Assembling pieces of the cardiac puzzle; calreticulin and calcium-dependent pathways in cardiac development, health, and disease

Trends in Cardiovascular Medicine

Volumn 16, Issue 3, 2006, Pages 65-69

  Lynch, Jeffrey M ^a   Chilibeck, Kaari ^a   Qui, Yuanyuan ^a   Michalak, Marek ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); CALCINEURIN; CALCIUM ION; CALRETICULIN; MYOCARDIN; MYOCYTE ENHANCER FACTOR 2; MYOCYTE ENHANCER FACTOR 2C; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PROTEIN KINASE (CALCIUM,CALMODULIN); TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA 6; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTION FACTOR NFATC4; TRANSCRIPTION FACTOR NKX2.5; UNCLASSIFIED DRUG;

BRADYCARDIA; CALCIUM SIGNALING; CALCIUM TRANSPORT; COMPLETE HEART BLOCK; DOWN REGULATION; ENDOPLASMIC RETICULUM; GENE OVEREXPRESSION; GENE TARGETING; GENETIC TRANSCRIPTION; HEALTH STATUS; HEART DEVELOPMENT; HEART DISEASE; HEART FUNCTION; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; HUMAN; NONHUMAN; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN SYNTHESIS; REVIEW; SARCOPLASMIC RETICULUM; SUDDEN DEATH; T LYMPHOCYTE ACTIVATION;

ANIMALS; BRADYCARDIA; CALCINEURIN; CALCIUM; CALCIUM SIGNALING; CALRETICULIN; HEART; HEART BLOCK; HUMANS; MADS DOMAIN PROTEINS; MYOGENIC REGULATORY FACTORS; TRANSCRIPTION, GENETIC;

EID: 33645013860     PISSN: 10501738     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tcm.2006.01.004     Document Type: Review

References (35)

1. S Arnaudeau, M Frieden, and K Nakamura Calreticulin differentially modulates calcium uptake and release in the endoplasmic reticulum and mitochondria J Biol Chem 277 2002 46696 46705
2. K Baar Involvement of PPAR gamma co-activator-1, nuclear respiratory factors 1 and 2, and PPAR alpha in the adaptive response to endurance exercise Proc Nutr Soc 63 2004 269 273
3. EF Corbett, and M Michalak Calcium, a signaling molecule in the endoplasmic reticulum? Trends Biochem Sci 25 2000 307 311
4. MP Czubryt, J McAnally, GI Fishman, and EN Olson Regulation of peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PGC-1 alpha) and mitochondrial function by MEF2 and HDAC5 Proc Natl Acad Sci U S A 100 2003 1711 1716
5. L Ellgaard, and A Helenius Quality control in the endoplasmic reticulum Nat Rev Mol Cell Biol 4 2003 181 191
6. N Frey, and EN Olson Cardiac hypertrophy: the good, the bad, and the ugly Annu Rev Physiol 65 2003 45 79
7. L Guo, J Lynch, and K Nakamura COUP-TF1 antagonizes Nkx2.5-mediated activation of the calreticulin gene during cardiac development J Biol Chem 276 2001 2797 2801
8. L Guo, K Nakamura, and J Lynch Cardiac-specific expression of calcineurin reverses embryonic lethality in calreticulin-deficient mouse J Biol Chem 277 2002 50776 50779
9. C Handschin, and UA Meyer Induction of drug metabolism: the role of nuclear receptors Pharmacol Rev 55 2003 649 673
10. Y Ihara, K Kageyama, and T Kondo Overexpression of calreticulin sensitizes SERCA2a to oxidative stress Biochem Biophys Res Commun 329 2005 1343 1349
11. Y Ihara, Y Urata, S Goto, and T Kondo Role of calreticulin in the sensitivity of myocardiac H9c2 cells to oxidative stress caused by hydrogen peroxide Am J Physiol Cell Physiol 290 2006 C121 C208
12. 2+ spiking Mol Biol Cell 11 2000 1845 1858
13. K Kageyama, Y Ihara, and S Goto Overexpression of calreticulin modulates protein kinase B/Akt signaling to promote apoptosis during cardiac differentiation of cardiomyoblast H9c2 Cells J Biol Chem 277 2002 19255 19264
14. KH Lee, N Lee, and S Lim Calreticulin inhibits the MEK1,2-ERK1,2 pathway in alpha 1-adrenergic receptor/Gh-stimulated hypertrophy of neonatal rat cardiomyocytes J Steroid Biochem Mol Biol 84 2003 101 107
15. 2+ checkpoint in cardiac myofibrillogenesis J Cell Biol 158 2002 103 113
16. Q Lin, J Schwarz, C Bucana, and EN Olson Control of mouse cardiac morphogenesis and myogenesis by transcription factor MEF2C Science 276 1997 1404 1407
17. JV Linseman, and MR Bristow Drug therapy and heart failure prevention Circulation 107 2003 1234 1236
18. 3 receptors that may modulate excitation-contraction coupling in the heart Curr Biol 10 2000 939 942
19. 2+-dependent signaling cascade J Cell Biol 170 2005 37 47
20. TA McKinsey, and EN Olson Toward transcriptional therapies for the failing heart: chemical screens to modulate genes J Clin Invest 115 2005 538 546
21. TA McKinsey, CL Zhang, and EN Olson MEF2L: a calcium-dependent regulator of cell division, differentiation and death Trends Biochem Sci 27 2002 40 47
22. 2+ store: a view from the lumen Trends Biochem Sci 23 1998 10 14
23. A Mery, F Aimond, and C Menard Initiation of embryonic cardiac pacemaker activity by inositol 1,4,5-trisphosphate-dependent calcium signaling Mol Biol Cell 16 2005 2414 2423
24. N Mesaeli, K Nakamura, and E Zvaritch Calreticulin is essential for cardiac development J Cell Biol 144 1999 857 868
25. N Mesaeli, K Nakamura, M Opas, and M Michalak Endoplasmic reticulum in the heart, a forgotten organelle? Mol Cell Biochem 224 2001 1 6
26. M Michalak, EF Corbett, and N Mesaeli Calreticulin: one protein, one gene, many functions Biochem J 344 1999 281 292
27. 2+ signaling and calcium binding chaperones of the endoplasmic reticulum Cell Calcium 32 2002 269 278
28. K Nakamura, E Bossy-Wetzel, and K Burns Changes in endoplasmic reticulum luminal environment affect cell sensitivity to apoptosis J Cell Biol 150 2000 731 740
29. K Nakamura, M Robertson, and G Liu Complete heart block and sudden death in mouse over-expressing calreticulin J Clin Invest 107 2001 1245 1253
30. K Nakamura, A Zuppini, and S Arnaudeau Functional specialization of calreticulin domains J Cell Biol 154 2001 961 972
31. 2+ responses Science 280 1998 1763 1766
32. F Rusnak, and P Mertz Calcineurin: form and function Physiol Rev 80 2000 1483 1521
33. RC Scarpulla Transcriptional activators and coactivators in the nuclear control of mitochondrial function in mammalian cells Gene 286 2002 81 89
34. M Waser, N Mesaeli, C Spencer, and M Michalak Regulation of calreticulin gene expression by calcium J Cell Biol 138 1997 547 557
35. H Wu, FJ Naya, and TA McKinsey MEF2 responds to multiple calcium-regulated signals in the control of skeletal muscle fiber type EMBO J 19 2000 1963 1973