Role of circulating soluble CD40 as an apoptotic marker in liver disease

Apoptosis

Volumn 9, Issue 2, 2004, Pages 205-210

  Schmilovitz Weiss, H ^a   Belinki, A ^b   Pappo, O ^c   Sulkes, J ^d   Melzer, E ^a   Kaganovski, E ^c   Kfir, B ^a   Tur Kaspa, R ^e   Klein, T ^a   Ben Ari, Z ^a,e  

^a RABIN MEDICAL CENTER   (Israel)

^b Department of Invasive Radiology ^*  (Israel)

^c Epidemiology Unit   (Israel)

^d HLA Typing Laboratory   (Israel)

^e TEL AVIV UNIVERSITY   (Israel)

Author keywords

Apoptosis; CD40; Liver disease; Soluble

Indexed keywords

CD40 ANTIGEN;

ADULT; ALCOHOL LIVER DISEASE; APOPTOSIS; ARTICLE; AUTOIMMUNE HEPATITIS; CHOLESTATIC HEPATITIS; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HEPATIC VEIN; HEPATITIS B; HEPATITIS C; HISTOPATHOLOGY; HUMAN; LABORATORY TEST; LIVER DISEASE; MAJOR CLINICAL STUDY; MALE; NICK END LABELING; PORTAL VEIN; PRIORITY JOURNAL;

ANTIGENS, CD40; APOPTOSIS; BILE; BIOLOGICAL MARKERS; FEMALE; HEPATIC VEINS; HUMANS; IN SITU NICK-END LABELING; LIVER DISEASES; MALE; MIDDLE AGED; PORTAL VEIN;

HEPATITIS C VIRUS;

EID: 3343016618     PISSN: 13608185     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:APPT.0000018802.95600.25     Document Type: Article

References (29)

1. Van Kooten C, Banchereau J. Functions of CD40 on B cells, dendritic cells and other cells. Curr Opin Immunol 1997; 9: 330-337.
2. Lacronique V, Mignon A, Fabre M, et al. Bcl-2 protects from lethal hepatic apoptosis induced by an anti-Fas antibody in mice. Nature Med 1996; 2: 80-86.
3. Ogasawara J, Watanabe-Fukunaga R, Adachi M, et al. Lethal effect of the anti-Fas antibody in mice. [Published erratum appears in Nature (London) 1993;365:568] Nature 1993; 364: 806-809.
4. Kondo T, Suda T, Fukuyama H, Adachi M, Nagata S. Essential roles of the Fas ligand in the development of hepatitis. Nat Med 1997; 3: 409-413.
5. Strand S, Hofmann WJ, Grambihler A, et al. Hepatic failure and liver cell damage in acute Wilson's disease involve CD95 (APO-1/Fas) mediated apoptosis. Nat Med 1998; 4: 588-593.
6. Galle PR, Hofmann WJ, Wlaczak H, et al. Involvement of the CD95 (APO1/FAS) receptor and ligand in liver damage. J Exp Med 1995; 182: 1223-1230.
7. Afford SC, Randhawa S, Eliopoulos AG, Hubscher SG, Young LS, Adams DH. CD40 activation induces apoptosis in cultured human hepatocytes via induction of cell surface fas ligand expression and amplifies fas mediated hepatocyte death during allograft rejection. J Exp Med 1999; 189: 441-446.
8. Eliopoulos AG, Davies C, Knox PG, et al. CD40 induces apoptosis in carcinoma cells through activation of cytotoxic ligands of the tumor necrosis factor superfamily. Mol Cell Biol 2000; 20: 5503-5515.
9. Knodell RG, Ishak KG, Black WC, et al. Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis. Hepatology 1981; 1: 431-435.
10. Gavrieli Y, Sherman Y, Ben-Sasson SA. Identification of programmed cell death m situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 1992; 119: 493-501.
11. Sedivy R, Gollackner B, Casati B, et al. Apoptotic hepatocytes in rejection and vascular occlusion in liver allograft specimens. Histopathology 1998; 32: 503-507.
12. Rust C, Gores GJ. Apoptosis and liver disease. Am J Med 2000; 108: 567-574.
13. Hayashi N, Mita E. Involvement of Fas system-mediated apoptosis in pathogenesis of viral hepatitis. J Viral Hepat 1999; 6: 357-365.
14. Hahn CS, Cho YG, Kang BS, Lester IM, Hahn YS. The HCV core protein acts as a positive regulator of fas-mediated apoptosis in a human lymphoblastoid T cell line. Virology 2000; 276: 127-137.
15. Burgio VL, Ballardini G, Artini M, Caratozzolo M, Bianchi FB, Levrero M. Expression of co-stimulatory molecules by Kupffer cells in chronic hepatitis of hepatitis C etiology. Hepatology 1998; 27: 1600-1606.
16. Oxenius A, Campbell KA, Maliszewski CR, et al. CD40-CD40 ligand interactions are critical in T-B cooperation but not for other anti-viral CD4+ T cell functions. J Exp Med 1996; 183: 2209-2218.
17. Calabrese F, Pontisso P, Pettenazzo E, et al. Liver cell apoptosis in chronic hepatitis C correlates with histological but not biochemical activity or serum HCV-RNA levels. Hepatology 2000; 31: 1153-1159.
18. Faubion WA, Guicciardi ME, Miyoshi H, et al. Toxic bile salts induce rodent hepatocyte apoptosis via direct activation of Fas. J Clin Invest 1999; 103: 137-145.
19. Harada K, Ozaki S, Gerswin MG, Nakanuma Y. Enhanced apoptosis relates to bile duct loss in primary biliary cirrhosis. Hepatology 1997; 26: 1399-1405.
20. Afford SC, Ahmed-Choudhury J, Randhawa S, et al. CD40 activation-induced, Fas-dependent apoptosis and NF kappa B/AP-signaling in human intrahepatic biliary epithelial cells. FASEB J 2001; 15: 2345-2354.
21. Azzaroli F, Mehal W, Soroka CJ, et al. Ursodeoxycholic acid diminishes Fas-ligand-induced apoptosis in mouse hepatocytes. Hepatology 2002; 36: 49-54.
22. Poupon RE, Lindor KD, Cauch-Dudek K, Dickson ER, Poupon R, Heathcote EJ. Combined analysis of randomized controlled trials of ursodeoxycholic acid in primary biliary cirrhosis. Gastroenterology 1997; 113: 884-890.
23. Lindor KD. Ursodiol for primary sclerosing cholangitis, Mayo Primary Sclerosing Cholangitis-Ursodeoxycholic Acid Study Group. N Engl J Med 1997; 336: 691-695.
24. Sugimoto K, Shiraki K, Ito T, et al. Expression of functional CD40 in human hepatocellular carcinoma. Hepatology 1999; 30: 920-926.
25. Jakobson E, Jonsson G, Bjorck P, Paulie S. Stimulation of CD40 in human bladder carcinoma cells inhibits anti-Fas/APO-1 (CD95)-induced apoptosis. Int J Cancer 1998; 77: 849-853.
26. Bergamo A, Bataille R, Pellat-Deceunynck C. CD40 and CD95 induce programmed cell death in the human myeloma cell line XG2. Br J Haematol 1997; 97: 652-625.
27. Rivero M, Crespo J, Faberga E, et al. Apoptosis mediated by the Fas system in the fulminant hepatitis by hepatitis B virus. J Viral Hepat 2002; 9: 107-113.
28. Leifeld L, Trautwein C, Dumoulin FL, Manns MP, Sauerbruch T, Spengler U. Enhanced expression of CD80 (B7-1), CD86 (B7-2), and CD40 and their ligands CD28 and CD154 in fulminant hepatic failure. Am J Pathol 1999; 154: 1711-1720.
29. Bayer EM, Herr W, Kanzler S, et al. Transforming growth factor-beta 1 in autoimmune hepatitis: Correlation of liver tissue expression and serum levels with disease activity. J Hepatol 1998; 28: 803-811.