Granulocyte macrophage-colony stimulating factor reduces the affinity of SHP-2 for the ITIM of CLECSF6 in neutrophils: A new mechanism of action for SHP-2

Molecular Immunology

Volumn 43, Issue 10, 2006, Pages 1716-1721

  Richard, Manon ^a   Thibault, Nathalie ^a   Veilleux, Patricia ^a   Gareau Pagé, Geneviève ^a   Beaulieu, André D ^a  

^a LAVAL UNIVERSITY   (Canada)

Author keywords

CLECSF6; DCIR; Detergent; GM CSF; Inflammation; ITIM; Neutrophil; Peptide; Phosphatase; SHIP 1; SHP 1; SHP 2; Signal transduction; Tyrosine phosphorylation

Indexed keywords

GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; LECTIN; PROTEIN C TYPE LECTIN SUPERFAMILY 6; PROTEIN IMMUNORECEPTOR TYROSINE BASED INHIBITOR MOTIF; PROTEIN TYROSINE PHOSPHATASE SHP 1; PROTEIN TYROSINE PHOSPHATASE SHP 2; TYROSINE; UNCLASSIFIED DRUG;

ARTICLE; CELL ACTIVATION; ENZYME ACTIVITY; ENZYME MECHANISM; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PHOSPHORYLATION;

AMINO ACID MOTIFS; DETERGENTS; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LECTINS, C-TYPE; MEMBRANE GLYCOPROTEINS; NEUTROPHILS; PEPTIDES; PHOSPHORIC MONOESTER HYDROLASES; PHOSPHORYLATION; PROTEIN-TYROSINE-PHOSPHATASE; RECEPTORS, IMMUNOLOGIC; SHP1 PROTEIN TYROSINE PHOSPHATASE; TYROSINE;

EID: 33644598183     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2005.10.006     Document Type: Article

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