Attenuation of the bacterial load in blood by pretreatment with granulocyte-colony-stimulating factor protects rats from fatal outcome and brain damage during Streptococcus pneumoniae meningitis

Infection and Immunity

Volumn 72, Issue 8, 2004, Pages 4647-4653

  Brandt, Christian T ^a,c   Lundgren, Jens D ^a   Lund, Søren Peter ^b   Frimodt Møller, Niels ^a   Christensen, Thomas ^b   Benfield, Thomas ^a   Espersen, Frank ^a   Hougaard, David M ^a   Østergaard, Christian ^a  

^a HVIDOVRE HOSPITAL   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c STATENS SERUM INSTITUT   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

CEFTRIAXONE; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; ROCEPHALIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTEREMIA; BACTERIAL MENINGITIS; BRAIN CORTEX; BRAIN INJURY; CEREBROSPINAL FLUID ANALYSIS; CONTROLLED STUDY; DEATH; DISEASE MODEL; HISTOLOGY; HISTOPATHOLOGY; INFECTION PREVENTION; LEUKOCYTE COUNT; MALE; NEUTROPHIL; NONHUMAN; PLEOCYTOSIS; PRIORITY JOURNAL; PROGNOSIS; PROTECTION; RAT; STREPTOCOCCUS PNEUMONIAE; TERMINAL DISEASE; TRAMETES;

ANIMALS; BACTEREMIA; BLOOD; BRAIN; CEREBROSPINAL FLUID; GRANULOCYTE COLONY-STIMULATING FACTOR; HUMANS; MENINGITIS, PNEUMOCOCCAL; PROGNOSIS; RATS; STREPTOCOCCUS PNEUMONIAE;

EID: 3342981170     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.72.8.4647-4653.2004     Document Type: Article

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