A pilot trial of topiramate for the treatment of cocaine dependence

Drug and Alcohol Dependence

Volumn 75, Issue 3, 2004, Pages 233-240

  Kampman, Kyle M ^a,b   Pettinati, Helen ^a   Lynch, Kevin G ^a   Dackis, Charles ^a   Sparkman, Thorne ^a   Weigley, Catherine ^a   O'Brien, Charles P ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Clinical trial; Cocaine; GABA; Glutamate; Topiramate

Indexed keywords

BENZOYLECGONINE; COCAINE; PLACEBO; TOPIRAMATE;

ABSTINENCE; ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; COCAINE DEPENDENCE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG WITHDRAWAL; FEMALE; HUMAN; LABORATORY TEST; MALE; MATHEMATICAL MODEL; OUTCOMES RESEARCH; PILOT STUDY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SEDATION; SIDE EFFECT; SLURRED SPEECH; STATISTICAL SIGNIFICANCE; TITRIMETRY; URINE;

ADOLESCENT; ADULT; CHI-SQUARE DISTRIBUTION; COCAINE; COCAINE-RELATED DISORDERS; DOUBLE-BLIND METHOD; FEMALE; FRUCTOSE; HUMANS; MALE; MIDDLE AGED; PILOT PROJECTS;

EID: 3342889817     PISSN: 03768716     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.drugalcdep.2004.03.008     Document Type: Article

References (46)

1. Berger S.P., Hall S., Mickalian J.D., Reid M., Crawford C.A., Delucchi K., Carr K., Hall S. Haloperidol antagonism of cue-elicited cocaine craving. Lancet. 347:1996;504-508
2. Bowman E.M., Aigner T.G., Richmond B.J. Neural signals in the monkey ventral striatum related to motivation for juice and cocaine rewards. J. Neurophysiol. 75:1996;1061-1073
3. Carroll K., Rounsaville B.J., Gordon L.T., Nich C., Jatlow P., Gawin F. One-year follow up of psychotherapy and pharmacotherapy for cocaine dependence: delayed emergence of psychotherapy effects. Arch. Gen. Psychiatry. 51:1994;989-997
4. Childress, A., Ehrman, R., Damaris, J., Rohsenow, D., Robbins, S., O'Brien, C.P., 1993. Classically conditioned factors in drug dependence. In: Lowinson, J., Ruiz, P., Millman, R. (Eds.), Comprehensive Textbook of Substance Abuse. Williams and Wilkins, Baltimore, pp. 56-69.
5. Childress A.R., Mozley P.D., McElgin W., Fitzgerald J., Reivich M., O'Brien C.P. Limbic activation during cue-induced craving. Am. J. Psychiatry. 156:1999;11-18
6. Cornish J.L., Kalivas P.W. Glutamate transmission in the nucleus accumbens mediates relapse in cocaine addiction. J. Neurosci. 20:2000;1-5
7. de Lima M.S., de Oliveira Soares B.G., Reisser A.A.P., Farrell M. Pharmacological treatment of cocaine dependence: a systematic review. Addiction. 97:2000;931-949
8. Dewey S., Morgan A., Ashby C., Horan B., Kushner S., Logan J., Volkow N., Fowler J., Gardner E., Brodie J. A novel strategy for the treatment of cocaine addiction. Synapse. 30:1998;119-129
9. Dewey S., Smith G., Logan J., Brodie J., Yu D., Ferrieri R., King P., MacGregor R., Martin T., Wolf A.P. GABAergic inhibition of endogenous dopamine release measured in vivo with 11c-raclopride and positron emission tomography. J. Neurosci. 12:1992;3773-3780
10. Dewey S.L., Chaurasia C.S., Chen C., Volkow N.D., Clarkson F.A., Porter S., Straughter-Moore R.M., Alexoff D.L., Tedeschi D., Russo N.B., Fowler J.S., Brodie J.D. GABAergic attenuation of cocaine-induced dopamine release and locomoter activity. Synapse. 25:1997;393-398
11. Diggle, P.J., Liang, K.Y., Zeger, S.L., 1994. Analysis of Longitudinal Data. Oxford University Press, New York.
12. Dworkin, S.I., Smith, J.E., 1988. Neurobehavioral pharmacology of cocaine. In: Clouet, D., Ashgar, K., Brown, R. (Eds.), Mechanisms of Cocaine Abuse and Toxicity. National Institute on Drug Abuse Research Monograph #88. US Government Printing Office, Washington, DC, pp. 185-198.
13. Gerasimov M.R., Ashby C.R., Gardner E.L., Mills M.J., Brodie J.D., Dewey S.L. Gamma-vinyl-GABA inhibits methamphetamine, heroin, or ethanol-induced increases in nucleus accumbens dopamine. Synapse. 34:1999;11-19
14. Goeders N.E., Dworkin S.I., Smith J.E. Neuropharmacological assessment of cocaine self-administration into the medial prefrontal cortex. Pharmacol. Biochem. Behav. 24:1986;1429-1440
15. Guy, W. (Ed.), 1976. Assessment Manual for Psychopharmacology: Publication ADM 76-338. US Department of Health Education and Welfare, Washington, DC.
16. Johnson B.A., Ait-Daoud N., Bowden C.L., DiClemente C.C., Roache J.D., Lawson K., Javors M.A., Ma J.Z. Oral topiramate for the treatment of alcohol dependence: a randomized controlled trial. Lancet. 361:2003;1677-1685
17. Kadden, R., Carroll, K., Donovan, D., Cooney, N., Monti, P., Abrams, D., Litt, M., Hester, R., 1995. Cognitive-Behavioral Coping Skills Therapy Manual: A Clinical Research Guide for Therapists Treating Individuals With Alcohol abuse and Dependence. National Institutes of Health, Rockville, MD.
18. Kampman K.M., Alterman A.I., Volpicelli J.R., Maany I., Muller E.S., Luce D.D., Mulholland E.M., Jawad A., Parikh G., Mulvaney F.D., Weinieb R.M., O'Brien C.P. Cocaine withdrawal symptoms and initial urine toxicology results predict treatment attrition in outpatient cocaine dependence treatment. Psychol. Addict. Behav. 15:2001a;52-59
19. Kampman K.M., Volpicelli J.R., Alterman A.I., Cornish J.W., O'Brien C.P. Amantadine in the treatment of cocaine dependent patients with severe cocaine withdrawal symptoms. Am. J. Psychiatry. 157:2000;2052-2054
20. Kampman K.M., Volpicelli J.R., McGinnis D.E., Alterman A.I., Weinrieb R.M., D'Angelo L., Epperson L. Reliability and validity of the Cocaine Selective Severity Assessment. Addict. Behav. 23:1998;449-461
21. Kampman K.M., Volpicelli J.R., Mulvaney F.D., Alterman A.I., Cornish J., Gariti P., Cnaan A., Poole S., Muller E., Acosta T., Luce D., O'Brien C.P. Effectiveness of propranolol for cocaine dependence may depend on cocaine withdrawal symptom severity. Drug Alcohol Depend. 63:2001b;69-78
22. Kampman K.M., Volpicelli J.R., Mulvaney F.D., Rukstalis M., Alterman A.I., Pettinati H., Weinieb R.M., O'Brien C.P. Cocaine withdrawal severity and urine toxicology results from treatment entry predict outcome in medication trials for cocaine dependence. Addict. Behav. 27:2002;251-260
23. Koob, G., Vaccarino, F., Amalric, M., Bloom, F., 1987. Positive reinforcement properties of drugs: search for neural substrates. In: Engel, J., Oreland, L. (Eds.), Brain Reward Systems and Abuse. Raven Press, New York, pp. 35-50.
24. Koob G.F. Neural mechanisms of drug reinforcement. Ann. N.Y. Acad. Sci. 654:1992;171-191
25. Kosten T., Gawin F.H., Kosten T.A., Morgan C., Rounsaville B.J., Schottenfeld R., Kleber H.D. Six-month follow-up of short-term pharmacotherapy for cocaine dependence. Am. J. Addict. 1:1992;40-49
26. Kushner S.A., Dewey S.L., Kornetsky C. The irreversible γ-aminobutyric acid (GABA) transaminase inhibitor γ-vinyl-GABA blocks cocaine self-administration in rats. J. Pharmacol. Exp. Ther. 290:1999;797-802
27. Kuzniecky R., Hetherington H., Ho S., Pan J., Martin R., Gilliam F., Hugg J., Faught E. Topiramate increases cerebral GABA in healthy humans. Neurology. 51:1998;627-629
28. Littell, R.C., Milliken, G.A., Stroup, W.W., Wolfinger, R.D., 1996. SAS System for Mixed Models. SAS Institute Inc, Cary, NC.
29. Littell R.C., Pendergast J., Natarajan R. Modeling covariance structure in the analysis of repeated measures data. Stat. Med. 19:2000;1793-1819
30. McFarland K., Kalivas P.W. The circuitry mediating cocaine-induced reinstatement of drug-seeking behavior. J. Neurosci. 21:2001;8655-8663
31. McFarland K., Lapish C.C., Kalivas P.W. Prefrontal glutamate release into the core of the nucleus accumbens mediates cocaine-induced reinstatement of drug seeking behavior. J. Neurosci. 23:2003;3531-3537
32. McLellan A.T., Kushner H., Metzger D., Peters R., Smith I., Grissom G., Pettinati H., Argeriou M. The fifth edition of the addiction severity index. J. Subst. Abuse Treat. 9:1992;199-213
33. Mulvaney F.D., Alterman A.I., Boardman C.R., Kampman K. Cocaine abstinence symptomatology and treatment attrition. J. Subst. Abuse Treat. 16:1999;129-135
34. Petroff O.A., Hyder F., Mattson R.H., Rothman D.L. Topiramate increases brain GABA, homocarnasine, and pyrrolidinone in patients with epilepsy. Neurology. 52:1999;473-478
35. Privetera M.D. Topiramate: a new antiepileptic drug. Ann. Pharmacother. 31:1997;1164-1173
36. Roberts D.C.S., Koob G.F., Klonoff P., Figiber H.C. Extinction and recovery of cocaine self-administration following 6-hydroxydopamine lesions of the nucleus accumbens. Pharmacol. Biochem. Behav. 12:1980;781-787
37. Roberts D.C., Andrews M.M., Vickers G.J. Baclofen attenuates the reinforcing effects of cocaine in rats. Neuropsychopharmacology. 15:1996;417-423
38. Rubio G., Ponce G., Jimenez-Arriero M.A., Palomo T., Ferre F. Effectiveness of topiramate in control of alcohol craving. Eur. Neuropsychopharmacol. 12:2002;S63
39. Schultz W. Predictive reward signals of dopamine neurons. J. Neurophysiol. 80:1998;1-27
40. Severt L., Coulter D.S., Sombati S. Topiramate selectively blocks kainate currents in cultured hippocampal neurons. Epilepsia. 36:1995;38
41. Sharples K., Breslow N. Regression analysis of correlated binary data: some small sample results for the estimating equation approach. J. Stat. Comput. Simul. 42:1992;1-20
42. Somoza, E., Dyrenforth, S., Goldsmith, J., Mezinskis, J., Cohen, M., 1995. In search of a universal drug craving scale. Paper Presented at the Annual Meeting of the American Psychiatric Association, Miami, FL.
43. Weiss F., Maldanado-Vlaar C.S., Parsons L.H., Kerr T.M., Smith D.L., Ben-Shahar O. Control of cocaine-seeking behavior by drug-associated stimuli in rats: effects on recovery of extinguished operant responding and extracellular dopamine levels in amygdala and nucleus accumbens. Proc. Natl. Acad. Sci. U.S.A. 97:2000;4321-4326
44. Westerink B.H.C., Enrico P., Feiman J., De Vries J.B. The pharmacology of mesocortical dopamine neurons: a dual probe microdialysis study of the ventral tegmental area and prefrontal cortex of the rat brain. J. Pharmacol. Exp. Ther. 285:1998;143-154
45. White H.S., Brown S.D., Woodhead J.H., Skeen G.A., Wolof H.H. Topiramate enhances GABA-mediated chloride flux and GABA-evoked chloride currents in murine brain neurons and increases seizure threshold. Epilepsy Res. 28:1997;167-179
46. Zullino D.F., Cottier A.C., Besson J. Topiramate in opiate withdrawal. Prog. Neuropsychopharmacol. Biol. Psychiatry. 26:2002;1221-1223