Puerariae radix promotes differentiation and mineralization in human osteoblast-like SaOS-2 cells

Journal of Ethnopharmacology

Volumn 104, Issue 3, 2006, Pages 345-350

  Huh, Jeong Eun ^a   Yang, Ha Ru ^a   Park, Dong Suk ^a   Choi, Do Young ^a   Baek, Yong Hyeon ^a   Cho, Eun Mi ^a   Cho, Yoon Je ^b   Kang Il, Kim ^b   Kim, Deog Yoon ^b   Lee, Jae Dong ^a  

^a Kyung Hee University   (South Korea)

^b Kyung Hee University Hospital   (South Korea)

Author keywords

ALP activity; Col I; Mineralization; OCN; OPN; Puerariae radix; VEGF

Indexed keywords

ALKALINE PHOSPHATASE; COLLAGEN TYPE 1; MATRIX PROTEIN; MESSENGER RNA; OSTEOCALCIN; OSTEOPONTIN; PLANT EXTRACT; PUERARIAE RADIX EXTRACT; UNCLASSIFIED DRUG; VASCULOTROPIN;

ARTICLE; BONE DEVELOPMENT; BONE MINERALIZATION; CELL CULTURE; CELL DIFFERENTIATION; CELL VIABILITY; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MINERALIZATION; OSTEOBLAST; PLANT ROOT; PROTEIN EXPRESSION; PUERARIA;

ALKALINE PHOSPHATASE; CALCIFICATION, PHYSIOLOGIC; CELL DIFFERENTIATION; CELL LINE; COLLAGEN TYPE I; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUGS, CHINESE HERBAL; GENE EXPRESSION; HUMANS; OSTEOBLASTS; OSTEOCALCIN; OSTEOPONTIN; PUERARIA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIALOGLYCOPROTEINS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

PUERARIA;

EID: 33644822791     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2005.09.041     Document Type: Article

References (19)

1. T. Arao, M. Udayama, J. Kinjo, T. Nohara, T. Funakoshi, and S. Kojima Preventive effects of saponins from Puerariae radix (the root of Pueraria lobata Ohwi) on in vitro immunological injury of rat primary hepatocyte cultures Biological & Pharmaceutical Bulletin 20 1997 988 991
2. J.E. Aubin, F. Liu, L. Malaval, and A.K. Gupta Osteoblast and chondroblast differentiation Bone 17 1995 77S 83S
3. M.M. Deckers, M. Karperien, C. van der Bent, T. Yamashita, S.E. Papapoulos, and C.W. Lowik Expression of vascular endothelial growth factors and their receptors during osteoblast differentiation Endocrinology 141 2000 1667 1674
4. R.T. Franceschi, and B.S. Iyer Relationship between collagen synthesis and expression of the osteoblast phenotype in MC3T3-E1 cells Journal of Bone and Mineral Research 7 1992 235 246
5. T. Furumatsu, Z.N. Shen, A. Kawai, K. Nishida, H. Manabe, T. Oohashi, H. Inoue, and Y. Ninomiya Vascular endothelial growth factor principally acts as the main angiogenic factor in the early stage of human osteoblastogenesis Journal of Biochemistry 133 2003 633 639
6. H.P. Gerber, T.H. Vu, A.M. Ryan, J. Kowalski, Z. Werb, and N. Ferrara VEGF couples hypertropic cartilage remodeling, and angiogenesis during endochondral bone formation Nature Medicine 5 1999 623 628
7. D.L. Goad, J. Rubin, H. Wang, A.H. Tashjian Jr., and C. Patterson Enhanced expression of vascular endothelial growth factor in human SaOS-2 osteoblast-like cells and murine osteoblasts induced by insulin-like growth factor I Endocrinology 137 1996 2262 2268
8. M.C. Guerra, E. Speroni, M. Broccoli, M. Cangini, P. Pasini, A. Minghett, N. Crespi-Perellino, M. Mirasoli, G. Cantelli-Forti, and M. Paolini Comparison between Chinese medical herb Pueraria lobata crude extract and its main isoflavone puerarin antioxidant properties and effects on rat liver CYP-catalysed drug metabolism Life Sciences 7 2000 2997 3006
9. F.J. Hughes, J. Collyer, M. Stanfield, and S.A. Goodman The effects of bone morphogenic protein-2, -4, and -6 on differentiation of rat osteoblast cells in vitro Endocrinology 136 1995 2671 2677
10. G.K. Hunter, P.V. Hauschka, A.R. Poole, L.C. Rosenberg, and H.A. Goldberg Nucleation and inhibition of hydroxyapatite formation by mineralized tissue proteins The Biochemical Journal 317 1996 59 64
11. X.L. Lai, and B. Tang Recent advances in the experimental study and clinical application of Pueraria lobata (Willd) Ohwi Zhongguo Zhong Yao Za Zhi 14 1989 308 311
12. J.B. Lian, G.S. Stein, and A.L. Boskey Bone formation: maturation and functional activists osteoblast linease cells M.J. Favus Primer on the metabolic bone diseases and disorders of mineral metabolism. fifth ed. 2003 The American Society for Bone and Mineral Research Washington DC 13 28
13. T. Maeda, T. Kawane, and N. Horiuchi Statins augument vascular endothelial growth factor expression in osteoblastic cells via inhibition of protein prenylation Endocrinology 144 2003 681 692
14. T. Maeda, A. Matsunuma, T. Kawane, and N. Horiuchi Simvastatin promotes osteoblast differentiation and mineralization in MC3T3-E1 cells Biochemical and Biophysical Research Communications 280 2001 874 877
15. C. Maes, P. Carmeliet, K. Moermans, I. Stockmans, N. Smets, D. Collen, R. Bouillon, and G. Carmeliet Impaired angiogenesis and endochondral bone formation in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188 Mechanisms of Development 111 2003 61 73
16. T.L. McCarthy, M. Centrella, and E. Canalis Regulatory effects of insulin-like growth factors I and on bone collagen synthesis in rat calvarial cultures Endocrinology 124 1989 301 309
17. V. Midy, and J. Plouet Vasculotropin/vascular endothelial growth factor induces differentiation in cultured osteoblasts Biochemical and Biophysical Research Communications 199 1994 380 386
18. T.C. Spelsberg, M. Subramaniam, B.L. Riggs, and S. Khosla The actions and interactions of sex steroids and growth factors/cytokines on the skeleton Molecular Endocrinology 13 1999 819 828
19. X. Wang, J. Wu, H. Chiba, K. Umegaki, K. Yamada, and Y. Ishimi Puerariae radix prevents bone loss in ovariectomized mice Journal of Bone and Mineral Metabolism 21 2003 268 275