Effects of intraperitoneal vitamin E, melatonin and aprotinin on leptin expression in the guinea pig eye during experimental uveitis

Acta Ophthalmologica Scandinavica

Volumn 84, Issue 1, 2006, Pages 54-61

  Kükner, Aysel ^a   Çolakoǧlu, Neriman ^b   Serin, Didem ^a   Alagöz, Gürsoy ^a   Çelebi, Serdal ^a   Kükner, A Şahap ^a  

^a ABANT IZZET BAYSAL UNIVERSITY   (Turkey)

^b FIRAT UNIVERSITY   (Turkey)

Author keywords

Aprotinin; Experimental uveitis; Leptin; Melatonin; Vitamin E

Indexed keywords

ALPHA TOCOPHEROL SUCCINATE; APROTININ; BOVINE SERUM ALBUMIN; LEPTIN; MELATONIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CHOROID; CONTROLLED STUDY; CORNEA; DISEASE SEVERITY; DRUG MECHANISM; GENE EXPRESSION; GUINEA PIG; HISTOPATHOLOGY; MALE; NONHUMAN; PRIORITY JOURNAL; RETINA; SCLERA; SCORING SYSTEM; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; UVEITIS;

ANIMALS; ANTIOXIDANTS; APROTININ; CHOROID; DISEASE MODELS, ANIMAL; FREE RADICAL SCAVENGERS; GUINEA PIGS; IMMUNOENZYME TECHNIQUES; INJECTIONS, INTRAPERITONEAL; LEPTIN; MALE; MELATONIN; RETINA; RETINAL GANGLION CELLS; SCLERA; SERINE PROTEINASE INHIBITORS; SERUM ALBUMIN, BOVINE; UVEITIS; VITAMIN E;

EID: 33644764090     PISSN: 13953907     EISSN: 16000420     Source Type: Journal    
DOI: 10.1111/j.1600-0420.2005.00544.x     Document Type: Article

References (45)

1. Balasubramaniam J, Kumar MT, Pandit JK & Kant S (2001): In vitro and in vivo characterization of scleral implants of indomethacin. Pharmazie 56: 793-799.
2. Bozkurt A, Cakir B, Ercan F & Yegen BC (2003): Anti-inflammatory effects of leptin and cholecystokinin on acetic acid-induced colitis in rats: Role of capsaicin-sensitive vagal afferent fibres. Regul Pept 15: 109-118.
3. Busso N, Chobaz-Peclat V, Morard C, Martinez-Soria E, Talabot-Ayer D & Gabay C (2002): Leptin signalling deficiency impairs humoral and cellular immune responses and attenuates experimental arthritis. J Immunol 168: 875-882.
4. Cakir B, Bozkurt A, Ercan F & Yegen BC (2004): The anti-inflammatory effect of leptin on experimental colitis: Involvement of endogenous glucocorticoids. Peptides 25: 95-104.
5. Cakir B, Cevik H, Contuk G, Ercan F, Eksioglu-Demiralp E & Yegen BC (2005): Leptin ameliorates burn-induced multiple organ damage and modulates postburn immune response in rats. Regul Pept 15: 135-144.
6. Cao R, Brakenhielm E, Wahlestedt C, Thyberg J & Cao Y (2001): Leptin induces vascular permeability and synergistically stimulates angiogenesis with FGF-2 and VEGF. Proc Natl Acad Sci U S A 22: 6390-6395.
7. Çelebi S, Dilsiz N, Yilmaz T & Kükner AS (2002): Effects of melatonin, vitamin E and octreotide on lipid peroxidation during ischaemia-reperfusion in the guinea pig retina. Eur J Ophthalmol 12: 77-83.
8. Dadoukis J, Angouridakis K & Aletras H (1981): Action of the basic trypsin inhibitor, Trasylol, on shock resulting from occlusion of the superior mesenteric artery. Experimental study. J Int Med Res 9: 31-38.
9. Evereklioglu. C, Inalöz HS, Kirtak N, Doganay S, Bülbül M, Özerol E. Er H,Özbek E (2002): Serum leptin concentration is increased in patients with Behçet's syndrome and is correlated with disease activity. Br J Dermatol 147: 331-336.
10. Gariano RF, Nath AK, D'Amico DJ, Lee T & Sierra-Honigmann MR (2000): Elevation of vitreous leptin in diabetic retinopathy and retinal detachment. Invest Ophthalmol Vis Sci 41: 3576-3581.
11. Gündüz B (2002): Daily rhythm in serum melatonin and leptin levels in the Syrian hamster (Mesoricetus auratus). Comp Biochem Physiol A Mol Integr Physiol 132: 393-401.
12. Halliwell B & Gutteridge JM (1996): Protection against radical damage: Systems with problems. In: Halliwell B & Gutteridge JM (eds). Free Radicals in Biology and Medicine. Oxford: Clarendon Press 289-298.
13. Hill GE, Alonso A, Spurzem RS, Stammers AH & Robbins RA (1995): Aprotinin and methylprednisolone equally blunt cardiopulmonary bypass-induced inflammation in humans. J Thorac Cardiovasc Surg 110: 1658-1662.
14. Hu S, Li S, Xie C, Pan S, Huang X & Mao W (1992): Effects of qingkailing on experimental allergic uveitis in rabbits. Yan Ke Xue Bao 8: 138-142.
15. Isermann B, Bierhaus A, Tritschler H, Ziegler R & Nawroth PP (1999): Alpha-tocopherol induces leptin expression in healthy individuals and in vitro. Diabetes Care 22: 1227-1228.
16. Ishimoto SL, Wu GS, Hayashi S, Zhang J & Rao NA (1996): Free radical tissue damages in the anterior segment of the eye in experimental autoimmune uveitis. Invest Ophthalmol Vis Sci 37: 630-636.
17. Kökçam I & Naziroglu M (2002): Effects of vitamin E supplementation on blood antioxidant levels in patients with Behçet's disease. Clin Biochem 35: 633-639.
18. Kükner AS, Kükner A, Naziroglu M, Çolakoglu N, Çelebi S, Yilmaz T & Aydemir O (2004): Protective effects of intraperitoneal vitamin C, aprotinin and melatonin administration on retinal oedema during experimental uveitis in the guinea pig. Cell Biochem Funct 22: 299-305.
19. Loeser RF (2003): Systemic and local regulation of articular cartilage metabolism: Where does leptin fit in the puzzle? Arthritis Rheum 48: 3009-3012.
20. Matarese G, Sanna V, Di Giacomo A et al. (2001): Leptin potentiates experimental autoimmune encephalomyelitis in SJL female mice and confers susceptibility to males. Eur J Immunol 31: 1324-1332.
21. Matarese G, Sanna V, Lechler RI, Sarvetnick N, Fontana S, Zappacosta S & La Cava A (2002): Leptin accelerates autoimmune diabetes in female NOD mice. Diabetes 51: 1356-1361.
22. Mathew JP, Thomas VC & Thomas I (2003): Selenite cataract and its attenuation by vitamin E in Wistar rats. Indian J Ophthalmol 51: 161-170.
23. Otero M, Gomez-Reino JJ & Gualillo O (2003): Leptin synergizes interleukin-1 in inducing nitric oxide synthase in chondrocytes. Arthritis Rheum 48: 654.
24. Özer Z, Sucu N, Düsmez D, Tamer L, Altunkan AA & Dikmengil M (2001): The effect of aprotinin on ischaemia-reperfusion injury in the rabbit kidney. Pharmacol Res 44: 460. 455-460
25. Perlman JI, Shuber H, Selvaraj RP & Cassidy EM (1999): Free radical generation following pressure-induced retinal ischaemia in the rat. Retina 19: 255-257.
26. Pierrefiche G, Topal G, Courboin G, Henriet I & Laborit H (1993): Antioxidant activity of melatonin in mice. Res Commun Chem Pathol Pharmacol 80: 211-223.
27. Prunet-Marcassus B, Desbazeille M, Bros A, Louche K, Delagrange P, Renard P, Casteilla L & Pánicaud L (2003): Melatonin reduces body weight gain in Sprague Dawley rats with diet-induced obesity. Endocrinology 144: 5347-5352.
28. Rahman A, Üstündag B, Burma O, Özercan HI, Çekirdekçi A & Bayar MK (2000): Does aprotinin reduce lung reperfusion damage after cardiopulmonary bypass? Eur J Cardiothorac Surg 18: 583-588.
29. Rao NA & Guey-Shuang W (2000): Free radical mediated photoreceptor damage in uveitis. Prog Retinal Eye Res 19: 41-68.
30. Rasmussen DD, Boldt BM, Wilkinson CW, Yellon SM & Matsumoto AM (1999): Daily melatonin administration at middle age suppresses male rat visceral fat, plasma leptin, and plasma insulin to youthful levels. Endocrinology 140: 1009-1012.
31. Reiter RJ, Tan DX, Manchester LC & Calvo JR (2000): Antioxidant capacity of melatonin. In: Cadenas E & Packer L (eds). Handbook of Antioxidants. 2nd edn. New York: Marcel Dekker 565-614.
32. Reiter RJ, Tan D, Sainz RM, Mayo JC & Burillo SL (2002): Melatonin: reducing the toxicity and increasing the efficacy of drugs. J Pharm Pharmacol 54: 1299-1321.
33. Saoudi A, Hurez V, De Kozak Y, Kuhn J, Kaveri SV, Kazatchkine MD, Druet P & Bellon B (1993): Human immunoglobulin preparations for intravenous use prevent experimental autoimmune uveoretinitis. Int Immunol 5: 1559-1567.
34. Sfikakis PP, Theodossiadis PG, Katsiari CG, Kaklamanis P & Markomichelakis NN (2001): Effect of infliximab on sight-threatening panuveitis in Behçet's disease. Lancet 358: 295-296.
35. Siegmund B, Sennello JA, Jones-Carson J et al. (2004): Leptin receptor expression on T lymphocytes modulates chronic intestinal inflammation in mice. Gut 53: 965-972.
36. Vrabec TR, Gregerson DS, Dua HS & Donoso LA (1992): Inhibition of experimental autoimmune uveoretinitis by oral administration of S-antigen and synthetic peptides. Autoimmunity 12: 175-184.
37. Warzecha Z, Dembinski A, Ceranowicz P, Jaworek J, Konturek PC, Dembinski M, Bilskl J & Konturek SJ (2002): Influence of leptin administration on the course of acute ischaemic pancreatitis. J Physiol Pharmacol 53: 775-790.
38. Westaby S (1993): Aprotinin in perspective. Ann Thorac Surg 55: 1033-1041.
39. Wiegand RD, Joel CD, Rapp LM, Nielsen JC, Maude MB & Anderson RE (1986): Polyunsaturated fatty acids and vitamin E in rat rod outer segments during light damage. Invest Ophthalmol Vis Sci 27: 727-733.
40. Wu GS & Walker J, Rao NA (1993): Effect of deferoxamine on retinal lipid peroxidation in experimental uveitis. Invest Ophthalmol Vis Sci 34: 3084-3089.
41. Yamauchi H, Iso T & Iwata H (1979): Ocular anti-inflammatory and systemic immunosuppressive effects of topically applied fluorometholone. Jpn J Pharmacol 29: 87-92.
42. Yargiçoglu P, Yaras N, Agar A, Gümüslü S, Bilmen S & Özkaya G (2003): The effect of vitamin E on stress-induced changes in visual evoked potentials (VEPs) in rats exposed to different experimental stress models. Acta Ophthalmol Scand 81: 181-187.
43. Yue KK, Chung WS, Leung AW & Cheng CH (2003): Redox changes precede the occurrence of oxidative stress in eyes and aorta, but not in kidneys of diabetic rats. Life Sci 73: 2557-2570.
44. Yilmaz T, Çelebi S & Kükner A (2002): The protective effects of melatonin, vitamin E and octreotide on retinal oedema during ischaemia-reperfusion in the guinea pig retina. Eur J Ophthalmol 12: 443-449.
45. Yilmaz T, Kükner AS, Aydemir O, Özercan HI, & Naziroglu M (2003): Aprotinin reduces ischaemia-reperfusion injury in the retina of guinea pigs. Eur J Opthalmol 13:642-647.