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Volumn 15, Issue 3, 2005, Pages 197-205

Biological implications of filamin A-bound PEBP2β/CBFβ retention in the cytoplasm

Author keywords

Cytoskeleton; Human skeletal disorders; Inversion 16; Subcellular localization

Indexed keywords

ACTIN BINDING PROTEIN; CHIMERIC PROTEIN; CORE BINDING FACTOR; CORE BINDING FACTOR BETA; CYTOSKELETON PROTEIN; DNA BINDING PROTEIN; FILAMIN A; HETERODIMER; PROTEIN SUBUNIT; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR PEBP2BETA; TRANSCRIPTION FACTOR RUNX1; UNCLASSIFIED DRUG; CONTRACTILE PROTEIN; FILAMINS;

EID: 33644914523     PISSN: 10454403     EISSN: None     Source Type: Journal    
DOI: 10.1615/critreveukargeneexpr.v15.i3.20     Document Type: Review
Times cited : (9)

References (44)
  • 1
    • 0024294357 scopus 로고
    • Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-kappa B transcription factor
    • Baeuerle PA, Baltimore D. Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-kappa B transcription factor. Cell. 1988;53:615-23.
    • (1988) Cell , vol.53 , pp. 615-623
    • Baeuerle, P.A.1    Baltimore, D.2
  • 2
    • 0035877590 scopus 로고    scopus 로고
    • Regulation of nuclear localization during signaling
    • Cyert MS. Regulation of nuclear localization during signaling. J Biol Chem. 2001;276:20805-8.
    • (2001) J Biol Chem , vol.276 , pp. 20805-20808
    • Cyert, M.S.1
  • 3
    • 0038360785 scopus 로고    scopus 로고
    • Molecular mechanisms that regulate transcription factor localization suggest new targets for drug development
    • Lee S-H, Hannink M. Molecular mechanisms that regulate transcription factor localization suggest new targets for drug development. Adv Drug Delivery Rev. 2003;55:717-31.
    • (2003) Adv Drug Delivery Rev , vol.55 , pp. 717-731
    • Lee, S.-H.1    Hannink, M.2
  • 4
    • 2942574380 scopus 로고    scopus 로고
    • Coordinate regulation of cell growth and differentiation by TGF-β superfamily and Runx proteins
    • Miyazono K, Maeda S, Imamura T. Coordinate regulation of cell growth and differentiation by TGF-β superfamily and Runx proteins. Oncogene. 2004;23:4232-7.
    • (2004) Oncogene , vol.23 , pp. 4232-4237
    • Miyazono, K.1    Maeda, S.2    Imamura, T.3
  • 6
    • 0035947593 scopus 로고    scopus 로고
    • Filamin A associates with Smads and regulates transforming growth factor-β signaling
    • Sasaki A, Masuda Y, Ohta Y, Ikeda K, Watanabe K. Filamin A associates with Smads and regulates transforming growth factor-β signaling. J Biol Chem. 2001;276:17871-7.
    • (2001) J Biol Chem , vol.276 , pp. 17871-17877
    • Sasaki, A.1    Masuda, Y.2    Ohta, Y.3    Ikeda, K.4    Watanabe, K.5
  • 7
    • 0033768873 scopus 로고    scopus 로고
    • Androgen receptor nuclear translocation is facilitated by the f-actin cross-linking protein filamin
    • Ozanne DM, Brady ME, Cook S, Gaughan L, Neal DE, Robson CN. Androgen receptor nuclear translocation is facilitated by the f-actin cross-linking protein filamin. Mol Endocrinol. 2000;14:1618-26.
    • (2000) Mol Endocrinol , vol.14 , pp. 1618-1626
    • Ozanne, D.M.1    Brady, M.E.2    Cook, S.3    Gaughan, L.4    Neal, D.E.5    Robson, C.N.6
  • 8
    • 0033569711 scopus 로고    scopus 로고
    • The Ig fold of the core binding factor α Runt domain is a member of a family of structurally and functionally related Ig-fold DNA-binding domains
    • Berardi MJ, Sun C, Zehr M, Abildgaard F, Peng J, Speck NA, Bushweller JH. The Ig fold of the core binding factor α Runt domain is a member of a family of structurally and functionally related Ig-fold DNA-binding domains. Struct Fold Des. 1999;7:1247-56.
    • (1999) Struct Fold Des , vol.7 , pp. 1247-1256
    • Berardi, M.J.1    Sun, C.2    Zehr, M.3    Abildgaard, F.4    Peng, J.5    Speck, N.A.6    Bushweller, J.H.7
  • 9
    • 0032985363 scopus 로고    scopus 로고
    • Molecular insights into PEBP2/CBFβ-SMMHC associated acute leukemia revealed from the structure of PEBP2/CBFβ
    • Goger M, Gupta V, Kim WY, Shigesada K, Ito Y, Werner MH. Molecular insights into PEBP2/CBFβ-SMMHC associated acute leukemia revealed from the structure of PEBP2/CBFβ. Nat Struct Biol. 1999;6:620-3.
    • (1999) Nat Struct Biol , vol.6 , pp. 620-623
    • Goger, M.1    Gupta, V.2    Kim, W.Y.3    Shigesada, K.4    Ito, Y.5    Werner, M.H.6
  • 10
    • 0032983973 scopus 로고    scopus 로고
    • Solution structure of core binding factor beta and map of the CBF α binding site
    • Huang X, Peng JW, Speck NA, Bushweller JH. Solution structure of core binding factor beta and map of the CBF α binding site. Nat Struct Biol. 1999;6:624-7.
    • (1999) Nat Struct Biol , vol.6 , pp. 624-627
    • Huang, X.1    Peng, J.W.2    Speck, N.A.3    Bushweller, J.H.4
  • 12
    • 0034660045 scopus 로고    scopus 로고
    • Structural basis for the heterodimeric interaction between the acute leukaemia-associated transcription factors AML1 and CBFβ
    • Warren AJ, Bravo J, Williams RL, Rabbitts TH. Structural basis for the heterodimeric interaction between the acute leukaemia-associated transcription factors AML1 and CBFβ. EMBO J. 2000;19:3004-15.
    • (2000) EMBO J , vol.19 , pp. 3004-3015
    • Warren, A.J.1    Bravo, J.2    Williams, R.L.3    Rabbitts, T.H.4
  • 14
    • 0028839054 scopus 로고
    • Subcellular localization of the alpha and beta subunits of the acute myeloid leukemia-linked transcription factor PEBP2/CBF
    • Lu J, Maruyama M, Satake M, Bae SC, Ogawa E, Kagoshima H, Shigesada K, Ito Y. Subcellular localization of the alpha and beta subunits of the acute myeloid leukemia-linked transcription factor PEBP2/CBF. Mol Cell Biol. 1995;15:1651-61.
    • (1995) Mol Cell Biol , vol.15 , pp. 1651-1661
    • Lu, J.1    Maruyama, M.2    Satake, M.3    Bae, S.C.4    Ogawa, E.5    Kagoshima, H.6    Shigesada, K.7    Ito, Y.8
  • 17
    • 0031940065 scopus 로고    scopus 로고
    • Intrinsic transcriptional activation-inhibition domains of the polyomavirus enhancer binding protein 2/core binding factor α subunit revealed in the presence of the β subunit
    • Kanno T, Kanno Y, Chen LF, Ogawa E, Kim WY, Ito Y. Intrinsic transcriptional activation-inhibition domains of the polyomavirus enhancer binding protein 2/core binding factor α subunit revealed in the presence of the β subunit. Mol Cell Biol. 1998;18:2444-54.
    • (1998) Mol Cell Biol , vol.18 , pp. 2444-2454
    • Kanno, T.1    Kanno, Y.2    Chen, L.F.3    Ogawa, E.4    Kim, W.Y.5    Ito, Y.6
  • 18
    • 0030611853 scopus 로고    scopus 로고
    • The protooncogene product, PEBP2β/CBFβ, is mainly located in the cytoplasm and has an affinity with cytoskeletal structures
    • Tanaka Y, Watanabe T, Chiba N, Niki M, Kuroiwa Y, Nishihira T, Satomi S, Ito Y, Satake M. The protooncogene product, PEBP2β/CBFβ, is mainly located in the cytoplasm and has an affinity with cytoskeletal structures. Oncogene. 1997;15:677-83.
    • (1997) Oncogene , vol.15 , pp. 677-683
    • Tanaka, Y.1    Watanabe, T.2    Chiba, N.3    Niki, M.4    Kuroiwa, Y.5    Nishihira, T.6    Satomi, S.7    Ito, Y.8    Satake, M.9
  • 19
    • 0032031511 scopus 로고    scopus 로고
    • The AML1/ETO(MTG8) and AML1/Evi-1 leukemia-associated chimeric oncoproteins accumulate PEBP2β (CBFβ) in the nucleus more efficiently than wild-type AML1
    • Tanaka K, Tanaka T, Kurokawa M, Imai Y, Ogawa S, Mitani K, Yazaki Y, Hirai H. The AML1/ETO(MTG8) and AML1/Evi-1 leukemia-associated chimeric oncoproteins accumulate PEBP2β (CBFβ) in the nucleus more efficiently than wild-type AML1. Blood. 1998;91:1688-99.
    • (1998) Blood , vol.91 , pp. 1688-1699
    • Tanaka, K.1    Tanaka, T.2    Kurokawa, M.3    Imai, Y.4    Ogawa, S.5    Mitani, K.6    Yazaki, Y.7    Hirai, H.8
  • 20
    • 0031782323 scopus 로고    scopus 로고
    • The leukemic protein core binding factor β (CBFβ)-smooth-muscle myosin heavy chain sequesters CBFα2 into cytoskeletal filaments and aggregates
    • Adya N, Stacy T, Speck NA, Liu PP. The leukemic protein core binding factor β (CBFβ)-smooth-muscle myosin heavy chain sequesters CBFα2 into cytoskeletal filaments and aggregates. Mol Cell Biol. 1998;18:7432-43.
    • (1998) Mol Cell Biol , vol.18 , pp. 7432-7443
    • Adya, N.1    Stacy, T.2    Speck, N.A.3    Liu, P.P.4
  • 23
    • 7944237936 scopus 로고    scopus 로고
    • The many faces of filamin: A versatile molecular scaffold for cell motility and signaling
    • Feng Y, Walsh CA. The many faces of filamin: a versatile molecular scaffold for cell motility and signaling. Nat Cell Biol. 2004;6:1034-8.
    • (2004) Nat Cell Biol , vol.6 , pp. 1034-1038
    • Feng, Y.1    Walsh, C.A.2
  • 25
    • 0030993719 scopus 로고    scopus 로고
    • Differentiation dependent expression and distinct subcellular localization of the protooncogene product, PEBP2β/CBFβ, in muscle development
    • Chiba N, Watanabe T, Nomura S, Tanaka Y, Minowa M, Niki M, Kanamaru R, Satake M. Differentiation dependent expression and distinct subcellular localization of the protooncogene product, PEBP2β/CBFβ, in muscle development. Oncogene. 1997;14:2543-52.
    • (1997) Oncogene , vol.14 , pp. 2543-2552
    • Chiba, N.1    Watanabe, T.2    Nomura, S.3    Tanaka, Y.4    Minowa, M.5    Niki, M.6    Kanamaru, R.7    Satake, M.8
  • 26
    • 0018399979 scopus 로고
    • Identification of a high molecular weight actin-binding protein in skeletal muscle
    • Bechtel PJ. Identification of a high molecular weight actin-binding protein in skeletal muscle. J Biol Chem. 1979;254:1755-8.
    • (1979) J Biol Chem , vol.254 , pp. 1755-1758
    • Bechtel, P.J.1
  • 27
    • 0030061554 scopus 로고    scopus 로고
    • AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis
    • Okuda T, Deursen J, Hiebert SW, Grosveld G, Downing JR. AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis. Cell. 1996;84:321-30.
    • (1996) Cell , vol.84 , pp. 321-330
    • Okuda, T.1    Deursen, J.2    Hiebert, S.W.3    Grosveld, G.4    Downing, J.R.5
  • 29
    • 0029918597 scopus 로고    scopus 로고
    • Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis
    • U S A
    • Wang Q, Stacy T, Binder M, Marin-Padilla M, Sharpe AH, Speck NA. Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis. Proc Natl Acad Sci U S A. 1996;93:3444-9.
    • (1996) Proc Natl Acad Sci , vol.93 , pp. 3444-3449
    • Wang, Q.1    Stacy, T.2    Binder, M.3    Marin-Padilla, M.4    Sharpe, A.H.5    Speck, N.A.6
  • 31
    • 0030915268 scopus 로고    scopus 로고
    • Hematopoiesis in the fetal liver is impaired by targeted mutagenesis of a gene encoding a non-DNA binding subunit of the transcription factor, polyomavirus enhancer binding protein 2/core binding factor
    • U S A
    • Niki M, Okada H, Takano H, Kuno J, Tani K, Hibino H, Asano S, Ito Y, Satake M, Noda T. Hematopoiesis in the fetal liver is impaired by targeted mutagenesis of a gene encoding a non-DNA binding subunit of the transcription factor, polyomavirus enhancer binding protein 2/core binding factor. Proc Nad Acad Sci U S A. 1997;94:5697-5702.
    • (1997) Proc Nad Acad Sci , vol.94 , pp. 5697-5702
    • Niki, M.1    Okada, H.2    Takano, H.3    Kuno, J.4    Tani, K.5    Hibino, H.6    Asano, S.7    Ito, Y.8    Satake, M.9    Noda, T.10
  • 33
    • 0033697669 scopus 로고    scopus 로고
    • Haploinsufficiency of AML1 affects the temporal and spatial generation of hematopoietic stem cells in the mouse embryo
    • Cai Z, de Bruijn M, Ma X, Dortland B, Luteijn T, Downing RJ, Dzierzak E. Haploinsufficiency of AML1 affects the temporal and spatial generation of hematopoietic stem cells in the mouse embryo. Immunity. 2000;13:423-31.
    • (2000) Immunity , vol.13 , pp. 423-431
    • Cai, Z.1    De Bruijn, M.2    Ma, X.3    Dortland, B.4    Luteijn, T.5    Downing, R.J.6    Dzierzak, E.7
  • 34
    • 0034176176 scopus 로고    scopus 로고
    • The AML1 transcription factor functions to develop and maintain hematogenic precursor cells in the embryonic aorta-gonad-mesonephros region
    • Mukouyama Y, Chiba N, Hara T, Okada H, Ito Y, Kanamaru R, Miyajima A, Satake M, Watanabe T. The AML1 transcription factor functions to develop and maintain hematogenic precursor cells in the embryonic aorta-gonad-mesonephros region. Dev Biol. 2000;220:27-36.
    • (2000) Dev Biol , vol.220 , pp. 27-36
    • Mukouyama, Y.1    Chiba, N.2    Hara, T.3    Okada, H.4    Ito, Y.5    Kanamaru, R.6    Miyajima, A.7    Satake, M.8    Watanabe, T.9
  • 37
    • 1842426730 scopus 로고    scopus 로고
    • Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment
    • NcBeath R, Pirone DM, Nelson CM, Bhadriraju K, Chen CS. Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment. Dev Cell. 2004;6:483-95.
    • (2004) Dev Cell , vol.6 , pp. 483-495
    • NcBeath, R.1    Pirone, D.M.2    Nelson, C.M.3    Bhadriraju, K.4    Chen, C.S.5
  • 41
    • 0033623914 scopus 로고    scopus 로고
    • The PEBP2β/CBFβ-SMMHC chimeric protein is localized both in the cell membrane and nuclear subfractions of leukemic cells carrying chromosomal inversion 16
    • Kanto S, Chiba N, Tanaka Y, Fujita S, Endo M, Kamada N, Yoshikawa K, Fukuzaki A, Orikasa S, Watanabe T, Satake M. The PEBP2β/CBFβ-SMMHC chimeric protein is localized both in the cell membrane and nuclear subfractions of leukemic cells carrying chromosomal inversion 16. Leukemia. 2000;14:1253-9.
    • (2000) Leukemia , vol.14 , pp. 1253-1259
    • Kanto, S.1    Chiba, N.2    Tanaka, Y.3    Fujita, S.4    Endo, M.5    Kamada, N.6    Yoshikawa, K.7    Fukuzaki, A.8    Orikasa, S.9    Watanabe, T.10    Satake, M.11
  • 42
    • 2942602706 scopus 로고    scopus 로고
    • Mechanism of leukemogenesis by the inv(16) chimeric gene CBFB/PEBP2B-MYH11
    • Shigesada K, van de Sluis B, Liu PP. Mechanism of leukemogenesis by the inv(16) chimeric gene CBFB/PEBP2B-MYH11. Oncogene. 2004;23:4297-307.
    • (2004) Oncogene , vol.23 , pp. 4297-4307
    • Shigesada, K.1    Van De Sluis, B.2    Liu, P.P.3
  • 44
    • 0025363536 scopus 로고
    • Cancer cell structure: Actin changes in tumour cells - Possible mechanisms for malignant tumour formation
    • Holme TC. Cancer cell structure: actin changes in tumour cells - possible mechanisms for malignant tumour formation. Eur J Surg Oncol. 1990;16:161-9.
    • (1990) Eur J Surg Oncol , vol.16 , pp. 161-169
    • Holme, T.C.1


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