메뉴 건너뛰기




Volumn 34, Issue 1-2, 2006, Pages 177-183

Cardioprotective effect of hydroxyfasudil as a specific Rho-kinase inhibitor, on ischemia-reperfusion injury in canine coronary microvessels in vivo

Author keywords

Coronary microcirculation; Ischemia reperfusion; Nitric oxide; Rho kinase inhibitor

Indexed keywords

ACETYLCHOLINE; FASUDIL; HYDROXYFASUDIL; PAPAVERINE; RHO KINASE INHIBITOR; UNCLASSIFIED DRUG;

EID: 33644794902     PISSN: 13860291     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper
Times cited : (10)

References (30)
  • 1
    • 0023108266 scopus 로고
    • Reperfusion after acute coronary occlusion in dogs impairs endothelium-dependent relaxation to acetylcholine and augments contractile reactivity in vitro
    • P.J. Vanbenthuysen, I.F. McMurtry and L.D. Horwitz, Reperfusion after acute coronary occlusion in dogs impairs endothelium-dependent relaxation to acetylcholine and augments contractile reactivity in vitro, J. Clin. Invest. 79 (1987), 265-274.
    • (1987) J. Clin. Invest. , vol.79 , pp. 265-274
    • Vanbenthuysen, P.J.1    McMurtry, I.F.2    Horwitz, L.D.3
  • 2
    • 0024591883 scopus 로고
    • Impaired canine coronary vasodilator response to acetylcholine and bradykinin after occlusion-reperfusion
    • J.L. Mehta, W.W. Nichols, W.H. Donnelly and D.L. Lawson, Impaired canine coronary vasodilator response to acetylcholine and bradykinin after occlusion-reperfusion, Circ. Res. 64 (1989), 43-54.
    • (1989) Circ. Res. , vol.64 , pp. 43-54
    • Mehta, J.L.1    Nichols, W.W.2    Donnelly, W.H.3    Lawson, D.L.4
  • 3
    • 0025365812 scopus 로고
    • Acute impairment of endothelium-dependent relaxations to aggregating platelets following reperfusion injury in canine coronary arteries
    • P.J. Pearson, H.V. Schaff and P.M. Vanhoutte, Acute impairment of endothelium-dependent relaxations to aggregating platelets following reperfusion injury in canine coronary arteries, Circ. Res. 67 (1990), 385-393.
    • (1990) Circ. Res. , vol.67 , pp. 385-393
    • Pearson, P.J.1    Schaff, H.V.2    Vanhoutte, P.M.3
  • 4
    • 0027301196 scopus 로고
    • Preconditioning protects coronary arteriolar endothelium from ischemia-reperfusion injury
    • D.V. Defily and W.M. Chilian, Preconditioning protects coronary arteriolar endothelium from ischemia-reperfusion injury, Am. J. Physiol. 265 (1993), H700-H706.
    • (1993) Am. J. Physiol. , vol.265
    • Defily, D.V.1    Chilian, W.M.2
  • 5
    • 0024312198 scopus 로고
    • Endothelium-derived relaxing factor and coronary spasm
    • P.M. Vanhoutte and H. Shimokawa, Endothelium-derived relaxing factor and coronary spasm, Circulation 80 (1989), 1-9.
    • (1989) Circulation , vol.80 , pp. 1-9
    • Vanhoutte, P.M.1    Shimokawa, H.2
  • 6
    • 0022393927 scopus 로고
    • The role of oxygen-derived free radicals in ischemia-induced increases in canine skeletal muscle vascular permeability
    • R.J. Korthuis, D.N. Granger, M.I. Townsley and A.E. Taylor, The role of oxygen-derived free radicals in ischemia-induced increases in canine skeletal muscle vascular permeability, Circ. Res. 57 (1985), 599-609.
    • (1985) Circ. Res. , vol.57 , pp. 599-609
    • Korthuis, R.J.1    Granger, D.N.2    Townsley, M.I.3    Taylor, A.E.4
  • 7
    • 0023620353 scopus 로고
    • Reduction of reperfusion injury in the canine preparation by intracoronary adenosine: Importance of the endothelium and the no-reflow phenomenon
    • B. Olafsson, M.B. Forman, D.W. Puett, A. Pou, C.U. Cates, G.C. Friesinger and R. Virmani, Reduction of reperfusion injury in the canine preparation by intracoronary adenosine: importance of the endothelium and the no-reflow phenomenon, Circulation 76 (1987), 1135-1145.
    • (1987) Circulation , vol.76 , pp. 1135-1145
    • Olafsson, B.1    Forman, M.B.2    Puett, D.W.3    Pou, A.4    Cates, C.U.5    Friesinger, G.C.6    Virmani, R.7
  • 8
    • 0021022198 scopus 로고
    • 5-Hydroxytryptamine can mediate endothelium-dependent relaxation of coronary arteries
    • R.A. Cohen, J.T. Shepherd and P.M. Vanhoutte, 5-Hydroxytryptamine can mediate endothelium-dependent relaxation of coronary arteries, Am. J. Physiol. 245 (1983), H1077-H1080.
    • (1983) Am. J. Physiol. , vol.245
    • Cohen, R.A.1    Shepherd, J.T.2    Vanhoutte, P.M.3
  • 9
    • 0022005518 scopus 로고
    • Removal of endothelium potentiates canine large coronary artery constrictor response to 5-hydroxytryptamine in vivo
    • K.G. Lamping, M.L. Marcus and W.P. Dole, Removal of endothelium potentiates canine large coronary artery constrictor response to 5-hydroxytryptamine in vivo, Circ. Res. 57 (1985), 46-54.
    • (1985) Circ. Res. , vol.57 , pp. 46-54
    • Lamping, K.G.1    Marcus, M.L.2    Dole, W.P.3
  • 10
    • 0036182417 scopus 로고    scopus 로고
    • Rho-kinase as a novel therapeutic target in treatment of cardiovascular diseases
    • H. Shimokawa, Rho-kinase as a novel therapeutic target in treatment of cardiovascular diseases, J. Cardiovasc. Pharmacol. 39 (2002), 319-327.
    • (2002) J. Cardiovasc. Pharmacol. , vol.39 , pp. 319-327
    • Shimokawa, H.1
  • 13
    • 0036645303 scopus 로고    scopus 로고
    • Rho-kinase mediates hypoxia-induced downregulation of endothelial nitric oxide synthase
    • M. Takemoto, J. Sun, J. Hiroki, H. Shimokawa and J.K. Liao, Rho-kinase mediates hypoxia-induced downregulation of endothelial nitric oxide synthase, Circulation 106 (2002), 57-62.
    • (2002) Circulation , vol.106 , pp. 57-62
    • Takemoto, M.1    Sun, J.2    Hiroki, J.3    Shimokawa, H.4    Liao, J.K.5
  • 14
    • 0035838950 scopus 로고    scopus 로고
    • Pharmacological profile of hydroxy fasudil as a selective Rho-kinase inhibitor on ischemic brain damage
    • S. Satoh, T. Utsunomiya, K. Tsurui, T. Kobayashi, I. Ikegaki, Y. Sasaki and T. Asano, Pharmacological profile of hydroxy fasudil as a selective Rho-kinase inhibitor on ischemic brain damage, Life Sci. 69 (2001), 1441-1453.
    • (2001) Life Sci. , vol.69 , pp. 1441-1453
    • Satoh, S.1    Utsunomiya, T.2    Tsurui, K.3    Kobayashi, T.4    Ikegaki, I.5    Sasaki, Y.6    Asano, T.7
  • 15
    • 0027468239 scopus 로고
    • In vivo observation of subendocardial microvessels of the beating porcine heart using a needle-probe videomicroscope with a CCD camera
    • T. Yada, O. Hiramatsu, A. Kimura, M. Goto, Y. Ogasawara, K. Tsujioka, S. Yamamori, K. Ohno, H. Hosaka and F. Kajiya, In vivo observation of subendocardial microvessels of the beating porcine heart using a needle-probe videomicroscope with a CCD camera, Circ. Res. 72 (1993), 939-946.
    • (1993) Circ. Res. , vol.72 , pp. 939-946
    • Yada, T.1    Hiramatsu, O.2    Kimura, A.3    Goto, M.4    Ogasawara, Y.5    Tsujioka, K.6    Yamamori, S.7    Ohno, K.8    Hosaka, H.9    Kajiya, F.10
  • 21
    • 0036181829 scopus 로고    scopus 로고
    • Nitric oxide induces dilation of rat aorta via inhibition of Rho-kinase signaling
    • K. Chitaley and R.C. Webb, Nitric oxide induces dilation of rat aorta via inhibition of Rho-kinase signaling, Hypertension 39 (2002), 438-442.
    • (2002) Hypertension , vol.39 , pp. 438-442
    • Chitaley, K.1    Webb, R.C.2
  • 22
    • 0027378613 scopus 로고
    • Inhibition by the protein kinase inhibitor HA1077 of the activation of NADPH oxidase in human neutrophils
    • M. Arai, Y. Sasaki and R. Nozawa, Inhibition by the protein kinase inhibitor HA1077 of the activation of NADPH oxidase in human neutrophils, Biochem. Pharmacol. 46 (1993), 1487-1490.
    • (1993) Biochem. Pharmacol. , vol.46 , pp. 1487-1490
    • Arai, M.1    Sasaki, Y.2    Nozawa, R.3
  • 24
    • 0022970945 scopus 로고
    • Preconditioning with ischemia: A delay of lethal cell injury in ischemic myocardium
    • C.E. Murry, R.B. Jennings and K.A. Reimer, Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium, Circulation 74 (1986), 1124-1136.
    • (1986) Circulation , vol.74 , pp. 1124-1136
    • Murry, C.E.1    Jennings, R.B.2    Reimer, K.A.3
  • 25
    • 0025999672 scopus 로고
    • Preconditioning causes improved wall motion as well as smaller infarcts after transient coronary occlusion in rabbits
    • M.V. Cohen, G.S. Liu and J.M. Downey, Preconditioning causes improved wall motion as well as smaller infarcts after transient coronary occlusion in rabbits, Circulation 84 (1991), 341-349.
    • (1991) Circulation , vol.84 , pp. 341-349
    • Cohen, M.V.1    Liu, G.S.2    Downey, J.M.3
  • 27
    • 0035678906 scopus 로고    scopus 로고
    • Antianginal effects of hydroxyfasudil, a Rho-kinase inhibitor, in a canine model of effort angina
    • T. Utsunomiya, S. Satoh, I. Ikegaki, Y. Toshima, T. Asano and H. Shimokawa, Antianginal effects of hydroxyfasudil, a Rho-kinase inhibitor, in a canine model of effort angina, Br. J. Physiol. 134 (2001), 1724-1730.
    • (2001) Br. J. Physiol. , vol.134 , pp. 1724-1730
    • Utsunomiya, T.1    Satoh, S.2    Ikegaki, I.3    Toshima, Y.4    Asano, T.5    Shimokawa, H.6
  • 28
    • 0037007054 scopus 로고    scopus 로고
    • Suppression of coronary artery spasm by the Rho-kinase inhibitor fasudil in patients with vasospastic angina
    • A. Masumoto, M. Mohri, H. Shimokawa, L. Urakami, M. Usui and A. Takeshita, Suppression of coronary artery spasm by the Rho-kinase inhibitor fasudil in patients with vasospastic angina, Circulation 105 (2002), 1545-1547.
    • (2002) Circulation , vol.105 , pp. 1545-1547
    • Masumoto, A.1    Mohri, M.2    Shimokawa, H.3    Urakami, L.4    Usui, M.5    Takeshita, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.