메뉴 건너뛰기




Volumn 172, Issue 5, 2006, Pages 771-782

Genetic ablation of zyxin causes Mena/VASP mislocalization, increased motility, and deficits in actin remodeling

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; INTEGRIN; MYOSIN ADENOSINE TRIPHOSPHATASE; VASODILATOR STIMULATED PHOSPHOPROTEIN; ZYXIN;

EID: 33644503878     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200512115     Document Type: Article
Times cited : (137)

References (44)
  • 4
    • 0032411699 scopus 로고    scopus 로고
    • Spatial control of actin filament assembly: Lessons from Listeria
    • Beckerle, M. 1998. Spatial control of actin filament assembly: lessons from Listeria. Cell. 95:741-748.
    • (1998) Cell , vol.95 , pp. 741-748
    • Beckerle, M.1
  • 5
    • 0035858878 scopus 로고    scopus 로고
    • Nascent focal adhesions are responsible for the generation of strong propulsive forces in migrating fibroblasts
    • Beningo, K.A., M. Dembo, I. Kaverina, J.V. Small, and Y.L. Wang. 2001. Nascent focal adhesions are responsible for the generation of strong propulsive forces in migrating fibroblasts. J. Cell Biol. 153:881-888.
    • (2001) J. Cell Biol. , vol.153 , pp. 881-888
    • Beningo, K.A.1    Dembo, M.2    Kaverina, I.3    Small, J.V.4    Wang, Y.L.5
  • 6
    • 0029761645 scopus 로고    scopus 로고
    • The focal-adhesion vasodilator-stimulated phosphoprotein (VASP) binds to the proline-rich domain in vinculin
    • Brindle, N.P., M.R. Holt, J.E. Davies, C.J. Price, and D.R. Critchley. 1996. The focal-adhesion vasodilator-stimulated phosphoprotein (VASP) binds to the proline-rich domain in vinculin. Biochem. J. 318:753-757.
    • (1996) Biochem. J. , vol.318 , pp. 753-757
    • Brindle, N.P.1    Holt, M.R.2    Davies, J.E.3    Price, C.J.4    Critchley, D.R.5
  • 7
    • 0034681423 scopus 로고    scopus 로고
    • Effects of jasplakinolide on the kinetics of actin polymerization. An explanation for certain in vivo observations
    • Bubb, M.R., I. Spector, B.B. Beyer, and K.M. Fosen. 2000. Effects of jasplakinolide on the kinetics of actin polymerization. An explanation for certain in vivo observations. J. Biol. Chem. 275:5163-5170.
    • (2000) J. Biol. Chem. , vol.275 , pp. 5163-5170
    • Bubb, M.R.1    Spector, I.2    Beyer, B.B.3    Fosen, K.M.4
  • 8
    • 0033570095 scopus 로고    scopus 로고
    • Mammal-specific, ERK-dependent, caldesmon phosphorylation in smooth muscle. Quantitation using novel anti-phosphopeptide antibodies
    • D'Angelo, G., P. Graceffa, C.A. Wang, J. Wrangle, and L.P. Adam. 1999. Mammal-specific, ERK-dependent, caldesmon phosphorylation in smooth muscle. Quantitation using novel anti-phosphopeptide antibodies. J. Biol. Chem. 274:30115-30121.
    • (1999) J. Biol. Chem. , vol.274 , pp. 30115-30121
    • D'Angelo, G.1    Graceffa, P.2    Wang, C.A.3    Wrangle, J.4    Adam, L.P.5
  • 9
    • 0033611140 scopus 로고    scopus 로고
    • Molecular dissection of zyxin function reveals its involvement in cell motility
    • Drees, B.E., K.M. Andrews, and M.C. Beckerle. 1999. Molecular dissection of zyxin function reveals its involvement in cell motility. J. Cell Biol. 147:1549-1560.
    • (1999) J. Cell Biol. , vol.147 , pp. 1549-1560
    • Drees, B.E.1    Andrews, K.M.2    Beckerle, M.C.3
  • 10
    • 0034698083 scopus 로고    scopus 로고
    • Characterization of the interaction between zyxin and members of the Ena/Vasodilator-stimulated phosphoprotein family of proteins
    • Drees, B., E. Friederich, J. Fradelizi, D. Louvard, M.C. Beckerle, and R.M. Golsteyn. 2000. Characterization of the interaction between zyxin and members of the Ena/Vasodilator-stimulated phosphoprotein family of proteins. J. Biol. Chem. 275:22503-22511.
    • (2000) J. Biol. Chem. , vol.275 , pp. 22503-22511
    • Drees, B.1    Friederich, E.2    Fradelizi, J.3    Louvard, D.4    Beckerle, M.C.5    Golsteyn, R.M.6
  • 12
    • 0345803932 scopus 로고    scopus 로고
    • PINCH-1 is an obligate partner of integrin-linked kinase (ILK) functioning in cell shape modulation, motility, and survival
    • Fukuda, T., K. Chen, X. Shi, and C. Wu. 2003. PINCH-1 is an obligate partner of integrin-linked kinase (ILK) functioning in cell shape modulation, motility, and survival. J. Biol. Chem. 278:51324-51333.
    • (2003) J. Biol. Chem. , vol.278 , pp. 51324-51333
    • Fukuda, T.1    Chen, K.2    Shi, X.3    Wu, C.4
  • 13
    • 0030592559 scopus 로고    scopus 로고
    • Mena, a relative of VASP and Drosophila Enabled, is implicated in the control of microfilament dynamics
    • Gertler, F.B., K. Niebuhr, M. Reinhard, J. Wehland, and P. Soriano. 1996. Mena, a relative of VASP and Drosophila Enabled, is implicated in the control of microfilament dynamics. Cell. 87:227-239.
    • (1996) Cell , vol.87 , pp. 227-239
    • Gertler, F.B.1    Niebuhr, K.2    Reinhard, M.3    Wehland, J.4    Soriano, P.5
  • 14
    • 0030828053 scopus 로고    scopus 로고
    • Structural and functional similarities between the human cytoskeletal protein zyxin and the ActA protein of Listeria monocytogenes
    • Golsteyn, R.M., M.C. Beckerle, T. Koay, and E. Friederich. 1997. Structural and functional similarities between the human cytoskeletal protein zyxin and the ActA protein of Listeria monocytogenes. J. Cell Sci. 110:1893-1906.
    • (1997) J. Cell Sci. , vol.110 , pp. 1893-1906
    • Golsteyn, R.M.1    Beckerle, M.C.2    Koay, T.3    Friederich, E.4
  • 15
    • 17044369958 scopus 로고    scopus 로고
    • Specific disruption of smooth muscle caldesmon expression in mice
    • Guo, H., and C.L. Wang. 2005. Specific disruption of smooth muscle caldesmon expression in mice. Biochem. Biophys. Res. Commun. 330:1132-1137.
    • (2005) Biochem. Biophys. Res. Commun. , vol.330 , pp. 1132-1137
    • Guo, H.1    Wang, C.L.2
  • 16
    • 0035694237 scopus 로고    scopus 로고
    • Identification of essential genes in cultured mammalian cells using small interfering RNAs
    • Harborth, J., S.M. Elbashir, K. Bechert, T. Tuschl, and K. Weber. 2001. Identification of essential genes in cultured mammalian cells using small interfering RNAs. J. Cell Sci. 114:4557-4565.
    • (2001) J. Cell Sci. , vol.114 , pp. 4557-4565
    • Harborth, J.1    Elbashir, S.M.2    Bechert, K.3    Tuschl, T.4    Weber, K.5
  • 21
    • 0029981428 scopus 로고    scopus 로고
    • Differentiation of the immortalized adult neuronal progenitor cell line HC2S2 into neurons by regulatable suppression of the v-myc oncogene
    • Hoshimaru, M., J. Ray, D.W. Sah, and F.H. Gage. 1996. Differentiation of the immortalized adult neuronal progenitor cell line HC2S2 into neurons by regulatable suppression of the v-myc oncogene. Proc. Natl. Acad. Sci. USA. 93:1518-1523.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 1518-1523
    • Hoshimaru, M.1    Ray, J.2    Sah, D.W.3    Gage, F.H.4
  • 23
    • 0034114114 scopus 로고    scopus 로고
    • Physical state of the extracellular matrix regulates the structure and molecular composition of cell-matrix adhesions
    • Katz, B.Z., E. Zamir, A. Bershadsky, Z. Kam, K.M. Yamada, and B. Geiger. 2000. Physical state of the extracellular matrix regulates the structure and molecular composition of cell-matrix adhesions. Mol. Biol. Cell. 11:1047-1060.
    • (2000) Mol. Biol. Cell , vol.11 , pp. 1047-1060
    • Katz, B.Z.1    Zamir, E.2    Bershadsky, A.3    Kam, Z.4    Yamada, K.M.5    Geiger, B.6
  • 26
    • 0030864520 scopus 로고    scopus 로고
    • A novel proline-rich motif present in ActA of Listeria monocytogenes and cytoskeletal proteins is the ligand for the EVH1 domain, a protein module present in the Ena/VASP family
    • Niebuhr, K., F. Ebel, R. Frank, M. Reinhard, E. Domann, U.D. Carl, U. Walter, F.B. Gertler, J. Wehland, and T. Chakraborty. 1997. A novel proline-rich motif present in ActA of Listeria monocytogenes and cytoskeletal proteins is the ligand for the EVH1 domain, a protein module present in the Ena/VASP family. EMBO J. 16:5433-5444.
    • (1997) EMBO J. , vol.16 , pp. 5433-5444
    • Niebuhr, K.1    Ebel, F.2    Frank, R.3    Reinhard, M.4    Domann, E.5    Carl, U.D.6    Walter, U.7    Gertler, F.B.8    Wehland, J.9    Chakraborty, T.10
  • 27
    • 0030967789 scopus 로고    scopus 로고
    • Nuclear-cytoplasmic shuttling of the focal contact protein, zyxin: A potential mechanism for communication between sites of cell adhesion and the nucleus
    • Nix, D.A., and M.C. Beckerle. 1997. Nuclear-cytoplasmic shuttling of the focal contact protein, zyxin: a potential mechanism for communication between sites of cell adhesion and the nucleus. J. Cell Biol. 138:1139-1147.
    • (1997) J. Cell Biol. , vol.138 , pp. 1139-1147
    • Nix, D.A.1    Beckerle, M.C.2
  • 30
    • 0028854845 scopus 로고
    • Caldesmon mRNA splicing and isoform expression in mammalian smooth-muscle and non-muscle tissues
    • Payne, A.M., P. Yue, K. Pritchard, and S.B. Marston. 1995. Caldesmon mRNA splicing and isoform expression in mammalian smooth-muscle and non-muscle tissues. Biochem. J. 305:445-450.
    • (1995) Biochem. J. , vol.305 , pp. 445-450
    • Payne, A.M.1    Yue, P.2    Pritchard, K.3    Marston, S.B.4
  • 32
    • 0036469131 scopus 로고    scopus 로고
    • Doing (F/L)PPPPs: EVH1 domains and their proline-rich partners in cell polarity and migration
    • Renfranz, P.J., and M.C. Beckerle. 2002. Doing (F/L)PPPPs: EVH1 domains and their proline-rich partners in cell polarity and migration. Curr. Opin. Cell Biol. 14:88-103.
    • (2002) Curr. Opin. Cell Biol. , vol.14 , pp. 88-103
    • Renfranz, P.J.1    Beckerle, M.C.2
  • 33
    • 0035162704 scopus 로고    scopus 로고
    • Zyxin is not colocalized with vasodilator-stimulated phosphoprotein (VASP) at lamellipodial tips and exhibits different dynamics to vinculin, paxillin, and VASP in focal adhesions
    • Rottner, K., M. Krause, M. Gimona, J.V. Small, and J. Wehland. 2001. Zyxin is not colocalized with vasodilator-stimulated phosphoprotein (VASP) at lamellipodial tips and exhibits different dynamics to vinculin, paxillin, and VASP in focal adhesions. Mol. Biol. Cell. 12:3103-3113.
    • (2001) Mol. Biol. Cell , vol.12 , pp. 3103-3113
    • Rottner, K.1    Krause, M.2    Gimona, M.3    Small, J.V.4    Wehland, J.5
  • 34
    • 0029257376 scopus 로고
    • The MyoD family of transcription factors and skeletal myogenesis
    • Rudnicki, M.A., and R. Jaenisch. 1995. The MyoD family of transcription factors and skeletal myogenesis. Bioessays. 17:203-209.
    • (1995) Bioessays , vol.17 , pp. 203-209
    • Rudnicki, M.A.1    Jaenisch, R.2
  • 37
    • 0035749892 scopus 로고    scopus 로고
    • Caldesmon and smooth-muscle regulation
    • Wang, C.L. 2001. Caldesmon and smooth-muscle regulation. Cell Biochem. Biophys. 35:275-288.
    • (2001) Cell Biochem. Biophys. , vol.35 , pp. 275-288
    • Wang, C.L.1
  • 38
    • 17844395749 scopus 로고    scopus 로고
    • Analysis of methylation-sensitive transcriptome identifies GADD45a as a frequently methylated gene in breast cancer
    • Wang, W., G. Huper, Y. Guo, S.K. Murphy, J.A. Olson, and J.R. Marks. 2005. Analysis of methylation-sensitive transcriptome identifies GADD45a as a frequently methylated gene in breast cancer. Oncogene. 24:2705-2714.
    • (2005) Oncogene , vol.24 , pp. 2705-2714
    • Wang, W.1    Huper, G.2    Guo, Y.3    Murphy, S.K.4    Olson, J.A.5    Marks, J.R.6
  • 39
    • 0031929760 scopus 로고    scopus 로고
    • Vinculin knockout results in heart and brain defects during embryonic development
    • Xu, W., H. Baribault, and E.D. Adamson. 1998. Vinculin knockout results in heart and brain defects during embryonic development. Development. 125:327-337.
    • (1998) Development , vol.125 , pp. 327-337
    • Xu, W.1    Baribault, H.2    Adamson, E.D.3
  • 40
    • 0032522147 scopus 로고    scopus 로고
    • The human TRIP6 gene encodes a LIM domain protein and maps to chromosome 7q22, a region associated with tumorigenesis
    • Yi, J., and M.C. Beckerle. 1998. The human TRIP6 gene encodes a LIM domain protein and maps to chromosome 7q22, a region associated with tumorigenesis. Genomics. 49:314-316.
    • (1998) Genomics , vol.49 , pp. 314-316
    • Yi, J.1    Beckerle, M.C.2
  • 41
    • 27544435992 scopus 로고    scopus 로고
    • Mechanical force mobilizes zyxin from focal adhesions to actin filaments and regulates cytoskeletal reinforcement
    • Yoshigi, M., L.M. Hoffman, C.C. Jensen, H.J. Yost, and M.C. Beckerle. 2005. Mechanical force mobilizes zyxin from focal adhesions to actin filaments and regulates cytoskeletal reinforcement. J. Cell Biol. 171:209-215.
    • (2005) J. Cell Biol. , vol.171 , pp. 209-215
    • Yoshigi, M.1    Hoffman, L.M.2    Jensen, C.C.3    Yost, H.J.4    Beckerle, M.C.5
  • 42
    • 0344465841 scopus 로고    scopus 로고
    • Early molecular events in the assembly of matrix adhesions at the leading edge of migrating cells
    • Zaidel-Bar, R., C. Ballestrem, Z. Kam, and B. Geiger. 2003. Early molecular events in the assembly of matrix adhesions at the leading edge of migrating cells. J. Cell Sci. 116:4605-4613.
    • (2003) J. Cell Sci. , vol.116 , pp. 4605-4613
    • Zaidel-Bar, R.1    Ballestrem, C.2    Kam, Z.3    Geiger, B.4
  • 44
    • 2442650463 scopus 로고    scopus 로고
    • Differential expression of splicing variants of the human caldesmon gene (CALD1) in glioma neovascularization versus normal brain microvasculature
    • Zheng, P.P., A.M. Sieuwerts, T.M. Luider, M. van der Weiden, P.A. Sillevis-Smitt, and J.M. Kros. 2004. Differential expression of splicing variants of the human caldesmon gene (CALD1) in glioma neovascularization versus normal brain microvasculature. Am. J. Pathol. 164:2217-2228.
    • (2004) Am. J. Pathol. , vol.164 , pp. 2217-2228
    • Zheng, P.P.1    Sieuwerts, A.M.2    Luider, T.M.3    Van Der Weiden, M.4    Sillevis-Smitt, P.A.5    Kros, J.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.