Discriminative stimulus properties of the atypical antipsychotic drug clozapine in rats trained to discriminate 1.25 mg/kg clozapine vs. 5.0 mg/kg clozapine vs. vehicle

Behavioural Pharmacology

Volumn 17, Issue 2, 2006, Pages 185-194

  Prus, Adam J ^a   Philibin, Scott D ^b   Pehrson, Alan L ^b   Porter, Joseph H ^b  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

Antipsychotic drugs; Clozapine; Drug discrimination; Rat; Receptor; Stimulus properties; Training dose

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; ATYPICAL ANTIPSYCHOTIC AGENT; CLOZAPINE; DOPAMINE 1 RECEPTOR BLOCKING AGENT; DOPAMINE 4 RECEPTOR BLOCKING AGENT; DOPAMINE RECEPTOR BLOCKING AGENT; DRUG VEHICLE; LU 38 012; MECAMYLAMINE; MEPYRAMINE; MIANSERIN; MUSCARINIC M1 RECEPTOR AGONIST; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; NICOTINIC RECEPTOR BLOCKING AGENT; NORCLOZAPINE; PRAZOSIN; RITANSERIN; RO 4368554; SCOPOLAMINE; SEROTONIN 1A AGONIST; SEROTONIN 1A ANTAGONIST; SEROTONIN 2A ANTAGONIST; SEROTONIN 2B ANTAGONIST; SEROTONIN 2C ANTAGONIST; SEROTONIN 6 ANTAGONIST; SEROTONIN ANTAGONIST; UNCLASSIFIED DRUG; UNINDEXED DRUG; YOHIMBINE;

ANIMAL EXPERIMENT; ARTICLE; CONDITIONED REFLEX; CONDITIONING; DISCRIMINATIVE STIMULUS; DRUG ANTAGONISM; DRUG DISCRIMINATION; DRUG MECHANISM; DRUG SUBSTITUTION; MALE; NONHUMAN; RAT; STIMULUS GENERALIZATION; TRAINING;

ANIMALS; ANTIPSYCHOTIC AGENTS; CLOZAPINE; CUES; DATA INTERPRETATION, STATISTICAL; DISCRIMINATION (PSYCHOLOGY); DISCRIMINATION LEARNING; DOSE-RESPONSE RELATIONSHIP, DRUG; GENERALIZATION, STIMULUS; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, BIOGENIC AMINE;

EID: 33644608161     PISSN: 09558810     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.fbp.0000197457.70774.91     Document Type: Article

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