Peptidoglycan recognition proteins Pglyrp3 and Pglyrp4 are encoded from the epidermal differentiation complex and are candidate genes for the Psors4 locus on chromosome 1q21

Human Genetics

Volumn 119, Issue 1-2, 2006, Pages 113-125

  Sun, Chao ^a   Mathur, Punam ^a   Dupuis, Josée ^b   Tizard, Rich ^a   Ticho, Barry ^a   Crowell, Tom ^a   Gardner, Humphrey ^a   Bowcock, Anne M ^c   Carulli, John ^a  

^a BIOGEN   (United States)

^b BOSTON UNIVERSITY   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PATTERN RECOGNITION RECEPTOR; PEPTIDOGLYCAN RECOGNITION PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CASE CONTROL STUDY; CELLULAR DISTRIBUTION; CHROMOSOME 1Q; CLUSTER ANALYSIS; CONTROLLED STUDY; DISEASE SEVERITY; EPIDERMIS; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENETIC LINKAGE; GERMINAL CENTER; HAPLOTYPE; HUMAN; HUMAN CELL; HUMAN TISSUE; INNATE IMMUNITY; MAJOR CLINICAL STUDY; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PSORIASIS; SINGLE NUCLEOTIDE POLYMORPHISM; TONSIL;

CARRIER PROTEINS; CASE-CONTROL STUDIES; CELLS, CULTURED; CHROMOSOMES, HUMAN, PAIR 1; FAMILY HEALTH; FEMALE; GENE EXPRESSION PROFILING; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; IMMUNOHISTOCHEMISTRY; LINKAGE DISEQUILIBRIUM; MALE; PALATINE TONSIL; POLYMORPHISM, SINGLE NUCLEOTIDE; PSORIASIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SKIN; TONSIL;

BACTERIA (MICROORGANISMS);

EID: 33644553496     PISSN: 03406717     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00439-005-0115-8     Document Type: Article

References (58)

1. Baker BS, Ovigne JM, Fischetti VA, Powles A, Fry L (2003a) Reduced IFN-gamma responses associated with HLA-DR15 presentation of streptococcal cell wall proteins to dermal Th-1 cells in psoriasis. J Clin Immunol 23:407-414
2. Baker BS, Ovigne JM, Powles AV, Corcoran S, Fry L (2003b) Normal keratinocytes express Toll-like receptors (TLRs) 1, 2 and 5: Modulation of TLR expression in chronic plaque psoriasis. Br J Dermatol 148:670-679
3. Becker KG, Simon RM, Bailey-Wilson JE, Freidlin B, Biddison WE, McFarland HF, Trent JM (1998) Clustering of non-major histocompatibility complex susceptibility candidate loci in human autoimmune diseases. Proc Natl Acad Sci USA 95:9979-9984
4. Benoist C, Mathis D (2001) Autoimmunity provoked by infection: How good is the case for T cell epitope mimicry? Nat Immunol 2:797-801
5. Beutler B (2004) Inferences, questions and possibilities in Toll-like receptor signalling. Nature 430:257-263
6. Beutler B, Beutler E (2002) Toll-like receptor 4 polymorphisms and atherogenesis. N Engl J Med 347:1978-1980 (author reply 1978-1980)
7. Bhalerao J, Bowcock AM (1998) The genetics of psoriasis: A complex disorder of the skin and immune system. Hum Mol Genet 7:1537-1545
8. Bikle DD, Ng D, Tu CL, Oda Y, Xie Z (2001) Calcium- and vitamin D-regulated keratinocyte differentiation. Mol Cell Endocrinol 177:161-171
9. Blumberg H, Conklin D, Xu WF, Grossmann A, Brender T, Carollo S, Eagan M, Foster D, Haldeman BA, Hammond A, Haugen H, Jelinek L, Kelly JD, Madden K, Maurer MF, Parrish-Novak J, Prunkard D, Sexson S, Sprecher C, Waggie K, West J, Whitmore TE, Yao L, Kuechle MK, Dale BA, Chandrasekher YA (2001) Interleukin 20: Discovery, receptor identification, and role in epidermal function. Cell 104:9-19
10. Bowcock AM, Cookson WO (2004) The genetics of psoriasis, psoriatic arthritis and atopic dermatitis. Hum Mol Genet 13 Spec No 1:R43-R55
11. + T cells produce interferon-gamma in vitro in response to streptococcal antigens in chronic plaque psoriasis. J Invest Dermatol 114:576-580
12. Capon F, Novelli G, Semprini S, Clementi M, Nudo M, Vultaggio P, Mazzanti C, Gobello T, Botta A, Fabrizi G, Dallapiccola B (1999) Searching for psoriasis susceptibility genes in Italy: Genome scan and evidence for a new locus on chromosome 1. J Invest Dermatol 112:32-34
13. Capon F, Semprini S, Chimenti S, Fabrizi G, Zambruno G, Murgia S, Carcassi C, Fazio M, Mingarelli R, Dallapiccola B, Novelli G (2001) Fine mapping of the PSORS4 psoriasis susceptibility region on chromosome 1q21. J Invest Dermatol 116:728-730
14. Clayton D (1999) A generaliztion of the transmission/disequilibrium test for uncertain-haplotype transmission. Am J Hum Gen 65:1170-1177
15. Cookson WOCM, Ubhi B, Lawrence R, Abecasis GR, Walley AJ, Cox HE, Coleman R, Leaves NI, Trembath RC, Moffatt MF, Harper JI (2001) Genetic linkage of childhood atopic dermatitis to psoriasis susceptibility loci. Nat Genet 27:372-373
16. Devlin B, Risch N (1995) A comparision of linkage disequilibrium measures for fine-scale mapping. Genomics 29:311-322
17. Dziarski R, Platt KA, Gelius E, Steiner H, Gupta D (2003) Defect in neutrophil killing and increase susceptibility to infection with nonpathogenic gram-positive bacteria in peptidoglycan recognition protein-S (PGRP-S)-deficient mice. Blood 102:689-697
18. Eckert RL, Broome AM, Ruse M, Robinson N, Ryan D, Lee K (2004) S100 proteins in the epidermis. J Invest Dermatol 123:23-33
19. Fukuoka M, Ogino Y, Sato H, Ohta T, Komoriya K, Nishioka K, Katayama I (1998) RANTES expression in psoriatic skin, and regulation of RANTES and IL-8 production in cultured epidermal keratinocytes by active vitamin D3 (tacalcitol). Br J Dermatol 138:63-70
20. Gelius E, Persson CP, Karlsson J, Steiner H (2003) A mammalian peptidoglycan recognition protein with N-acetylmramoyl-L-alanine amidase activity. Biochem Biophys Res Commun 306:988-994
21. Guan R, Malchiodi EL, Wang Q, Schuck P, Mariuzza RA (2004) Crystal structure of the C-terminal peptidoglycan-binding domain of human peptidoglycan recognition protein Ialpha. J Biol Chem 279:31873-31882
22. Heizmann CW, Fritz G, Schafer BW (2002) S100 proteins: Structure, functions and pathology. Front Biosci 7:d1356-d1368
23. Hugot JP, Chamaillard M, Zouali H, Lesage S, Cezard JP, Belaiche J, Almer S, Tysk C, O'Mourain CA, Gassull M, Binder V, Finkel Y, Cortot A, Modigliani R, Laurent-Puig P, Gower-Rousseau C, Macry J, Colombel JF, Sahbatou M, Thomas G (2001) Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature 411:599-603
24. Inohara N, Nunez G (2003) NODs: Intracellular proteins involved in inflammation and apoptosis. Nat Rev Immunology 3:371-382
25. Kaneko T, Silverman N (2005) Bacterial recognition and signalling by the Drosophila IMD pathway. Cell Microbiol 7:461-469
26. Kaneko T, Goldman WE, Mellroth P, Steiner H, Fukase K, Kusumoto S, Harley W, Fox A, Golenbock D, Silverman N (2004) Monomeric and polymeric gram-negative peptidoglycan but not purified LPS stimulate the Drosophila IMD pathway. Immunity 20:637-649
27. Kawai K, Shimura H, Minagawa M, Ito A, Tomiyama K, Ito M (2002) Expression of functional Toll-like receptor 2 on human epidermal keratinocytes. J Dermatol Sci 30:185-194
28. Kibardin AV, Mirkina II, Baranova EV, Zakeyeva IR, Georgiev GP, Kiselev SL (2003) The differentially spliced mouse tagL gene, homolog of tag7/ PGRP gene family in mammals and Drosophila, can recognize Gram-positive and Gram-negative bacterial cell wall independently of T phage lysozyme homology domain. J Mol Biol 326:467-474
29. Kiechl S, Wiedermann CJ, Willeit J (2003) Toll-like receptor 4 and atherogenesis. Ann Med 35:164-171
30. Kilding R, Akil M, Till S, Amos R, Winfield J, Iles MM, Wilson AG (2003) A biologically important single nucleotide polymorphism within the toll-like receptor-4 gene is not associated with rheumatoid arthritis. Clin Exp Rheumatol 21:340-342
31. Laird NM, Horvath S, Xu X (2000) Implementing a unified approach to family based tests of association. Genet Epidemiol 19(Suppl 1):S36-S42 S36-S42
32. Liu C, Xu Z, Gupta D, Dziarski R (2001) Peptidoglycan recognition proteins: A novel family of four human innate immunity pattern recognition molecules. J Biol Chem 276:34686-34694
33. Marenholz I, Zirra M, Fischer DF, Backendorf C, Ziegler A, Mischke D (2001) Identification of human epidermal differentiation complex (EDC)-encoded genes by subtractive hybridization of entire YACs to a gridded keratinocyte cDNA library. Genome Res 11:341-355
34. Mathur P, Murray B, Crowell T, Gardner H, Allaire N, Hsu YM, Thill G, Carulli JP (2004) Murine peptidoglycan recognition proteins PglyrpIalpha and PglyrpIbeta are encoded in the epidermal differentiation complex and are expressed in epidermal and hematopoietic tissues. Genomics 83:1151-1163
35. Mellroth P, Karlsson J, Steiner H (2003) A scavenger function for a Drosophila peptidoglycan recognition protein. J Biol Chem 278:7059-7064
36. Michel T, Reichhart JM, Hoffmann JA, Royet J (2001) Drosophila toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein. Nature 414:756-759
37. Mischke D, Korge BP, Marenholz I, Volz A, Ziegler A (1996) Genes encoding structural proteins of epidermal cornification and S100 calcium-binding proteins form a gene complex ("epidermal differentiation complex") on human chromosome 1q21. J Invest Dermatol 106:989-992
38. Nacken W, Roth J, Sorg C, Kerkhoff C (2003) S100A9/S100A8: Myeloid representatives of the S100 protein family as prominent players in innate immunity. Microsc Res Tech 60:569-580
39. Nickoloff BJ, Nestle FO (2004) Recent insights into the immunopathogenesis of psoriasis provide new therapeutic opportunities. J Clin Invest 113:1664-1675
40. Ogura Y, Bonen DK, Inohara N, Nicolae DL, Chen FF, Ramos R, Britton H, Moran T, Karaliuskas R, Duerr RH, Achkar JP, Brant SR, Bayless TM, Kirschner BS, Hanauer SB, Nunez G, Cho JH (2001) A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature 411:603-606
41. Ohta Y, Hamada Y, Katsuoka K (2001) Expression of IL-18 in psoriasis. Arch Dermatol Res 293:334-342
42. Pivarcsi A, Bodai L, Rethi B, Kenderessy-Szabo A, Koreck A, Szell M, Beer Z, Bata-Csorgoo Z, Magocsi M, Rajnavolgyi E, Dobozy A, Kemeny L (2003) Expression and function of Toll-like receptors 2 and 4 in human keratinocytes. Int Immunol 15:721-730
43. Radstake TR, Franke B, Hanssen S, Netea MG, Welsing P, Barrera P, Joosten LA, van Riel PL, van den Berg WB (2004) The Toll-like receptor 4 Asp299Gly functional variant is associated with decreased rheumatoid arthritis disease susceptibility but does not influence disease severity and/or outcome. Arthritis Rheum 50:999-1001
44. Rakoff-Nahoum S, Paglino J, Eslami-Varzaneh F, Edberg S, Medzhitov R (2004) Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis. Cell 118:229-241
45. Rose NR (1998) The role of infection in the pathogenesis of autoimmune disease. Semin Immunol 10:5-13
46. Sanchez E, Orozco G, Lopez-Nevot MA, Jimenez-Alonso J, Martin J (2004) Polymorphisms of toll-like receptor 2 and 4 genes in rheumatoid arthritis and systemic lupus erythematosus. Tissue Antigens 63:54-57
47. Schaid DJ (1996) General score tests for associations of genetic markers with disease using cases and their parents. Genet Epidemiol 13:423-449
48. Schmitt J, Wozell G (2005) The psoriasis area and severity index is the adequate criterion to define severity in chronic plaque-type psoriasis. Dermatology 210:194-199
49. Schroder JM (1999) Epithelial antimicrobial peptides: Innate local host response elements. Cell Mol Life Sci 56:32-46
50. Semprini S, Capon F, Bovolenta S, Bruscia E, Pizzuti A, Fabrizi G, Schietroma C, Zambruno G, Dallapiccola B, Novelli G (1999) Genomic structure, promoter characterisation and mutational analysis of the S100A7 gene: Exclusion of a candidate for familial psoriasis susceptibility. Hum Genet 104:130-134
51. Stoll SW, Chia NV, Nair RP, Woods TL, Stuart P, Henseler T, Jenisch S, Christophers E, Voorhees JJ, Elder JT (2001) S100A2 coding sequence polymorphism: Characterization and lack of association with psoriasis. Clin Exp Dermatol 26:79-83
52. Speckman RA, Wright-Daw JA, Helms C, Duan S, Cau L, Taillon-Miller P, Kwok PY, Menter A, Bowcock AM (2003) Novel immunoglobulin superfamily gene cluster, mapping to a region of human chromosome 17q25, linked to psoriasis susceptibility. Hum Genet 112:34-41
53. Tanji T, Ip YT (2005) Regulators of the Toll and Imd pathways in the Drosophila innate immune response. Trends Immunol 26:193-198
54. Volz A, Korge BP, Compton JG, Ziegler A, Steinert PM, Mischke D (1993) Physical mapping of a functional cluster of epidermal differentiation genes on chromosome 1q21. Genomics 18:92-99
55. Wang ZM, Li X, Cocklin RR, Wang M, Fukase K, Inamura S, Kusumoto S, Gupta D, Dziarski R (2003) Human peptidoglycan recognition protein-l is an N-acetylmuramoyl-l-alanine amidase. J Biol Chem 278:49044-49052
56. Weisenseel P, Laumbacher B, Besgen P, Ludolph-Hauser D, Herzinger T, Roecken M, Wank R, Prinz JC (2002) Streptococcal infection distinguishes different types of psoriasis. J Med Genet 39:767-768
57. Werner T, Liu G, Kang D, Ekengren S, Steiner H, Hultmark D (2000) A family of peptidoglycan recognition proteins in the fruitfly Drosophila melanogaster. Proc Natl Acad Sci USA 97:13772-13777
58. Zenz R, Eferl R, Kenner L, Florin L, Hummerich L, Mehic D, Scheuch H, Angel P, Tschachler E, Wagner EF (2005) Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun proteins. Nature 437:369-375