Three-dimensional model of cytochrome P450 human aromatase

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 20, Issue 6, 2005, Pages 581-585

  Loge, Cedric ^a   Le Borgne, Marc ^a   Marchand, Pascal ^a   Robert, Jean Michel ^a   Le Baut, Guillaume ^a   Palzer, Martina ^b   Hartmann, Rolf W ^b  

^a Laboratoire de Pharmacochimie   (France)

^b SAARLAND UNIVERSITY   (Germany)

Author keywords

Active site; Aromatase; Breast cancer; CYP19; Homology modeling; Inhibitors; S fadrozole

Indexed keywords

10 THIIRANYLESTR 4 ENE 3,17 DIONE; AMINOGLUTETHIMIDE; ANASTROZOLE; ARGININE; AROMATASE; AROMATASE INHIBITOR; ASPARTIC ACID; CARBONYL DERIVATIVE; EXEMESTANE; FADROZOLE; FORMESTANE; HISTIDINE; LETROZOLE; LYSINE; NITRILE; STEROID; 10 THIIRANE 4 ESTRENE 3,17 DIONE; 10-THIIRANE-4-ESTRENE-3,17-DIONE; ENZYME INHIBITOR; ESTRANE DERIVATIVE;

AROMATIZATION; ARTICLE; CRYSTAL STRUCTURE; DRUG STRUCTURE; ENZYME ACTIVE SITE; ENZYME STRUCTURE; EUKARYOTE; HYDROGEN BOND; HYPOTHESIS; MODEL; MUTAGENESIS; PHARMACOPHORE; PRIORITY JOURNAL; AMINO ACID SEQUENCE; ANIMAL; BINDING COMPETITION; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; HUMAN; MOLECULAR GENETICS; RABBIT; SEQUENCE ALIGNMENT; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY;

EUKARYOTA; ORYCTOLAGUS CUNICULUS;

AMINO ACID SEQUENCE; ANIMALS; AROMATASE; BINDING SITES; BINDING, COMPETITIVE; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; ESTRENES; FADROZOLE; HUMANS; HYDROGEN BONDING; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; RABBITS; SEQUENCE ALIGNMENT; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33644972322     PISSN: 14756366     EISSN: 14756374     Source Type: Journal    
DOI: 10.1080/14756360500220574     Document Type: Article

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