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Volumn 26, Issue 2, 2006, Pages 173-181

The role of aldosterone in renal sodium transport

Author keywords

Aldosterone; ENaC; NCC; SGK1; Sodium transport; WNK

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ADENOSINE TRIPHOSPHATASE (POTASSIUM); ALDOSTERONE; COTRANSPORTER; MINERALOCORTICOID; SODIUM; SODIUM CHANNEL; SODIUM CHLORIDE; THIAZIDE DIURETIC AGENT;

EID: 33644835010     PISSN: 02709295     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.semnephrol.2005.09.008     Document Type: Article
Times cited : (31)

References (60)
  • 1
    • 0001182641 scopus 로고
    • A familial renal disorder simulating primary aldosteronism but with negligible aldosterone secretion
    • G.W.B.T. Liddle, W.S. Coppage A familial renal disorder simulating primary aldosteronism but with negligible aldosterone secretion Trans Am Assoc Phys 76 1963 199 213
    • (1963) Trans Am Assoc Phys , vol.76 , pp. 199-213
    • Liddle, G.W.B.T.1    Coppage, W.S.2
  • 2
    • 0001601125 scopus 로고
    • A salt wasting syndrome in infancy
    • D.B. Cheek, J.W. Perry A salt wasting syndrome in infancy Arch Dis Child 33 1958 252 256
    • (1958) Arch Dis Child , vol.33 , pp. 252-256
    • Cheek, D.B.1    Perry, J.W.2
  • 3
    • 0035936780 scopus 로고    scopus 로고
    • Molecular mechanisms of human hypertension
    • R.P. Lifton, A.G. Gharavi, D.S. Geller Molecular mechanisms of human hypertension Cell 104 2001 545 556
    • (2001) Cell , vol.104 , pp. 545-556
    • Lifton, R.P.1    Gharavi, A.G.2    Geller, D.S.3
  • 4
    • 0038690424 scopus 로고    scopus 로고
    • Trends in prevalence, awareness, treatment, and control of hypertension in the United States, 1988-2000
    • I. Hajjar, T.A. Kotchen Trends in prevalence, awareness, treatment, and control of hypertension in the United States, 1988-2000 JAMA 290 2003 199 206
    • (2003) JAMA , vol.290 , pp. 199-206
    • Hajjar, I.1    Kotchen, T.A.2
  • 5
    • 3442901072 scopus 로고    scopus 로고
    • The fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents
    • National High Blood Pressure Education Program Working Group on High Blood Pressure in Children and Adolescents
    • National High Blood Pressure Education Program Working Group on High Blood Pressure in Children and Adolescents The fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents Pediatrics 114 2004 555 576
    • (2004) Pediatrics , vol.114 , pp. 555-576
  • 6
    • 0034956918 scopus 로고    scopus 로고
    • The renal thiazide-sensitive Na-Cl cotransporter as mediator of the aldosterone-escape phenomenon
    • X.Y. Wang, S. Masilamani, J. Nielsen The renal thiazide-sensitive Na-Cl cotransporter as mediator of the aldosterone-escape phenomenon J Clin Invest 108 2001 215 222
    • (2001) J Clin Invest , vol.108 , pp. 215-222
    • Wang, X.Y.1    Masilamani, S.2    Nielsen, J.3
  • 7
    • 4644308674 scopus 로고    scopus 로고
    • Sodium and potassium handling by the aldosterone-sensitive distal nephron: The pivotal role of the distal and connecting tubule
    • P. Meneton, J. Loffing, D.G. Warnock Sodium and potassium handling by the aldosterone-sensitive distal nephron The pivotal role of the distal and connecting tubule Am J Physiol 287 2004 F593 F601
    • (2004) Am J Physiol , vol.287
    • Meneton, P.1    Loffing, J.2    Warnock, D.G.3
  • 8
    • 0033836651 scopus 로고    scopus 로고
    • Dynamic interactions between integrative physiology and molecular medicine: The key to understand the mechanism of action of aldosterone in the kidney
    • M.L. Halperin, K.S. Kamel Dynamic interactions between integrative physiology and molecular medicine The key to understand the mechanism of action of aldosterone in the kidney Can J Physiol Pharmacol 78 2000 587 594
    • (2000) Can J Physiol Pharmacol , vol.78 , pp. 587-594
    • Halperin, M.L.1    Kamel, K.S.2
  • 9
    • 0023743171 scopus 로고
    • Mineralocorticoid action: Target tissue specificity is enzyme, not receptor, mediated
    • J.W. Funder, P.T. Pearce, R. Smith Mineralocorticoid action Target tissue specificity is enzyme, not receptor, mediated Science 242 1988 583 585
    • (1988) Science , vol.242 , pp. 583-585
    • Funder, J.W.1    Pearce, P.T.2    Smith, R.3
  • 11
    • 0033517302 scopus 로고    scopus 로고
    • The effect of spironolactone on morbidity and mortality in patients with severe heart failure
    • Randomized Aldactone Evaluation Study Investigators W.J.
    • B. Pitt, F. Zannad, W.J. Remme Randomized Aldactone Evaluation Study Investigators The effect of spironolactone on morbidity and mortality in patients with severe heart failure N Engl J Med 341 1999 709 717
    • (1999) N Engl J Med , vol.341 , pp. 709-717
    • Pitt, B.1    Zannad, F.2    Remme3
  • 12
    • 24344433108 scopus 로고    scopus 로고
    • The mineralocorticoid receptor: A journey exploring its diversity and specificity of action
    • L. Pascual-Le Tallec, M. Lombes The mineralocorticoid receptor A journey exploring its diversity and specificity of action Mol Endocrinol 19 2005 2211 2221
    • (2005) Mol Endocrinol , vol.19 , pp. 2211-2221
    • Pascual-Le Tallec, L.1    Lombes, M.2
  • 13
  • 14
    • 0029160972 scopus 로고
    • Human hypertension caused by mutations in the kidney isozyme of 11 beta-hydroxysteroid dehydrogenase
    • T. Mune, F.M. Rogerson, H. Nikkila Human hypertension caused by mutations in the kidney isozyme of 11 beta-hydroxysteroid dehydrogenase Nat Genet 10 1995 394 399
    • (1995) Nat Genet , vol.10 , pp. 394-399
    • Mune, T.1    Rogerson, F.M.2    Nikkila, H.3
  • 15
    • 2342488106 scopus 로고    scopus 로고
    • Inactivating mutations of the mineralocorticoid receptor in type I pseudohypoaldosteronism
    • P. Sartorato, Y. Khaldi, A.L. Lapeyraque Inactivating mutations of the mineralocorticoid receptor in type I pseudohypoaldosteronism Mol Cell Endocrinol 217 2004 119 125
    • (2004) Mol Cell Endocrinol , vol.217 , pp. 119-125
    • Sartorato, P.1    Khaldi, Y.2    Lapeyraque, A.L.3
  • 16
    • 0031861245 scopus 로고    scopus 로고
    • Mutations in the mineralocorticoid receptor gene cause autosomal dominant pseudohypoaldosteronism type I
    • D.S. Geller, J. Rodriguez-Soriano, A. Vallo Boado Mutations in the mineralocorticoid receptor gene cause autosomal dominant pseudohypoaldosteronism type I Nat Genet 19 1998 279 281
    • (1998) Nat Genet , vol.19 , pp. 279-281
    • Geller, D.S.1    Rodriguez-Soriano, J.2    Vallo Boado, A.3
  • 17
    • 0027958441 scopus 로고
    • Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits
    • C.M. Canessa, L. Schild, G. Buell Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits Nature 367 1994 463 467
    • (1994) Nature , vol.367 , pp. 463-467
    • Canessa, C.M.1    Schild, L.2    Buell, G.3
  • 18
    • 0033578878 scopus 로고    scopus 로고
    • Number of subunits comprising the epithelial sodium channel
    • S. Eskandari, P.M. Snyder, M. Kreman Number of subunits comprising the epithelial sodium channel J Biol Chem 274 1999 27281 27286
    • (1999) J Biol Chem , vol.274 , pp. 27281-27286
    • Eskandari, S.1    Snyder, P.M.2    Kreman, M.3
  • 19
    • 0036307827 scopus 로고    scopus 로고
    • Epithelial sodium channel/degenerin family of ion channels: A variety of functions for a shared structure
    • S. Kellenberger, L. Schild Epithelial sodium channel/degenerin family of ion channels A variety of functions for a shared structure Physiol Rev 82 2002 735 767
    • (2002) Physiol Rev , vol.82 , pp. 735-767
    • Kellenberger, S.1    Schild, L.2
  • 20
    • 0030820814 scopus 로고    scopus 로고
    • The activity of the epithelial sodium channel is regulated by clathrin-mediated endocytosis
    • R.A. Shimkets, R.P. Lifton, C.M. Canessa The activity of the epithelial sodium channel is regulated by clathrin-mediated endocytosis J Biol Chem 272 1997 25537 25541
    • (1997) J Biol Chem , vol.272 , pp. 25537-25541
    • Shimkets, R.A.1    Lifton, R.P.2    Canessa, C.M.3
  • 21
    • 0035161876 scopus 로고    scopus 로고
    • A novel mouse Nedd4 protein suppresses the activity of the epithelial Na+ channel
    • E. Kamynina, C. Debonneville, M. Bens A novel mouse Nedd4 protein suppresses the activity of the epithelial Na+ channel FASEB J 15 2001 204 214
    • (2001) FASEB J , vol.15 , pp. 204-214
    • Kamynina, E.1    Debonneville, C.2    Bens, M.3
  • 22
    • 18244392958 scopus 로고    scopus 로고
    • Phosphorylation of Nedd4-2 by Sgk1 regulates epithelial Na(+) channel cell surface expression
    • C. Debonneville, S.Y. Flores, E. Kamynina Phosphorylation of Nedd4-2 by Sgk1 regulates epithelial Na(+) channel cell surface expression EMBO J 20 2001 7052 7059
    • (2001) EMBO J , vol.20 , pp. 7052-7059
    • Debonneville, C.1    Flores, S.Y.2    Kamynina, E.3
  • 23
    • 0027946089 scopus 로고
    • Liddle's syndrome: Heritable human hypertension caused by mutations in the beta subunit of the epithelial sodium channel
    • R.A. Shimkets, D.G. Warnock, C.M. Bositis Liddle's syndrome Heritable human hypertension caused by mutations in the beta subunit of the epithelial sodium channel Cell 79 1994 407 414
    • (1994) Cell , vol.79 , pp. 407-414
    • Shimkets, R.A.1    Warnock, D.G.2    Bositis, C.M.3
  • 24
    • 5144231108 scopus 로고    scopus 로고
    • Mechanisms of regulation of epithelial sodium channel by SGK1 in A6 cells
    • D. Alvarez de la Rosa, T.G. Paunescu, W.J. Els Mechanisms of regulation of epithelial sodium channel by SGK1 in A6 cells J Gen Physiol 124 2004 395 407
    • (2004) J Gen Physiol , vol.124 , pp. 395-407
    • Alvarez De La Rosa, D.1    Paunescu, T.G.2    Els, W.J.3
  • 25
    • 13344295074 scopus 로고    scopus 로고
    • Mutations in subunits of the epithelial sodium channel cause salt wasting with hyperkalaemic acidosis, pseudohypoaldosteronism type 1
    • S.S. Chang, S. Grunder, A. Hanukoglu Mutations in subunits of the epithelial sodium channel cause salt wasting with hyperkalaemic acidosis, pseudohypoaldosteronism type 1 Nat Genet 12 1996 248 253
    • (1996) Nat Genet , vol.12 , pp. 248-253
    • Chang, S.S.1    Grunder, S.2    Hanukoglu, A.3
  • 26
    • 0344373794 scopus 로고    scopus 로고
    • Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)
    • C.D. Furberg, J.T. Wright, B.R. David Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) JAMA 288 2002 2981 2997
    • (2002) JAMA , vol.288 , pp. 2981-2997
    • Furberg, C.D.1    Wright, J.T.2    David, B.R.3
  • 27
    • 0032564369 scopus 로고    scopus 로고
    • The thiazide-sensitive Na-Cl cotransporter is an aldosterone-induced protein
    • G.H. Kim, S. Masilamani, R. Turner The thiazide-sensitive Na-Cl cotransporter is an aldosterone-induced protein Proc Natl Acad Sci U S A 95 1998 14552 14557
    • (1998) Proc Natl Acad Sci U S a , vol.95 , pp. 14552-14557
    • Kim, G.H.1    Masilamani, S.2    Turner, R.3
  • 28
    • 0030019739 scopus 로고    scopus 로고
    • Adrenal steroids stimulate thiazide-sensitive NaCl transport by rat renal distal tubules
    • H. Velazquez, A. Bartiss, P. Bernstein Adrenal steroids stimulate thiazide-sensitive NaCl transport by rat renal distal tubules Am J Physiol 270 1996 F211 F219
    • (1996) Am J Physiol , vol.270
    • Velazquez, H.1    Bartiss, A.2    Bernstein, P.3
  • 29
    • 0036783548 scopus 로고    scopus 로고
    • Time course of renal Na-K-ATPase, NHE3, NKCC2, NCC, and ENaC abundance changes with dietary NaCl restriction
    • S. Masilamani, X. Wang, G.H. Kim Time course of renal Na-K-ATPase, NHE3, NKCC2, NCC, and ENaC abundance changes with dietary NaCl restriction Am J Physiol 283 2002 F648 F657
    • (2002) Am J Physiol , vol.283
    • Masilamani, S.1    Wang, X.2    Kim, G.H.3
  • 30
    • 0034911942 scopus 로고    scopus 로고
    • Loop diuretic infusion increases thiazide-sensitive Na(+)/Cl(-)- cotransporter abundance: Role of aldosterone
    • J.G. Abdallah, R.W. Schrier, C. Edelstein Loop diuretic infusion increases thiazide-sensitive Na(+)/Cl(-)-cotransporter abundance Role of aldosterone J Am Soc Nephrol 12 2001 1335 1341
    • (2001) J Am Soc Nephrol , vol.12 , pp. 1335-1341
    • Abdallah, J.G.1    Schrier, R.W.2    Edelstein, C.3
  • 31
    • 0013976561 scopus 로고
    • A new familial disorder characterized by hypokalemia and hypomagnesemia
    • H.J. Gitelman, J.B. Graham, L.G. Welt A new familial disorder characterized by hypokalemia and hypomagnesemia Trans Assoc Am Physicians 79 1966 221 235
    • (1966) Trans Assoc Am Physicians , vol.79 , pp. 221-235
    • Gitelman, H.J.1    Graham, J.B.2    Welt, L.G.3
  • 32
    • 0029794875 scopus 로고    scopus 로고
    • Genetic heterogeneity of Bartter's syndrome revealed by mutations in the K+ channel, ROMK
    • D.B. Simon, F.E. Karet, J. Rodriguez-Soriano Genetic heterogeneity of Bartter's syndrome revealed by mutations in the K+ channel, ROMK Nat Genet 14 1996 152 156
    • (1996) Nat Genet , vol.14 , pp. 152-156
    • Simon, D.B.1    Karet, F.E.2    Rodriguez-Soriano, J.3
  • 33
    • 0032698959 scopus 로고    scopus 로고
    • Defective processing and expression of thiazide-sensitive Na-Cl cotransporter as a cause of Gitelman's syndrome
    • S. Kunchaparty, M. Palcso, J. Berkman Defective processing and expression of thiazide-sensitive Na-Cl cotransporter as a cause of Gitelman's syndrome Am J Physiol 277 1999 F643 F649
    • (1999) Am J Physiol , vol.277
    • Kunchaparty, S.1    Palcso, M.2    Berkman, J.3
  • 34
    • 0036014925 scopus 로고    scopus 로고
    • Functional expression of mutations in the human NaCl cotransporter: Evidence for impaired routing mechanisms in Gitelman's syndrome
    • J.C. De Jong, W.A. Van Der Vliet, L.P. Van Den Heuvel Functional expression of mutations in the human NaCl cotransporter Evidence for impaired routing mechanisms in Gitelman's syndrome J Am Soc Nephrol 13 2002 1442 1448
    • (2002) J Am Soc Nephrol , vol.13 , pp. 1442-1448
    • De Jong, J.C.1    Van Der Vliet, W.A.2    Van Den Heuvel, L.P.3
  • 36
    • 2442680179 scopus 로고    scopus 로고
    • SGK1 increases Na,K-ATP cell-surface expression and function in Xenopus laevis oocytes
    • M. Zecevic, D. Heitzmann, S.M. Camargo SGK1 increases Na,K-ATP cell-surface expression and function in Xenopus laevis oocytes Pflugers Arch 448 2004 29 35
    • (2004) Pflugers Arch , vol.448 , pp. 29-35
    • Zecevic, M.1    Heitzmann, D.2    Camargo, S.M.3
  • 37
    • 0028924230 scopus 로고
    • Aldosterone modulates sodium kinetics of Na,K-ATPase containing an alpha 1 subunit in A6 kidney cell epithelia
    • J. Beron, L. Mastroberardino, A. Spillmann Aldosterone modulates sodium kinetics of Na,K-ATPase containing an alpha 1 subunit in A6 kidney cell epithelia Mol Biol Cell 6 1995 261 271
    • (1995) Mol Biol Cell , vol.6 , pp. 261-271
    • Beron, J.1    Mastroberardino, L.2    Spillmann, A.3
  • 38
    • 0033544885 scopus 로고    scopus 로고
    • Regulation of Na(+) reabsorption by the aldosterone-induced small G protein K-Ras2A
    • J.D. Stockand, B.J. Spier, R.T. Worrell Regulation of Na(+) reabsorption by the aldosterone-induced small G protein K-Ras2A J Biol Chem 274 1999 35449 35454
    • (1999) J Biol Chem , vol.274 , pp. 35449-35454
    • Stockand, J.D.1    Spier, B.J.2    Worrell, R.T.3
  • 39
    • 4444264303 scopus 로고    scopus 로고
    • Ras activates the epithelial Na(+) channel through phosphoinositide 3-OH kinase signaling
    • A. Staruschenko, P. Patel, Q. Tong Ras activates the epithelial Na(+) channel through phosphoinositide 3-OH kinase signaling J Biol Chem 279 2004 37771 37778
    • (2004) J Biol Chem , vol.279 , pp. 37771-37778
    • Staruschenko, A.1    Patel, P.2    Tong, Q.3
  • 40
    • 0033546341 scopus 로고    scopus 로고
    • Sgk is an aldosterone-induced kinase in the renal collecting duct. Effects on epithelial na+ channels
    • A. Naray-Fejes-Toth, C. Canessa, E.S. Cleaveland sgk is an aldosterone-induced kinase in the renal collecting duct. Effects on epithelial na+ channels J Biol Chem 274 1999 16973 16978
    • (1999) J Biol Chem , vol.274 , pp. 16973-16978
    • Naray-Fejes-Toth, A.1    Canessa, C.2    Cleaveland, E.S.3
  • 41
    • 0033514954 scopus 로고    scopus 로고
    • Epithelial sodium channel regulated by aldosterone-induced protein sgk
    • S.Y. Chen, A. Bhargava, L. Mastroberardino Epithelial sodium channel regulated by aldosterone-induced protein sgk Proc Natl Acad Sci U S A 96 1999 2514 2519
    • (1999) Proc Natl Acad Sci U S a , vol.96 , pp. 2514-2519
    • Chen, S.Y.1    Bhargava, A.2    Mastroberardino, L.3
  • 42
    • 0031663040 scopus 로고    scopus 로고
    • Cloning of sgk serine-threonine protein kinase from shark rectal gland - A gene induced by hypertonicity and secretagogues
    • S. Waldegger, P. Barth, J.N. Forrest Jr Cloning of sgk serine-threonine protein kinase from shark rectal gland - a gene induced by hypertonicity and secretagogues Pflugers Arch 436 1998 575 580
    • (1998) Pflugers Arch , vol.436 , pp. 575-580
    • Waldegger, S.1    Barth, P.2    Forrest Jr., J.N.3
  • 43
    • 0036088548 scopus 로고    scopus 로고
    • Hypotonic induction of SGK1 and Na+ transport in A6 cells
    • D.J. Rozansky, J. Wang, N. Doan Hypotonic induction of SGK1 and Na+ transport in A6 cells Am J Physiol 283 2002 F105 F113
    • (2002) Am J Physiol , vol.283
    • Rozansky, D.J.1    Wang, J.2    Doan, N.3
  • 44
    • 0035021426 scopus 로고    scopus 로고
    • SGK integrates insulin and mineralocorticoid regulation of epithelial sodium transport
    • J. Wang, P. Barbry, A.C. Maiyar SGK integrates insulin and mineralocorticoid regulation of epithelial sodium transport Am J Physiol 280 2001 F303 F313
    • (2001) Am J Physiol , vol.280
    • Wang, J.1    Barbry, P.2    Maiyar, A.C.3
  • 45
    • 0033151832 scopus 로고    scopus 로고
    • Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinase-stimulated signaling pathway
    • J. Park, M.L. Leong, P. Buse Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinase-stimulated signaling pathway EMBO J 18 1999 3024 3033
    • (1999) EMBO J , vol.18 , pp. 3024-3033
    • Park, J.1    Leong, M.L.2    Buse, P.3
  • 46
    • 14244254080 scopus 로고    scopus 로고
    • Nedd4-2 phosphorylation induces serum and glucocorticoid-regulated kinase (SGK) ubiquitination and degradation
    • R. Zhou, P.M. Snyder Nedd4-2 phosphorylation induces serum and glucocorticoid-regulated kinase (SGK) ubiquitination and degradation J Biol Chem 280 2005 4518 4523
    • (2005) J Biol Chem , vol.280 , pp. 4518-4523
    • Zhou, R.1    Snyder, P.M.2
  • 47
    • 0037564288 scopus 로고    scopus 로고
    • Short-term aldosterone action on Na,K-ATPase surface expression: Role of aldosterone-induced SGK1?
    • F. Verrey, V. Summa, D. Heitzmann Short-term aldosterone action on Na,K-ATPase surface expression Role of aldosterone-induced SGK1? Ann N Y Acad Sci 986 2003 554 561
    • (2003) Ann N Y Acad Sci , vol.986 , pp. 554-561
    • Verrey, F.1    Summa, V.2    Heitzmann, D.3
  • 48
    • 0035861678 scopus 로고    scopus 로고
    • Short term effect of aldosterone on Na,K-ATPase cell surface expression in kidney collecting duct cells
    • V. Summa, D. Mordasini, F. Roger Short term effect of aldosterone on Na,K-ATPase cell surface expression in kidney collecting duct cells J Biol Chem 276 2001 47087 47093
    • (2001) J Biol Chem , vol.276 , pp. 47087-47093
    • Summa, V.1    Mordasini, D.2    Roger, F.3
  • 49
    • 1642306540 scopus 로고    scopus 로고
    • Isoform specificity of human Na(+), K(+)-ATPase localization and aldosterone regulation in mouse kidney cells
    • V. Summa, S.M. Camargo, C. Bauch Isoform specificity of human Na(+), K(+)-ATPase localization and aldosterone regulation in mouse kidney cells J Physiol 555 2004 355 364
    • (2004) J Physiol , vol.555 , pp. 355-364
    • Summa, V.1    Camargo, S.M.2    Bauch, C.3
  • 50
    • 0036840696 scopus 로고    scopus 로고
    • Impaired renal Na(+) retention in the sgk1-knockout mouse
    • P. Wulff, V. Vallon, D.Y. Huang Impaired renal Na(+) retention in the sgk1-knockout mouse J Clin Invest 110 2002 1263 1268
    • (2002) J Clin Invest , vol.110 , pp. 1263-1268
    • Wulff, P.1    Vallon, V.2    Huang, D.Y.3
  • 51
    • 17944373014 scopus 로고    scopus 로고
    • Human hypertension caused by mutations in WNK kinases
    • F.H. Wilson, S. Disse-Nicodeme, K.A. Choate Human hypertension caused by mutations in WNK kinases Science 293 2001 1107 1112
    • (2001) Science , vol.293 , pp. 1107-1112
    • Wilson, F.H.1    Disse-Nicodeme, S.2    Choate, K.A.3
  • 52
    • 0037382807 scopus 로고    scopus 로고
    • WNK kinases regulate thiazide-sensitive Na-Cl cotransport
    • C.L. Yang, J. Angell, R. Mitchell WNK kinases regulate thiazide-sensitive Na-Cl cotransport J Clin Invest 111 2003 1039 1045
    • (2003) J Clin Invest , vol.111 , pp. 1039-1045
    • Yang, C.L.1    Angell, J.2    Mitchell, R.3
  • 53
    • 0345659215 scopus 로고    scopus 로고
    • WNK4 regulates the balance between renal NaCl reabsorption and K+ secretion
    • K.T. Kahle, F.H. Wilson, Q. Leng WNK4 regulates the balance between renal NaCl reabsorption and K+ secretion Nat Genet 35 2003 372 376
    • (2003) Nat Genet , vol.35 , pp. 372-376
    • Kahle, K.T.1    Wilson, F.H.2    Leng, Q.3
  • 54
    • 6944227814 scopus 로고    scopus 로고
    • Paracellular Cl- permeability is regulated by WNK4 kinase: Insight into normal physiology and hypertension
    • K.T. Kahle, G.G. Macgregor, F.H. Wilson Paracellular Cl- permeability is regulated by WNK4 kinase Insight into normal physiology and hypertension Proc Natl Acad Sci U S A 101 2004 14877 14882
    • (2004) Proc Natl Acad Sci U S a , vol.101 , pp. 14877-14882
    • Kahle, K.T.1    MacGregor, G.G.2    Wilson, F.H.3
  • 55
    • 18244373189 scopus 로고    scopus 로고
    • Mechanisms of WNK1 and WNK4 interaction in the regulation of thiazide-sensitive NaCl cotransport
    • C.L. Yang, X. Zhu, Z. Wang Mechanisms of WNK1 and WNK4 interaction in the regulation of thiazide-sensitive NaCl cotransport J Clin Invest 115 2005 1379 1387
    • (2005) J Clin Invest , vol.115 , pp. 1379-1387
    • Yang, C.L.1    Zhu, X.2    Wang, Z.3
  • 56
    • 0141455346 scopus 로고    scopus 로고
    • WNK1, a gene within a novel blood pressure control pathway, tissue-specifically generates radically different isoforms with and without a kinase domain
    • M. O'Reilly, E. Marshall, H.J. Speirs WNK1, a gene within a novel blood pressure control pathway, tissue-specifically generates radically different isoforms with and without a kinase domain J Am Soc Nephrol 14 2003 2447 2456
    • (2003) J Am Soc Nephrol , vol.14 , pp. 2447-2456
    • O'Reilly, M.1    Marshall, E.2    Speirs, H.J.3
  • 57
    • 10644223454 scopus 로고    scopus 로고
    • The kidney-specific WNK1 isoform is induced by aldosterone and stimulates epithelial sodium channel-mediated Na+ transport
    • A. Naray-Fejes-Toth, P.M. Snyder, G. Fejes-Toth The kidney-specific WNK1 isoform is induced by aldosterone and stimulates epithelial sodium channel-mediated Na+ transport Proc Natl Acad Sci U S A 101 2004 17434 17439
    • (2004) Proc Natl Acad Sci U S a , vol.101 , pp. 17434-17439
    • Naray-Fejes-Toth, A.1    Snyder, P.M.2    Fejes-Toth, G.3
  • 58
    • 4744369165 scopus 로고    scopus 로고
    • Identification of 108 SNPs in TSC, WNK1, and WNK4 and their association with hypertension in a Japanese general population
    • Y. Kokubo, K. Kamide, N. Inamoto Identification of 108 SNPs in TSC, WNK1, and WNK4 and their association with hypertension in a Japanese general population J Hum Genet 49 2004 507 515
    • (2004) J Hum Genet , vol.49 , pp. 507-515
    • Kokubo, Y.1    Kamide, K.2    Inamoto, N.3
  • 59
    • 15944412561 scopus 로고    scopus 로고
    • Regulation of diverse ion transport pathways by WNK4 kinase: A novel molecular switch
    • K.T. Kahle, F.H. Wilson, R.P. Lifton Regulation of diverse ion transport pathways by WNK4 kinase A novel molecular switch Trends Endocrinol Metab 16 2005 98 103
    • (2005) Trends Endocrinol Metab , vol.16 , pp. 98-103
    • Kahle, K.T.1    Wilson, F.H.2    Lifton, R.P.3
  • 60
    • 0025817650 scopus 로고
    • Blood pressure control-special role of the kidneys and body fluids
    • A.C. Guyton Blood pressure control-special role of the kidneys and body fluids Science 252 1991 1813 1816
    • (1991) Science , vol.252 , pp. 1813-1816
    • Guyton, A.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.