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Volumn 27, Issue SUPPL., 2006, Pages

Therapeutic management of idiopathic pulmonary fibrosis: An evidence-based approach

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ANTIFIBROTIC AGENT; AZATHIOPRINE; BOSENTAN; CORTICOSTEROID; CYCLOPHOSPHAMIDE; ETANERCEPT; FG 3019; GAMMA1B INTERFERON; ILOPROST; IMATINIB; IMMUNOMODULATING AGENT; IMMUNOSUPPRESSIVE AGENT; MONOCLONAL ANTIBODY; PIRFENIDONE; PREDNISONE;

EID: 33644976115     PISSN: 02725231     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ccm.2005.08.004     Document Type: Review
Times cited : (11)

References (56)
  • 1
    • 0034133548 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: Diagnosis and treatment. International consensus statement
    • T.E. King Jr, U. Costabel, and J.-F. Cordieer Idiopathic pulmonary fibrosis: diagnosis and treatment. International consensus statement Am J Respir Crit Care Med 161 2000 646 664
    • (2000) Am J Respir Crit Care Med , vol.161 , pp. 646-664
    • King Jr., T.E.1    Costabel, U.2    Cordieer, J.-F.3
  • 2
    • 84921703046 scopus 로고    scopus 로고
    • Corticosteroids for idiopathic pulmonary fibrosis
    • John Wiley & Sons, Ltd Chichester (UK)
    • L. Richeldi, H.R. Davies, and G. Ferrara Corticosteroids for idiopathic pulmonary fibrosis The Cochrane Library, Issue 1 2004 John Wiley & Sons, Ltd Chichester (UK)
    • (2004) The Cochrane Library, Issue 1
    • Richeldi, L.1    Davies, H.R.2    Ferrara, G.3
  • 3
    • 0141836142 scopus 로고    scopus 로고
    • Immunomodulatory agents for idiopathic pulmonary fibrosis
    • John Wiley & Sons, Ltd Chichester (UK)
    • H.R. Davies, L. Richeldi, and E.H. Walters Immunomodulatory agents for idiopathic pulmonary fibrosis The Cochrane Library, Issue 1 2004 John Wiley & Sons, Ltd Chichester (UK)
    • (2004) The Cochrane Library, Issue 1
    • Davies, H.R.1    Richeldi, L.2    Walters, E.H.3
  • 4
    • 9344223323 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: New insights into pathogenesis
    • P.W. Noble, and R.J. Homer Idiopathic pulmonary fibrosis: new insights into pathogenesis Clin Chest Med 25 4 2004 749 758
    • (2004) Clin Chest Med , vol.25 , Issue.4 , pp. 749-758
    • Noble, P.W.1    Homer, R.J.2
  • 5
    • 1542411333 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis. Pathogenesis and therapeutic approaches
    • M. Selman, V.J. Thannickal, and A. Pardo Idiopathic pulmonary fibrosis. Pathogenesis and therapeutic approaches Drugs 64 4 2004 405 430
    • (2004) Drugs , vol.64 , Issue.4 , pp. 405-430
    • Selman, M.1    Thannickal, V.J.2    Pardo, A.3
  • 6
    • 0026741726 scopus 로고
    • Effect of γ-interferon on collagen synthesis by normal and fibrotic human lung fibroblasts
    • A.S. Narayanan, J. Whithey, and A. Souza Effect of γ-interferon on collagen synthesis by normal and fibrotic human lung fibroblasts Chest 101 5 1992 1326 1331
    • (1992) Chest , vol.101 , Issue.5 , pp. 1326-1331
    • Narayanan, A.S.1    Whithey, J.2    Souza, A.3
  • 7
    • 0024588790 scopus 로고
    • Effects of interferon-γ on expression of cell surface receptors for collagen and deposition of newly synthesized collagen by cultured human lung fibroblasts
    • J.G. Clark, T.F. Dedon, and E.A. Wayner Effects of interferon-γ on expression of cell surface receptors for collagen and deposition of newly synthesized collagen by cultured human lung fibroblasts J Clin Invest 83 5 1989 1505 1511
    • (1989) J Clin Invest , vol.83 , Issue.5 , pp. 1505-1511
    • Clark, J.G.1    Dedon, T.F.2    Wayner, E.A.3
  • 8
    • 0035085720 scopus 로고    scopus 로고
    • Molecular mechanisms of TGF-(beta) antagonism by interferon (gamma) and cyclosporine a in lung fibroblasts
    • O. Eickelberg, A. Pansky, and E. Koehler Molecular mechanisms of TGF-(beta) antagonism by interferon (gamma) and cyclosporine A in lung fibroblasts FASEB J 15 3 2001 797 806
    • (2001) FASEB J , vol.15 , Issue.3 , pp. 797-806
    • Eickelberg, O.1    Pansky, A.2    Koehler, E.3
  • 9
    • 0033452097 scopus 로고    scopus 로고
    • Interferon-gamma inhibits experimental renal fibrosis
    • S.D. Oldroyd, G.L. Thomas, and G. Gabbiani Interferon-gamma inhibits experimental renal fibrosis Kidney Int 56 6 1999 2116 2127
    • (1999) Kidney Int , vol.56 , Issue.6 , pp. 2116-2127
    • Oldroyd, S.D.1    Thomas, G.L.2    Gabbiani, G.3
  • 10
    • 0031738704 scopus 로고    scopus 로고
    • Immunomodulatory properties of interferon-gamma. An update
    • A. Billiau, H. Heremans, and K. Vermeire Immunomodulatory properties of interferon-gamma. An update Ann NY Acad Sci 856 1998 22 32
    • (1998) Ann NY Acad Sci , vol.856 , pp. 22-32
    • Billiau, A.1    Heremans, H.2    Vermeire, K.3
  • 11
    • 0035069871 scopus 로고    scopus 로고
    • Immunomodulatory approaches to augment phagocyte-mediated host defense for treatment of infectious diseases
    • W.C. Liles Immunomodulatory approaches to augment phagocyte-mediated host defense for treatment of infectious diseases Semin Respir Infect 16 1 2001 11 17
    • (2001) Semin Respir Infect , vol.16 , Issue.1 , pp. 11-17
    • Liles, W.C.1
  • 12
    • 0029124143 scopus 로고
    • Molecular mechanisms of antifibrotic effect of interferon gamma in bleomycin-mouse model of lung fibrosis: Downregulation of TGF-beta and procollagen I and III gene expression
    • G. Gurujeyalakshmi, and S.N. Giri Molecular mechanisms of antifibrotic effect of interferon gamma in bleomycin-mouse model of lung fibrosis: downregulation of TGF-beta and procollagen I and III gene expression Exp Lung Res 21 5 1995 791 808
    • (1995) Exp Lung Res , vol.21 , Issue.5 , pp. 791-808
    • Gurujeyalakshmi, G.1    Giri, S.N.2
  • 13
    • 0031833250 scopus 로고    scopus 로고
    • Pulmonary fibrosis: Cytokines in the balance
    • R.K. Coker, and G.J. Laurent Pulmonary fibrosis: cytokines in the balance Eur Respir J 11 6 1998 1218 1221
    • (1998) Eur Respir J , vol.11 , Issue.6 , pp. 1218-1221
    • Coker, R.K.1    Laurent, G.J.2
  • 14
    • 12744262853 scopus 로고    scopus 로고
    • CXCL11 attenuates bleomycin-induced pulmonary fibrosis via inhibition of vascular remodeling
    • M.D. Burdick, L.A. Murray, and M.P. Keane CXCL11 attenuates bleomycin-induced pulmonary fibrosis via inhibition of vascular remodeling Am J Respir Crit Care Med 171 2005 261 268
    • (2005) Am J Respir Crit Care Med , vol.171 , pp. 261-268
    • Burdick, M.D.1    Murray, L.A.2    Keane, M.P.3
  • 15
    • 0033592753 scopus 로고    scopus 로고
    • A preliminary study of long-term treatment with interferon gamma-1b and low-dose prednisolone in patients with idiopathic pulmonary fibrosis
    • R. Ziesche, E. Hofbauer, and K. Wittmann A preliminary study of long-term treatment with interferon gamma-1b and low-dose prednisolone in patients with idiopathic pulmonary fibrosis N Engl J Med 341 17 1999 1264 1269
    • (1999) N Engl J Med , vol.341 , Issue.17 , pp. 1264-1269
    • Ziesche, R.1    Hofbauer, E.2    Wittmann, K.3
  • 16
    • 0345824715 scopus 로고    scopus 로고
    • A placebo-controlled trial of interferon gamma-1b in patients with idiopathic pulmonary fibrosis
    • G. Raghu, K.K. Brown, and W.Z. Bradford A placebo-controlled trial of interferon gamma-1b in patients with idiopathic pulmonary fibrosis N Engl J Med 350 2 2004 125 133
    • (2004) N Engl J Med , vol.350 , Issue.2 , pp. 125-133
    • Raghu, G.1    Brown, K.K.2    Bradford, W.Z.3
  • 17
    • 13844316832 scopus 로고    scopus 로고
    • Analyses of efficacy end points in a controlled trial of interferon-γ1b for idiopathic pulmonary fibrosis
    • T.E. King Jr, S. Safrin, and K.M. Starko Analyses of efficacy end points in a controlled trial of interferon-γ1b for idiopathic pulmonary fibrosis Chest 127 1 2005 171 177
    • (2005) Chest , vol.127 , Issue.1 , pp. 171-177
    • King Jr., T.E.1    Safrin, S.2    Starko, K.M.3
  • 18
    • 3142768881 scopus 로고    scopus 로고
    • Idiopathic Pulmonary Fibrosis Biomarkers Study Group. Effects of interferon-γ 1b on biomarker expression in patients with idiopathic pulmonary fibrosis
    • R.M. Strieter, K.M. Starko, and R.I. Enelow Idiopathic Pulmonary Fibrosis Biomarkers Study Group. Effects of interferon-γ 1b on biomarker expression in patients with idiopathic pulmonary fibrosis Am J Respir Crit Care Med 170 2004 133 140
    • (2004) Am J Respir Crit Care Med , vol.170 , pp. 133-140
    • Strieter, R.M.1    Starko, K.M.2    Enelow, R.I.3
  • 19
    • 22244460509 scopus 로고    scopus 로고
    • Interferon gamma-1b therapy in IPF: A meta-analysis
    • E.K. Bajwa, N.T. Ayas, and M. Schulzer Interferon gamma-1b therapy in IPF: a meta-analysis Chest 128 2005 203 206
    • (2005) Chest , vol.128 , pp. 203-206
    • Bajwa, E.K.1    Ayas, N.T.2    Schulzer, M.3
  • 22
    • 0023263236 scopus 로고
    • Oxidant-mediated epithelial cell injury in idiopathic pulmonary fibrosis
    • A.M. Cantin, S.L. North, and G.A. Fells Oxidant-mediated epithelial cell injury in idiopathic pulmonary fibrosis J Clin Invest 79 6 1987 1665 1673
    • (1987) J Clin Invest , vol.79 , Issue.6 , pp. 1665-1673
    • Cantin, A.M.1    North, S.L.2    Fells, G.A.3
  • 23
    • 0025873171 scopus 로고
    • Pathogenetic significance of reactive oxygen species in diffuse fibrosing alveolitis
    • J. Behr, K. Maier, and F. Krombach Pathogenetic significance of reactive oxygen species in diffuse fibrosing alveolitis Am Rev Respir Dis 144 1 1991 146 150
    • (1991) Am Rev Respir Dis , vol.144 , Issue.1 , pp. 146-150
    • Behr, J.1    Maier, K.2    Krombach, F.3
  • 24
    • 0024578662 scopus 로고
    • Glutathione deficiency in the epithelial lining fluid of the lower respiratory tract in idiopathic pulmonary fibrosis
    • A.M. Cantin, R.C. Hubbard, and R.G. Crystal Glutathione deficiency in the epithelial lining fluid of the lower respiratory tract in idiopathic pulmonary fibrosis Am Rev Respir Dis 139 2 1989 370 372
    • (1989) Am Rev Respir Dis , vol.139 , Issue.2 , pp. 370-372
    • Cantin, A.M.1    Hubbard, R.C.2    Crystal, R.G.3
  • 25
    • 0031948449 scopus 로고    scopus 로고
    • Characterization of N-acetylcysteine and ambroxol in anti-oxidant therapy
    • A. Gillissen, and D. Nowak Characterization of N-acetylcysteine and ambroxol in anti-oxidant therapy Respir Med 92 4 1998 609 623
    • (1998) Respir Med , vol.92 , Issue.4 , pp. 609-623
    • Gillissen, A.1    Nowak, D.2
  • 26
    • 0031449645 scopus 로고    scopus 로고
    • Antioxidative and clinical effects of high-dose N-acetylcysteine in fibrosing alveolitis. Adjunctive therapy to maintenance immunosuppression
    • J. Behr, K. Maier, and B. Degenkolb Antioxidative and clinical effects of high-dose N-acetylcysteine in fibrosing alveolitis. Adjunctive therapy to maintenance immunosuppression Am J Respir Crit Care Med 156 6 1997 1897 1901
    • (1997) Am J Respir Crit Care Med , vol.156 , Issue.6 , pp. 1897-1901
    • Behr, J.1    Maier, K.2    Degenkolb, B.3
  • 27
    • 28144459814 scopus 로고    scopus 로고
    • High-dose acetylcysteine in idiopathic pulmonary fibrosis
    • M. Demedts, J. Behr, and R. Buhl High-dose acetylcysteine in idiopathic pulmonary fibrosis N Engl J Med 353 21 2005 2229 2242
    • (2005) N Engl J Med , vol.353 , Issue.21 , pp. 2229-2242
    • Demedts, M.1    Behr, J.2    Buhl, R.3
  • 28
    • 0035722931 scopus 로고    scopus 로고
    • Role of endothelin-1 in lung disease
    • K.A. Fagan, I.F. McMurtry, and D.M. Rodman Role of endothelin-1 in lung disease Respir Res 2 2 2001 90 101
    • (2001) Respir Res , vol.2 , Issue.2 , pp. 90-101
    • Fagan, K.A.1    McMurtry, I.F.2    Rodman, D.M.3
  • 29
    • 0030693699 scopus 로고    scopus 로고
    • Endothelin-1 induces bronchial myofibroblast differentiation
    • G. Sun, M.A. Stacey, and A. Bellini Endothelin-1 induces bronchial myofibroblast differentiation Peptides 18 9 1997 1449 1451
    • (1997) Peptides , vol.18 , Issue.9 , pp. 1449-1451
    • Sun, G.1    Stacey, M.A.2    Bellini, A.3
  • 30
    • 0033898202 scopus 로고    scopus 로고
    • Pulmonary fibrosis and chronic lung inflammation in ET-1 transgenic mice
    • B. Hocher, A. Schwarz, and K.A. Fagan Pulmonary fibrosis and chronic lung inflammation in ET-1 transgenic mice Am J Respir Cell Mol Biol 23 1 2000 19 26
    • (2000) Am J Respir Cell Mol Biol , vol.23 , Issue.1 , pp. 19-26
    • Hocher, B.1    Schwarz, A.2    Fagan, K.A.3
  • 31
    • 0030755489 scopus 로고    scopus 로고
    • Increased endothelin-1 in bleomycin-induced pulmonary fibrosis and the effect of an endothelin receptor antagonist
    • S.-H. Park, D. Saleh, and A. Giaid Increased endothelin-1 in bleomycin-induced pulmonary fibrosis and the effect of an endothelin receptor antagonist Am J Respir Crit Care Med 156 1997 600 608
    • (1997) Am J Respir Crit Care Med , vol.156 , pp. 600-608
    • Park, S.-H.1    Saleh, D.2    Giaid, A.3
  • 32
    • 0032056141 scopus 로고    scopus 로고
    • Effect of endothelin receptor antagonists (BQ-485, Ro 47-0203) on collagen deposition during the development of bleomycin-induced pulmonary fibrosis in rats
    • S.E. Mutsaers, R.P. Marshall, and N.R. Goldsack Effect of endothelin receptor antagonists (BQ-485, Ro 47-0203) on collagen deposition during the development of bleomycin-induced pulmonary fibrosis in rats Pulm Pharmacol Ther 11 2-3 1998 221 225
    • (1998) Pulm Pharmacol Ther , vol.11 , Issue.2-3 , pp. 221-225
    • Mutsaers, S.E.1    Marshall, R.P.2    Goldsack, N.R.3
  • 34
    • 0032842405 scopus 로고    scopus 로고
    • Effects of pirfenidone on transforming growth factor-β gene expression at the transcriptional level in bleomycin hamster model of lung fibrosis
    • S.N. Iyer, G. Gurujeyalakshmi, and S.N. Giri Effects of pirfenidone on transforming growth factor-β gene expression at the transcriptional level in bleomycin hamster model of lung fibrosis J Pharmacol Exp Ther 291 1 1999 367 373
    • (1999) J Pharmacol Exp Ther , vol.291 , Issue.1 , pp. 367-373
    • Iyer, S.N.1    Gurujeyalakshmi, G.2    Giri, S.N.3
  • 35
    • 0033923129 scopus 로고    scopus 로고
    • Anti-inflammatory effect of pirfenidone in the bleomycin-hamster model of lung inflammation
    • S.N. Iyer, D.M. Hyde, and S.N. Giri Anti-inflammatory effect of pirfenidone in the bleomycin-hamster model of lung inflammation Inflammation 24 5 2000 477 491
    • (2000) Inflammation , vol.24 , Issue.5 , pp. 477-491
    • Iyer, S.N.1    Hyde, D.M.2    Giri, S.N.3
  • 36
    • 0032926937 scopus 로고    scopus 로고
    • Treatment of idiopathic pulmonary fibrosis with a new antifibrotic agent, pirfenidone. Results of a prospective, open-label phase II study
    • G. Raghu, W.C. Johnson, and D. Lockhart Treatment of idiopathic pulmonary fibrosis with a new antifibrotic agent, pirfenidone. Results of a prospective, open-label phase II study Am J Respir Crit Care Med 159 1999 1061 1069
    • (1999) Am J Respir Crit Care Med , vol.159 , pp. 1061-1069
    • Raghu, G.1    Johnson, W.C.2    Lockhart, D.3
  • 37
    • 0036967820 scopus 로고    scopus 로고
    • Open-label compassionate use one year-treatment with pirfenidone to patients with chronic pulmonary fibrosis
    • S. Nagai, K. Hamada, and M. Shigematsu Open-label compassionate use one year-treatment with pirfenidone to patients with chronic pulmonary fibrosis Intern Med 41 12 2002 1118 1123
    • (2002) Intern Med , vol.41 , Issue.12 , pp. 1118-1123
    • Nagai, S.1    Hamada, K.2    Shigematsu, M.3
  • 38
    • 20944434994 scopus 로고    scopus 로고
    • Double-blind, placebo-controlled trial of pirfenidone in patients with idiopathic pulmonary fibrosis
    • A. Azuma, T. Nukiwa, and E. Tsuboi Double-blind, placebo-controlled trial of pirfenidone in patients with idiopathic pulmonary fibrosis Online Am J Respir Crit Care Med [serial online] January 21, 2005
    • (2005) Online Am J Respir Crit Care Med [Serial Online]
    • Azuma, A.1    Nukiwa, T.2    Tsuboi, E.3
  • 39
    • 0029114675 scopus 로고
    • Expression of a tumor necrosis factor-α transgene in murine lung causes lymphocytic and fibrosing alveolitis. a mouse model of progressive pulmonary fibrosis
    • Y. Miyazaki, K. Araki, and C. Vesin Expression of a tumor necrosis factor-α transgene in murine lung causes lymphocytic and fibrosing alveolitis. A mouse model of progressive pulmonary fibrosis J Clin Invest 96 1 1995 250 259
    • (1995) J Clin Invest , vol.96 , Issue.1 , pp. 250-259
    • Miyazaki, Y.1    Araki, K.2    Vesin, C.3
  • 40
    • 0346099102 scopus 로고    scopus 로고
    • Overexpression of tumor necrosis factor-α diminishes pulmonary fibrosis induced by bleomycin or transforming growth factor-β
    • M. Fujita, J.M. Shannon, and O. Morikawa Overexpression of tumor necrosis factor-α diminishes pulmonary fibrosis induced by bleomycin or transforming growth factor-β Am J Respir Cell Mol Biol 29 6 2003 669 676
    • (2003) Am J Respir Cell Mol Biol , vol.29 , Issue.6 , pp. 669-676
    • Fujita, M.1    Shannon, J.M.2    Morikawa, O.3
  • 41
    • 0033837130 scopus 로고    scopus 로고
    • Increased risk of fibrosing alveolitis associated with interleukin-1 receptor antagonist and tumor necrosis factor-α gene polymorphisms
    • M. Whyte, R. Hubbard, and R. Meliconi Increased risk of fibrosing alveolitis associated with interleukin-1 receptor antagonist and tumor necrosis factor-α gene polymorphisms Am J Respir Crit Care Med 162 2 2000 755 758
    • (2000) Am J Respir Crit Care Med , vol.162 , Issue.2 , pp. 755-758
    • Whyte, M.1    Hubbard, R.2    Meliconi, R.3
  • 42
    • 1542671910 scopus 로고    scopus 로고
    • An open label pilot study to determine the potential efficacy of TNFR:FC (Enbrel®, etanercept) in the treatment of usual interstitial pneumonia (UIP) [abstract]
    • A. Niden, M. Koss, and C.T. Boylen An open label pilot study to determine the potential efficacy of TNFR:FC (Enbrel®, etanercept) in the treatment of usual interstitial pneumonia (UIP) [abstract] Am J Respir Crit Care Med 165 2002 D27
    • (2002) Am J Respir Crit Care Med , vol.165 , pp. 27
    • Niden, A.1    Koss, M.2    Boylen, C.T.3
  • 44
    • 33644984283 scopus 로고    scopus 로고
    • The Coalition for Pulmonary Fibrosis
    • The Coalition for Pulmonary Fibrosis IPF research Available at: http://www.coalitionforpf.org/IPFResearch/default.asp Accessed March 15, 2005
    • IPF Research
  • 45
    • 0036090225 scopus 로고    scopus 로고
    • Treatment of chronic myelogenous leukemia with the tyrosine kinase inhibitor STI571 results in marked regression of bone marrow fibrosis
    • C. Beham-Schmid, U. Apfelbeck, and H. Sill Treatment of chronic myelogenous leukemia with the tyrosine kinase inhibitor STI571 results in marked regression of bone marrow fibrosis Blood 99 1 2002 381 383
    • (2002) Blood , vol.99 , Issue.1 , pp. 381-383
    • Beham-Schmid, C.1    Apfelbeck, U.2    Sill, H.3
  • 46
    • 20244364391 scopus 로고    scopus 로고
    • Inhibition of platelet-derived growth factor signaling attenuates pulmonary fibrosis
    • A. Abdollahi, M. Li, and G. Ping Inhibition of platelet-derived growth factor signaling attenuates pulmonary fibrosis J Exp Med 201 6 2005 925 935
    • (2005) J Exp Med , vol.201 , Issue.6 , pp. 925-935
    • Abdollahi, A.1    Li, M.2    Ping, G.3
  • 48
    • 15244339164 scopus 로고    scopus 로고
    • Imatinib mesylate inhibits the profibrogenic activity of TGF-β and prevents bleomycin-mediated lung fibrosis
    • C.E. Daniels, M.C. Wilkes, and M. Edens Imatinib mesylate inhibits the profibrogenic activity of TGF-β and prevents bleomycin-mediated lung fibrosis J Clin Invest 114 9 2004 1308 1316
    • (2004) J Clin Invest , vol.114 , Issue.9 , pp. 1308-1316
    • Daniels, C.E.1    Wilkes, M.C.2    Edens, M.3
  • 50
    • 33644971384 scopus 로고    scopus 로고
    • Pulmonary arterial hypertension (PAH) is common in patients with idiopathic pulmonary fibrosis referred for lung transplantation
    • D.A. Zisman, J.P. Lynch III, and R.M. Strieter Pulmonary arterial hypertension (PAH) is common in patients with idiopathic pulmonary fibrosis referred for lung transplantation Am J Respir Crit Care Med 2 2005 A123
    • (2005) Am J Respir Crit Care Med , vol.2 , pp. 123
    • Zisman, D.A.1    Lynch III, J.P.2    Strieter, R.M.3
  • 51
    • 33644972382 scopus 로고    scopus 로고
    • Prevalence of secondary pulmonary hypertension in patients with idiopathic pulmonary fibrosis
    • J. Gagermeier, J. Dauber, and K. Gibson Prevalence of secondary pulmonary hypertension in patients with idiopathic pulmonary fibrosis Am J Respir Crit Care Med 2 2005 A205
    • (2005) Am J Respir Crit Care Med , vol.2 , pp. 205
    • Gagermeier, J.1    Dauber, J.2    Gibson, K.3
  • 52
    • 27144547143 scopus 로고    scopus 로고
    • Pulmonary hypertension in patients with idiopathic pulmonary fibrosis
    • H.F. Nadrous, P.A. Pellikka, and M.J. Krowka Pulmonary hypertension in patients with idiopathic pulmonary fibrosis Chest 128 4 2005 2393 2399
    • (2005) Chest , vol.128 , Issue.4 , pp. 2393-2399
    • Nadrous, H.F.1    Pellikka, P.A.2    Krowka, M.J.3
  • 53
    • 0032810972 scopus 로고    scopus 로고
    • Inhaled prostacyclin and iloprost in severe pulmonary hypertension secondary to lung fibrosis
    • H. Olschewski, H.A. Ghofrani, and D. Walmrath Inhaled prostacyclin and iloprost in severe pulmonary hypertension secondary to lung fibrosis Am J Respir Crit Care Med 160 1999 600 607
    • (1999) Am J Respir Crit Care Med , vol.160 , pp. 600-607
    • Olschewski, H.1    Ghofrani, H.A.2    Walmrath, D.3
  • 54
    • 0037152092 scopus 로고    scopus 로고
    • Sildenafil for treatment of lung fibrosis and pulmonary hypertension: A randomised controlled trial
    • H.A. Ghofrani, R. Wiedemann, and F. Rose Sildenafil for treatment of lung fibrosis and pulmonary hypertension: a randomised controlled trial Lancet 360 2002 895 900
    • (2002) Lancet , vol.360 , pp. 895-900
    • Ghofrani, H.A.1    Wiedemann, R.2    Rose, F.3
  • 55
    • 0034883331 scopus 로고    scopus 로고
    • Type II alveolar epithelial cells and interstitial fibroblasts express connective tissue growth factor in IPF
    • L.H. Pan, K. Yamauchi, and M. Uzuki Type II alveolar epithelial cells and interstitial fibroblasts express connective tissue growth factor in IPF Eur Respir J 17 6 2001 1220 1227
    • (2001) Eur Respir J , vol.17 , Issue.6 , pp. 1220-1227
    • Pan, L.H.1    Yamauchi, K.2    Uzuki, M.3
  • 56
    • 33644516482 scopus 로고    scopus 로고
    • Safety and tolerability of human monoclonal antibody FG-3019, anti-connective tissue growth factor, in patients with idiopathic pulmonary fibrosis [abstract]
    • Y. Mageto, K. Flaherty, and K. Brown Safety and tolerability of human monoclonal antibody FG-3019, anti-connective tissue growth factor, in patients with idiopathic pulmonary fibrosis [abstract] Chest 126 4 Suppl 2004 S773
    • (2004) Chest , vol.126 , Issue.4 SUPPL. , pp. 773
    • Mageto, Y.1    Flaherty, K.2    Brown, K.3


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