Effects of tyrosine phosphorylation of cortactin on podosome formation in A7r5 vascular smooth muscle cells

American Journal of Physiology - Cell Physiology

Volumn 290, Issue 2, 2006, Pages

  Zhou, Shutang ^a   Webb, Bradley A ^a   Eves, Robert ^a   Mak, Alan S ^a  

^a QUEEN S UNIVERSITY   (Canada)

Author keywords

Actin cytoskeleton; Protein kinase C; Src

Indexed keywords

2,3 DIHYDRO 2 OXO 3 (4,5,6,7 TETRAHYDRO 1H INDOL 2 YLMETHYLENE) 1H INDOLE 5 SULFONIC ACID DIMETHYLAMIDE; CORTACTIN; MUTANT PROTEIN; PHORBOL DIBUTYRATE; PHORBOL ESTER; PROTEIN KINASE C ALPHA; PROTEIN KINASE C INHIBITOR; SMALL INTERFERING RNA; TYROSINE; BISINDOLYLMALEIMIDE; CARCINOGEN; INDOLE DERIVATIVE; MALEIMIDE DERIVATIVE; PROTEIN TYROSINE KINASE; SULFONAMIDE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL STRUCTURE; CONTROLLED STUDY; ENZYME INHIBITION; GENETIC TRANSFECTION; MUTATION; NONHUMAN; ONCOGENE SRC; PODOSOME; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; RAT; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE; ANIMAL; CELL LINE; CELL SHAPE; CELL SURFACE; CYTOLOGY; DRUG ANTAGONISM; FLUORESCENCE MICROSCOPY; GENETICS; METABOLISM; PHOSPHORYLATION;

ANIMALIA;

ANIMALS; CARCINOGENS; CELL LINE; CELL SHAPE; CELL SURFACE EXTENSIONS; CORTACTIN; INDOLES; MALEIMIDES; MICROSCOPY, FLUORESCENCE; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PHORBOL 12,13-DIBUTYRATE; PHOSPHORYLATION; PROTEIN KINASE C-ALPHA; RATS; RNA, SMALL INTERFERING; SRC-FAMILY KINASES; SULFONAMIDES; TYROSINE;

EID: 33644860573     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00350.2005     Document Type: Article

References (46)

1. Amato PA, Unanue ER, and Taylor DL. Distribution of actin in spreading macrophages: a comparative study on living and fixed cells. J Cell Biol 96: 750-761, 1983.
2. Brandt D, Gimona M, Hillmann M, Haller H, and Mischak H. Protein kinase C induces actin reorganization via a Src- and Rho-dependent pathway. J Biol Chem 277: 20903-20910, 2002.
3. Brandt DT, Goerke A, Heuer M, Gimona M, Leitges M, Kremmer E, Lammers R, Haller H, and Mischak H. Protein kinase Cδ induces Src kinase activity via activation of the protein tyrosine phosphatase PTPα. J Biol Chem 278: 34073-34078, 2003.
4. Bruce-Staskal PJ and Bouton AH. PKC-dependent activation of FAK and src induces tyrosine phosphorylation of Cas and formation of Cas-Crk complexes. Exp Cell Res 264: 296-306, 2001.
5. Burgstaller G and Gimona M. Actin cytoskeleton remodelling via local inhibition of contractility at discrete microdomains. J Cell Sci 117: 223-231, 2004.
6. Burns S, Thrasher AJ, Blundell MP, Machesky L, and Jones GE. Configuration of human dendritic cell cytoskeleton by Rho GTPases, the WAS protein, and differentiation. Blood 98: 1142-1149, 2001.
7. Craig AW, Zirngibl R, Williams K, Cole LA, and Greer PA. Mice devoid of fer protein-tyrosine kinase activity are viable and fertile but display reduced cortactin phosphorylation. Mol Cell Biol 21: 603-613, 2001.
8. Daly RJ. Cortactin signalling and dynamic actin networks. Biochem J 382: 13-25, 2004.
9. Destaing O, Saltel F, Geminard JC, Jurdic P, and Bard F. Podosomes display actin turnover and dynamic self-organization in osteoclasts expressing actin-green fluorescent protein. Mol Biol Cell 14: 407-416, 2003.
10. Dudek SM, Birukov KG, Zhan X, and Garcia JG. Novel interaction of cortactin with endothelial cell myosin light chain kinase. Biochem Biophys Res Commun 298: 511-519, 2002.
11. Dudek SM, Jacobson JR, Chiang ET, Birukov KG, Wang P, Zhan X, and Garcia JG. Pulmonary endothelial cell barrier enhancement by sphingosine 1-phosphate: roles for cortactin and myosin light chain kinase. J Biol Chem 279: 24692-24700, 2004.
12. Fan L, Ciano-Oliveira C, Weed SA, Craig AW, Greer PA, Rotstein OD, and Kapus A. Actin depolymerization-induced tyrosine phosphorylation of cortactin: the role of Fer kinase. Biochem J 380: 581-591, 2004.
13. Fultz ME, Li C, Geng W, and Wright GL. Remodeling of the actin cytoskeleton in the contracting A7r5 smooth muscle cell. J Muscle Res Cell Motil 21: 775-787, 2000.
14. Gallet C, Rosa JP, Habib A, Lebret M, Levy-Toledano S, and Maclouf J. Tyrosine phosphorylation of cortactin associated with Syk accompanies thromboxane analogue-induced platelet shape change. J Biol Chem 274: 23610-23616, 1999.
15. Gatesman A, Walker VG, Baisden JM, Weed SA, and Flynn DC. Protein kinase Cα activates c-Src and induces podosome formation via AFAP-110. Mol Cell Biol 24: 7578-7597, 2004.
16. Gimona M, Kaverina I, Resch GP, Vignal E, and Burgstaller G. Calponin repeats regulate actin filament stability and formation of podosomes in smooth muscle cells. Mol Biol Cell 14: 2482-2491, 2003.
17. Hai CM, Hahne P, Harrington EO, and Gimona M. Conventional protein kinase C mediates phorbol-dibutyrate-induced cytoskeletal remodeling in A7r5 smooth muscle cells. Exp Cell Res 280: 64-74, 2002.
18. Head JA, Jiang D, Li M, Zorn LJ, Schaefer EM, Parsons JT, and Weed SA. Cortactin tyrosine phosphorylation requires Rac1 activity and association with the cortical actin cytoskeleton. Mol Biol Cell 14: 3216-3229, 2003.
19. Huang C, Liu J, Haudenschild CC, and Zhan X. The role of tyrosine phosphorylation of cortactin in the locomotion of endothelial cells. J Biol Chem 273: 25770-25776, 1998.
20. Huang C, Ni Y, Wang T, Gao Y, Haudenschild CC, and Zhan X. Down-regulation of the filamentous actin cross-linking activity of cortactin by Src-mediated tyrosine phosphorylation. J Biol Chem 272: 13911-13915, 1997.
21. Huang J, Asawa T, Takato T, and Sakai R. Cooperative roles of Fyn and cortactin in cell migration of metastatic murine melanoma. J Biol Chem 278: 48367-48376, 2003.
22. Hung W and Elliott B. Co-operative effect of c-Src tyrosine kinase and Stat3 in activation of hepatocyte growth factor expression in mammary carcinoma cells. J Biol Chem 276: 12395-12403, 2001.
23. Kapus A, Di Ciano C, Sun J, Zhan X, Kim L, Wong TW, and Rotstein OD. Cell volume-dependent phosphorylation of proteins of the cortical cytoskeleton and cell-cell contact sites. The role of Fyn and FER kinases. J Biol Chem 275: 32289-32298, 2000.
24. Kaverina I, Stradal TE, and Gimona M. Podosome formation in cultured A7r5 vascular smooth muscle cells requires Arp2/3-dependent de-novo actin polymerization at discrete microdomains. J Cell Sci 116: 4915-4924, 2003.
25. Kimes BW and Brandt BL. Characterization of two putative smooth muscle cell lines from rat thoracic aorta. Exp Cell Res 98: 349-366, 1976.
26. Linder S and Aepfelbacher M. Podosomes: adhesion hot-spots of invasive cells. Trends Cell Biol 13: 376-385, 2003.
27. Lopez I, Duprez V, Melle J, Dreyfus F, Levy-Toledano S, and Fontenay-Roupie M. Thrombopoietin stimulates cortactin translocation to the cytoskeleton independently of tyrosine phosphorylation. Biochem J 356: 875-881, 2001.
28. Marchisio PC, Cirillo D, Naldini L, Primavera MV, Teti A, and Zambonin-Zallone A. Cell-substratum interaction of cultured avian osteoclasts is mediated by specific adhesion structures. J Cell Biol 99: 1696-1705, 1984.
29. Martinez-Quiles N, Ho HY, Kirschner MW, Ramesh N, and Geha RS. Erk/Src phosphorylation of cortactin acts as a switch on-switch off mechanism that controls its ability to activate N-WASP. Mol Cell Biol 24: 5269-5280, 2004.
30. Mizutani K, Miki H, He H, Maruta H, and Takenawa T. Essential role of neural Wiskott-Aldrich syndrome protein in podosome formation and degradation of extracellular matrix in src-transformed fibroblasts. Cancer Res 62: 669-674, 2002.
31. Moreau V, Tatin F, Varon C, and Genot E. Actin can reorganize into podosomes in aortic endothelial cells, a process controlled by Cdc42 and RhoA. Mol Cell Biol 23: 6809-6822, 2003.
32. Nitsch L, Gionti E, Cancedda R, and Marchisio PC. The podosomes of Rous sarcoma virus transformed chondrocytes show a peculiar ultrastructural organization. Cell Biol Int Rep 13: 919-926, 1989.
33. Okamura H and Resh MD. p80/85 cortactin associates with the Src SH2 domain and colocalizes with v-Src in transformed cells. J Biol Chem 270: 26613-26618, 1995.
34. Pfaff M and Jurdic P. Podosomes in osteoclast-like cells: structural analysis and cooperative roles of paxillin, proline-rich tyrosine kinase 2 (Pyk2) and integrin αVβ3. J Cell Sci 114: 2775-2786, 2001.
35. Purchio AF, Shoyab M, and Gentry LE. Site-specific increased phosphorylation of pp60v-src after treatment of RSV-transformed cells with a tumor promoter. Science 229: 1393-1395, 1985.
36. Qureshi SA, Joseph CK, Rim M, Maroney A, and Foster DA. v-Src activates both protein kinase C-dependent and independent signaling pathways in murine fibroblasts. Oncogene 6: 995-999, 1991.
37. Seals DF, Azucena EF, Pass I, Tesfay L, Gordon R, Woodrow M, Resau JH, and Courtneidge SA. The adaptor protein Tks5/Fish is required for podosome formation and function, and for the protease-driven invasion of cancer cells. Cancer Cell 7: 155-165, 2005.
38. Tarone G, Cirillo D, Giancotti FG, Comoglio PM, and Marchisio PC. Rous sarcoma virus-transformed fibroblasts adhere primarily at discrete protrusions of the ventral membrane called podosomes. Exp Cell Res 159: 141-157, 1985.
39. Uruno T, Liu J, Zhang P, Fan Y, Egile C, Li R, Mueller SC, and Zhan X. Activation of Arp2/3 complex-mediated actin polymerization by cortactin. Nat Cell Biol 3: 259-266, 2001.
40. Vidal C, Geny B, Melle J, Jandrot-Perrus M, and Fontenay-Roupie M. Cdc42/Rac1-dependent activation of the p21-activated kinase (PAK) regulates human platelet lamellipodia spreading: implication of the corticalactin binding protein cortactin. Blood 100: 4462-4469, 2002.
41. Weaver AM, Karginov AV, Kinley AW, Weed SA, Li Y, Parsons JT, and Cooper JA. Cortactin promotes and stabilizes Arp2/3-induced actin filament network formation. Curr Biol 11: 370-374, 2001.
42. Webb BA, Eves R, Crawley SW, Zhou S, Cote GP, and Mak AS. PAK1 induces podosome formation in A7r5 vascular smooth muscle cells in a PAK-interacting exchange factor-dependent manner. Am J Physiol Cell Physiol 289: C898-C907, 2005.
43. Weed SA and Parsons JT. Cortactin: coupling membrane dynamics to cortical actin assembly. Oncogene 20: 6418-6434, 2001.
44. Weed SA, Karginov AV, Schafer DA, Weaver AM, Kinley AW, Cooper JA, and Parsons JT. Cortactin localization to sites of actin assembly in lamellipodia requires interactions with F-actin and the Arp2/3 complex. J Cell Biol 151: 29-40, 2000.
45. Wu H and Parsons JT. Cortactin, an 80/85-kilodalton pp60src substrate, is a filamentous actin-binding protein enriched in the cell cortex. J Cell Biol 120: 1417-1426, 1993.
46. Wu H, Reynolds AB, Kanner SB, Vines RR, and Parsons JT. Identification and characterization of a novel cytoskeleton-associated pp60src substrate. Mol Cell Biol 11: 5113-5124, 1991.