Study of substrate specificity of human aromatase by site directed mutagenesis

European Journal of Biochemistry

Volumn 269, Issue 5, 2002, Pages 1393-1405

  Auvray, P ^a,c   Nativelle, C ^a   Bureau, R ^b   Dallemagne, P ^b   Seralini G E ^a   Sourdaine, P ^a  

^a UNIVERSITÉ DE CAEN   (France)

^b CENTRE D ETUDES ET DE RECHERCHE SUR LE MÉDICAMENT DE NORMANDIE   (France)

^c Oncodesign   (France)

Author keywords

Androgens; Aromatase; Inhibitors; Molecular modeling; Site directed mutagenesis

Indexed keywords

ANDROSTENEDIONE; AROMATASE; INDAN DERIVATIVE; NANDROLONE; TESTOSTERONE;

AROMATIZATION; ARTICLE; CATALYSIS; COMPUTER MODEL; CONTROLLED STUDY; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; HUMAN; MUTANT; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; AROMATASE; BINDING SITES; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; TESTOSTERONE;

BACTERIA (MICROORGANISMS);

EID: 0036118815     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1033.2002.02779.x     Document Type: Article

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