Anti-Plasmodium activity of imidazole-dioxolane compounds

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 9, 2006, Pages 2396-2406

  Vlahakis, Jason Z ^a   Kinobe, Robert T ^a   Nakatsu, Kanji ^a   Szarek, Walter A ^a   Crandall, Ian E ^b  

^a QUEEN S UNIVERSITY   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Antimalarial; Imidazole dioxolane compounds; Plasmodium falciparum

Indexed keywords

1 ACETOXY 2(1H IMIDAZOL 1 YL)BUTANE; 1,3 DIOXOLANE DERIVATIVE; 2 (2 PHENYLETHYL) 2 [(1H IMIDAZOL 1 YL)METHYL] 4 METHYL 1,3 DIOXOLANE; 2 [2 (4 CHLOROPHENYL)ETHYL] 2 [(1H IMIDAZOL 1 YL)METHYL] 4 [[(HYDROXYPHENYL)THIO]METHYL] 1,3 DIOXOLANE; 4 (4 CHLOROPHENYL) 2 (4 FLUOROBENZYLOXY) 1 (1H IMIDAZOL 1 YL)BUTANE; ANTIMALARIAL AGENT; CHLOROQUINE; HEME; IMIDAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHO CELL; CONTROLLED STUDY; DRUG ACTIVITY; DRUG BINDING; DRUG INHIBITION; DRUG MECHANISM; DRUG POTENTIATION; DRUG STRUCTURE; IN VITRO STUDY; NONHUMAN; PLASMODIUM FALCIPARUM;

ANIMALS; ANTIMALARIALS; CELLS, CULTURED; CHO CELLS; CRICETINAE; DIOXOLANES; HEME; IMIDAZOLES; MOLECULAR CONFORMATION; PARASITIC SENSITIVITY TESTS; PLASMODIUM FALCIPARUM; STEREOISOMERISM;

ANIMALIA; CRICETULUS GRISEUS; PLASMODIUM FALCIPARUM;

EID: 33644959834     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.01.122     Document Type: Article

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