Role of the C-terminal actin binding domain in BCR/ABL-mediated survival and drug resistance

British Journal of Haematology

Volumn 132, Issue 6, 2006, Pages 774-783

  Underhill Day, N ^a   Pierce, A ^a   Thompson, S E ^b   Xenaki, D ^b   Whetton, A D ^a   Owen Lynch, P J ^b  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b LANCASTER UNIVERSITY   (United Kingdom)

Author keywords

Actin binding domain; BCR ABL; Chronic myeloid leukaemia; Drug resistance; Progenitor cells

Indexed keywords

ACTIN BINDING PROTEIN; BCR ABL PROTEIN; CYTARABINE; DIACYLGLYCEROL; FIBRONECTIN; GROWTH FACTOR; HYDROXYUREA; PROTEIN TYROSINE KINASE;

APOPTOSIS; ARTICLE; BINDING SITE; CANCER MODEL; CANCER RESISTANCE; CARBOXY TERMINAL SEQUENCE; CELL PROLIFERATION; CELL SURVIVAL; CELLULAR DISTRIBUTION; CHRONIC LEUKEMIA; CHRONIC MYELOID LEUKEMIA; CONCENTRATION RESPONSE; DELETION MUTANT; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE DELETION; HEMATOPOIETIC STEM CELL; LEUKEMIA CELL LINE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SECOND MESSENGER; TEMPERATURE SENSITIVITY; WILD TYPE;

ACTINS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL DIFFERENTIATION; CELL DIVISION; CELL LINE, TUMOR; CLONING, MOLECULAR; CYTARABINE; DRUG RESISTANCE, NEOPLASM; FLUORESCENT ANTIBODY TECHNIQUE; FUSION PROTEINS, BCR-ABL; HUMANS; HYDROXYUREA; INTERLEUKIN-3; LEUKEMIA, MYELOID, CHRONIC; LIPIDS; MODELS, BIOLOGICAL; PROTEIN-TYROSINE KINASES; TEMPERATURE; TUMOR STEM CELLS;

EID: 33644930842     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2005.05949.x     Document Type: Article

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