Phosvitin phosphopeptides increase iron uptake in a Caco-2 cell monolayer model

International Journal of Food Science and Technology

Volumn 41, Issue 4, 2006, Pages 455-458

  Feng, Fengqin ^a   Mine, Yoshinori ^a  

^a UNIVERSITY OF GUELPH   (Canada)

Author keywords

59Fe; Caco 2 cell; Iron uptake; Phosphopeptides; Phosvitin

Indexed keywords

EID: 33644888299     PISSN: 09505423     EISSN: 13652621     Source Type: Journal    
DOI: 10.1111/j.1365-2621.2005.01073.x     Document Type: Review

References (19)

1. Aisen, P. & Listowsky, I. (1980). Iron transport and storage proteins. Annual Review of Biochemistry, 49, 357-393.
2. Albright, K.J., Gordon, D.T. & Cotterill, O.J. (1984). Release of iron from phosvitin by heat and food additives. Journal of Food Science, 49, 78-81.
3. Alvarez-Hernandez, X., Smith, M. & Glass, J. (1994). Regulation of iron uptake and transport by transferrin in Caco-2 cells, an intestinal cell line. Biochimica Biophysica Acta, 1192, 215-222.
4. Beard, J.L. (2001). Iron biology in immune function, muscle metabolism and neuronal functioning. American Journal of Clinical Nutrition, 131 (Suppl.), 568S-580S.
5. Gerber, H.W. & Jost, R. (1986). Casein phosphopeptides: their effect in calcification in vitro cultured embryonic rat bone. Calcified Tissue International, 38, 350-357.
6. Glahn, R.P., Lai, C., Hsu, J., Thompson, J.F., Guo, M. & Van Campen, D.R. (1998a). Decreased citrate improves iron availability from infant formula: application of an in vitro digestion/Caco-2 cell culture model. Journal of Nutrition, 128, 257-264.
7. Glahn, R.P., Lee, O.A., Yeung, A., Goldman, M.I. & Miller, D.D. (1998b). Caco-2 cell ferritin formation predicts nonradiolabeled food iron availability in an in vitro digestion/Caco-2 cell culture model. Journal of Nutrition, 128, 1555-1561.
8. Han, O., Failla, M., Hill, A., Morris, E. & Smith, J. (1995). Reduction of Fe(III) is required for uptake of nonheme iron by Caco-2 cells. Journal of Nutrition, 125, 1291-1299.
9. Jiang, B. & Mine, Y. (2000). Preparation of novel functional oligophosphopeptides from hen egg yolk phosvitin. Journal of Agriculture and Food Chemistry, 48, 990-994.
10. Jiang, B. & Mine, Y. (2001). Phosphopeptides derived from hen egg yolk phosvitin: effect of molecular size on the calcium-binding properties. Bioscience Biotechnology and Biochemistry, 65, 1187-1190.
11. Meisel, H. & Schlimme, E. (1990). Milk proteins: precursors of bioactive peptides. Trends in Food Science and Technology, 1, 41-43.
12. Morris, E.R. & Greece, F.E. (1972). Utilization of the iron of egg yolk for hemoglobin formation by the growing rat. Journal of Nutrition, 102, 901-908.
13. Naito, H. (1990). Casein phosphopeptide: intro-intestenal formation and significance in the bioavailability of calcium. In: Nutrition, Protein and Amino Acids (edited by A. Roshida, H. Nito, Y. Niiyama & T. Suich). Pp. 207-220. Tokyo: Japan Scientific Society Press.
14. Pinto, M., Robine-Leon, S., Appay, M.-D. et al. (1983). Enterocyte-like differentiation and polarization of the human colon carcinoma cell line Caco-2 in culture. Biology of the Cell, 47, 323-330.
15. Sato, R., Noguchi, T. & Naito, H. (1986). Casein phosphopeptide (CPP) enhances calcium absorption from ligated segment of rat small intestine. Journal of Nutritional Science and Vitaminology, 32, 67-76.
16. Sato, R., Shindo, M., Gunshin, H., Noguchi, T. & Naito, H. (1991). Characterization of phosphopeptide derived from bovine β-casein: an inhibitor to intra-intestinal precipitation of calcium phosphate. Biochimica Biophysica Acta, 1077, 413-415.
17. Tapia, V. & Nuñez, M.T. (1999). Transferrin stimulates iron absorption, exocytosis and secretion in cultured intestinal cells. Annual Journal of Physiology, 276, C1085-C1090.
18. West, D.W. (1986). Structure and function of the phosphorylated residues of casein. Journal of Dairy Research, 53, 333-352.
19. WHO (2002). Micronutrient deficiencies. Battling iron deficiency anaemia. Statement on how widespread iron deficiency anaemia is; available at: http:/www.who.int/nut/ida.htm.