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M. Senoo, N. Mochida, L. Wang, Y. Matsumura, D. Suzuki, N. Takeda, Y. Shinkai, and S. Habu Limited effect of chromatin remodeling on D(beta)-to-J(beta) recombination in CD4+CD8+ thymocyte: implications for a new aspect in the regulation of TCR beta gene recombination Int Immunol 13 2001 1405 1414
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Int Immunol
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Senoo, M.1
Mochida, N.2
Wang, L.3
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Suzuki, D.5
Takeda, N.6
Shinkai, Y.7
Habu, S.8
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52
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0038381431
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Assessing the role of the T cell receptor beta gene enhancer in regulating coding joint formation during V(D)J recombination
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N. Mathieu, S. Spicuglia, S. Gorbatch, O. Cabaud, C. Fernex, C. Verthuy, W.M. Hempel, A.O. Hueber, and P. Ferrier Assessing the role of the T cell receptor beta gene enhancer in regulating coding joint formation during V(D)J recombination J Biol Chem 278 2003 18101 18109
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Mathieu, N.1
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Cabaud, O.4
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Verthuy, C.6
Hempel, W.M.7
Hueber, A.O.8
Ferrier, P.9
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53
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0344392275
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The T cell receptor beta enhancer promotes access and pairing of Dbeta and Jbeta gene segments during V(D)J recombination
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C.J. Ryu, B.B. Haines, D.D. Draganov, Y.H. Kang, C.E. Whitehurst, T. Schmidt, H.J. Hong, and J. Chen The T cell receptor beta enhancer promotes access and pairing of Dbeta and Jbeta gene segments during V(D)J recombination Proc Natl Acad Sci USA 100 2003 13465 13470
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Ryu, C.J.1
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Whitehurst, C.E.5
Schmidt, T.6
Hong, H.J.7
Chen, J.8
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54
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3543011330
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The T-cell receptor beta variable gene promoter is required for efficient V beta rearrangement but not allelic exclusion
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C.J. Ryu, B.B. Haines, H.R. Lee, Y.H. Kang, D.D. Draganov, M. Lee, C.E. Whitehurst, H.J. Hong, and J. Chen The T-cell receptor beta variable gene promoter is required for efficient V beta rearrangement but not allelic exclusion Mol Cell Biol 24 2004 7015 7023
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Ryu, C.J.1
Haines, B.B.2
Lee, H.R.3
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Lee, M.6
Whitehurst, C.E.7
Hong, H.J.8
Chen, J.9
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55
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Regulation of T cell receptor beta allelic exclusion at a level beyond accessibility
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A. Jackson, H.D. Kondilis, B. Khor, B.P. Sleckman, and M.S. Krangel Regulation of T cell receptor beta allelic exclusion at a level beyond accessibility Nat Immunol 6 2005 189 197 In this knock-in study, the TCRα gene enhancer was introduced downstream of the Vβ12 gene segment. Despite increased Vβ accessibility and germline transcription in double-positive thymocytes, the inhibition of Vβ-to-DJβ rearrangement appears to be maintained. Following flow cytometry analysis to identify double TCRβ-expressing cells, the authors conclude that allelic exclusion at Vβ12 was partially subverted in double-negative thymocytes.
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Nat Immunol
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Jackson, A.1
Kondilis, H.D.2
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Allele-specific regulation of TCRβ variable gene segment chromatin structure
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A.M. Jackson, and M.S. Krangel Allele-specific regulation of TCRβ variable gene segment chromatin structure J Immunol 175 2005 5186 5191
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Jackson, A.M.1
Krangel, M.S.2
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15444362020
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Mechanisms controlling termination of V-J recombination at the TCRγ locus: Implications for allelic and isotypic exclusion of TCRγ chains
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L. Boucontet, N. Sepulveda, J. Carneiro, and P. Pereira Mechanisms controlling termination of V-J recombination at the TCRγ locus: implications for allelic and isotypic exclusion of TCRγ chains J Immunol 174 2005 3912 3919
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Boucontet, L.1
Sepulveda, N.2
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Pereira, P.4
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59
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E47 is required for V(D)J recombinase activity in common lymphoid progenitors
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L. Borghesi, J. Aites, S. Nelson, P. Lefterov, P. James, and R. Gerstein E47 is required for V(D)J recombinase activity in common lymphoid progenitors J Exp Med 202 2005 1669 1677
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Borghesi, L.1
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Nelson, S.3
Lefterov, P.4
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Gerstein, R.6
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