Is there a place for immunomodulation in assisted reproduction techniques?

Journal of Reproductive Immunology

Volumn 62, Issue 1-2, 2004, Pages 29-39

  Chaouat, Gerard ^a   Ledee bataill, Natalie ^a   Dubanchet, Sylvie ^a  

^a HÔPITAL ANTOINE BÉCLÈRE   (France)

Author keywords

Abortion; Immunotherapy; Implantation concepts revision

Indexed keywords

ADOPTIVE IMMUNOTHERAPY; ALLOIMMUNIZATION; BIOSAFETY; CELL ACTIVITY; CELL FUNCTION; CONFERENCE PAPER; HISTORY; HUMAN; IMMUNOMODULATION; IMMUNOTHERAPY; INFERTILITY THERAPY; LYMPHOCYTE; MOTHER FETUS RELATIONSHIP; PRIORITY JOURNAL; SPONTANEOUS ABORTION; TH1 CELL; TH2 CELL; TREATMENT INDICATION;

ABORTION, SPONTANEOUS; FEMALE; HUMANS; IMMUNOLOGIC FACTORS; IMMUNOTHERAPY; PREGNANCY; REPRODUCTIVE TECHNIQUES, ASSISTED; T-LYMPHOCYTES, HELPER-INDUCER;

EID: 3343022510     PISSN: 01650378     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jri.2003.09.005     Document Type: Conference Paper

References (62)

1. Ashkar A.A., Di Santo J.P., Croy B.A. Interferon gamma contributes to initiation of uterine vascular modification, decidual integrity, and uterine natural killer cell maturation during normal murine pregnancy. J. Exp. Med. 192:2000;259-270
2. Athanassakis I., Chaouat G., Wegmann T.G. The effects of anti-CD4 and anti-CD8 antibody treatment on placental growth and function in allogeneic and syngeneic pregnancy. Cell. Immunol. 129:1990;13-21
3. Barber E.M., Pollard J.W. The uterine NK cell population requires IL-15 but these cells are not required for pregnancy nor the resolution of a Listeria monocytogenes infection. J. Immunol. 171:2003;37-46
4. Beer A.E., Billingham R.E. Maternal immunological recognition mechanisms during pregnancy. Ciba Found. Symp. 64:1978;293-322
5. Beer A.E., Quebbeman J.F., Ayers J.W., Haines R.F. Major histocompatibility complex antigens, maternal and paternal immune responses, and chronic habitual abortions in humans. Am. J. Obstet. Gynecol. 141:1981;987-999
6. Buy-Quang D., Soulillou J.P., Fontenaille C., Guimbretiere J., Guenel J. The beneficial role of blood transfusion and pregnancy in the survival of renal allografts. Nouvelle Presse Med. 6:1977;3503-3507
7. Cadavid A., Pena B., Garcia G., Botero J., Sanchez F., Ossa J., Beer A. Heparin plus aspirin as a "single" therapy for recurrent spontaneous abortion associated with both allo- and autoimmunity. Am. J. Reprod. Immunol. 41:1999;271-278
8. Chaouat G., Kiger N., Wegmann T.G. Vaccination against spontaneous abortion in mice. J. Reprod. Immunol. 5:1983;389-392
9. Chaouat G., Assal-Meliani A., Martal J., Raghupathy R., Elliot J., Mosmann T., Wegmann T.G. IL-10 prevents naturally occurring fetal loss in the CBA × DBA/2 mating combination, and local defect in IL-10 production in this abortion-prone combination is corrected by in vivo injection of IFN-tau. J. Immunol. 154:1995;4261-4268
10. Chaouat G., Lédée-Bataille N., Zourbas S., Ostojic S., Dubanchet S., Martal J., Frydman R. Cytokines, implantation and early abortion: re-examining the Th1/Th2 paradigm leads to question the single pathway, single therapy concept. Am. J. Reprod. Immunol. 50:2003;177-186
11. Christiansen O.B., Pedersen B., Regard A., Hush M. A randomised randomised double blind, placebo-controlled trial of intravenous immunoglobulin in the prevention of recurrent miscarriage: evidence for a therapeutic effect in women with secondary recurrent miscarriage. Hum. Reprod. 17:2002;809-816
12. Christiansen O.B., Nielsen H.S., Pedersen B. Active or passive immunisation in unexplained recurrent miscarriage. J. Reprod. Immunol. 62:2004;41-52
13. Clark D.A., Banwatt D., Chaouat G. Stress-triggered abortion in mice is prevented by alloimmunisation. Am. J. Reprod. Immunol. 29:1993;141-148
14. Clark D.A., Gorzynski R.M., Levy G.A. Not Th1 nor Th2, but "danger" for whom the belle tolls. Am J. Reprod. Immunol. 48:2002;140
15. The recurrent miscarriage immunotherapy trialists group, 1994. Worldwide collaborative observational study and metanalysis on allogeneic leukocyte therapy for recurrent spontaneous abortion. Am. J. Reprod. Immunol. 32, 55-72
16. Croy B.A., Ashkar A.A., Minhas K., Greenwood J.D. Can murine uterine natural killer cells give insights into the pathogenesis of pre eclampsia? J. Soc. Gynecol. Investig. 7:2001;12-20
17. Croy B.A., Esadeg S., Chantakru S., Van den Heuvel M., Paffaro V.A., He H., Black G.P., Ashkar A.A., Kiso Y., Zhang J. Update on pathways regulating the activation of uterine natural killer cells, their interactions with decidual spiral arteries and homing of their precursors to the uterus. J. Reprod. Immunol. 59:2003;175-191
18. Daya S., Gunby J., Clark D.A. Intravenous immunoglobulin therapy for recurrent spontaneous abortion: a meta-analysis. Am. J. Reprod. Immunol. 39:1998;69-76
19. Delage G., Moreau J.-F., Taupin J.-L., Freitas S., Hambartsoumian E., Olivennes F., Fanchin R., Letut-Körnish H., Fydman R., Chaouat G. In vitro endometrial secretion of human interleukin for DA cells/leukaemia inhibitory factor by explant cultures from fertile and infertile women. Hum. Reprod. 10:1995;2483-2488
20. Fallon P.G., Jolin H.E., Smith P., Emson C.L., Townsend M.J., Fallon R., Smith P., McKenzie A.N. IL-4 induces characteristic Th2 responses even in the combined absence of IL-5, IL-9 and IL-13. Immunity. 17:2002;7-17
21. Faulk W.P., Temple A., Lovins R.E., Smith N. Antigens of human trophoblasts: a working hypothesis for their role in normal and abnormal pregnancies. Proc. Natl. Acad. Sci. U.S.A. 75:1978;1947-1951
22. Giess R., Tanasescu I., Steck T., Sendtner M. Leukaemia inhibitory factor gene mutations in infertile women. Mol. Hum. Reprod. 6:1999;581-586
23. Gor D.O., Rose N.R., Greenspan N.S. Th1-Th2: a procrustean paradigm. Nat. Immunol. 4:2003;503-505
24. Guimond M.J., Wang B., Croy B.A. Engraftment of bone marrow from severe combined immunodeficiency (SCID) mice reverses the reproductive deficit in natural killer cell deficient TgE26 mice. J. Exp. Med. 187:1998;217-223
25. Hill, J.A., 1997. Immunotherapy for recurrent pregnancy loss: "standard of care or buyer beware". J. Soc. Gynecol. Invest. 267-273.
26. Hunt J.S., Hua Lin C., Miller L. Tumor necrosis factors: pivotal components of pregnancy? Biol. Reprod. 54:1996;554-563
27. Johnson, P.M., Risk, J.M., Mwenda, J.M., Hart, C.A., Purcell, D.F.J., Deacon, N.J., 1989. Human trophoblast expression of retroviral like activity and CD 46 (membrane cofactor protein [MCP], HuLy-m5 and H316 [TLX] antigen). In: Mettler, L., Billington, W.D. (Eds.), Reproductive Immunology, Amsterdam, pp. 169-177.
28. Kelly P.A., Binart N., Lucas B., Bouchard B., Goffin V. Implications of multiple phenotypes observed in prolactin receptor knockout mice. Front. Neuroendocrinol. 22:2001;140-145
29. Kelso, A., Th1 and Th2 subsets: paradigms lost? Immunol. Today 16, 374-379
30. Krishnan L., Guilbert L.J., Wegmann T.G., Belosevic M., Mossman T.R. Helper 1 response against Leishmania major in pregnant C57BL/6 mice increases implantation failure and fetal resorption (1995) correlation with increased IFN-γ and TNF and reduced IL-10 production by placental cells. J. Immunol. 156:1996a;653-662
31. Krishnan L., Guilbert L.J., Russell A.S., Wegmann T.J., Mosmann T.R., Belosevic M. Pregnancy impairs resistance of C57Bl/6 mice to Leishmania major infection and causes decreased antigen-specific IFN-γ response and increased production of T helper 2 cytokines. J. Immunol. 156:1996;644-653
32. Kwak J.Y., Beer A.E., Kim S.H., Mantouvalos H.P. Immunopathology of the implantation site utilising monoclonal antibodies to natural killer cells in women with recurrent pregnancy losses. Am. J. Reprod. Immunol. 41:1999;91-98
33. Labarrere C.A., Faulk W.P., McIntyre J.A., Althabe O.H. Materno-trophoblastic immunological balance. Am. J. Reprod. Immunol. 21:1989;16-25
34. Laird S.M., Tuckerman E.M., Dalton C.F., Dunphy B.C., LiI T.C., Zhang X. The production of leukemia inhibitory factor by human endometrium: presence in uterine flushings and production by cells in culture. Hum. Reprod. 12:1997;569-574
35. Ledee Bataille N., Dubanchet S., Bonnet K., Coulomb L'Hermine A., Durand Gasselin I., Frydman R., Chaouat G. A new role for natural killer cells IL-12 and IL-18 in repeated implantation failure. Fertil. Steril. 81:2003;59-65
36. Lin H., Mossmann T.R., Guilbert L., Tuntipopipat S., Wegmann T.G. Synthesis of T helper-2 cytokines at the maternal fetal interface. J. Immunol. 151:1993;4562-4573
37. Lokki M.L., Laitinen T. Role of major histocompatibility complex class III genes in recurrent spontaneous abortions. Front. Biosci. 6:2001;E23-E29
38. Michimata T., Ogasawara M.S., Tsuda H., Suzumori K., Aoki K., Sakai M., Fujimura M., Nagata K., Nakamura M., Saito S. Distribution of endometrial NK cells, B cells, T cells and Th2/Tc2 cells fail to predict pregnancy outcome following recurrent abortion. Am. J. Reprod. Immunol. 47:2002;196-202
39. Miyazaki S., Tanebe K., Sakai M., Michimata T., Tsuda H., Fujimura M., Nakamura M., Kiso Y., Saito S. Interleukin 2 receptor gamma chain (gamma(c)) knockout mice show less regularity in estrous cycle but achieve normal pregnancy without fetal compromise. Am. J. Reprod. Immunol. 47:2002;222-230
40. Mowbray J.F., Lidell H., Underwood J.L., Gibbins C., Reginald P.W., Beard R.W. Controlled trial of treatment of recurrent spontaneous abortions by immunisation with paternal cells. Lancet. i:1985;941-943
41. Munn D.H., Zhou M., Attwood J.T., Bondarev I., Conway S.J., Marshall B., Brown C., Mellor A.L. Prevention of allogeneic fetal rejection by tryptophan catabolism. Science. 2281:1998;1191-1193
42. Ober C., Karrison T., Odem R.R., Barnes R.B., Branch D.W., Stephenson M.D., Baron B., Walker M.A., Scott J.R., Schreiber J.R. Mononuclear-cell immunisation in prevention of recurrent miscarriages: a randomised trial. Lancet. 354:1999;365-369
43. Ostojic S., Dubanchet S., Mjihdi A., Truyens C., Capron F., Chaouat G. Demonstration of the presence of IL-16, IL-17 and IL-18 at the murine fetomaternal interface during murine pregnancy. Am. J. Reprod. Immunol. 49:2003;101-113
44. Plevyak M., Hanna N., Mayer S., Murphy S., Pinar H., Fast L., Ekerfelt C., Ernerudh J., Berg G., Matthiesen L., Sharma S. Deficiency of decidual IL-10 in first trimester missed abortion: lack of correlation with the decidual immune cell profile. Am. J. Reprod. Immunol. 47:2002;242-250
45. Raghupathy R. Th1-type immunity is incompatible with successful pregnancy. Immunol. Today. 18:1997;478-482
46. Raghupathy R., Makhseed M., Azizieh F., Hassan N., Al-Azemi M., Al-Shamali E. Maternal Th1- and Th2-type reactivity to placental antigens in normal human pregnancy and unexplained recurrent spontaneous abortions. Cell Immunol. 196:1999;122-130
47. Robb L., Li R., Hartley L., Nandurkar H., Koetgen F., Begley C.G. Infertility in female mice lacking the receptor for interleukin-11 is due to a defective uterine response to implantation. Nature Med. 4:1998;303-308
48. Sacks G.P., Redman C.W., Sargent I.L. Monocytes are primed to produce the Th1 type cytokine IL-12 in normal human pregnancy: an intracellular flow cytometric analysis of peripheral blood mononuclear cells. Clin. Exp. Immunol. 131:2003;490-497
49. Scott, J.R., 2003. Immunotherapy for recurrent miscarriage. Cochrane Database Syst. Rev. (see Medline).
50. Stewart C., Kaspar P., Brunet L.J., Bhatt H., Gadi I., Köntgen F., Bondanzo S. Blastocyst implantation depends on maternal expression of leukemia inhibitory factor. Nature. 359:1992;76-79
51. Stray-Pedersen B., Stray-Pedersen S. Etiologic factors and subsequent reproductive performance in 195 couples with a prior history of habitual abortion. Am. J. Obstet. Gynecol. 148:1984;140-146
52. Strominger J.L. Human decidual lymphocytes and the immunobiology of pregnancy. J. Reprod. Immunol. 62:2004;17-18
53. Taylor C., Faulk W.P. Prevention of recurrent spontaneous abortions with leukocyte transfusion. Lancet. ii:1981;68-70
54. Terasaki P.I. The beneficial transfusion effect on kidney graft survival attributed to clonal deletion. Transplantation. 37:1984;119-125
55. Thomas, D., Michou, V., Tegos, V., Moustakarias, T., Kanakas, N., Mantzavinos, T., Apostolidis, C., Salamalekis, E.M., Kalofoutis, A., Tsilivakos, V., 2003. The effect of alacyclovir treatment on natural killer cells of infertile women. Am. J. Reprod. Immunol., in press.
56. Toder V., Fein A., Carp H., Torchinsky A. TNF-alpha in pregnancy loss and embryo maldevelopment: a mediator of detrimental stimuli or a protector of the fetoplacental unit? J. Assist. Reprod. Genet. 20:2003;73-81
57. Torchinsky A., Shepshelovich J., Orenstein H., Zaslavsky Z., Savion S., Carp H., Fain A., Toder V. TNF-alpha protects embryos exposed to developmental toxicants. Am. J. Reprod. Immunol. 49:2003;159-168
58. Vince G.S., Johnson P.M. Is there a Th2 bias in human pregnancy? J. Reprod. Immunol. 32:1996;101-104
59. Wegmann T.G. Fetal protection against abortion: is it immunosuppression or immunostimulation ? Ann. Immunol. Inst. Pasteur. 135D:1984;309-311
60. Wegmann T.G., Lin H., Guilbert L., Mossman T.H. Bidirectional cytokines interactions in the materno-fetal relationship: successful allopregnancy is a Th2 phenomenon. Immunol. Today. 14:1993;353-355
61. Xu C., Mao D., Holers M., Palanca B., Cheng A.M., Molina H. A critical role for complement regulatory Crry in feto-maternal tolerance. Science. 287:2000;498-499
62. Zhang, J.H., He, H., Borzychowski, A.M., Takeda, K., Akria, S., Croy, B.A., March 19 2003. Analysis of cytokine regulators inducing interferon-{gamma} production by mouse uterine natural killer cells. Biol. Reprod. 69, 404-411. Epub March 19, 2003.