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Volumn 253, Issue 3, 2006, Pages 287-293

Predictors of long-term clinical response to interferon beta therapy in relapsing multiple sclerosis

Author keywords

Interferon beta; MRI; Neutralizing antibodies; Predictors

Indexed keywords

BETA1A INTERFERON; GADOLINIUM; INTERFERON BETA SERINE; NEUTRALIZING ANTIBODY;

EID: 33644964929     PISSN: 03405354     EISSN: 14321459     Source Type: Journal    
DOI: 10.1007/s00415-005-0979-5     Document Type: Article
Times cited : (106)

References (48)
  • 1
    • 0018942701 scopus 로고
    • Course and prognosis of multiple sclerosis assessed by the computerized data processing of 349 patients
    • Confavreux C, Aimard G, Devic M (1980) Course and prognosis of multiple sclerosis assessed by the computerized data processing of 349 patients. Brain 103:281-300
    • (1980) Brain , vol.103 , pp. 281-300
    • Confavreux, C.1    Aimard, G.2    Devic, M.3
  • 2
    • 0037379402 scopus 로고    scopus 로고
    • Early clinical predictors and progression of irreversible disability in multiple sclerosis: An amnesic process
    • Confavreux C, Vukusic S, Adeleine P (2003) Early clinical predictors and progression of irreversible disability in multiple sclerosis: an amnesic process. Brain 126:770-782
    • (2003) Brain , vol.126 , pp. 770-782
    • Confavreux, C.1    Vukusic, S.2    Adeleine, P.3
  • 3
    • 0024504359 scopus 로고
    • The natural history of multiple sclerosis: A geographically based study. I. Clinical course and disability
    • Weinshenker BG, Bass B, Rice GP, et al. (1989) The natural history of multiple sclerosis: a geographically based study. I. Clinical course and disability. Brain 112:133-146
    • (1989) Brain , vol.112 , pp. 133-146
    • Weinshenker, B.G.1    Bass, B.2    Rice, G.P.3
  • 4
    • 0024796845 scopus 로고
    • The natural history of multiple sclerosis: A geographically based study. II. Predictive value of the early clinical course
    • Weinshenker BG, Bass B, Rice GP, et al. (1989) The natural history of multiple sclerosis: a geographically based study. II. Predictive value of the early clinical course. Brain 112:1419-1428
    • (1989) Brain , vol.112 , pp. 1419-1428
    • Weinshenker, B.G.1    Bass, B.2    Rice, G.P.3
  • 5
    • 0027537209 scopus 로고
    • Prognostic factors in a multiple sclerosis incidence cohort with twenty-five years of follow-up
    • Runmarker B, Andersen O (1993) Prognostic factors in a multiple sclerosis incidence cohort with twenty-five years of follow-up. Brain 116:117-134
    • (1993) Brain , vol.116 , pp. 117-134
    • Runmarker, B.1    Andersen, O.2
  • 6
    • 0028934677 scopus 로고
    • Multivariate analysis of predictive factors of multiple sclerosis course with a validated method to assess clinical events
    • Trojano M, Avolio C, Manzari C, et al. (1995) Multivariate analysis of predictive factors of multiple sclerosis course with a validated method to assess clinical events. J Neurol Neurosurg Psychiatry 58:300-306
    • (1995) J Neurol Neurosurg Psychiatry , vol.58 , pp. 300-306
    • Trojano, M.1    Avolio, C.2    Manzari, C.3
  • 7
    • 0031750982 scopus 로고    scopus 로고
    • Survival and predictors of disability in Turkish MS patients
    • Turkish Multiple Sclerosis Study Group (TUMSSG)
    • Kantarci O, Siva A, Eraksoy M, et al. (1998) Survival and predictors of disability in Turkish MS patients. Turkish Multiple Sclerosis Study Group (TUMSSG). Neurology 51:765-772
    • (1998) Neurology , vol.51 , pp. 765-772
    • Kantarci, O.1    Siva, A.2    Eraksoy, M.3
  • 8
    • 0028359265 scopus 로고
    • Quantitative brain MRI lesion load predicts the course of clinically isolated syndromes suggestive of multiple sclerosis
    • Filippi M, Horsfield MA, Morrissey SP, et al. (1994) Quantitative brain MRI lesion load predicts the course of clinically isolated syndromes suggestive of multiple sclerosis. Neurology 44:635-641
    • (1994) Neurology , vol.44 , pp. 635-641
    • Filippi, M.1    Horsfield, M.A.2    Morrissey, S.P.3
  • 9
    • 0031882301 scopus 로고    scopus 로고
    • The prognostic value of brain MRI in clinically isolated syndromes of the CNS. A 10-year follow-up
    • O'Riordan JI, Thompson AJ, Kingsley DP, et al. (1998) The prognostic value of brain MRI in clinically isolated syndromes of the CNS. A 10-year follow-up. Brain 121:495-503
    • (1998) Brain , vol.121 , pp. 495-503
    • O'Riordan, J.I.1    Thompson, A.J.2    Kingsley, D.P.3
  • 11
    • 0030832846 scopus 로고    scopus 로고
    • Comparison of MRI criteria at first presentation to predict conversion to clinically definite multiple sclerosis
    • Barkhof F, Filippi M, Miller DH, et al. (1997) Comparison of MRI criteria at first presentation to predict conversion to clinically definite multiple sclerosis. Brain 120:2059-2069
    • (1997) Brain , vol.120 , pp. 2059-2069
    • Barkhof, F.1    Filippi, M.2    Miller, D.H.3
  • 12
    • 0033586376 scopus 로고    scopus 로고
    • Predictive value of gadolinium-enhanced magnetic resonance imaging for relapse rate and changes in disability or impairment in multiple sclerosis: A meta-analysis
    • Gadolinium MRI Meta-analysis Group
    • Kappos L, Moeri D, Radue EW, et al. (1999) Predictive value of gadolinium-enhanced magnetic resonance imaging for relapse rate and changes in disability or impairment in multiple sclerosis: a meta-analysis. Gadolinium MRI Meta-analysis Group. Lancet 353:964-969
    • (1999) Lancet , vol.353 , pp. 964-969
    • Kappos, L.1    Moeri, D.2    Radue, E.W.3
  • 13
    • 0037044262 scopus 로고    scopus 로고
    • MRI predictors of early conversion to clinically definite MS in the CHAMPS placebo group
    • CHAMPS Study Group (2002) MRI predictors of early conversion to clinically definite MS in the CHAMPS placebo group. Neurology 59:998-1005
    • (2002) Neurology , vol.59 , pp. 998-1005
  • 14
    • 0027418515 scopus 로고
    • Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. I. Clinical results of a multicenter, randomized, double-blind, placebo-controlled trial
    • The IFNB Multiple Sclerosis Study Group
    • The IFN beta Study Group (1993) Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. I. Clinical results of a multicenter, randomized, double-blind, placebo-controlled trial. The IFNB Multiple Sclerosis Study Group. Neurology 43:655-661
    • (1993) Neurology , vol.43 , pp. 655-661
  • 15
    • 0008678962 scopus 로고    scopus 로고
    • Intramuscular interferon beta-1a for disease progression in relapsing multiple sclerosis
    • The Multiple Sclerosis Collaborative Research Group (MSCRG)
    • Jacobs LD, Cookfair DL, Rudick RA, et al. (1996) Intramuscular interferon beta-1a for disease progression in relapsing multiple sclerosis. The Multiple Sclerosis Collaborative Research Group (MSCRG). Ann Neurol 39:285-294
    • (1996) Ann Neurol , vol.39 , pp. 285-294
    • Jacobs, L.D.1    Cookfair, D.L.2    Rudick, R.A.3
  • 16
    • 0345601517 scopus 로고    scopus 로고
    • Randomised double-blind placebo-controlled study of interferon beta-1a in relapsing/remitting multiple sclerosis
    • PRISMS (Prevention of Relapses and Disability by Interferon beta-1a Subcutaneously in Multiple Sclerosis) Study Group
    • Randomised double-blind placebo-controlled study of interferon beta-1a in relapsing/remitting multiple sclerosis (1998) PRISMS (Prevention of Relapses and Disability by Interferon beta-1a Subcutaneously in Multiple Sclerosis) Study Group. Lancet 352:1498-1504
    • (1998) Lancet , vol.352 , pp. 1498-1504
  • 17
    • 0021035886 scopus 로고
    • Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS)
    • Kurtzke JF (1983) Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology 33:1444-1452
    • (1983) Neurology , vol.33 , pp. 1444-1452
    • Kurtzke, J.F.1
  • 18
    • 0031736623 scopus 로고    scopus 로고
    • Determinants of Gd-enhanced MRI response to IFN-beta-1a treatment in relapsing-remitting multiple sclerosis
    • Koudriavtseva T, Pozzilli C, Fiorelli M, et al. (1998) Determinants of Gd-enhanced MRI response to IFN-beta-1a treatment in relapsing-remitting multiple sclerosis. Mult Scler 4:403-407
    • (1998) Mult Scler , vol.4 , pp. 403-407
    • Koudriavtseva, T.1    Pozzilli, C.2    Fiorelli, M.3
  • 19
    • 0037781808 scopus 로고    scopus 로고
    • Clinical characteristics of responders to interferon therapy for relapsing MS
    • Waubant E, Vukusic S, Gignoux L, et al. (2003) Clinical characteristics of responders to interferon therapy for relapsing MS. Neurology 61:184-189
    • (2003) Neurology , vol.61 , pp. 184-189
    • Waubant, E.1    Vukusic, S.2    Gignoux, L.3
  • 20
    • 0036007961 scopus 로고    scopus 로고
    • Interferon beta 1a (Avonex) treatment in multiple sclerosis: Similarity of effect on progression of disability in patients with mild and moderate disability
    • Vermersch P, de Seze J, Stojkovic T; G-SEP (Groupe Septentrional d'Etudes et de Recherches sur la SEP) (2002) Interferon beta 1a (Avonex) treatment in multiple sclerosis: similarity of effect on progression of disability in patients with mild and moderate disability. J Neurol 249:184-187
    • (2002) J Neurol , vol.249 , pp. 184-187
    • Vermersch, P.1    De Seze, J.2    Stojkovic, T.3
  • 21
    • 0005489101 scopus 로고    scopus 로고
    • Neutralizing antibodies during treatment of multiple sclerosis with interferon beta-1b: Experience during the first three years
    • The IFNB Multiple Sclerosis study group and the University of British Columbia MS/MRI analysis group (1996) Neutralizing antibodies during treatment of multiple sclerosis with interferon beta-1b: experience during the first three years. Neurology 47:889-894
    • (1996) Neurology , vol.47 , pp. 889-894
  • 22
    • 10744225329 scopus 로고    scopus 로고
    • Clinical importance of neutralising antibodies against interferon beta in patients with relapsing-remitting multiple sclerosis
    • Soelberg Sorensen P, Ross C, Clemmesen KM, et al. (2003) Clinical importance of neutralising antibodies against interferon beta in patients with relapsing-remitting multiple sclerosis. Lancet 362:1184-1191
    • (2003) Lancet , vol.362 , pp. 1184-1191
    • Soelberg Sorensen, P.1    Ross, C.2    Clemmesen, K.M.3
  • 23
    • 0029789322 scopus 로고    scopus 로고
    • Magnetic resonance imaging changes with recombinant human interferon-beta-1a: A short term study in relapsing-remitting multiple sclerosis
    • Pozzilli C, Bastianello S, Koudriavtseva T, et al. (1996) Magnetic resonance imaging changes with recombinant human interferon-beta-1a: a short term study in relapsing-remitting multiple sclerosis. J Neurol Neurosurg Psychiatry 61:251-258
    • (1996) J Neurol Neurosurg Psychiatry , vol.61 , pp. 251-258
    • Pozzilli, C.1    Bastianello, S.2    Koudriavtseva, T.3
  • 24
    • 0036835959 scopus 로고    scopus 로고
    • A 6-year clinical and MRI follow-up study of patients with relapsing-remitting multiple sclerosis treated with interferon-beta
    • Paolillo A, Pozzilli C, Giugni E, et al. (2002) A 6-year clinical and MRI follow-up study of patients with relapsing-remitting multiple sclerosis treated with interferon-beta. Eur J Neurol 9:645-655
    • (2002) Eur J Neurol , vol.9 , pp. 645-655
    • Paolillo, A.1    Pozzilli, C.2    Giugni, E.3
  • 25
    • 0142121383 scopus 로고    scopus 로고
    • Fate of neutralizing and binding antibodies to IFN beta in MS patients treated with IFN beta for 6 years
    • Bellomi F, Scagnolari C, Tomassini V, et al. (2003) Fate of neutralizing and binding antibodies to IFN beta in MS patients treated with IFN beta for 6 years. J Neurol Sci 215:3-8
    • (2003) J Neurol Sci , vol.215 , pp. 3-8
    • Bellomi, F.1    Scagnolari, C.2    Tomassini, V.3
  • 26
    • 0003997295 scopus 로고
    • Thirty-fifth report
    • Geneva: World Health Organization
    • WHO Expert Committee on Biological Standardisation (1985) Thirty-fifth report. WHO technical report series 725. Geneva: World Health Organization
    • (1985) WHO Technical Report Series 725
  • 27
    • 0022555790 scopus 로고
    • Quantitation of neutralization of interferon by antibody
    • Kawade Y (1986) Quantitation of neutralization of interferon by antibody. Methods Enzymol 119:558-573
    • (1986) Methods Enzymol , vol.119 , pp. 558-573
    • Kawade, Y.1
  • 28
    • 0034796419 scopus 로고    scopus 로고
    • The neutralization of interferon by antibody. II. Neutralizing antibody unitage and its relationship to bioassay sensitivity: The tenfold reduction unit
    • Grossberg SE, Kawade Y, Kohase M, Klein JP (2001) The neutralization of interferon by antibody. II. Neutralizing antibody unitage and its relationship to bioassay sensitivity: the tenfold reduction unit. J Interferon Cytokine Res 21:743-755
    • (2001) J Interferon Cytokine Res , vol.21 , pp. 743-755
    • Grossberg, S.E.1    Kawade, Y.2    Kohase, M.3    Klein, J.P.4
  • 29
    • 0029814538 scopus 로고    scopus 로고
    • Quantification of MRI lesion load in multiple sclerosis: A comparison of three computer-assisted techniques
    • Grimaud J, Lai M, Thorpe J, et al. (1996) Quantification of MRI lesion load in multiple sclerosis: a comparison of three computer-assisted techniques. Magn Reson Imaging 14: 495-505
    • (1996) Magn Reson Imaging , vol.14 , pp. 495-505
    • Grimaud, J.1    Lai, M.2    Thorpe, J.3
  • 30
    • 0031973909 scopus 로고    scopus 로고
    • The role of magnetic resonance techniques in understanding and managing multiple sclerosis
    • Miller DH, Grossman RI, Reingold SC, McFarland HF (1998) The role of magnetic resonance techniques in understanding and managing multiple sclerosis. Brain 121:3-24
    • (1998) Brain , vol.121 , pp. 3-24
    • Miller, D.H.1    Grossman, R.I.2    Reingold, S.C.3    McFarland, H.F.4
  • 31
    • 0036789860 scopus 로고    scopus 로고
    • Assessment of different treatment failure criteria in a cohort of relapsing-remitting multiple sclerosis patients treated with interferon beta: Implications for clinical trials
    • Rio J, Nos C, Tintore M, et al. (2002) Assessment of different treatment failure criteria in a cohort of relapsing-remitting multiple sclerosis patients treated with interferon beta: implications for clinical trials. Ann Neurol 52:400-406
    • (2002) Ann Neurol , vol.52 , pp. 400-406
    • Rio, J.1    Nos, C.2    Tintore, M.3
  • 32
    • 0034487603 scopus 로고    scopus 로고
    • Brain atrophy in relapsing multiple sclerosis: Relationship to relapses, EDSS, and treatment with interferon beta-1a
    • Rudick RA, Fisher E, Lee JC, Duda JT, Simon J (2000) Brain atrophy in relapsing multiple sclerosis: relationship to relapses, EDSS, and treatment with interferon beta-1a. Mult Scler 6:365-372
    • (2000) Mult Scler , vol.6 , pp. 365-372
    • Rudick, R.A.1    Fisher, E.2    Lee, J.C.3    Duda, J.T.4    Simon, J.5
  • 33
    • 0036189054 scopus 로고    scopus 로고
    • The role of MRI as surrogate outcome measure in multiple sclerosis
    • McFarland HF, Barkhof F, Antel J, Miller DH (2002) The role of MRI as surrogate outcome measure in multiple sclerosis. Mult Scler 8:40-51
    • (2002) Mult Scler , vol.8 , pp. 40-51
    • McFarland, H.F.1    Barkhof, F.2    Antel, J.3    Miller, D.H.4
  • 34
    • 0031844371 scopus 로고    scopus 로고
    • Histopathologic correlate of hypointense lesions on T1-weighted spin-echo MRI in multiple sclerosis
    • Van Walderveen MA, Kamphorst W, Scheltens P, et al. (1998) Histopathologic correlate of hypointense lesions on T1-weighted spin-echo MRI in multiple sclerosis. Neurology 50:1282-1288
    • (1998) Neurology , vol.50 , pp. 1282-1288
    • Van Walderveen, M.A.1    Kamphorst, W.2    Scheltens, P.3
  • 35
    • 0032724612 scopus 로고    scopus 로고
    • Axonal loss in multiple sclerosis lesions: Magnetic resonance imaging insights into substrates of disability
    • Van Waesberghe JH, Kamphorst W, De Groot CJ, et al. (1999) Axonal loss in multiple sclerosis lesions: magnetic resonance imaging insights into substrates of disability. Ann Neurol 46:747-754
    • (1999) Ann Neurol , vol.46 , pp. 747-754
    • Van Waesberghe, J.H.1    Kamphorst, W.2    De Groot, C.J.3
  • 36
    • 0029730733 scopus 로고    scopus 로고
    • Accumulation of hypointense lesions ("black holes") on T1 spin-echo MRI correlates with disease progression in multiple sclerosis
    • Truyen L, Van Waesberghe JH, Van Walderveen MA, et al. (1996) Accumulation of hypointense lesions ("black holes") on T1 spin-echo MRI correlates with disease progression in multiple sclerosis. Neurology 47:1469-1476
    • (1996) Neurology , vol.47 , pp. 1469-1476
    • Truyen, L.1    Van Waesberghe, J.H.2    Van Walderveen, M.A.3
  • 37
    • 0033852514 scopus 로고    scopus 로고
    • A longitudinal study of T1 hypointense lesions in relapsing MS: MSCRG trial of interferon beta-1a
    • Multiple Sclerosis Collaborative (Research Group)
    • Simon JH, Lull J, Jacobs LD, et al. (2000) A longitudinal study of T1 hypointense lesions in relapsing MS: MSCRG trial of interferon beta-1a. Multiple Sclerosis Collaborative (Research Group). Neurology 55:185-192
    • (2000) Neurology , vol.55 , pp. 185-192
    • Simon, J.H.1    Lull, J.2    Jacobs, L.D.3
  • 38
    • 0035849496 scopus 로고    scopus 로고
    • Randomized controlled trial of interferon beta-1a in secondary progressive MS: Clinical results
    • Secondary Progressive Efficacy Clinical Trial of Recombinant Interferon-beta-1a in MS (SPECTRIMS) Study Group (2001) Randomized controlled trial of interferon beta-1a in secondary progressive MS: clinical results. Neurology 56:1496-1504
    • (2001) Neurology , vol.56 , pp. 1496-1504
  • 39
    • 0035849494 scopus 로고    scopus 로고
    • Randomized controlled trial of interferon-beta-1a in secondary progressive MS: MRI results
    • Li DK, Zhao GJ, Paty DW, University of British Columbia MS/MRI Analysis Research Group, The SPECTRIMS Study Group (2001) Randomized controlled trial of interferon-beta-1a in secondary progressive MS: MRI results. Neurology 56:1505-1513
    • (2001) Neurology , vol.56 , pp. 1505-1513
    • Li, D.K.1    Zhao, G.J.2    Paty, D.W.3
  • 40
    • 0030005056 scopus 로고    scopus 로고
    • Effects of interferon-beta on steroid receptors, prostaglandins and enzymatic activities in human endometrial cancer
    • De Cicco Nardone F, Rossiello F, Iacopino F, et al. (1996) Effects of interferon-beta on steroid receptors, prostaglandins and enzymatic activities in human endometrial cancer. Anticancer Res 16:161-169
    • (1996) Anticancer Res , vol.16 , pp. 161-169
    • De Cicco Nardone, F.1    Rossiello, F.2    Iacopino, F.3
  • 41
    • 0032468321 scopus 로고    scopus 로고
    • Changes in cytokine production of breast cancer patients treated with interferons
    • Barak V, Kalickman I, Nisman B, et al. (1998) Changes in cytokine production of breast cancer patients treated with interferons. Cytokine 10:977-983
    • (1998) Cytokine , vol.10 , pp. 977-983
    • Barak, V.1    Kalickman, I.2    Nisman, B.3
  • 42
    • 0035171038 scopus 로고    scopus 로고
    • Hypointense lesions on T1-weighted spin-echo magnetic resonance imaging: Relation to clinical characteristics in subgroups of patients with multiple sclerosis
    • van Walderveen MA, Lycklama A, Nijeholt GJ, et al. (2001) Hypointense lesions on T1-weighted spin-echo magnetic resonance imaging: relation to clinical characteristics in subgroups of patients with multiple sclerosis. Arch Neurol 58(1):76-81
    • (2001) Arch Neurol , vol.58 , Issue.1 , pp. 76-81
    • Van Walderveen, M.A.1    Lycklama, A.2    Nijeholt, G.J.3
  • 43
    • 0037238049 scopus 로고    scopus 로고
    • Gender gap" in multiple sclerosis: Magnetic resonance imaging evidence
    • Pozzilli C, Tomassini V, Marinelli F, et al. (2003) "Gender gap" in multiple sclerosis: magnetic resonance imaging evidence. Eur J Neurol 10:95-97
    • (2003) Eur J Neurol , vol.10 , pp. 95-97
    • Pozzilli, C.1    Tomassini, V.2    Marinelli, F.3
  • 44
    • 1642277003 scopus 로고    scopus 로고
    • The clinical impact of interferon beta antibodies in relapsing-remitting MS
    • Perini P, Calabrese M, Biasi G, Gallo P (2004) The clinical impact of interferon beta antibodies in relapsing-remitting MS. J Neurol 251:305-309
    • (2004) J Neurol , vol.251 , pp. 305-309
    • Perini, P.1    Calabrese, M.2    Biasi, G.3    Gallo, P.4
  • 45
    • 2942592729 scopus 로고    scopus 로고
    • Neutralizing antibodies reduce the efficacy of beta IFN during treatment of multiple sclerosis
    • Malucchi S, Sala A, Gilli F, et al. (2004) Neutralizing antibodies reduce the efficacy of beta IFN during treatment of multiple sclerosis. Neurology 62:2031-2037
    • (2004) Neurology , vol.62 , pp. 2031-2037
    • Malucchi, S.1    Sala, A.2    Gilli, F.3
  • 46
    • 0037435532 scopus 로고    scopus 로고
    • Neutralizing antibodies during treatment of secondary progressive MS with interferon beta-1b
    • European Study Group in Interferon Beta-1b in Secondary Progressive MS
    • Polman C, Kappos L, White R, et al. (2003) European Study Group in Interferon Beta-1b in Secondary Progressive MS. Neutralizing antibodies during treatment of secondary progressive MS with interferon beta-1b. Neurology 60:37-43
    • (2003) Neurology , vol.60 , pp. 37-43
    • Polman, C.1    Kappos, L.2    White, R.3
  • 47
    • 0031891592 scopus 로고    scopus 로고
    • Correlations between monthly enhanced MRI lesion rate and changes in T2 lesion volume in multiple sclerosis
    • Molyneux PD, Filippi M, Barkhof F, et al. (1998) Correlations between monthly enhanced MRI lesion rate and changes in T2 lesion volume in multiple sclerosis. Ann Neurol 43:332-339
    • (1998) Ann Neurol , vol.43 , pp. 332-339
    • Molyneux, P.D.1    Filippi, M.2    Barkhof, F.3
  • 48
    • 4844223606 scopus 로고    scopus 로고
    • Defining interferon beta response status in multiple sclerosis patients
    • Rudick RA, Lee JC, Simon J, et al. (2004) Defining interferon beta response status in multiple sclerosis patients. Ann Neurol 56:548-555
    • (2004) Ann Neurol , vol.56 , pp. 548-555
    • Rudick, R.A.1    Lee, J.C.2    Simon, J.3


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