Altered subcellular distribution of IRS-1 and IRS-3 is associated with defective Akt activation and GLUT4 translocation in insulin-resistant old rat adipocytes

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1763, Issue 2, 2006, Pages 197-206

  Villar, Margarita ^a,c   Serrano, Rosario ^a   Gallardo, Nilda ^a   Carrascosa, José M ^b   Martinez, Carmen ^a   Andrés, Antonio ^a  

^a UNIVERSITY OF CASTILLA LA MANCHA   (Spain)

^b UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^c CENTRO DE BIOLOGÍA MOLECULAR SEVERO OCHOA   (Spain)

Author keywords

Adipocyte; Aging; Akt PKB; GLUT4; Insulin receptor substrate; Insulin resistance

Indexed keywords

GLUCOSE TRANSPORTER 4; HORMONE RECEPTOR STIMULATING AGENT; INSULIN RECEPTOR SUBSTRATE 1; IRS 3; PHOSPHOTYROSINE; PROTEIN KINASE B; UNCLASSIFIED DRUG;

ADIPOCYTE; ADIPOSE TISSUE; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL ISOLATION; CELL MEMBRANE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOSOL; MICROSOME; NONHUMAN; PRIORITY JOURNAL; RAT; WESTERN BLOTTING;

ADIPOCYTES; AGING; ANIMALS; BLOTTING, WESTERN; CELL MEMBRANE; CYTOSOL; DENSITOMETRY; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GLUCOSE TRANSPORTER TYPE 4; INSULIN; KINETICS; MALE; MICROSOMES; PHOSPHOPROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, WISTAR; SUBCELLULAR FRACTIONS;

ANIMALIA;

EID: 33644982433     PISSN: 01674889     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2005.12.005     Document Type: Article

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