Oral immunogenicity of human papillomavirus-like particles expressed in potato

Journal of Virology

Volumn 77, Issue 16, 2003, Pages 8702-8711

  Warzecha, Heribert ^a,f   Mason, Hugh S ^a,g   Lane, Christopher ^b   Tryggvesson, Anders ^a   Rybicki, Edward ^c   Williamson, Anna Lise ^c   Clements, John D ^d   Rose, Robert C ^b,e  

^a United States Department of Agriculture Agricultural Research Service and Boyce Thompson Institute for Plant Research   (United States)

^b UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^c UNIVERSITY OF CAPE TOWN   (South Africa)

^d TULANE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^e UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^f Lehrst F Pharmazeutische Biologie   (Germany)

^g ARIZONA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; CANCER VACCINE; CAPSID PROTEIN; L1 PROTEIN; UNCLASSIFIED DRUG; VIRUS PROTEIN; VIRUS VACCINE;

ANIMAL EXPERIMENT; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; FEMALE; HUMORAL IMMUNITY; IMMUNOGENICITY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PLANT CELL; PLANT GROWTH; POTATO; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; TRANSGENIC PLANT; VACCINATION; VIRUS ASSEMBLY; VIRUS PARTICLE; WART VIRUS;

ADMINISTRATION, ORAL; ANIMALS; BASE SEQUENCE; DNA, VIRAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; MUTAGENESIS; PAPILLOMAVIRIDAE; PLANTS, GENETICALLY MODIFIED; RECOMBINANT PROTEINS; SOLANUM TUBEROSUM; VIRAL VACCINES; VIRION;

EID: 0042709462     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.77.16.8702-8711.2003     Document Type: Article

References (44)

1. An, G. 1985. High efficiency transformation of cultured tobacco cells. Plant Physiol. 79:568-570.
2. Ausubel, F. M., R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl. 1994. Current protocols in molecular biology, vol. 3. John Wiley & Sons, Brooklyn, N.Y.
3. Balmelli, C., R. Roden, A. Potts, J. Schiller, P. De Grandi, and D. Nardelli-Haefliger. 1998. Nasal immunization of mice with human papillomavirus type 16 virus-like particles elicits neutralizing antibodies in mucosal secretions. J. Virol. 72:8220-8229.
4. Becker, D., E. Kemper, J. Schell, and R. Masterson. 1992. New plant binary vectors with selectable markers located proximal to the left T-DNA border. Plant Mol. Biol. 20:1195-1197.
5. Bonnez, W., C. Da Rin, R. C. Rose, and R. C. Reichman. 1991. Use of human papillomavirus type 11 virions in an ELISA to detect specific antibodies in humans with condylomata acuminata. J. Gen. Virol. 72:1343-1347.
6. Bonnez, W., R. C. Rose, and R. C. Reichman. 1992. Antibody-mediated neutralization of human papillomavirus type 11 (HPV-11) infection in the nude mouse: detection of HPV-11 mRNAs. J. Infect. Dis. 165:376-380.
7. Bosch, F. X., A. Lorincz, N. Munoz, C. J. Meijer, and K. V. Shah. 2002. The causal relation between human papillomavirus and cervical cancer. J. Clin. Pathol. 55:244-265.
8. Chiu, W., Y. Niwa, W. Zeng, T. Hirano, H. Kobayashi, and J. Sheen. 1996. Engineered GFP as a vital reporter in plants. Curr. Biol. 6:325-330.
9. Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156-159.
10. Dillner, L., P. Heino, J. Moreno-Lopez, and J. Dillner. 1991. Antigenic and immunogenic epitopes shared by human papillomavirus type 16 and bovine, canine, and avian papillomaviruses. J. Virol. 65:6862-6871.
11. Dupuy, C., D. Buzoni-Gatel, A. Touze, D. Bout, and P. Coursaget. 1999. Nasal immunization of mice with human papillomavirus type 16 (HPV-16) virus-like particles or with the HPV-16 Li gene elicits specific cytotoxic T lymphocytes in vaginal draining lymph nodes. J. Virol. 73:9063-9071.
12. Evans, T. G., W. Bonnez, R. C. Rose, S. Koenig, L. Demeter, J. A. Suzich, D. O'Brien, M. Campbell, W. I. White, J. Balsley, and R. C. Reichman. 2001. A phase 1 study of a recombinant viruslike particle vaccine against human papillomavirus type 11 in healthy adult volunteers. J. Infect. Dis. 183:1485-1493.
13. Gerber, S., C. Lane, D. Brown, E. Lord, M. DiLorenzo, J. D. Clements, A. L. Williamson, and R. C. Rose. 2001. Human papillomavirus virus-like particles are efficient oral immunogens when co-administered with Escherichia coli heat-labile enterotoxin mutant R192G or CpG DNA. J. Virol. 75:4752-4760.
14. Giroglou, T., M. Sapp, C. Lane, C. Fligge, N. D. Christensen, R. E. Streeck, and R. C. Rose. 2001. Immunological analyses of human papillomavirus capsids. Vaccine 19:1783-1793.
15. Haq, T. A., H. S. Mason, J. D. Clements, and C. J. Arntzen. 1995. Oral immunization with a recombinant bacterial antigen produced in transgenic plants. Science 268:714-716.
16. Harro, C. D., Y. Y. Pang, R. B. Roden, A. Hildesheim, Z. Wang, M. J. Reynolds, T. C. Mast, R. Robinson, B. R. Murphy, R. A. Karron, J. Dillner, J. T. Schiller, and D. R. Lowy. 2001. Safety and immunogenicity trial in adult volunteers of a human papillomavirus 16 L1 virus-like particle vaccine. J. Natl. Cancer Inst. 93:284-292.
17. Kapusta, J., A. Modelska, M. Figlerowicz, T. Pniewski, M. Letellier, O. Lisowa, V. Yusibov, H. Koprowski, A. Plucienniczak, and A. B. Legocki. 1999. A plant-derived edible vaccine against hepatitis B virus. FASEB J. 13:1796-1799.
18. Koutsky, L. A., K. A. Ault, C. M. Wheeler, D. R. Brown, E. Barr, F. B. Alvarez, L. M. Chiacchierini, and K. U. Jansen. 2002. A controlled trial of a human papillomavirus type 16 vaccine. N. Engl. J. Med. 347:1645-1651.
19. Koziel, M. G., N. B. Carozzi, and N. Desai. 1996. Optimizing expression of transgenes with an emphasis on post-transcriptional events. Plant Mol. Biol. 32:393-405.
20. Lowy, D. R., and P. M. Howley. 2001. Papillomaviruses, p. 2231-2264. In D. M. Knipe and P. M. Howley (ed.), Fields virology, 4th ed., vol. 2. Lippincott Williams & Wilkins, Philadelphia, Pa.
21. Mason, H. S., T. A. Haq, J. D. Clements, and C. J. Arntzen. 1998. Edible vaccine protects mice against Escherichia coli heat-labile enterotoxin (LT): potatoes expressing a synthetic LT-B gene. Vaccine 16:1336-1343.
22. Mason, H. S., H. Warzecha, T. Mor, and C. J. Arntzen. 2002. Edible plant vaccines: applications for prophylactic and therapeutic molecular medicine. Trends Mol. Med. 8:324-329.
23. Merle, E., R. C. Rose, L. LeRoux, and J. Moroianu. 1999. Nuclear import of HPV11 L1 capsid protein is mediated by karyopherin alpha 2/beta 1 heterodimers. J. Cell. Biochem. 74:628-637.
24. Meyer, P. 1995. Understanding and controlling transgene expression. Trends Biotechnol. 13:332-337.
25. Paintsil, J., M. Muller, M. Picken, L. Gissmann, and J. Zhou. 1996. Carboxyl terminus of bovine papillomavirus type-1 L1 protein is not required for capsid formation. Virology 223:238-244.
26. Rogers, J. C., D. Dean, and G. R. Heck. 1985. Aleurain: a barley thiol protease closely related to mammalian cathepsin H. Proc. Natl. Acad. Sci. USA 82:6512-6516.
27. Rose, R. C. 2002. Human papillomavirus immunology and vaccine development, p. 165-187. In D. McCance (ed.), Human papillomaviruses, vol. 8. Elsevier, Amsterdam, The Netherlands.
28. Rose, R. C., W. Bonnez, C. Da Rin, D. J. McCance, and R. C. Reichman. 1994. Serological differentiation of human papillomavirus types 11, 16 and 18 using recombinant virus-like particles. J. Gen. Virol. 75:2445-2449.
29. Rose, R. C., W. Bonnez, R. C. Reichman, and R. L. Garcea. 1993. Expression of human papillomavirus type 11 L1 protein in insect cells: in vivo and in vitro assembly of viruslike particles. J. Virol. 67:1936-1944.
30. Rose, R. C., W. Bonnez, D. G. Strike, and R. C. Reichman. 1990. Expression of the full-length products of the human papillomavirus type 6b (HPV-6b) and HPV-11 L2 open reading frames by recombinant baculovirus, and antigenic comparisons with HPV-11 whole virus particles. J. Gen. Virol. 71:2725-2729.
31. Rose, R. C., C. Lane, S. Wilson, J. A. Suzich, E. Rybicki, and A. L. Williamson. 1999. Oral vaccination of mice with human papillomavirus virus-like particles induces systemic virus-neutralizing antibodies. Vaccine 17:2129-2135.
32. Rose, R. C., R. C. Reichman, and W. Bonnez. 1994. Human papillomavirus (HPV) type 11 recombinant virus-like particles induce the formation of neutralizing antibodies and detect HPV-specific antibodies in human sera. J. Gen. Virol. 75:2075-2079.
33. Rose, R. C., W. I. White, M. Li, J. A. Suzich, C. Lane, and R. L. Garcea. 1998. Human papillomavirus type 11 recombinant L1 capsomeres induce virus-neutralizing antibodies. J. Virol. 72:6151-6154.
34. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
35. Sanford, J. C., F. D. Smith, and J. A. Russell. 1993. Optimizing the biolistic process for different biological applications. Methods Enzymol. 217:483-509.
36. Schiller, J., and D. Lowy. 2001. Papillomavirus-like particle vaccines. J. Natl. Cancer Inst. Monogr. 28:50-54.
37. Schiller, J. T. 1999. Papillomavirus-like particle vaccines for cervical cancer. Mol. Med. Today 5:209-215.
38. Stemmer, W. P., A. Crameri, K. D. Ha, T. M. Brennan, and H. L. Heyneker. 1995. Single-step assembly of a gene and entire plasmid from large numbers of oligodeoxyribonucleotides. Gene 164:49-53.
39. Strike, D. G., W. Bonnez, R. C. Rose, and R. C. Reichman. 1989. Expression in Escherichia coli of seven DNA fragments comprising the complete L1 and L2 open reading frames of human papillomavirus type 6b and localization of the 'common antigen' region. J. Gen. Virol. 70:543-555.
40. Tacket, C. O., H. S. Mason, G. Losonsky, J. D. Clements, M. M. Levine, and C. J. Arntzen. 1998. Immunogenicity in humans of a recombinant bacterial antigen delivered in a transgenic potato. Nat. Med. 4:607-609.
41. Tacket, C. O., H. S. Mason, G. Losonsky, M. K. Estes, M. M. Levine, and C. J. Arntzen. 2000. Human immune responses to a novel Norwalk virus vaccine delivered in transgenic potatoes. J. Infect. Dis. 182:302-305.
42. Wada, K., S. Aota, R. Tsuchiya, F. Ishibashi, T. Gojobori, and T. Ikemura. 1990. Codon usage tabulated from the GenBank genetic sequence data. Nucleic Acids Res. 18(Suppl.):2367-2411.
43. Walboomers, J. M., M. V. Jacobs, M. M. Manos, F. X. Bosch, J. A. Kummer, K. V. Shah, P. J. Snijders, J. Peto, C. J. Meijer, and N. Munoz. 1999. Human papillomavirus is a necessary cause of invasive cervical cancer worldwide. J. Pathol. 189:12-19.
44. White, W. I., S. D. Wilson, W. Bonnez, R. C. Rose, S. Koenig, and J. A. Suzich. 1998. In vitro infection and type-restricted antibody-mediated neutralization of authentic human papillomavirus type 16. J. Virol. 72:959-964.