A computer-aided approach to compare the production economics of fed-batch and perfusion culture under uncertainty

Biotechnology and Bioengineering

Volumn 93, Issue 4, 2006, Pages 687-697

  Lim, Ai Chye ^a   Washbrook, John ^a   Titchener Hooker, Nigel John ^a   Farid, Suzanne S ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Biotechnology; Cell culture; Computer aided simulation; Decision support; Fed batch; Perfusion; Process economics; Risk; Uncertainty

Indexed keywords

BIOTECHNOLOGY; CELL CULTURE; DECISION SUPPORT SYSTEMS; MONTE CARLO METHODS; PROBABILITY; PRODUCTION ENGINEERING; RISKS;

COMPUTER-AIDED SIMULATION; FED-BATCH; PERFUSION; PROCESS ECONOMICS; UNCERTAINTY;

COMPUTER AIDED DESIGN;

MONOCLONAL ANTIBODY;

ARTICLE; CAPITAL; COMPUTER AIDED DESIGN; CONTAMINATION; COST BENEFIT ANALYSIS; DECISION MAKING; ECONOMICS; EQUIPMENT; FED BATCH CULTURE; FILTER; INVESTMENT; MONTE CARLO METHOD; PERFUSION; PRODUCTIVITY; RISK ASSESSMENT;

ANTIBODIES, MONOCLONAL; BACTERIOLOGICAL TECHNIQUES; BIOREACTORS; COMPUTER SIMULATION; COSTS AND COST ANALYSIS; DECISION SUPPORT TECHNIQUES; EQUIPMENT FAILURE; MONTE CARLO METHOD; PERFUSION; TECHNOLOGY, PHARMACEUTICAL;

MAMMALIA; NUCLEOPOLYHEDROVIRUS;

EID: 33644896550     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.20757     Document Type: Article

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