The angiotensin II receptor antagonist valsartan inhibits endothelin 1-induced vasoconstriction in the skin microcirculation in humans in vivo: Influence of the G-protein β3 subunit (GNB3) C825T polymorphism

Clinical Pharmacology and Therapeutics

Volumn 79, Issue 3, 2006, Pages 274-281

  Mitchell, Anna ^a   Rushentsova, Uljana ^b   Siffert, Winfried ^b   Philipp, Thomas ^b   Wenzel, Rene R ^b  

^a UNIVERSITY HOSPITAL ESSEN   (Germany)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; ENDOTHELIN 1; G PROTEIN BETA SUBUNIT 3; GUANINE NUCLEOTIDE BINDING PROTEIN BETA SUBUNIT; NORADRENALIN; PLACEBO; UNCLASSIFIED DRUG; VALSARTAN;

ADULT; ALLELE; ANTHROPOMETRY; ARTICLE; BLOOD PRESSURE; CONTROLLED STUDY; DRUG INHIBITION; GENOTYPE; HUMAN; HUMAN EXPERIMENT; IN VIVO STUDY; LASER DOPPLER FLOWMETRY; MALE; MICROCIRCULATION; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN POLYMORPHISM; VASOCONSTRICTION;

ADULT; ANGIOTENSIN II; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; BLOOD PRESSURE; CROSS-OVER STUDIES; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; ENDOTHELIN-1; GENOTYPE; HETEROTRIMERIC GTP-BINDING PROTEINS; HUMANS; LASER-DOPPLER FLOWMETRY; MALE; MICROCIRCULATION; NOREPINEPHRINE; POLYMORPHISM, GENETIC; REGIONAL BLOOD FLOW; SKIN; TETRAZOLES; VALINE; VASOCONSTRICTION; VASOCONSTRICTOR AGENTS;

EID: 33644505762     PISSN: 00099236     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clpt.2005.11.008     Document Type: Article

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