-
1
-
-
0031127305
-
Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase B alpha
-
ALESSI, D. R., S. R. JAMES, C. P. DOWNES, et al. Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase B alpha. Curr. Biol. 1: 261-266, 1997.
-
(1997)
Curr. Biol.
, vol.1
, pp. 261-266
-
-
Alessi, D.R.1
James, S.R.2
Downes, C.P.3
-
2
-
-
0022598369
-
Quantitative structural analysis of the myocardium during physiologic growth and induced cardiac hypertrophy
-
ANVERSA, P., R. RICCI, and G. OLIVETTI. Quantitative structural analysis of the myocardium during physiologic growth and induced cardiac hypertrophy. J. Am. Coll. Cardiol. 7:1140-1146, 1986.
-
(1986)
J. Am. Coll. Cardiol.
, vol.7
, pp. 1140-1146
-
-
Anversa, P.1
Ricci, R.2
Olivetti, G.3
-
3
-
-
0030807080
-
Rapamycin inhibits alpha 1-adrenergic receptor-stimulated cardiac myocyte hypertrophy but not activation of hypertrophy-associated genes. Evidence for involvement of p70S6 kinase
-
BOLUYT, M. O., J. S. ZHENG, A. YOUNES, et al. Rapamycin inhibits alpha 1-adrenergic receptor-stimulated cardiac myocyte hypertrophy but not activation of hypertrophy-associated genes. Evidence for involvement of p70S6 kinase. Circ. Res. 81:176-186, 1997.
-
(1997)
Circ. Res.
, vol.81
, pp. 176-186
-
-
Boluyt, M.O.1
Zheng, J.S.2
Younes, A.3
-
4
-
-
0035910603
-
The dual-specificity phosphatase MKP-1 limits the cardiac hypertrophic response in vitro and in vivo
-
BUENO, O. F., L. J. DE WINDT, H. W. LIM, et al. The dual-specificity phosphatase MKP-1 limits the cardiac hypertrophic response in vitro and in vivo. Circ. Res. 88:88-96, 2001.
-
(2001)
Circ. Res.
, vol.88
, pp. 88-96
-
-
Bueno, O.F.1
De Windt, L.J.2
Lim, H.W.3
-
5
-
-
0034383952
-
The MEK1-ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice
-
BUENO, O. F., L. J. DE WINDT, K. M. TYMITZ, et al. The MEK1-ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice. EMBO J. 19:6341-6350, 2000.
-
(2000)
EMBO J.
, vol.19
, pp. 6341-6350
-
-
Bueno, O.F.1
De Windt, L.J.2
Tymitz, K.M.3
-
6
-
-
0034916532
-
TGF-α1 and prepro-ANP mRNAs are differentially regulated in exercise-induced cardiac hypertrophy
-
CALDERONE, A., R. J. L. MURPHY, J. LAVOIE, F. COLOMBO, and L. BELIVEAU. TGF-α1 and prepro-ANP mRNAs are differentially regulated in exercise-induced cardiac hypertrophy. J. Appl. Physiol. 91:771-776, 2001.
-
(2001)
J. Appl. Physiol.
, vol.91
, pp. 771-776
-
-
Calderone, A.1
Murphy, R.J.L.2
Lavoie, J.3
Colombo, F.4
Beliveau, L.5
-
7
-
-
0028788935
-
The 70 kD S6 kinase: Regulation of a kinase with multiple roles in mitogenic signaling
-
CHOU, M. M., and J. BLENIS. The 70 kD S6 kinase: regulation of a kinase with multiple roles in mitogenic signaling. Curr. Opin. Cell. Biol. 7:806-814, 1995.
-
(1995)
Curr. Opin. Cell. Biol.
, vol.7
, pp. 806-814
-
-
Chou, M.M.1
Blenis, J.2
-
8
-
-
0037401776
-
β-adrenergic receptor-mediated DNA synthesis in cardiac fibroblasts proceeds via a phosphatidylinositol 3-kinase dependent pathway refractory to the antiproliferative action of cyclic AMP
-
COLOMBO, F., H. GOSSELIN, V. EL-HELOU, and A. CALDERONE. β-adrenergic receptor-mediated DNA synthesis in cardiac fibroblasts proceeds via a phosphatidylinositol 3-kinase dependent pathway refractory to the antiproliferative action of cyclic AMP. J. Cell. Physiol. 195:322-330, 2003.
-
(2003)
J. Cell. Physiol.
, vol.195
, pp. 322-330
-
-
Colombo, F.1
Gosselin, H.2
El-Helou, V.3
Calderone, A.4
-
9
-
-
0037125980
-
Akt induces enhanced myocardial contractility and cell size in vivo in transgenic mice
-
CONDORELLI, G., A. DRUSCO, G. STASSI, et al. Akt induces enhanced myocardial contractility and cell size in vivo in transgenic mice. Proc. Natl. Acad. Sci. USA 99:12333-12338, 2002.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 12333-12338
-
-
Condorelli, G.1
Drusco, A.2
Stassi, G.3
-
10
-
-
14644414790
-
Protein kinase cascades in the regulation of cardiac hypertrophy
-
DORN, G. W., and T. FORCE. Protein kinase cascades in the regulation of cardiac hypertrophy. J. Clin. Invest. 115:527-537, 2005.
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 527-537
-
-
Dorn, G.W.1
Force, T.2
-
11
-
-
0029780935
-
Angiotensin receptor 1 blockade does not prevent physiological cardiac hypertrophy in the adult rat
-
GEENEN, D. L., A. MALHOTRA, and P. M. BUTTRICK. Angiotensin receptor 1 blockade does not prevent physiological cardiac hypertrophy in the adult rat. J. Appl. Physiol. 81:816-821, 1996.
-
(1996)
J. Appl. Physiol.
, vol.81
, pp. 816-821
-
-
Geenen, D.L.1
Malhotra, A.2
Buttrick, P.M.3
-
12
-
-
0026693383
-
Structural remodelling of cardiac myocytes in patients with ischemic cardiomyopathy
-
GERDES, A. M., S. E. KELLERMAN, J. A. MOORE, et al. Structural remodelling of cardiac myocytes in patients with ischemic cardiomyopathy. Circulation 86:426-430, 1992.
-
(1992)
Circulation
, vol.86
, pp. 426-430
-
-
Gerdes, A.M.1
Kellerman, S.E.2
Moore, J.A.3
-
13
-
-
0016681078
-
Wall stress and patterns of cardiac hypertrophy in the human left ventricle
-
GROSSMAN, W., D. JONES, and L. P. MCLAURIN. Wall stress and patterns of cardiac hypertrophy in the human left ventricle. J. Clin. Invest. 56:56-64, 1974.
-
(1974)
J. Clin. Invest.
, vol.56
, pp. 56-64
-
-
Grossman, W.1
Jones, D.2
McLaurin, L.P.3
-
14
-
-
0032169224
-
Regional myocyte hypertrophy parallels regional myocardial dysfunction during post-infarct remodelling
-
KRAMER, C. M., W. J. ROGERS, C. S. PARK, et al. Regional myocyte hypertrophy parallels regional myocardial dysfunction during post-infarct remodelling. J. Mol. Cell. Cardiol. 30: 1773-1778, 1998.
-
(1998)
J. Mol. Cell. Cardiol.
, vol.30
, pp. 1773-1778
-
-
Kramer, C.M.1
Rogers, W.J.2
Park, C.S.3
-
15
-
-
2342533184
-
Exercise training attenuated the PKB and GSK-3 dephosphorylation in the myocardium of ZDF rats
-
LAJOIE, C., F. TRUDEAU, N. LAVOIE, et al. Exercise training attenuated the PKB and GSK-3 dephosphorylation in the myocardium of ZDF rats. J. Appl. Physiol. 96:1606-1612, 2004.
-
(2004)
J. Appl. Physiol.
, vol.96
, pp. 1606-1612
-
-
Lajoie, C.1
Trudeau, F.2
Lavoie, N.3
-
16
-
-
0035654625
-
Effects of streptozocin diabetes and diabetes treatment by islet transplantation on in vivo insulin signaling in rat heart
-
LAVIOLA, L., G. BELSANTI, A. M. DAVALLI, et al. Effects of streptozocin diabetes and diabetes treatment by islet transplantation on in vivo insulin signaling in rat heart. Diabetes 50:2709-2720, 2001.
-
(2001)
Diabetes
, vol.50
, pp. 2709-2720
-
-
Laviola, L.1
Belsanti, G.2
Davalli, A.M.3
-
17
-
-
0032544704
-
Differential activation of p70 and p85 S6 kinase isoforms during cardiac hypertrophy in the adult mammal
-
LASER, M., V. S. KASI, M. HAMAWAKI, G. I. V. COOPER, C. KERR, and D. KUPPUSWAMY. Differential activation of p70 and p85 S6 kinase isoforms during cardiac hypertrophy in the adult mammal. J. Biol. Chem. 273:24610-24619, 1998.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 24610-24619
-
-
Laser, M.1
Kasi, V.S.2
Hamawaki, M.3
Cooper, G.I.V.4
Kerr, C.5
Kuppuswamy, D.6
-
18
-
-
0021668106
-
Correlation of myosin isoenzyme alterations with myocardial function in physiologic and pathologic hypertrophy
-
MALHOTRA, A., T. F. SCHAIBLE, J. CAPASSO, and J. SCHEUER. Correlation of myosin isoenzyme alterations with myocardial function in physiologic and pathologic hypertrophy. Eur. Heart. J. 5:61-67, 1984.
-
(1984)
Eur. Heart. J.
, vol.5
, pp. 61-67
-
-
Malhotra, A.1
Schaible, T.F.2
Capasso, J.3
Scheuer, J.4
-
19
-
-
0037151104
-
Phenotypic spectrum caused by transgenic overexpression of activated AKT in the heart
-
MATSUI, T., L. Li, J. C. Wu, S. A. COOK, et al. Phenotypic spectrum caused by transgenic overexpression of activated AKT in the heart. J. Biol. Chem. 277:22896-22901, 2002.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 22896-22901
-
-
Matsui, T.1
Li, L.2
Wu, J.C.3
Cook, S.A.4
-
20
-
-
0142027759
-
Phosphoinositide 3-kinase (p110α) plays a critical role for the induction of physiological, but not pathological, cardiac hypertrophy
-
MC MULLEN, J. R., T. SHIOI, L. ZHANG, et al. Phosphoinositide 3-kinase (p110α) plays a critical role for the induction of physiological, but not pathological, cardiac hypertrophy. Proc. Natl. Aca. Sci. USA 100:12355-12360, 2003.
-
(2003)
Proc. Natl. Aca. Sci. USA
, vol.100
, pp. 12355-12360
-
-
Mc Mullen, J.R.1
Shioi, T.2
Zhang, L.3
-
21
-
-
0027212732
-
Chronic exercise alters contractility and morphology of isolated cardiac myocytes
-
MOORE, R. L., T. I. R. MUSCH, V. YELAMARTY, et al. Chronic exercise alters contractility and morphology of isolated cardiac myocytes. Am. J. Physiol. (Cell Physiol) 264:C1180-C1189, 1993.
-
(1993)
Am. J. Physiol. (Cell Physiol)
, vol.264
-
-
Moore, R.L.1
Musch, T.I.R.2
Yelamarty, V.3
-
22
-
-
0034640299
-
The AKT/glycogen synthase kinase 3β pathway regulates transcription of atrial natriuretic factor induced by β-adrenergic receptor stimulation in cardiac myocytes
-
MORISCO, C., D. ZEBROWSKI, G. CONDORELLI, P. TSICHLIS, S. F. VATNER, and J. SADOSHIMA. The AKT/glycogen synthase kinase 3β pathway regulates transcription of atrial natriuretic factor induced by β-adrenergic receptor stimulation in cardiac myocytes. J. Biol. Chem. 275:14466-14475, 2000.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 14466-14475
-
-
Morisco, C.1
Zebrowski, D.2
Condorelli, G.3
Tsichlis, P.4
Vatner, S.F.5
Sadoshima, J.6
-
23
-
-
0038630437
-
ATI receptor antagonist therapy preferentially ameliorated right ventricular function and phenotype during the early phase of remodelling post MI
-
NGUYEN, Q. T., F. COLOMBO, R. CLEMENT, H. GOSSELIN, J. L. ROULEAU, and A. CALDERONE. ATI receptor antagonist therapy preferentially ameliorated right ventricular function and phenotype during the early phase of remodelling post MI. Br. J. Pharmacol. 138:1485-1494, 2003.
-
(2003)
Br. J. Pharmacol.
, vol.138
, pp. 1485-1494
-
-
Nguyen, Q.T.1
Colombo, F.2
Clement, R.3
Gosselin, H.4
Rouleau, J.L.5
Calderone, A.6
-
24
-
-
0035355360
-
Activated MEK5 induces serial assembly of sarcomeres and eccentric cardiac hypertrophy
-
NICOL, R. L., N. FREY, G. PEARSON, M. COBB, J. RICHARDSON, and E. N. OLSON. Activated MEK5 induces serial assembly of sarcomeres and eccentric cardiac hypertrophy. EMBO J. 20: 2757-2767, 2001.
-
(2001)
EMBO J.
, vol.20
, pp. 2757-2767
-
-
Nicol, R.L.1
Frey, N.2
Pearson, G.3
Cobb, M.4
Richardson, J.5
Olson, E.N.6
-
25
-
-
0032516498
-
Cytokine gene expression after myocardial infarction in rat hearts
-
ONO, K., A. MATSUMORI, T. SHIOI, Y. FURUKAWA, and S. SASAYAMA. Cytokine gene expression after myocardial infarction in rat hearts. Circulation 98:149-156, 1998.
-
(1998)
Circulation
, vol.98
, pp. 149-156
-
-
Ono, K.1
Matsumori, A.2
Shioi, T.3
Furukawa, Y.4
Sasayama, S.5
-
26
-
-
0028802451
-
The principal target of rapamycin-induced p70s6k inactivation is a novel phosphorylation site within a conserved hydrophobic domain
-
PEARSON, R. B., P. B. DENNIS, J. W. HAN, et al. The principal target of rapamycin-induced p70s6k inactivation is a novel phosphorylation site within a conserved hydrophobic domain. EMBO J. 14:5279-5287, 1995.
-
(1995)
EMBO J.
, vol.14
, pp. 5279-5287
-
-
Pearson, R.B.1
Dennis, P.B.2
Han, J.W.3
-
27
-
-
0028906021
-
Angiotensin-converting enzyme inhibition and ventricular remodeling after myocardial infarction
-
PFEFFER, J. M., T. A. FISCHER, and M. A. PFEFFER, Angiotensin-converting enzyme inhibition and ventricular remodeling after myocardial infarction. Ann. Rev. Physiol. 37:805-828, 1995.
-
(1995)
Ann. Rev. Physiol.
, vol.37
, pp. 805-828
-
-
Pfeffer, J.M.1
Fischer, T.A.2
Pfeffer, M.A.3
-
28
-
-
0030740005
-
The modular phosphorylation and activation of p70s6K
-
PULLEN, N., and G. THOMAS. The modular phosphorylation and activation of p70s6K. FEBS Lett. 410:78-82, 1997.
-
(1997)
FEBS Lett.
, vol.410
, pp. 78-82
-
-
Pullen, N.1
Thomas, G.2
-
29
-
-
0034607914
-
Ceramide inhibits protein kinase B/Akt by promoting dephosphorylation of serine 473
-
SCHUBERT, K. M., M. P. SCHEID, and V. DURONIO. Ceramide inhibits protein kinase B/Akt by promoting dephosphorylation of serine 473. J. Biol. Chem. 275:13330-13335, 2000.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 13330-13335
-
-
Schubert, K.M.1
Scheid, M.P.2
Duronio, V.3
-
30
-
-
0034213075
-
The conserved phosphoinositide 3-kinase pathway determines heart size in mice
-
SHIOI, T., P. M. KANG, P. S. DOUGLAS, et al. The conserved phosphoinositide 3-kinase pathway determines heart size in mice. EMBO J. 19:2537-2548, 2000.
-
(2000)
EMBO J.
, vol.19
, pp. 2537-2548
-
-
Shioi, T.1
Kang, P.M.2
Douglas, P.S.3
-
31
-
-
0037382861
-
Rapamycin attenuates load-induced cardiac hypertrophy in mice
-
SHIOI, T., J. R. MCMULLEN, O. TARNAVSKI, et al. Rapamycin attenuates load-induced cardiac hypertrophy in mice. Circulation 107:1664-1670, 2003.
-
(2003)
Circulation
, vol.107
, pp. 1664-1670
-
-
Shioi, T.1
McMullen, J.R.2
Tarnavski, O.3
-
32
-
-
0030799706
-
Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B
-
STOKOE, D., L. R. STEPHENS, T. COPELAND, et al. Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B. Science 277:567-570, 1992.
-
(1992)
Science
, vol.277
, pp. 567-570
-
-
Stokoe, D.1
Stephens, L.R.2
Copeland, T.3
-
33
-
-
0141594871
-
Protein kinase C promotes apoptosis in LNCaP prostate cancer cells through activation of p38 MAPK and inhibition of the Akt survival pathway
-
TANAKA, Y., M. V. GAVRIELIDES, Y. MITSUUCHI, T. FUJII, and M. G. KAZANIETZ. Protein kinase C promotes apoptosis in LNCaP prostate cancer cells through activation of p38 MAPK and inhibition of the Akt survival pathway. J. Biol. Chem. 278: 33753-33762, 2003.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 33753-33762
-
-
Tanaka, Y.1
Gavrielides, M.V.2
Mitsuuchi, Y.3
Fujii, T.4
Kazanietz, M.G.5
|