-
1
-
-
0016756272
-
Continuous cultures of fused cells secreting antibody of predefined specificity
-
Kohler G. Milstein C. Continuous cultures of fused cells secreting antibody of predefined specificity Nature 256 1975 495-497
-
(1975)
Nature
, vol.256
, pp. 495-497
-
-
Kohler, G.1
Milstein, C.2
-
2
-
-
0018701862
-
Monoclonal antibodies defining distinctive human T cell surface antigens
-
Kung P. Goldstein G. Reinherz E.L. Schlossman S.F. Monoclonal antibodies defining distinctive human T cell surface antigens Science 206 1979 347-349
-
(1979)
Science
, vol.206
, pp. 347-349
-
-
Kung, P.1
Goldstein, G.2
Reinherz, E.L.3
Schlossman, S.F.4
-
3
-
-
0019447825
-
Use of monoclonal antibodies to T-cell subsets for immunologic monitoring and treatment in recipients of renal allografts
-
Cosimi A.B. Colvin R.B. Burton R.C. Rubin R.H. Goldstein G. Kung P.C. Hansen W.P. Delmonico F.L. Russell P.S. Use of monoclonal antibodies to T-cell subsets for immunologic monitoring and treatment in recipients of renal allografts N Engl J Med 305 1981 308-314
-
(1981)
N. Engl. J. Med.
, vol.305
, pp. 308-314
-
-
Cosimi, A.B.1
Colvin, R.B.2
Burton, R.C.3
Rubin, R.H.4
Goldstein, G.5
Kung, P.C.6
Hansen, W.P.7
Delmonico, F.L.8
Russell, P.S.9
-
4
-
-
0021816056
-
A randomized clinical trial of OKT3 monoclonal antibody for acute rejection of cadaveric renal transplants
-
Ortho Multicenter Transplant Study Group
-
Ortho Multicenter Transplant Study Group: A randomized clinical trial of OKT3 monoclonal antibody for acute rejection of cadaveric renal transplants. N Engl J Med 1985, 313 337-342.
-
(1985)
N. Engl. J. Med.
, vol.313
, pp. 337-342
-
-
-
5
-
-
0022544549
-
Prophylactic use of OKT3 monoclonal antibody in cadaver kidney recipients. Utilization of OKT3 as the sole immunosuppressive agent
-
Vigeral P. Chkoff N. Chatenoud L. Campos H. Lacombe M. Droz D. Goldstein G. Bach J.F. Kreis H. Prophylactic use of OKT3 monoclonal antibody in cadaver kidney recipients. Utilization of OKT3 as the sole immunosuppressive agent Transplantation 41 1986 730-733
-
(1986)
Transplantation
, vol.41
, pp. 730-733
-
-
Vigeral, P.1
Chkoff, N.2
Chatenoud, L.3
Campos, H.4
Lacombe, M.5
Droz, D.6
Goldstein, G.7
Bach, J.F.8
Kreis, H.9
-
6
-
-
0000911419
-
T cell antigen receptors
-
Edited by Paul W. New York: Raven Press
-
Davis MM, Chien YH: T cell antigen receptors. In Fundamental Immunology. Edited by Paul W. New York: Raven Press; 1999 341-366.
-
(1999)
Fundamental Immunology
, pp. 341-366
-
-
Davis, M.M.1
Chien, Y.H.2
-
7
-
-
0018836897
-
OKT3: A monoclonal anti-human T lymphocyte antibody with potent mitogenic properties
-
Van Wauwe J.P. De Mey J.R. Goossens J.G. OKT3: a monoclonal anti-human T lymphocyte antibody with potent mitogenic properties J Immunol 124 1980 2708-2713
-
(1980)
J. Immunol.
, vol.124
, pp. 2708-2713
-
-
Van Wauwe, J.P.1
De Mey, J.R.2
Goossens, J.G.3
-
8
-
-
0026101638
-
Corticosteroid inhibition of the OKT3-induced cytokine-related syndrome-dosage and kinetics prerequisites
-
Chatenoud L. Legendre C. Ferran C. Bach J.F. Kreis H. Corticosteroid inhibition of the OKT3-induced cytokine-related syndrome-dosage and kinetics prerequisites Transplantation 51 1991 334-338
-
(1991)
Transplantation
, vol.51
, pp. 334-338
-
-
Chatenoud, L.1
Legendre, C.2
Ferran, C.3
Bach, J.F.4
Kreis, H.5
-
9
-
-
0024554613
-
Release of tumor necrosis factor, interleukin-2, and gamma-interferon in serum after injection of OKT3 monoclonal antibody in kidney transplant recipients
-
Abramowicz D. Schandene L. Goldman M. Crusiaux A. Vereerstraeten P. De Pauw L. Wybran J. Kinnaert P. Dupont E. Toussaint C. Release of tumor necrosis factor, interleukin-2, and gamma-interferon in serum after injection of OKT3 monoclonal antibody in kidney transplant recipients Transplantation 47 1989 606-608
-
(1989)
Transplantation
, vol.47
, pp. 606-608
-
-
Abramowicz, D.1
Schandene, L.2
Goldman, M.3
Crusiaux, A.4
Vereerstraeten, P.5
De Pauw, L.6
Wybran, J.7
Kinnaert, P.8
Dupont, E.9
Toussaint, C.10
-
10
-
-
0024588763
-
Effects of in vivo administration of anti-CD3 monoclonal antibody on T cell function in mice. II. In vivo activation of T cells
-
Hirsch R. Gress R.E. Pluznik D.H. Eckhaus M. Bluestone J.A. Effects of in vivo administration of anti-CD3 monoclonal antibody on T cell function in mice. II. In vivo activation of T cells J Immunol 142 1989 737-743
-
(1989)
J. Immunol.
, vol.142
, pp. 737-743
-
-
Hirsch, R.1
Gress, R.E.2
Pluznik, D.H.3
Eckhaus, M.4
Bluestone, J.A.5
-
11
-
-
0025342326
-
Cytokine-related syndrome following injection of anti-CD3 monoclonal antibody: Further evidence for transient in vivo T cell activation
-
Ferran C. Sheehan K. Dy M. Schreiber R. Merite S. Landais P. Noel L.H. Grau G. Bluestone J. Bach J.F. et al. Cytokine-related syndrome following injection of anti-CD3 monoclonal antibody: further evidence for transient in vivo T cell activation Eur J Immunol 20 1990 509-515
-
(1990)
Eur. J. Immunol.
, vol.20
, pp. 509-515
-
-
Ferran, C.1
Sheehan, K.2
Dy, M.3
Schreiber, R.4
Merite, S.5
Landais, P.6
Noel, L.H.7
Grau, G.8
Bluestone, J.9
Bach, J.F.10
-
12
-
-
0025361331
-
Hypothermia and hypoglycemia induced by anti-CD3 monoclonal antibody in mice: Role of tumor necrosis factor
-
Alegre M. Vandenabeele P. Flamand V. Moser M. Leo O. Abramowicz D. Urbain J. Fiers W. Goldman M. Hypothermia and hypoglycemia induced by anti-CD3 monoclonal antibody in mice: role of tumor necrosis factor Eur J Immunol 20 1990 707-710
-
(1990)
Eur. J. Immunol.
, vol.20
, pp. 707-710
-
-
Alegre, M.1
Vandenabeele, P.2
Flamand, V.3
Moser, M.4
Leo, O.5
Abramowicz, D.6
Urbain, J.7
Fiers, W.8
Goldman, M.9
-
13
-
-
0023481311
-
Induction of T cell proliferation with anti-CD3 switch-variant monoclonal antibodies: Effects of heavy chain isotype in monocyte-dependent systems
-
Van Lier R.A. Boot J.H. De Groot E.R. Aarden L.A. Induction of T cell proliferation with anti-CD3 switch-variant monoclonal antibodies: effects of heavy chain isotype in monocyte-dependent systems Eur J Immunol 17 1987 1599-1604
-
(1987)
Eur. J. Immunol.
, vol.17
, pp. 1599-1604
-
-
Van Lier, R.A.1
Boot, J.H.2
De Groot, E.R.3
Aarden, L.A.4
-
14
-
-
0025313268
-
Anti-CD3 F(ab′)2 fragments are immunosuppressive in vivo without evoking either the strong humoral response or morbidity associated with whole mAb
-
Hirsch R. Bluestone J.A. De Nenno L. Gress R.E. Anti-CD3 F(ab′)2 fragments are immunosuppressive in vivo without evoking either the strong humoral response or morbidity associated with whole mAb Transplantation 49 1990 1117-1123
-
(1990)
Transplantation
, vol.49
, pp. 1117-1123
-
-
Hirsch, R.1
Bluestone, J.A.2
De Nenno, L.3
Gress, R.E.4
-
16
-
-
0031569177
-
CD3 antibody-induced dominant self tolerance in overtly diabetic NOD mice
-
Chatenoud L. Primo J. Bach J.F. CD3 antibody-induced dominant self tolerance in overtly diabetic NOD mice J Immunol 158 1997 2947-2954
-
(1997)
J. Immunol.
, vol.158
, pp. 2947-2954
-
-
Chatenoud, L.1
Primo, J.2
Bach, J.F.3
-
17
-
-
0027958044
-
Anti-CD3 antibody induces long-term remission of overt autoimmunity in nonobese diabetic mice
-
Chatenoud L. Thervet E. Primo J. Bach J.F. Anti-CD3 antibody induces long-term remission of overt autoimmunity in nonobese diabetic mice Proc Natl Acad Sci USA 91 1994 123-127
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 123-127
-
-
Chatenoud, L.1
Thervet, E.2
Primo, J.3
Bach, J.F.4
-
18
-
-
0028058940
-
Induction of T helper cell hyporesponsiveness in an experimental model of autoimmunity by using nonmitogenic anti-CD3 monoclonal antibody
-
Hughes C. Wolos J.A. Giannini E.H. Hirsch R. Induction of T helper cell hyporesponsiveness in an experimental model of autoimmunity by using nonmitogenic anti-CD3 monoclonal antibody J Immunol 153 1994 3319-3325
-
(1994)
J. Immunol.
, vol.153
, pp. 3319-3325
-
-
Hughes, C.1
Wolos, J.A.2
Giannini, E.H.3
Hirsch, R.4
-
20
-
-
0028989604
-
Use of anti-CD3 epsilon F(ab′)2 fragments in vivo to modulate graft-versus-host disease without loss of graft-versus-leukemia reactivity after MHC-matched bone marrow transplantation
-
Johnson B.D. Mccabe C. Hanke C.A. Truitt R.L. Use of anti-CD3 epsilon F(ab′)2 fragments in vivo to modulate graft-versus-host disease without loss of graft-versus-leukemia reactivity after MHC-matched bone marrow transplantation J Immunol 154 1995 5542-5554
-
(1995)
J. Immunol.
, vol.154
, pp. 5542-5554
-
-
Johnson, B.D.1
Mccabe, C.2
Hanke, C.A.3
Truitt, R.L.4
-
21
-
-
0027458717
-
The generation of a humanized, non-mitogenic CD3 monoclonal antibody which retains in vitro immunosuppressive properties
-
Bolt S. Routledge E. Lloyd I. Chatenoud L. Pope H. Gorman S.D. Clark M. Waldmann H. The generation of a humanized, non-mitogenic CD3 monoclonal antibody which retains in vitro immunosuppressive properties Eur J Immunol 23 1993 403-411
-
(1993)
Eur. J. Immunol.
, vol.23
, pp. 403-411
-
-
Bolt, S.1
Routledge, E.2
Lloyd, I.3
Chatenoud, L.4
Pope, H.5
Gorman, S.D.6
Clark, M.7
Waldmann, H.8
-
22
-
-
0028178492
-
A non-activating 'humanized' anti-CD3 monoclonal antibody retains immunosuppressive properties in vivo
-
Alegre M.L. Peterson L.J. Xu D. Sattar H.A. Jeyarajah D.R. Kowalkowski K. Thistlethwaite J.R. Zivin R.A. Jolliffe L. Bluestone J.A. A non-activating 'humanized' anti-CD3 monoclonal antibody retains immunosuppressive properties in vivo Transplantation 57 1994 1537-1543
-
(1994)
Transplantation
, vol.57
, pp. 1537-1543
-
-
Alegre, M.L.1
Peterson, L.J.2
Xu, D.3
Sattar, H.A.4
Jeyarajah, D.R.5
Kowalkowski, K.6
Thistlethwaite, J.R.7
Zivin, R.A.8
Jolliffe, L.9
Bluestone, J.A.10
-
23
-
-
0032524957
-
Partial TCR signals delivered by FcR-nonbinding anti-CD3 monoclonal antibodies differentially regulate individual Th subsets
-
Smith J.A. Tang Q. Bluestone J.A. Partial TCR signals delivered by FcR-nonbinding anti-CD3 monoclonal antibodies differentially regulate individual Th subsets J Immunol 160 1998 4841-4849
-
(1998)
J. Immunol.
, vol.160
, pp. 4841-4849
-
-
Smith, J.A.1
Tang, Q.2
Bluestone, J.A.3
-
24
-
-
0030896612
-
Nonmitogenic anti-CD3 monoclonal antibodies deliver a partial T cell receptor signal and induce clonal anergy
-
Smith J.A. Tso J.Y. Clark M.R. Cole M.S. Bluestone J.A. Nonmitogenic anti-CD3 monoclonal antibodies deliver a partial T cell receptor signal and induce clonal anergy J Exp Med 185 1997 1413-1422
-
(1997)
J. Exp. Med.
, vol.185
, pp. 1413-1422
-
-
Smith, J.A.1
Tso, J.Y.2
Clark, M.R.3
Cole, M.S.4
Bluestone, J.A.5
-
25
-
-
0037313086
-
CD3-specific antibody-induced active tolerance: From bench to bedside
-
Chatenoud L. CD3-specific antibody-induced active tolerance: from bench to bedside Nat Rev Immunol 3 2003 123-132
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 123-132
-
-
Chatenoud, L.1
-
28
-
-
0026088887
-
Selective reduction and proliferation of the CD4+ and CD8+ T cell subsets with bispecific monoclonal antibodies: Evidence for inter-T cell-mediated cytolysis
-
Wong J.T. Colvin R.B. Selective reduction and proliferation of the CD4+ and CD8+ T cell subsets with bispecific monoclonal antibodies: evidence for inter-T cell-mediated cytolysis Clin Immunol Immunopathol 58 1991 236-250
-
(1991)
Clin. Immunol. Immunopathol.
, vol.58
, pp. 236-250
-
-
Wong, J.T.1
Colvin, R.B.2
-
29
-
-
0027315279
-
Induction of activation-driven death (apoptosis) in activated but not resting peripheral blood T cells
-
Wesselborg S. Janssen O. Kabelitz D. Induction of activation-driven death (apoptosis) in activated but not resting peripheral blood T cells J Immunol 150 1993 4338-4345
-
(1993)
J. Immunol.
, vol.150
, pp. 4338-4345
-
-
Wesselborg, S.1
Janssen, O.2
Kabelitz, D.3
-
30
-
-
0002865658
-
Antigenic modulation: A major mechanism of antibody action
-
Chatenoud L. Bach J.F. Antigenic modulation: a major mechanism of antibody action Immunol Today 5 1984 20-25
-
(1984)
Immunol. Today
, vol.5
, pp. 20-25
-
-
Chatenoud, L.1
Bach, J.F.2
-
32
-
-
0033608422
-
Induction of specific tolerance to allografts in rats by therapy with non-mitogenic, non-depleting anti-CD3 monoclonal antibody: Association with TH2 cytokines not anergy
-
Plain K.M. Chen J. Merten S. He X.Y. Hall B.M. Induction of specific tolerance to allografts in rats by therapy with non-mitogenic, non-depleting anti-CD3 monoclonal antibody: association with TH2 cytokines not anergy Transplantation 67 1999 605-613
-
(1999)
Transplantation
, vol.67
, pp. 605-613
-
-
Plain, K.M.1
Chen, J.2
Merten, S.3
He, X.Y.4
Hall, B.M.5
-
33
-
-
0141796312
-
TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes
-
Belghith M. Bluestone J.A. Barriot S. Megret J. Bach J.F. Chatenoud L. TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes Nat Med 9 2003 1202-1208
-
(2003)
Nat. Med.
, vol.9
, pp. 1202-1208
-
-
Belghith, M.1
Bluestone, J.A.2
Barriot, S.3
Megret, J.4
Bach, J.F.5
Chatenoud, L.6
-
34
-
-
0035187182
-
Suppressor T cells-they're back and critical for regulation of autoimmunity!
-
Chatenoud L. Salomon B. Bluestone J.A. Suppressor T cells-they're back and critical for regulation of autoimmunity! Immunol Rev 182 2001 149-163
-
(2001)
Immunol. Rev.
, vol.182
, pp. 149-163
-
-
Chatenoud, L.1
Salomon, B.2
Bluestone, J.A.3
-
35
-
-
0034716925
-
Regulatory T cells: Key controllers of immunologic self-tolerance
-
Sakaguchi S. Regulatory T cells: key controllers of immunologic self-tolerance Cell 101 2000 455-458
-
(2000)
Cell
, vol.101
, pp. 455-458
-
-
Sakaguchi, S.1
-
36
-
-
0033572786
-
Phase I study of an engineered aglycosylated humanized CD3 antibody in renal transplant rejection
-
Friend P.J. Hale G. Chatenoud L. Rebello P. Bradley J. Thiru S. Phillips J.M. Waldmann H. Phase I study of an engineered aglycosylated humanized CD3 antibody in renal transplant rejection Transplantation 68 1999 1632-1637
-
(1999)
Transplantation
, vol.68
, pp. 1632-1637
-
-
Friend, P.J.1
Hale, G.2
Chatenoud, L.3
Rebello, P.4
Bradley, J.5
Thiru, S.6
Phillips, J.M.7
Waldmann, H.8
-
37
-
-
0033568236
-
Phase I trial of a humanized, Fc receptor nonbinding OKT3 antibody, huOKT3gamma1(Ala-Ala) in the treatment of acute renal allograft rejection
-
Woodle E.S. Xu D. Zivin R.A. Auger J. Charette J. O'laughlin R. Peace D. Jollife L.K. Haverty T. Bluestone J.A. et al. Phase I trial of a humanized, Fc receptor nonbinding OKT3 antibody, huOKT3gamma1(Ala-Ala) in the treatment of acute renal allograft rejection Transplantation 68 1999 608-616
-
(1999)
Transplantation
, vol.68
, pp. 608-616
-
-
Woodle, E.S.1
Xu, D.2
Zivin, R.A.3
Auger, J.4
Charette, J.5
O'laughlin, R.6
Peace, D.7
Jollife, L.K.8
Haverty, T.9
Bluestone, J.A.10
-
38
-
-
0037198420
-
Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus
-
Herold K.C. Hagopian W. Auger J.A. Poumian Ruiz E. Taylor L. Donaldson D. Gitelman S.E. Harlan D.M. Xu D. Zivin R.A. et al. Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus N Engl J Med 346 2002 1692-1698
-
(2002)
N. Engl. J. Med.
, vol.346
, pp. 1692-1698
-
-
Herold, K.C.1
Hagopian, W.2
Auger, J.A.3
Poumian Ruiz, E.4
Taylor, L.5
Donaldson, D.6
Gitelman, S.E.7
Harlan, D.M.8
Xu, D.9
Zivin, R.A.10
-
39
-
-
0036733642
-
Modified anti-CD3 therapy in psoriatic arthritis: A phase I/II clinical trial
-
Utset T.O. Auger J.A. Peace D. Zivin R.A. Xu D. Jolliffe L. Alegre M.L. Bluestone J.A. Clark M.R. Modified anti-CD3 therapy in psoriatic arthritis: a phase I/II clinical trial J Rheumatol 29 2002 1907-1913
-
(2002)
J. Rheumatol.
, vol.29
, pp. 1907-1913
-
-
Utset, T.O.1
Auger, J.A.2
Peace, D.3
Zivin, R.A.4
Xu, D.5
Jolliffe, L.6
Alegre, M.L.7
Bluestone, J.A.8
Clark, M.R.9
-
40
-
-
10744219939
-
Transplantation of cultured islets from two-layer preserved pancreases in type 1 diabetes with anti-CD3 antibody
-
Hering B.J. Kandaswamy R. Harmon J.V. Ansite J.D. Clemmings S.M. Sakai T. Paraskevas S. Eckman P.M. Sageshima J. Nakano M. et al. Transplantation of cultured islets from two-layer preserved pancreases in type 1 diabetes with anti-CD3 antibody Am J Transplant 4 2004 390-401
-
(2004)
Am. J. Transplant
, vol.4
, pp. 390-401
-
-
Hering, B.J.1
Kandaswamy, R.2
Harmon, J.V.3
Ansite, J.D.4
Clemmings, S.M.5
Sakai, T.6
Paraskevas, S.7
Eckman, P.M.8
Sageshima, J.9
Nakano, M.10
|