Oral immunization of mice using transgenic tomato fruit expressing VP1 protein from enterovirus 71

Vaccine

Volumn 24, Issue 15, 2006, Pages 2944-2951

  Chen, Hsuan Fu ^a,b   Chang, Meng Huei ^a   Chiang, Bor Luen ^b   Jeng, Shih Tong ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Enterovirus 71; Oral immunization; Transgenic tomato fruit

Indexed keywords

IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; PROTEIN VP1; UNCLASSIFIED DRUG; VIRUS VACCINE; VP1 VACCINE;

ANIMAL EXPERIMENT; ARTICLE; CELL PROLIFERATION; CELL STIMULATION; CELLULAR IMMUNITY; DRUG ACTIVITY; DRUG MECHANISM; DRUG SYNTHESIS; ENDOPLASMIC RETICULUM; ENTEROVIRUS 71; FEMALE; GENE EXPRESSION; GENETIC TRANSFORMATION; HUMORAL IMMUNITY; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOGENICITY; IMMUNOGLOBULIN BLOOD LEVEL; INFECTION CONTROL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RHABDOMYOSARCOMA; SIGNAL TRANSDUCTION; SPLEEN CELL; TOMATO; TRANSGENIC PLANT;

ADMINISTRATION, ORAL; ANIMALS; ANTIBODIES, VIRAL; CAPSID PROTEINS; CYTOKINES; ENTEROVIRUS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; LYCOPERSICON ESCULENTUM; LYMPHOCYTES; MICE; MICE, INBRED BALB C; PLANTS, GENETICALLY MODIFIED; PROTEIN SORTING SIGNALS; SPLEEN; VACCINES, EDIBLE; VACCINES, SYNTHETIC; VIRAL VACCINES;

EID: 33644913110     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2005.12.047     Document Type: Article

References (34)

1. H.S. Mason, H. Warzecha, T. Mor, and C.J. Arntzen Edible plant vaccines: applications for prophylactic and therapeutic molecular medicine Trends Mol Med 8 2002 324 329
2. Q. Kong, L. Richter, Y.F. Yang, C.J. Arntzen, H.S. Mason, and Y. Thanavala Oral immunization with hepatitis B surface antigen expressed in transgenic plants Proc Natl Acad Sci USA 98 2001 11539 11544
3. T.A. Haq, H.S. Mason, J.D. Clements, and C.J. Arntzen Oral immunization with a recombinant bacterial antigen produced in transgenic plants Science 268 1995 714 716
4. J. Kapusta, A. Modelska, M. Figlerowicz, T. Pniewski, M. Letellier, and O. Lisowa A plant-derived edible vaccine against hepatitis B virus FASEB J 13 1999 1796 1799
5. T.G. Lauterslager, D.E. Florack, T. van der Wal, J.J. Molthoff, WJ.P. Langeveld, and D. Bosch Oral immunisation of naive and primed animals with transgenic potato tubers expressing LT-B Vaccine 19 2001 2749 2755
6. E.C. Lavelle, G. Grant, A. Pusztai, and U.D.T. Pfuller O'Hagan Mucosal immunogenicity of plant lectins in mice Immunology 99 2000 30 37
7. H. Warzecha, H.S. Mason, C. Lane, A. Tryggvesson, E. Rybicki, and A.L. Williamson Oral immunogenicity of human papillomavirus-like particles expressed in potato J Virol 77 2003 8702 8711
8. S.R. Shih, M.S. Ho, K.H. Lin, S.L. Wu, Y.T. Chen, and C.N. Wu Genetic analysis of enterovirus 71 isolated from fatal and non-fatal cases of hand, foot and mouth disease during an epidemic in Taiwandkjdot Virus Res 68 2000 127 136
9. T.Y. Lin, L.Y. Chang, S.H. Hsia, Y.C. Huang, C.H. Chiu, and C. Hsueh The 1998 enterovirus 71 outbreak in Taiwan: pathogenesis and management Clin Infect Dis 34 2002 S52 S57
10. S.R. Shih, Y.S. Li, C.C. Chiou, P.C. Suen, T.Y. Lin, and L.Y. Chang Expression of capsid protein VP1 for use as antigen for the diagnosis of enterovirus 71 infection J Med Virol 61 2000 228 234
11. C.K. Yu, C.C. Chen, C.L. Chen, J.R. Wang, C.C. Liu, and J.J. Yan Neutralizing antibody provided protection against enterovirus type 71 lethal challenges in neonatal mice J Biomed Sci 7 2000 523 528
12. A. Henke, R. Zell, and A. Stelzner DNA vaccine-mediated immune responses in Coxsackie virus B3-infected mice Antiviral Res 49 2001 49 54
13. C.N. Wu, Y.C. Lin, C. Fann, N.S. Liao, S.R. Shih, and M.S. Ho Protection against lethal enterovirus 71 infection in newborn mice by passive immunization with subunit VP1 vaccines and inactivated virus Vaccine 20 2002 895 904
14. C. Carrillo, A. Wigdorovitz, J.C. Oliveros, P.I. Zamorano, A.M. Sadir, and N. Gomez Protective immune response to foot-and-mouth disease virus with VP1 expressed in transgenic plants J Virol 72 1998 1688 1690
15. D. Chargelegue, P. Obregon, and P.M. Drake Transgenic plants for vaccine production: expectations and limitations Trends Plant Sci 6 2001 495 496
16. G. Giddings, G. Allison, D. Brooks, and A. Carter Transgenic plants as factories for biopharmaceuticals Nat Biotechnol 18 2000 1151 1155
17. T. Arakawa, D.K. Chong, and W.H. Langridge Efficacy of a food plant-based oral cholera toxin B subunit vaccine Nat Biotechnol 16 1998 292 297
18. H.S. Mason, T.A. Haq, J.D. Clements, and C.J. Arntzen Edible vaccine protects mice against Escherichia coli heat-labile enterotoxin (LT): potatoes expressing a synthetic LT-B gene Vaccine 16 1998 1336 1343
19. L.J. Richter, Y. Thanavala, C.J. Arntzen, and H.S. Mason Production of hepatitis B surface antigen in transgenic plants for oral immunization Nat Biotechnol 18 2000 1167 1171
20. S.Y. Bednarek, T.A. Wilkins, J.E. Dombrowski, and N.V. Raikhel A carboxyl-terminal propeptide is necessary for proper sorting of barley lectin to vacuoles of tobacco Plant Cell 2 1990 1145 1155
21. J.M. Neuhaus, and J.C. Rogers Sorting of proteins to vacuoles in plant cells Plant Mol Biol 38 1998 127 144
22. S.T. Jeng, and C.Y. Yen Effects of Rho-independent terminators on the expression of a plant gene Physiol Plant 108 2000 171 179
23. S.A. Jobling, and L. Gehrke Enhanced translation of chimaeric messenger RNAs containing a plant viral untranslated leader sequence Nature 325 1987 622 625
24. K. Matsuoka, and K. Nakamura Propeptide of a precursor to a plant vacuolar protein required for vacuolar targeting Proc Natl Acad Sci USA 88 1991 834 838
25. M.M. Bradford A rapid and sensitive method for the quantisation of microgram quantities of protein utilizing the principle of protein dye binding Anal Biochem 72 1976 248 254
26. E.M. Herman, B.W. Taqul, L.M. Hoffman, S.E. Kjemtrup, and M.J. Chrispeels Retention of phytohemagglutinin with carboxyterminal tetrapeptide KDEL in the nuclear envelope and the endoplasmic reticulum Plantation 182 1990 305 312
27. S.E. Coffin, S.L. Clark, N.A. Bos, J.O. Brubaker, and P.A. Offit Migration of antigen-presenting B cells from peripheral to mucosal lymphoid tissues may induce intestinal antigen-specific IgA following parenteral immunization J Immunol 163 1999 3064 3070
28. A.M. Walmsley, D.D. Kirk, and H.S. Mason Passive immunization of mice pups through oral immunization of dams with a plant-derived vaccine Immunol Lett 86 2003 71 76
29. M.J. Zhang, M.X. Wang, S.Z. Jiang, Z.Z. Xiu, and W.Y. Ma Preparation and characterization of the monoclonal antibodies against Japanese encephalitis virus Acta Virol 36 1992 533 540
30. K.G. Amemiya, V. Bush, D. DeShazer, and D.M. Waag Nonviable Burkholderia mallei induces a mixed Th1- and Th2-like cytokine response in BALB/c mice Infect Immun 70 2002 2319 2325
31. A.K. Abbas, K.M. Murphy, and A. Sher Functional diversity of helper T lymphocytes Nature 383 1996 787 793
32. N.E. Street, and T.R. Mosmann Functional diversity of T-lymphocytes due to secretion of different cytokine patterns FASEB J 5 1991 171 177
33. J.S. Sandhu, S.F. Krasnyanski, L.L. Domier, S.S. Korban, M.D. Osadjan, and D.E. Buetow Oral immunization of mice with transgenic tomato fruit expressing respiratory syncytial virus-F protein induces a systemic immune response Transgenic Res 9 2000 127 135
34. F. Sala, M.M. Rigano, A. Barbante, B. Basso, A.M. Walmsley, and S. Castiglione Vaccine antigen production in transgenic plants: strategies, gene constructs and perspectives Vaccine 21 2003 803 808