메뉴 건너뛰기




Volumn 100, Issue 11, 2005, Pages 2438-2446

Hypoadiponectinemia predicts the severity of hepatic fibrosis and pancreatic beta-cell dysfunction in nondiabetic nonobese patients with nonalcoholic steatohepatitis

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOCYTOKINE; ADIPONECTIN; GLUCOSE; TUMOR NECROSIS FACTOR ALPHA;

EID: 33644636469     PISSN: 00029270     EISSN: 15720241     Source Type: Journal    
DOI: 10.1111/j.1572-0241.2005.00297.x     Document Type: Article
Times cited : (182)

References (45)
  • 1
    • 0038805259 scopus 로고    scopus 로고
    • The prevalence and etiology of elevated aminotransferase levels in the United States
    • Clark JM Brancati FL Diehl AME. The prevalence and etiology of elevated aminotransferase levels in the United States. Am J Gastroenterol 2003 98 : 960 67.
    • (2003) Am J Gastroenterol , vol.98 , pp. 960-67
    • Clark, J.M.1    Brancati, F.L.2    Diehl, A.M.E.3
  • 2
    • 0000279908 scopus 로고    scopus 로고
    • MBFL. Nonalcoholic fatty liver disease and the risk of type 2 diabetes in the United States
    • abstract).
    • Clark JM Diehl A. MBFL. Nonalcoholic fatty liver disease and the risk of type 2 diabetes in the United States. Diabetes 2001 50 : A38 ( abstract).
    • (2001) Diabetes , vol.50
    • Clark, J.M.1    Diehl, A.2
  • 3
    • 0036263238 scopus 로고    scopus 로고
    • High alanine aminotransferase is associated with decreased hepatic insulin sensitivity and predicts the development of type 2 diabetes
    • Vozarova B Stefan N Lindsay RS, et al. High alanine aminotransferase is associated with decreased hepatic insulin sensitivity and predicts the development of type 2 diabetes. Diabetes 2002 51 : 1889 95.
    • (2002) Diabetes , vol.51 , pp. 1889-95
    • Vozarova, B.1    Stefan, N.2    Lindsay, R.S.3
  • 4
    • 7044274423 scopus 로고    scopus 로고
    • Elevated alanine aminotransferase predicts new-onset type 2 diabetes independently of classical risk factors, metabolic syndrome, and C-reactive protein in the West of Scotland Coronary Prevention Study
    • Sattar N Scherbakova O Ford I, et al. Elevated alanine aminotransferase predicts new-onset type 2 diabetes independently of classical risk factors, metabolic syndrome, and C-reactive protein in the West of Scotland Coronary Prevention Study. Diabetes 2004 53 : 2855 60.
    • (2004) Diabetes , vol.53 , pp. 2855-60
    • Sattar, N.1    Scherbakova, O.2    Ford, I.3
  • 5
    • 0032695030 scopus 로고    scopus 로고
    • Independent predictors of liver fibrosis in patients with nonalcoholic steatohepatitis
    • Angulo P Keach JC Batts KP, et al. Independent predictors of liver fibrosis in patients with nonalcoholic steatohepatitis. Hepatology 1999 30 : 1356 62.
    • (1999) Hepatology , vol.30 , pp. 1356-62
    • Angulo, P.1    Keach, J.C.2    Batts, K.P.3
  • 6
    • 0842321807 scopus 로고    scopus 로고
    • Diabetes increases the risk of chronic liver disease and hepatocellular carcinoma
    • El-Serag HB Tran T Everhart JE. Diabetes increases the risk of chronic liver disease and hepatocellular carcinoma. Gastroenterology 2004 126 : 460 8.
    • (2004) Gastroenterology , vol.126 , pp. 460-8
    • El-Serag, H.B.1    Tran, T.2    Everhart, J.E.3
  • 8
    • 18244385511 scopus 로고    scopus 로고
    • Nonalcoholic steatohepatitis, insulin resistance and metabolic syndrome: Further evidence for an etiologic association
    • Pagano G Pacini G Musso G, et al. Nonalcoholic steatohepatitis, insulin resistance and metabolic syndrome: Further evidence for an etiologic association. Hepatology 2002 35 : 367 72.
    • (2002) Hepatology , vol.35 , pp. 367-72
    • Pagano, G.1    Pacini, G.2    Musso, G.3
  • 9
    • 0034853485 scopus 로고    scopus 로고
    • The importance of β-cell failure in the development and progression of type 2 diabetes
    • Kahn SE. The importance of β-cell failure in the development and progression of type 2 diabetes. J Clin Endocrinol Metab 2001 86 : 4047 58.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 4047-58
    • Kahn, S.E.1
  • 10
    • 0035132672 scopus 로고    scopus 로고
    • Insulin resistance and insulin secretory dysfunction are independent predictors of worsening of glucose tolerance during each stage of type 2 diabetes development
    • Weyer C Tataranni PA Bogardus C, et al. Insulin resistance and insulin secretory dysfunction are independent predictors of worsening of glucose tolerance during each stage of type 2 diabetes development. Diabetes Care 2000 24 : 89 94.
    • (2000) Diabetes Care , vol.24 , pp. 89-94
    • Weyer, C.1    Tataranni, P.A.2    Bogardus, C.3
  • 11
    • 0036616582 scopus 로고    scopus 로고
    • Identifying the links between obesity, insulin resistance and β-cell function: Potential role of adipocyte-derived cytokines in the pathogenesis of type 2 diabetes
    • Greenberg AS McDaniel ML. Identifying the links between obesity, insulin resistance and β-cell function: Potential role of adipocyte-derived cytokines in the pathogenesis of type 2 diabetes. Eur J Clin Invest 2002 32 ( suppl 3 24 34.
    • (2002) Eur J Clin Invest , vol.32 , Issue.3 , pp. 24-34
    • Greenberg, A.S.1    McDaniel, M.L.2
  • 12
    • 12144291012 scopus 로고    scopus 로고
    • Adiponectin gene polymorphisms and adiponectin levels are independently associated with the development of hyperglycemia during a 3-year period. the epidemiologic data on the insulin resistance syndrome prospective study
    • Fumeron F Aubert A Siddiq A, et al. Adiponectin gene polymorphisms and adiponectin levels are independently associated with the development of hyperglycemia during a 3-year period. The epidemiologic data on the insulin resistance syndrome prospective study. Diabetes 2004 53 : 1150 7.
    • (2004) Diabetes , vol.53 , pp. 1150-7
    • Fumeron, F.1    Aubert, A.2    Siddiq, A.3
  • 13
    • 3042744737 scopus 로고    scopus 로고
    • Beyond insulin resistance in NASH: TNF-α or adiponectin?
    • Hui JM Hodge A Farrell GC, et al. Beyond insulin resistance in NASH: TNF-α or adiponectin? Hepatology 2004 40 : 46 54.
    • (2004) Hepatology , vol.40 , pp. 46-54
    • Hui, J.M.1    Hodge, A.2    Farrell, G.C.3
  • 14
    • 0035083842 scopus 로고    scopus 로고
    • Nonalcoholic steatohepatitis: Definition and pathology
    • Brunt EM. Nonalcoholic steatohepatitis: Definition and pathology. Semin Liver Dis 2001 21 : 3 16.
    • (2001) Semin Liver Dis , vol.21 , pp. 3-16
    • Brunt, E.M.1
  • 15
    • 0030894257 scopus 로고    scopus 로고
    • Relative validity and reproducibility of a food frequency dietary questionnaire for use in the Italian EPIC centres
    • Pisani P Faggiano F Krogh V, et al. Relative validity and reproducibility of a food frequency dietary questionnaire for use in the Italian EPIC centres. Int J Epidemiol 1997 26 ( suppl 1 S152 60.
    • (1997) Int J Epidemiol , vol.26 , Issue.1
    • Pisani, P.1    Faggiano, F.2    Krogh, V.3
  • 19
    • 0029793137 scopus 로고    scopus 로고
    • Toward an integrated phenotype in pre-NIDDM
    • Bergman RN Watanabe R Rebrin K, et al. Toward an integrated phenotype in pre-NIDDM. Diabet Med 1996 13 : S67 77.
    • (1996) Diabet Med , vol.13
    • Bergman, R.N.1    Watanabe, R.2    Rebrin, K.3
  • 21
    • 0027375768 scopus 로고
    • Quantification of the relationship between insulin sensitivity and beta-cell function in human subjects. Evidence for a hyperbolic function
    • Kahn SE Prigeon RL McCulloch DK, et al. Quantification of the relationship between insulin sensitivity and beta-cell function in human subjects. Evidence for a hyperbolic function. Diabetes 1993 42 : 1663 72.
    • (1993) Diabetes , vol.42 , pp. 1663-72
    • Kahn, S.E.1    Prigeon, R.L.2    McCulloch, D.K.3
  • 22
    • 0030716888 scopus 로고    scopus 로고
    • Impaired adaptation of first phase insulin secretion in postmenopausal women with glucose intolerance
    • Ahrén B Pacini G. Impaired adaptation of first phase insulin secretion in postmenopausal women with glucose intolerance. Am J Physiol 1997 273 : E701 7.
    • (1997) Am J Physiol , vol.273
    • Ahrén, B.1    Pacini, G.2
  • 23
    • 1542270658 scopus 로고    scopus 로고
    • Importance of quantifying insulin secretion in relation to insulin sensitivity to accurately assess beta cell function in clinical studies
    • Ahrén B Pacini G. Importance of quantifying insulin secretion in relation to insulin sensitivity to accurately assess beta cell function in clinical studies. Eur J Endocrinol 2004 150 : 97 104.
    • (2004) Eur J Endocrinol , vol.150 , pp. 97-104
    • Ahrén, B.1    Pacini, G.2
  • 24
    • 0035897696 scopus 로고    scopus 로고
    • Executive summary of the third report of the national cholesterol education program (NCEP) export panel on detection, evaluation and treatment of high blood cholesterol in adults (Adult treatment panel III)
    • Executive summary of the third report of the national cholesterol education program (NCEP) export panel on detection, evaluation and treatment of high blood cholesterol in adults (Adult treatment panel III). JAMA 2001 285 : 2486 97.
    • (2001) JAMA , vol.285 , pp. 2486-97
  • 25
    • 0037382071 scopus 로고    scopus 로고
    • Dietary habits and their relations to insulin resistance and postprandial lipemia in nonalcoholic steatohepatitis
    • Musso G Gambino R De Michieli F, et al. Dietary habits and their relations to insulin resistance and postprandial lipemia in nonalcoholic steatohepatitis. Hepatology 2003 37 : 909 16.
    • (2003) Hepatology , vol.37 , pp. 909-16
    • Musso, G.1    Gambino, R.2    De Michieli, F.3
  • 26
    • 0842289935 scopus 로고    scopus 로고
    • Clinical Practice Recommendations 2004
    • Clinical Practice Recommendations 2004. Diabetes Care 2004 27 : S5 10.
    • (2004) Diabetes Care , vol.27
  • 28
    • 6944227798 scopus 로고    scopus 로고
    • Metabolic significance of nonalcoholic fatty liver disease in nonobese, nondiabetic adults
    • Kim HJ Kim HJ Lee KE, et al. Metabolic significance of nonalcoholic fatty liver disease in nonobese, nondiabetic adults. Arch Intern Med 2004 164 : 2169 75.
    • (2004) Arch Intern Med , vol.164 , pp. 2169-75
    • Kim, H.J.1    Kim, H.J.2    Lee, K.E.3
  • 29
    • 17544374575 scopus 로고    scopus 로고
    • Contribution of reduced insulin sensitivity and secretion to the pathogenesis of hepatogenous diabetes: Effect of liver transplantation
    • Perseghin G Mazzaferro V Sereni LP, et al. Contribution of reduced insulin sensitivity and secretion to the pathogenesis of hepatogenous diabetes: Effect of liver transplantation. Hepatology 2000 31 : 694 703.
    • (2000) Hepatology , vol.31 , pp. 694-703
    • Perseghin, G.1    Mazzaferro, V.2    Sereni, L.P.3
  • 30
    • 0034207939 scopus 로고    scopus 로고
    • Nutrient toxicity in pancreatic beta-cell dysfunction
    • Roche E Maestre I Martin F, et al. Nutrient toxicity in pancreatic beta-cell dysfunction. J Physiol Biochem 2000 56 : 119 28.
    • (2000) J Physiol Biochem , vol.56 , pp. 119-28
    • Roche, E.1    Maestre, I.2    Martin, F.3
  • 31
    • 0035156817 scopus 로고    scopus 로고
    • Distinct effects of saturated and monounsaturated fatty acids on cell turnover and function
    • Maedler K Spinas GA Dyntar D, et al. Distinct effects of saturated and monounsaturated fatty acids on cell turnover and function. Diabetes 2001 50 : 69 76.
    • (2001) Diabetes , vol.50 , pp. 69-76
    • Maedler, K.1    Spinas, G.A.2    Dyntar, D.3
  • 32
    • 17644407937 scopus 로고    scopus 로고
    • Signals adapting the beta cells to changes in insulin sensitivity
    • In: Crepaldi, G. Tiengo, A. Avogaro, A., eds. Excerpta Medica ICS 1253. New York: Elsevier
    • Ahrén B Pacini G. Signals adapting the beta cells to changes in insulin sensitivity. In : Crepaldi G Tiengo A Avogaro A, eds. The Metabolic Syndrome: Diabetes, Obesity, Hyperlipidemia & Hypertension, Excerpta Medica ICS 1253. New York : Elsevier, 2003 : 105 13.
    • (2003) The Metabolic Syndrome: Diabetes, Obesity, Hyperlipidemia & Hypertension , pp. 105-13
    • Ahrén, B.1    Pacini, G.2
  • 33
    • 1542284737 scopus 로고    scopus 로고
    • Adiponectin counteracts cytokine- and fatty acid-induced apoptosis in the pancreatic beta-cell line INS-1
    • Rakatxi I Mueller H Ritzeler O, et al. Adiponectin counteracts cytokine- and fatty acid-induced apoptosis in the pancreatic beta-cell line INS-1. Diabetologia 2004 47 : 249 58.
    • (2004) Diabetologia , vol.47 , pp. 249-58
    • Rakatxi, I.1    Mueller, H.2    Ritzeler, O.3
  • 34
    • 7044260753 scopus 로고    scopus 로고
    • Pioglitazone reduces islet triglyceride content and restores impaired glucose-stimulated insulin secretion in heterozygous peroxisome proliferator-activated receptor-χ-deficient mice on a high-fat diet
    • Matsui J Terauchi Y Kubota N, et al. Pioglitazone reduces islet triglyceride content and restores impaired glucose-stimulated insulin secretion in heterozygous peroxisome proliferator-activated receptor-χ-deficient mice on a high-fat diet. Diabetes 2004 53 : 2844 54.
    • (2004) Diabetes , vol.53 , pp. 2844-54
    • Matsui, J.1    Terauchi, Y.2    Kubota, N.3
  • 35
    • 0028839110 scopus 로고
    • Interaction between free fatty acids and insulin in the acute control of very low density lipoprotein production in humans
    • Lewis GF Uffelman KD Szeto LW, et al. Interaction between free fatty acids and insulin in the acute control of very low density lipoprotein production in humans. J Clin Invest 1995 95 : 158 66.
    • (1995) J Clin Invest , vol.95 , pp. 158-66
    • Lewis, G.F.1    Uffelman, K.D.2    Szeto, L.W.3
  • 36
    • 0027299436 scopus 로고
    • Effects of acute hyperinsulinemia on VLDL triglyceride and VLDL ApoB production in normal weight and obese individuals
    • Lewis GF Uffelman KD Szeto LW, et al. Effects of acute hyperinsulinemia on VLDL triglyceride and VLDL ApoB production in normal weight and obese individuals. Diabetes 1993 42 : 833 42.
    • (1993) Diabetes , vol.42 , pp. 833-42
    • Lewis, G.F.1    Uffelman, K.D.2    Szeto, L.W.3
  • 37
    • 0030986959 scopus 로고    scopus 로고
    • Detective regulation of triglyceride metabolism by insulin in the liver in NIDDM
    • Malmstrom R Packard CJ Caslake M, et al. Detective regulation of triglyceride metabolism by insulin in the liver in NIDDM. Diabetologia 1997 40 : 454 62.
    • (1997) Diabetologia , vol.40 , pp. 454-62
    • Malmstrom, R.1    Packard, C.J.2    Caslake, M.3
  • 38
    • 0036312905 scopus 로고    scopus 로고
    • Fat accumulation in the liver is associated with defects in insulin suppression of glucose production and serum free fatty acids independent of obesity in normal men
    • Seppala-Lindroos A Vehkavaara S Hakkinen AM, et al. Fat accumulation in the liver is associated with defects in insulin suppression of glucose production and serum free fatty acids independent of obesity in normal men. J Clin Endocrinol Metab 2002 87 : 3023 8.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 3023-8
    • Seppala-Lindroos, A.1    Vehkavaara, S.2    Hakkinen, A.M.3
  • 39
    • 0842313004 scopus 로고    scopus 로고
    • Decreased plasma adiponectin concentrations are closely related to hepatic fat content and hepatic insulin resistance in pioglitazone-treated type 2 diabetic patients
    • Bajaj M Suraamornkul S Piper P, et al. Decreased plasma adiponectin concentrations are closely related to hepatic fat content and hepatic insulin resistance in pioglitazone-treated type 2 diabetic patients. J Clin Endocrinol Metab 2004 89 : 200 6.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 200-6
    • Bajaj, M.1    Suraamornkul, S.2    Piper, P.3
  • 40
    • 0041302377 scopus 로고    scopus 로고
    • The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice
    • Xu A Wang Y Keshaw H. The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice. J Clin Invest 2003 112 : 91 100.
    • (2003) J Clin Invest , vol.112 , pp. 91-100
    • Xu, A.1    Wang, Y.2    Keshaw, H.3
  • 41
    • 3042699353 scopus 로고    scopus 로고
    • Adiponectin protects LPS-induced liver injury through modulation of TNF-α in KK-Ay obese mice
    • Masaki T Chiba S Tatsukawa H, et al. Adiponectin protects LPS-induced liver injury through modulation of TNF-α in KK-Ay obese mice. Hepatology 2004 40 : 177 84.
    • (2004) Hepatology , vol.40 , pp. 177-84
    • Masaki, T.1    Chiba, S.2    Tatsukawa, H.3
  • 42
    • 10744228583 scopus 로고    scopus 로고
    • Enhanced carbon tetrachloride-induced liver fibrosis in mice lacking adiponectin
    • Kamada Y Tamura S Kiso S, et al. Enhanced carbon tetrachloride-induced liver fibrosis in mice lacking adiponectin. Gastroenterology 2003 125 : 1796 807.
    • (2003) Gastroenterology , vol.125 , pp. 1796-807
    • Kamada, Y.1    Tamura, S.2    Kiso, S.3
  • 43
    • 4644297019 scopus 로고    scopus 로고
    • Natural history of nonalcoholic steatohepatitis: A longitudinal study of repeat liver biopsies
    • Fassio E Alvarez E Dominguez N, et al. Natural history of nonalcoholic steatohepatitis: A longitudinal study of repeat liver biopsies. Hepatology 2004 40 : 820 6.
    • (2004) Hepatology , vol.40 , pp. 820-6
    • Fassio, E.1    Alvarez, E.2    Dominguez, N.3
  • 44
    • 1442352339 scopus 로고    scopus 로고
    • Role of the adypocyte, free fatty acids, and ectopic fat in the pathogenesis of type 2 diabetes mellitus: Peroxisomal proliferator-activated receptor agonists provide a rational therapeutic approach
    • Bays H Mandarino L DeFronzo R. Role of the adypocyte, free fatty acids, and ectopic fat in the pathogenesis of type 2 diabetes mellitus: Peroxisomal proliferator-activated receptor agonists provide a rational therapeutic approach. J Clin Endocrinol Metab 2004 89 : 463 78.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 463-78
    • Bays, H.1    Mandarino, L.2    Defronzo, R.3
  • 45
    • 3242745192 scopus 로고    scopus 로고
    • Effects of rosiglitazone and metformin on liver fat content, hepatic insulin resistance, insulin clearance, and gene expression in adipose tissue in patients with type 2 diabetes
    • Tiikkainen M Hakkinen AM Korsheninnikova E, et al. Effects of rosiglitazone and metformin on liver fat content, hepatic insulin resistance, insulin clearance, and gene expression in adipose tissue in patients with type 2 diabetes. Diabetes 2004 53 : 2169 76.
    • (2004) Diabetes , vol.53 , pp. 2169-76
    • Tiikkainen, M.1    Hakkinen, A.M.2    Korsheninnikova, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.