficient genetic screening strategy in the mouse: identification of mutations that disrupt cortical development PLoS Biol 2 E219
    • (2004) PLoS Biol , vol.2 , pp. 219
    • Zarbalis, K.1    May, S.R.2    Shen, Y.3    Ekker, M.4    Rubenstein, J.L.5    Peterson, A.S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.