Raphanus sativus and its isothiocyanates inhibit vascular smooth muscle cells proliferation and induce G1 cell cycle arrest

International Immunopharmacology

Volumn 6, Issue 5, 2006, Pages 854-861

  Suh, Seok Jong ^a   Moon, Sung Kwon ^b   Kim, Cheorl Ho ^c  

^a Dongguk University   (South Korea)

^b Chungju National University   (South Korea)

^c Sungkyunkwan University   (South Korea)

Author keywords

4 (Methylthio) 3 butenyl isothiocyanate; Allyl isothiocayanate; Apoptosis; Benzyl isothiocyanate; Cell cycle arrest; DNA synthesis; Isothiocyanates; Phenethyl isothiocyanate; Raphanus sativus crude extract; VSMC

Indexed keywords

4 (METHYLTHIO) 3 BUTENYLISOTHIOCYANATE; ALLYL ISOTHIOCYANATE; BENZYL ISOTHIOCYANATE; CYCLIN D1; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN E; CYCLINE; DNA; HEXANE; ISOTHIOCYANIC ACID DERIVATIVE; PHENETHYL ISOTHIOCYANATE; PLANT EXTRACT; PROTEIN P21; PROTEIN P27; RAPHANUS SATIVUS EXTRACT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL CULTURE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL DEATH; CELL PROLIFERATION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA SYNTHESIS; DOWN REGULATION; DRUG EFFICACY; DRUG ISOLATION; DRUG MECHANISM; MALE; MEDICINAL PLANT; MITOSIS INHIBITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADISH; STATISTICAL SIGNIFICANCE; UPREGULATION; VASCULAR SMOOTH MUSCLE;

ANIMALS; AORTA; APOPTOSIS; CELL LINE; CELL PROLIFERATION; CYCLIN D1; CYCLIN E; CYCLIN-DEPENDENT KINASE 4; CYCLIN-DEPENDENT KINASE INHIBITOR P21; G1 PHASE; ISOTHIOCYANATES; MICE; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PLANT EXTRACTS; RAPHANUS;

EID: 33645021315     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2005.11.014     Document Type: Article

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