Computational modeling of a new fluorescent biosensor for caspase proteolytic activity improves dynamic range

IEEE Transactions on Nanobioscience

Volumn 5, Issue 1, 2006, Pages 41-45

  Chiang, Jason Jui Hsuan ^b,c   Truong, Kevin ^a,b  

^a IEEE   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c FPGA Computing Systems   (Canada)

Author keywords

Biosensor; Fluorescence resonance energy transfer (FRET); Imaging; Protein engineering

Indexed keywords

FLUORESCENCE RESONANCE ENERGY TRANSFER (FRET); PROTEASE; PROTEIN COMPLEXES; PROTEIN ENGINEERING;

COMPUTATION THEORY; CRYSTAL ATOMIC STRUCTURE; ENERGY TRANSFER; FLUORESCENCE; IMAGING TECHNIQUES; PATTERN RECOGNITION; PROTEINS;

BIOSENSORS;

CASPASE; CASPASE 3; PEPTIDE HYDROLASE;

ARTICLE; CHEMICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER AIDED DESIGN; COMPUTER SIMULATION; ENZYME ACTIVATION; EQUIPMENT; EQUIPMENT DESIGN; EVALUATION; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENETICS; INSTRUMENTATION; METHODOLOGY; PROTEIN ENGINEERING; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; STRUCTURE ACTIVITY RELATION;

CASPASE 3; CASPASES; COMPUTER SIMULATION; COMPUTER-AIDED DESIGN; ENZYME ACTIVATION; EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; FLUORESCENCE RESONANCE ENERGY TRANSFER; MODELS, CHEMICAL; MODELS, MOLECULAR; PEPTIDE HYDROLASES; PROTEIN ENGINEERING; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33644989490     PISSN: 15361241     EISSN: None     Source Type: Journal    
DOI: 10.1109/TNB.2005.864020     Document Type: Article

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