Complementary Gli activity mediates early patterning of the mouse visual system

Developmental Dynamics

Volumn 235, Issue 3, 2006, Pages 594-605

  Furimsky, Marosh ^a   Wallace, Valerie A ^a,b  

^a OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF OTTAWA   (Canada)

Author keywords

Gli1; Gli2; Gli3; Mouse; Optic stalk; Pax2; Pax6; Retina; Sonic hedgehog

Indexed keywords

DIGOXIGENIN; SONIC HEDGEHOG PROTEIN; T BOX TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GLI1; TRANSCRIPTION FACTOR GLI2; TRANSCRIPTION FACTOR GLI3; TRANSCRIPTION FACTOR PAX2; TRANSCRIPTION FACTOR PAX6; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EMBRYO; EMBRYO PATTERN FORMATION; EYE DEVELOPMENT; FEMALE; GENE EXPRESSION REGULATION; GENE REPRESSION; IN SITU HYBRIDIZATION; MALE; MOUSE; NONHUMAN; OPTIC DISK CUP; PHENOTYPE; PIGMENT EPITHELIUM; PRIORITY JOURNAL; RETINA DEVELOPMENT; RETINA INNER PLEXIFORM LAYER; VISUAL SYSTEM;

ANIMALS; BODY PATTERNING; EYE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEDGEHOG PROTEINS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MICE; MICE, NEUROLOGIC MUTANTS; MUTATION; NERVE TISSUE PROTEINS; OPTIC NERVE; REPRESSOR PROTEINS; TRANS-ACTIVATORS;

ANIMALIA; ERINACEIDAE; MYOXUS; VERTEBRATA;

EID: 33644898522     PISSN: 10588388     EISSN: 10970177     Source Type: Journal    
DOI: 10.1002/dvdy.20658     Document Type: Article

References (57)

1. Amato MA, Boy S, Perron M. 2004. Hedgehog signaling in vertebrate eye development: a growing puzzle. Cell Mol Life Sci 61:899-910,
2. Ashery-Padan R, Gruss P. 2001. Pax6 lights-up the way for eye development. Curr Opin Cell Biol 13:706-714.
3. Aza-Blanc P, Lin HY, Ruiz i Altaba A, Kornberg TB. 2000. Expression of the vertebrate Gli proteins in Drosophila reveals a distribution of activator and repressor activities. Development 127:4293-4301.
4. Bai CB, Auerbach W, Lee JS, Stephen D, Joyner AL. 2002. Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathway. Development 129:4753-4761.
5. Bai CB, Stephen D, Joyner AL. 2004. All mouse ventral spinal cord patterning by hedgehog is Gli dependent and involves an activator function of Gli3. Dev Cell 6:103-115.
6. Barbieri AM, Lupo G, Bulfone A, Andreazzoli M, Mariani M, Fougerousse F, Consalez GG, Borsani G, Beckmann JS, Barsacchi G, Ballabio A, Banfi S. 1999. A homeobox gene, vax2, controls the patterning of the eye dorsoventral axis. Proc Natl Acad Sci U S A 96:10729-10734.
7. Baumer N, Marquardt T, Stoykova A, Spieler D, Treichel D, Ashery-Padan R, Gruss P. 2003. Retinal pigmented epithelium determination requires the redundant activities of Pax2 and Pax6. Development 130:2903-2915.
8. Bertuzzi S, Hindges R, Mui SH, O'Leary DD, Lemke G. 1999. The homeodomain protein vax1 is required for axon guidance and major tract formation in the developing forebrain. Genes Dev 13:3092-3105.
9. Cavodeassi F, Carreira-Barbosa F, Young RM, Concha ML, Allende ML, Houart C, Tada M, Wilson SW. 2005. Early stages of zebrafish eye formation require the coordinated activity of Wnt11, Fz5, and the Wnt/beta-catenin pathway. Neuron 47:43-56.
10. Chiang C, Litingtung Y, Lee E, Young KE, Corden JL, Westphal H, Beachy PA. 1996. Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function. Nature 383:407-413.
11. Chow RL, Lang RA. 2001. Early eye development in vertebrates. Annu Rev Cell Dev Biol 17:255-296.
12. Dakubo GD, Wang YP, Mazerolle C, Campsall K, McMahon AP, Wallace VA. 2003. Retinal ganglion cell-derived sonic hedgehog signaling is required for optic disc and stalk neuroepithelial cell development. Development 130:2967-2980.
13. Ding Q, Motoyama J, Gasca S, Mo R, Sasaki H, Rossant J, Hui CC. 1998. Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice. Development 125:2533-2543.
14. Ekker SC, Ungar AR, Greenstein P, von Kessler DP, Porter JA, Moon RT, Beachy PA. 1995. Patterning activities of vertebrate hedgehog proteins in the developing eye and brain. Cur. Biol. 5:944-955.
15. Franz T, Besecke A. 1991. The development of the eye in homozygotes of the mouse mutant Extra-toes. Anat Embryol (Berl) 184:355-361.
16. Hallonet M, Hollemann T, Pieler T, Gruss P. 1999. Vax1, a novel homeobox-containing gene, directs development of the basal forebrain and visual system. Genes Dev 13:3106-3114.
17. Huh S, Hatini V, Marcus RC, Li SC, Lai E. 1999. Dorsal-ventral patterning defects in the eye of BF-1-deficient mice associated with a restricted loss of shh expression. Dev Biol 211:53-63.
18. Hui CC, Joyner AL. 1993. A mouse model of greig cephalopolysyndactyly syndrome: the extra-toesJ mutation contains an intragenic deletion of the Gli3 gene. Nat Genet 3:241-246.
19. Hui CC, Slusarski D, Platt KA, Holmgren R, Joyner AL. 1994. Expression of three mouse homologs of the Drosophila segment polarity gene cubitus interruptus, Gli, Gli-2, and Gli-3, in ectoderm- and mesoderm-derived tissues suggests multiple roles during postimplantation development. Dev Biol 162:402-413.
20. Ingham PW, McMahon AP. 2001. Hedgehog signaling in animal development: paradigms and principles. Genes Dev 15: 3059-3087.
21. Jensen AM, Wallace VA. 1997. Expression of Sonic hedgehog and its putative role as a precursor cell mitogen in the developing mouse retina. Development 124: 363-371.
22. Levine EM, Roelink H, Turner J, Reh TA. 1997. Sonic hedgehog promotes rod photoreceptor differentiation in mammalian retinal cells in vitro. J Neurosci 17:6277-6288.
23. Li H, Tierney C, Wen L, Wu JY, Rao Y. 1997. A single morphogenetic field gives rise to two retina primordia under the influence of the prechordal plate. Development 124:603-615.
24. Litingtung Y, Chiang C. 2000. Specification of ventral neuron types is mediated by an antagonistic interaction between Shh and Gli3. Nat Neurosci 3:979-985.
25. Lupo G, Liu Y, Qiu R, Chandraratna RA, Barsacchi G, He RQ, Harris WA. 2005. Dorsoventral patterning of the Xenopus eye: a collaboration of Retinoid, Hedgehog and FGF receptor signaling. Development 132:1737-1748.
26. Macdonald R, Barth KA, Xu Q, Holder N, Mikkola I, Wilson SW. 1995. Midline signalling is required for Pax gene regulation and patterning of the eyes. Development 121:3267-3278.
27. Marti E, Takada R, Bumcrot D, Sasaki H, McMahon A. 1995. Distribution of sonic hedgehog peptides in the developing chick and mouse embryo. Development 121:2537-2547.
28. Matise MP, Epstein DJ, Park HL, Platt KA, Joyner AL. 1998. Gli2 is required for induction of floor plate and adjacent cells, but not most ventral neurons in the mouse central nervous system. Development 125:2759-2770.
29. Mo R, Freer AM, Zinyk DL, Crackower MA, Michaud J, Heng HH, Chik KW, Shi XM, Tsui LC, Cheng SH, Joyner AL, Hui C. 1997. Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and development. Development 124:113-123.
30. Mui SH, Hindges R, O'Leary DD, Lemke G, Bertuzzi S. 2002. The homeodomain protein Vax2 patterns the dorsoventral and nasotemporal axes of the eye. Development 129:797-804.
31. Mui SH, Kim JW, Lemke G, Bertuzzi S. 2005. Vax genes ventralize the embryonic eye. Genes Dev 19:1249-1259.
32. Ohkubo Y, Chiang C, Rubenstein JL. 2002. Coordinate regulation and synergistic actions of BMP4, SHH and FGF8 in the rostral prosencephalon regulate morphogenesis of the telencephalic and optic vesicles. Neuroscience 111:1-17.
33. Persson M, Stamataki D, te Welscher P, Andersson E, Bose J, Ruther U, Ericson J, Briscoe J. 2002. Dorsal-ventral patterning of the spinal cord requires Gli3 transcriptional repressor activity. Genes Dev 16:2865-2878.
34. Pichaud F, Desplan C. 2002. Pax genes and eye organogenesis. Curr Opin Genet Dev 12:430-434.
35. Pichaud F, Treisman JE, Desplan C. 2001. Reinventing a common strategy for patterning the eye. Cell 105:9-12.
36. Rallu M, Machold R, Gaiano N, Corbin JG, McMahon AP, Fishell G. 2002. Dorsoventral patterning is established in the telencephalon of mutants lacking both Gli3 and Hedgehog signaling. Development 129:4963-4974.
37. Roessler E, Belloni E, Gaudenz K, Jay P, Berta P, Scherer SW, Tsui LC, Muenke M. 1996. Mutations in the human Sonic Hedgehog gene cause holoprosencephaly. Nat Genet 14:357-360.
38. Ruiz i Altaba A. 1999a. Gli proteins and Hedgehog signaling: development and cancer. Trends Genet 15:418-425.
39. Ruiz i Altaba A. 1999b. Gli proteins encode context-dependent positive and negative functions: implications for development and disease. Development 126:3205-3216.
40. Ruiz i Altaba A, Sanchez P, Dahmane N. 2002. Gli and hedgehog in cancer: tumours, embryos and stem cells. Nat Rev Cancer 2:361-372.
41. Sasagawa S, Takabatake T, Takabatake Y, Muramatsu T, Takeshima K. 2002. Axes establishment during eye morphogenesis in Xenopus by coordinate and antagonistic actions of BMP4, Shh, and RA. Genesis 33:86-96.
42. Sasaki H, Nishizaki Y, Hui C, Nakafuku M, Kondoh H. 1999. Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: implication of Gli2 and Gli3 as primary mediators of Shh signaling. Development 126:3915-3924.
43. Schedl A, Ross A, Lee M, Engelkamp D, Rashbass P, van Heyningen V, Hastie ND. 1996. Influence of PAX6 gene dosage on development: overexpression causes severe eye abnormalities. Cell 86:71-82.
44. Schell-Apacik C, Rivero M, Knepper JL, Roessler E, Muenke M, Ming JE. 2003. SONIC HEDGEHOG mutations causing human holoprosencephaly impair neural patterning activity. Hum Genet 113:170-177.
45. Schimmenti LA, de la Cruz J, Lewis RA, Karkera JD, Manligas GS, Roessler E, Muenke M. 2003. Novel mutation in sonic hedgehog in non-syndromic colobomatous microphthalmia. Am J Med Genet 116A:215-221.
46. Schwarz M, Cecconi F, Bernier G, Andrejewski N, Kammandel B, Wagner M, Gruss P. 2000. Spatial specification of mammalian eye territories by reciprocal transcriptional repression of Pax2 and Pax6. Development 127:4325-4334.
47. Stamataki D, Ulloa F, Tsoni SV, Mynett A, Briscoe J. 2005. A gradient of Gli activity mediates graded Sonic Hedgehog signaling in the neural tube. Genes Dev 19: 626-641.
48. St-Jacques B, Dassule HR, Karavanova I, Botchkarev VA, Li J, Danielian PS, McMahon JA, Lewis PM, Paus R, McMahon AP. 1998. Sonic hedgehog signaling is essential for hair development. Curr Biol 8:1058-1068.
49. Stone D, Rosenthal A. 2000. Achieving neuronal patterning by repression. Nat Neurosci 3:967-969.
50. Take-uchi M, Clarke JD, Wilson SW. 2003. Hedgehog signalling maintains the optic stalk-retinal interface through the regulation of Vax gene activity. Development 130:955-968.
51. Uemonsa T, Sakagami K, Yasuda K, Araki M. 2002. Development of dorsal-ventral polarity in the optic vesicle and its presumptive role in eye morphogenesis as shown by embryonic transplantation and in ovo explant culturing. Dev Biol 248: 319-330.
52. Wallace VA, Raff MC. 1999. A role for Sonic hedgehog in axon-to-astrocyte signalling in the rodent optic nerve. Development 126:2901-2909.
53. Wang B, Fallon JF, Beachy PA. 2000. Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb. Cell 100:423-434.
54. Wang YP, Dakubo G, Howley P, Campsall KD, Mazarolle CJ, Shiga SA, Lewis PM, McMahon AP, Wallace VA. 2002. Development of normal retinal organization depends on Sonic hedgehog signaling from ganglion cells. Nat Neurosci 5:831-832.
55. Wang Y, Dakubo GD, Thurig S, Mazerolle CJ, Wallace VA. 2005. Retinal ganglion cell-derived Sonic hedgehog locally controls proliferation and the timing of RGC development in the embryonic mouse retina. Development 132:5103-5113.
56. Wild A, Kalff-Suske M, Vortkamp A, Bornholdt D, Konig R, Grzeschik KH. 1997. Point mutations in human GLI3 cause Greig syndrome. Hum Mol Genet 6:1979-1984.
57. Zhang XM, Yang XJ. 2001. Regulation of retinal ganglion cell production by Sonic hedgehog. Development 128:943-957.