Target-biased scoring approaches and expert systems in structure-based virtual screening

Current Opinion in Chemical Biology

Volumn 8, Issue 4, 2004, Pages 359-364

  Jansen, Johanna M ^a   Martin, Eric J ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

interaction pattern; IP; partial least squares; PLS; SIFt; structural interaction fingerprint; structure based virtual screening; SVS

Indexed keywords

PHOSPHOTRANSFERASE INHIBITOR;

BIOFILTER; DRUG SCREENING; DRUG STRUCTURE; DRUG TARGETING; HUMAN; MONTE CARLO METHOD; NONHUMAN; QUANTITATIVE ANALYSIS; REVIEW; SCORING SYSTEM;

ALGORITHMS; BINDING SITES; COMPUTER-AIDED DESIGN; DRUG DESIGN; EXPERT SYSTEMS; LIGANDS; PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 3342933156     PISSN: 13675931     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbpa.2004.06.002     Document Type: Review

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