A variant in the CD209 promoter is associated with severity of dengue disease

Nature Genetics

Volumn 37, Issue 5, 2005, Pages 507-513

  Sakuntabhai, Anavaj ^a,b   Turbpaiboon, Chairat ^a,c   Casadémont, Isabelle ^a   Chuansumrit, Ampaiwan ^b   Lowhnoo, Tassanee ^a,b,d   Kajaste Rudnitski, Anna ^a   Kalayanarooj, Sita Mint ^a,e   Tangnararatchakit, Kanchana ^b   Tangthawornchaikul, Nattaya ^f   Vasanawathana, Sirijit ^g   Chaiyaratana, Wathanee ^b   Yenchitsomanus, Pa Thai ^e,f   Suriyaphol, Prapat ^e   Avirutnan, Panisadee ^e   Chokephaibulkit, Kulkanya ^e   Matsuda, Fumihiko ^d   Yoksan, Sutee ^c   Jacob, Yves ^a   Lathrop, G Mark ^d   Malasit, Prida ^e,f   Desprès, Philippe ^a   Julier, Cécile ^a   more..

^a INSTITUT PASTEUR   (France)

^b MAHIDOL UNIVERSITY   (Thailand)

^c MAHIDOL UNIVERSITY   (Thailand)

^d CENTRE NATIONAL DE GÉNOTYPAGE   (France)

^e MAHIDOL UNIVERSITY   (Thailand)

^f NATIONAL SCIENCE AND TECHNOLOGY DEVELOPMENT AGENCY   (Thailand)

^g KHON KAEN HOSPITAL   (Thailand)

Author keywords

[No Author keywords available]

Indexed keywords

CD209 ANTIGEN; RECEPTOR; TRANSCRIPTION FACTOR SP1;

ADOLESCENT; ARTICLE; BINDING SITE; CD209 GENE; CHILD; CONTROLLED STUDY; DENDRITIC CELL; DENGUE; DENGUE VIRUS; DISEASE SEVERITY; FEMALE; GENE; GENE FREQUENCY; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; HUMAN; HUMAN CELL; INFECTION RISK; MAJOR CLINICAL STUDY; MALE; PATHOGENESIS; PRIORITY JOURNAL; PROMOTER REGION; THAILAND; VIRUS ADSORPTION;

CELL ADHESION MOLECULES; DENGUE; HUMANS; LECTINS, C-TYPE; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS); RECEPTORS, CELL SURFACE; SEVERITY OF ILLNESS INDEX;

EID: 20944450979     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/ng1550     Document Type: Article

References (30)

1. Tassaneetrithep, B. et al. DC-SIGN (CD209) mediates dengue virus infection of human dendritic cells. J. Exp. Med. 197, 823-829 (2003).
2. Navarro-Sanchez, E. et al. Dendritic-cell-specific ICAMS-grabbing non-integrin is essential for the productive infection of human dendritic cells by mosquito-cell-derived dengue viruses. EMBO Rep. 4, 1-6 (2003).
3. World Health Organization. Dengue Haemorrhagic Fever: Diagnosis, Treatment, Prevention and Control (World Health Organization, Geneva, 1997).
4. Burke, D.S., Nisalak, A., Johnson, D.E. & Scott, R.M. A prospective study of dengue infections in Bangkok. Am. J. Trop. Med. Hyg. 38, 172-180 (1988).
5. Halstead, S.B. Pathogenesis of dengue: challenges to molecular biology. Science 239, 476-481 (1988).
6. Liu, W. et al. Characterization of a novel C-type lectin-like gene, LSECtin: demonstration of carbohydrate binding and expression in sinusoidal endothelial cells of liver and lymph node. J. Biol. Chem. 279, 18748-18758 (2004).
7. Liu, H., Yu, W., Liou, L.Y. & Rice, A.P. Isolation and characterization of the human DC-SIGN and DC-SIGNR promoters. Gene 313, 149-159 (2003).
8. Grant, S.F. et al. Reduced bone density and osteoporosis associated with a polymorphic Sp1 binding site in the collagen type I alpha 1 gene. Nat. Genet. 14, 203-205 (1996).
9. Mann, V. et al. ACOL1A1 Sp1 binding site polymorphism predisposes to osteoporotic fracture by affecting bone density and quality. J. Clin. Invest. 107, 899-907 (2001).
10. Harendza, S. et al. Linked common polymorphisms in the gelatinase a promoter are associated with diminished transcriptional response to estrogen and genetic fitness. J. Biol. Chem. 278, 20490-20499 (2003).
11. Sibley, K. et al. Functional FAS promoter polymorphisms are associated with increased risk of acute myeloid leukemia. Cancer Res. 63, 4327-4330 (2003).
12. Rothman, A.L. Immunology and immunopathogenesis of dengue disease. Adv. Virus Res. 60, 397-419 (2003).
13. Mongkolsapaya, J. et al. Original antigenic sin and apoptosis in the pathogenesis of dengue hemorrhagic fever. Nat. Med. 9, 921-927 (2003).
14. Vaughn, D.W. et al. Dengue viremia titer, antibody response pattern, and virus serotype correlate with disease severity. J. Infect. Dis. 181, 2-9 (2000).
15. Loke, H. et al. Strong HLA class I-restricted T cell responses in dengue hemorrhagic fever: a double-edged sword? J. Infect. Dis. 184, 1369-1373 (2001).
16. Chiewsilp, P., Scott, R.M. & Bhamarapravati, N. Histocompatibility antigens and dengue hemorrhagic fever. Am. J. Trop. Med. Hyg. 30, 1100-1105 (1981).
17. Paradoa Perez, M.L., Trujillo, Y. & Basanta, P. Association of dengue hemorrhagic fever with the HLA system. Haematologia (Budap.) 20, 83-87 (1987).
18. Stephens, H.A. et al. HLA-A and -B allele associations with secondary dengue virus infections correlate with disease severity and the infecting viral serotype in ethnic Thais. Tissue Antigens 60, 309-318 (2002).
19. Loke, H. et al. Susceptibility to dengue hemorrhagic fever in Vietnam: evidence of an association with variation in the vitamin d receptor and Fc gamma receptor IIa genes. Am. J. Trop. Med. Hyg. 67, 102-106 (2002).
20. Fernandez-Mestre, M.T., Gendzekhadze, K., Rivas-Vetencourt, P. & Layrisse, Z. TNF-alpha-308A allele, a possible severity risk factor of hemorrhagic manifestation in dengue fever patients. Tissue Antigens 64, 469-472 (2004).
21. Klimstra, W.B., Nangle, E.M., Smith, M.S., Yurochko, A.D. & Ryman, K.D. DC-SIGN and L-SIGN can act as attachment receptors for alphaviruses and distinguish between mosquito cell- and mammalian cell-derived viruses. J. Virol. 77, 12022-12032 (2003).
22. van Kooyk, Y., Appelmelk, B. & Geijtenbeek, T.B. A fatal attraction: Mycobacterium tuberculosis and HIV-1 target DC-SIGN to escape immune surveillance. Trends Mol. Med. 9, 153-159 (2003).
23. Halary, F. et al. Human cytomegalovirus binding to DC-SIGN is required for dendritic cell infection and target cell trans-infection. Immunity 17, 653-664 (2002).
24. Tailleux, L. et al. DC-SIGN is the major Mycobacterium tuberculosis receptor on human dendritic cells. J. Exp. Med. 197, 121-127 (2003).
25. Yang, Z.Y. et al. pH-dependent entry of severe acute respiratory syndrome coronavirus is mediated by the spike glycoprotein and enhanced by dendritic cell transfer through DC-SIGN. J. Virol. 78, 5642-5650 (2004).
26. Martin, M.P. et al. Association of DC-SIGN promoter polymorphism with increased risk for parenteral, but not mucosal, acquisition of human immunodeficiency virus type 1 infection. J. Virol. 78, 14053-14056 (2004).
27. Innis, B.L. et al. An enzyme-linked immunosorbent assay to characterize dengue infections where dengue and Japanese encephalitis co-circulate. Am. J. Trop. Med. Hyg. 40, 418-427 (1989).
28. Takahashi, M., Matsuda, F., Margetic, N. & Lathrop, M. Automated identification of single nucleotide polymorphisms from sequencing data. J. Bioinform. Comput. Biol. 1, 253-265 (2003).
29. Mummidi, S. et al. Extensive repertoire of membrane-bound and soluble dendritic cell-specific ICAM-3-grabbing nonintegrin 1 (DC-SIGN1) and DC-SIGN2 isoforms. Inter-individual variation in expression of DC-SIGN transcripts. J. Biol. Chem. 276, 33196-33212 (2001).
30. Abecasis, G.R. & Cookson, W.O. GOLD-graphical overview of linkage disequilibrium. Bioinformatics 16, 182-183 (2000).