메뉴 건너뛰기




Volumn 31, Issue 10, 1997, Pages 1164-1173

Topiramate: A new antiepileptic drug

Author keywords

Epilepsy; Topiramate

Indexed keywords

TOPIRAMATE;

EID: 0030931470     PISSN: 10600280     EISSN: None     Source Type: Journal    
DOI: 10.1177/106002809703101010     Document Type: Review
Times cited : (99)

References (66)
  • 1
    • 0002544304 scopus 로고
    • General principles: Experimental selection, quantification and evaluation of anticonvulsants
    • Levy R, Mattson RM, Meldrum B, Penry JK, Dreifuss FE, eds. New York: Raven Press
    • Swinyard EA, Woodhead JH, White HS, Franklin MR. General principles: experimental selection, quantification and evaluation of anticonvulsants. In: Levy R, Mattson RM, Meldrum B, Penry JK, Dreifuss FE, eds. Antiepileptic drugs. 3rd ed. New York: Raven Press, 1989:85-102.
    • (1989) Antiepileptic Drugs. 3rd Ed. , pp. 85-102
    • Swinyard, E.A.1    Woodhead, J.H.2    White, H.S.3    Franklin, M.R.4
  • 2
    • 0002295577 scopus 로고
    • Investigation of the mechanism of topiramate's anticonvulsant activity
    • Shank RP, Vaught JL, Raffa RB, Maryanoff BE. Investigation of the mechanism of topiramate's anticonvulsant activity. Epilepsia 1991;32:7-8.
    • (1991) Epilepsia , vol.32 , pp. 7-8
    • Shank, R.P.1    Vaught, J.L.2    Raffa, R.B.3    Maryanoff, B.E.4
  • 4
    • 1842422933 scopus 로고    scopus 로고
    • Effect of topiramate (TPM) on pentylenetetrazol (PTZ) seizure threshold
    • White HS, Woodhead JH, Wolf HH. Effect of topiramate (TPM) on pentylenetetrazol (PTZ) seizure threshold (abstract). Epilepsia 1996;37 (suppl 5):26.
    • (1996) Epilepsia , vol.37 , Issue.5 SUPPL. , pp. 26
    • White, H.S.1    Woodhead, J.H.2    Wolf, H.H.3
  • 5
  • 6
    • 0029057901 scopus 로고
    • Antiepileptic drug mechanisms of action
    • Macdonald RL, Kelly KM. Antiepileptic drug mechanisms of action. Epilepsia 1995;36(suppl 2):S2-12.
    • (1995) Epilepsia , vol.36 , Issue.2 SUPPL.
    • Macdonald, R.L.1    Kelly, K.M.2
  • 7
    • 0000337336 scopus 로고
    • Selective effects of topiramate on sustained repetitive firing and spontaneous bursting in cultured hippocampal neurons
    • Coulter DA, Sombati S, DeLorenzo RJ. Selective effects of topiramate on sustained repetitive firing and spontaneous bursting in cultured hippocampal neurons (abstract). Epilepsia 1993;34(suppl 2):123.
    • (1993) Epilepsia , vol.34 , Issue.2 SUPPL. , pp. 123
    • Coulter, D.A.1    Sombati, S.2    DeLorenzo, R.J.3
  • 8
    • 0002836369 scopus 로고
    • 2+-induced seizure discharged in cultured hippocampal neurons
    • 2+-induced seizure discharged in cultured hippocampal neurons (abstract). Epilepsia 1995;36(suppl 4):38.
    • (1995) Epilepsia , vol.36 , Issue.4 SUPPL. , pp. 38
    • Sombati, S.1    Coulter, D.A.2    DeLorenzo, R.J.3
  • 9
    • 0000337340 scopus 로고
    • The novel anticonvulsant topiramate enhances GABA-mediated chloride flux
    • Brown SD, Wolf HH, Swinyard EA, Twyman RE, White HS. The novel anticonvulsant topiramate enhances GABA-mediated chloride flux (abstract). Epilepsia 1993;34(suppl 2):122.
    • (1993) Epilepsia , vol.34 , Issue.2 SUPPL. , pp. 122
    • Brown, S.D.1    Wolf, H.H.2    Swinyard, E.A.3    Twyman, R.E.4    White, H.S.5
  • 10
    • 0007092669 scopus 로고
    • The anticonvulsant topiramate potentiates GABA-evoked chloride currents in mouse cortical neurons
    • White HS, Brown SD, Wolf HH, Twyman RE. The anticonvulsant topiramate potentiates GABA-evoked chloride currents in mouse cortical neurons (abstract). Epilepsia 1994;35(suppl 8):67.
    • (1994) Epilepsia , vol.35 , Issue.8 SUPPL. , pp. 67
    • White, H.S.1    Brown, S.D.2    Wolf, H.H.3    Twyman, R.E.4
  • 11
    • 0002394897 scopus 로고
    • The anticonvulsant topiramate displays a unique ability to potentiate GABA-evoked chloride currents
    • White HS, Brown D, Skeen GA, Wolf HH, Twyman RE. The anticonvulsant topiramate displays a unique ability to potentiate GABA-evoked chloride currents (abstract). Epilepsia 1995:36(suppl 3):S39-40.
    • (1995) Epilepsia , vol.36 , Issue.3 SUPPL.
    • White, H.S.1    Brown, D.2    Skeen, G.A.3    Wolf, H.H.4    Twyman, R.E.5
  • 12
    • 0002500916 scopus 로고
    • The investigational anticonvulsant topiramate potentiates GABA-evoked currents in mouse cortical neurons
    • White HS, Brown SD, Skeen GA, Twyman RE. The investigational anticonvulsant topiramate potentiates GABA-evoked currents in mouse cortical neurons (abstract). Epilepsia 1995;36(suppl 4):34.
    • (1995) Epilepsia , vol.36 , Issue.4 SUPPL. , pp. 34
    • White, H.S.1    Brown, S.D.2    Skeen, G.A.3    Twyman, R.E.4
  • 13
    • 0011143924 scopus 로고
    • Topiramate modulates GABA receptor responses in Xenopus oocytes expressing several recombinant receptor subunit combinations
    • Gordey M, Delorey TM, Olsen RW. Topiramate modulates GABA receptor responses in Xenopus oocytes expressing several recombinant receptor subunit combinations (abstract). Epilepsia 1995;36(suppl 4):48.
    • (1995) Epilepsia , vol.36 , Issue.4 SUPPL. , pp. 48
    • Gordey, M.1    Delorey, T.M.2    Olsen, R.W.3
  • 14
    • 0002836373 scopus 로고
    • Topiramate effects on excitatory amino acid-mediated responses in cultured hippocampal neurons: Selective blockade of kainate currents
    • Coulter DA, Sombati S, DeLorenzo RJ. Topiramate effects on excitatory amino acid-mediated responses in cultured hippocampal neurons: selective blockade of kainate currents (abstract). Epilepsia 1995;36(suppl 3):S40.
    • (1995) Epilepsia , vol.36 , Issue.3 SUPPL.
    • Coulter, D.A.1    Sombati, S.2    DeLorenzo, R.J.3
  • 15
    • 0011885285 scopus 로고
    • The pharmacological profile of topiramate: A structurally novel, clinically effective anticonvulsant
    • Vaught JL, Maryanoff BE, Shank RP. The pharmacological profile of topiramate: a structurally novel, clinically effective anticonvulsant (abstract). Epilepsia 1991;32(suppl 3):19.
    • (1991) Epilepsia , vol.32 , Issue.3 SUPPL. , pp. 19
    • Vaught, J.L.1    Maryanoff, B.E.2    Shank, R.P.3
  • 16
    • 0001847556 scopus 로고
    • Potential antiepileptic drugs: Topiramate
    • Levy RH, Mattson RM, Meldrum BS, eds. New York: Raven Press
    • Ben-Menachem E. Potential antiepileptic drugs: topiramate. In: Levy RH, Mattson RM, Meldrum BS, eds. Antiepileptic drugs. 4th ed. New York: Raven Press, 1995:1063-70.
    • (1995) Antiepileptic Drugs. 4th Ed. , pp. 1063-1070
    • Ben-Menachem, E.1
  • 17
    • 0028864135 scopus 로고
    • Important pharmacokinetic properties of antiepileptic drugs
    • Bourgeois BFD. Important pharmacokinetic properties of antiepileptic drugs. Epilepsia 1995;36(suppl 5):S1-7.
    • (1995) Epilepsia , vol.36 , Issue.5 SUPPL.
    • Bourgeois, B.F.D.1
  • 19
    • 80051499508 scopus 로고    scopus 로고
    • RW Johnson Pharmaceutical Research Institute, Raritan, NJ
    • Data on file. RW Johnson Pharmaceutical Research Institute, Raritan, NJ.
    • Data on File
  • 20
    • 0002275260 scopus 로고
    • The steady-state (SS) pharmacokinetics (PK) of phenytoin (Dilantin) and topiramate (Topamax) in epileptic patients on monotherapy and during combination therapy
    • Gisclon LG, Curtin CR, Kramer LD. The steady-state (SS) pharmacokinetics (PK) of phenytoin (Dilantin) and topiramate (Topamax) in epileptic patients on monotherapy and during combination therapy (abstract). Epilepsia 1994;35(suppl 8):54.
    • (1994) Epilepsia , vol.35 , Issue.8 SUPPL. , pp. 54
    • Gisclon, L.G.1    Curtin, C.R.2    Kramer, L.D.3
  • 21
    • 0002275260 scopus 로고
    • Steady-state pharmacokinetics of Tegretol (carbamazepine) and Topamax (topiramate) in patients with epilepsy on monotherapy, and during combination therapy
    • Doose DR, Walker SA, Sachdeo R, Kramer LD, Nayak RK. Steady-state pharmacokinetics of Tegretol (carbamazepine) and Topamax (topiramate) in patients with epilepsy on monotherapy, and during combination therapy (abstract). Epilepsia 1994;35(suppl 8):54.
    • (1994) Epilepsia , vol.35 , Issue.8 SUPPL. , pp. 54
    • Doose, D.R.1    Walker, S.A.2    Sachdeo, R.3    Kramer, L.D.4    Nayak, R.K.5
  • 22
    • 0000569058 scopus 로고
    • The pharmacokinetics (PK) of topiramate (T) in subjects with renal impairment (RI) as compared to matched subjects with normal renal function (NRF) (abstract)
    • Gisclon LG, Riffits JM, Sica DA, Gehr T, Ruddley J. The pharmacokinetics (PK) of topiramate (T) in subjects with renal impairment (RI) as compared to matched subjects with normal renal function (NRF) (abstract). Pharm Res 1993;10(suppl 10):S397.
    • (1993) Pharm Res , vol.10 , Issue.10 SUPPL.
    • Gisclon, L.G.1    Riffits, J.M.2    Sica, D.A.3    Gehr, T.4    Ruddley, J.5
  • 24
    • 0029922566 scopus 로고    scopus 로고
    • Topiramate placebo-controlled dose-ranging trial in refractory epilepsy using 200-, 400- and 600-mg daily dosages
    • Faught E, Wilder BJ, Ramsay RE, Reife RA, Kramer LD, Pledger GW, et al. Topiramate placebo-controlled dose-ranging trial in refractory epilepsy using 200-, 400-and 600-mg daily dosages. Neurology 1996; 46:1684-90.
    • (1996) Neurology , vol.46 , pp. 1684-1690
    • Faught, E.1    Wilder, B.J.2    Ramsay, R.E.3    Reife, R.A.4    Kramer, L.D.5    Pledger, G.W.6
  • 25
    • 0029884747 scopus 로고    scopus 로고
    • Topiramate placebo-controlled dose-ranging trial in refractory partial epilepsy using 600-, 800- and 1000-mg daily dosages
    • Privitera M, Fincham R, Penry J, Reife R, Kramer L, Pledger G, et al. Topiramate placebo-controlled dose-ranging trial in refractory partial epilepsy using 600-, 800-and 1000-mg daily dosages. Neurology 1996; 46:1678-83.
    • (1996) Neurology , vol.46 , pp. 1678-1683
    • Privitera, M.1    Fincham, R.2    Penry, J.3    Reife, R.4    Kramer, L.5    Pledger, G.6
  • 26
    • 0003194480 scopus 로고
    • Double-blind, placebo-controlled trial of 400 mg/day topiramate as add-on therapy in patients with refractory partial epilepsy
    • Martinez-Lage J, Ben-Menachem E, Shorvon SD, Weber M. Double-blind, placebo-controlled trial of 400 mg/day topiramate as add-on therapy in patients with refractory partial epilepsy (abstract). Epilepsia 1995; 36(suppl 3):S149-50.
    • (1995) Epilepsia , vol.36 , Issue.3 SUPPL.
    • Martinez-Lage, J.1    Ben-Menachem, E.2    Shorvon, S.D.3    Weber, M.4
  • 27
    • 9444251680 scopus 로고    scopus 로고
    • Double-blind, placebo-controlled trial of topiramate (600 mg daily) for the treatment of refractory partial epilepsy
    • Tassinari CA, Michelucci R, Chauvel P, Chodkiewicz J, Shorvon S, Henriksen O, et al. Double-blind, placebo-controlled trial of topiramate (600 mg daily) for the treatment of refractory partial epilepsy. Epilepsia 1996;37:763-8.
    • (1996) Epilepsia , vol.37 , pp. 763-768
    • Tassinari, C.A.1    Michelucci, R.2    Chauvel, P.3    Chodkiewicz, J.4    Shorvon, S.5    Henriksen, O.6
  • 28
    • 0043181917 scopus 로고    scopus 로고
    • Double-blind, placebo-controlled trial of topiramate as add-on therapy in patients with refractory partial seizures
    • Ben-Menachem E, Henriksen O, Dam M, Mikkelsen M, Schmidt D, Reid S, et al. Double-blind, placebo-controlled trial of topiramate as add-on therapy in patients with refractory partial seizures. Epilepsia 1996;37: 539-43.
    • (1996) Epilepsia , vol.37 , pp. 539-543
    • Ben-Menachem, E.1    Henriksen, O.2    Dam, M.3    Mikkelsen, M.4    Schmidt, D.5    Reid, S.6
  • 29
    • 84944661914 scopus 로고
    • Rank transformation as a bridge between parametric and nonparametric statistics
    • Conover WJ, Iman RL. Rank transformation as a bridge between parametric and nonparametric statistics. Am Statistician 1981;35:124-33.
    • (1981) Am Statistician , vol.35 , pp. 124-133
    • Conover, W.J.1    Iman, R.L.2
  • 32
    • 0001285344 scopus 로고
    • Overview of topiramate efficacy from adjunctive therapy trials
    • Pledger G, Reife RA, Lim P, Karim P. Overview of topiramate efficacy from adjunctive therapy trials (abstract). Epilepsia 1995;36(suppl 3): S150.
    • (1995) Epilepsia , vol.36 , Issue.3 SUPPL.
    • Pledger, G.1    Reife, R.A.2    Lim, P.3    Karim, P.4
  • 33
    • 0028568192 scopus 로고
    • Evaluation of antiepileptic drug efficacy: A review of clinical trial design
    • Pledger GW, Schmidt D. Evaluation of antiepileptic drug efficacy: a review of clinical trial design. Drugs 1994;48:498-509.
    • (1994) Drugs , vol.48 , pp. 498-509
    • Pledger, G.W.1    Schmidt, D.2
  • 35
    • 0001402860 scopus 로고
    • An open-label multicenter study of topiramate in patients with the Lennox-Gastaut syndrome
    • French JA, Bourgeois BFD, Dreifuss FE, Glauser TA, Ritter FJ, Reife RA, et al. An open-label multicenter study of topiramate in patients with the Lennox-Gastaut syndrome (abstract). Neurology 1995;45(suppl 4):A250.
    • (1995) Neurology , vol.45 , Issue.4 SUPPL.
    • French, J.A.1    Bourgeois, B.F.D.2    Dreifuss, F.E.3    Glauser, T.A.4    Ritter, F.J.5    Reife, R.A.6
  • 36
    • 0002986435 scopus 로고
    • Topiramate in childhood epilepsy: Titration, adverse events, and efficacy in multiple seizure types
    • Espe-Lillo J, Ritter FJ, Frost MD, Spiegel RH, Reife RA. Topiramate in childhood epilepsy: titration, adverse events, and efficacy in multiple seizure types (abstract). Epilepsia 1995;36(suppl 4):56.
    • (1995) Epilepsia , vol.36 , Issue.4 SUPPL. , pp. 56
    • Espe-Lillo, J.1    Ritter, F.J.2    Frost, M.D.3    Spiegel, R.H.4    Reife, R.A.5
  • 37
    • 0000145915 scopus 로고    scopus 로고
    • Topiramate (Topamax) as add-on therapy for patients with primary generalized epilepsy
    • Biton V, Reife R, Kamin M, Bobrosky K. Topiramate (Topamax) as add-on therapy for patients with primary generalized epilepsy (abstract). Neurology 1996;43:A176.
    • (1996) Neurology , vol.43
    • Biton, V.1    Reife, R.2    Kamin, M.3    Bobrosky, K.4
  • 38
    • 0001196978 scopus 로고
    • Long-term efficacy and safety of topiramate
    • Privitera M. Long-term efficacy and safety of topiramate (abstract). Epilepsia 1995;36(suppl 3):S152.
    • (1995) Epilepsia , vol.36 , Issue.3 SUPPL.
    • Privitera, M.1
  • 39
    • 0011084251 scopus 로고
    • Topiramate can be a successful monotherapy drug
    • Rosenfeld WE, Sachdeo RC. Topiramate can be a successful monotherapy drug (abstract). Epilepsia 1995;36(suppl 4):56.
    • (1995) Epilepsia , vol.36 , Issue.4 SUPPL. , pp. 56
    • Rosenfeld, W.E.1    Sachdeo, R.C.2
  • 40
    • 0001196981 scopus 로고
    • Long-term follow-up of patients treated with topiramate for partial seizures
    • Ben-Menachem E. Long-term follow-up of patients treated with topiramate for partial seizures (abstract). Epilepsia 1995;36(suppl 3):S152.
    • (1995) Epilepsia , vol.36 , Issue.3 SUPPL.
    • Ben-Menachem, E.1
  • 41
    • 0011077704 scopus 로고
    • Topiramate as adjunctive therapy in patients with refractory epilepsy: A report of a long-term, open-label study
    • Cowell PG, Coles HJ, Crawford PM. Topiramate as adjunctive therapy in patients with refractory epilepsy: a report of a long-term, open-label study (abstract). Epilepsia 1995;36(suppl 3):S152.
    • (1995) Epilepsia , vol.36 , Issue.3 SUPPL.
    • Cowell, P.G.1    Coles, H.J.2    Crawford, P.M.3
  • 43
    • 0011107199 scopus 로고
    • Topiramate as long-term treatment in refractory partial epilepsy
    • Mikkelsen M, Ostergaard L, Dam M. Topiramate as long-term treatment in refractory partial epilepsy (abstract). Epilepsia 1993;35(suppl 2):123.
    • (1993) Epilepsia , vol.35 , Issue.2 SUPPL. , pp. 123
    • Mikkelsen, M.1    Ostergaard, L.2    Dam, M.3
  • 44
    • 15144357096 scopus 로고
    • Topiramate in the treatment of refractory partial epilepsy: A double-blind study with long-term follow-up
    • Michelucci R, Passarelli D, Tassinari CA. Topiramate in the treatment of refractory partial epilepsy: a double-blind study with long-term follow-up (abstract). Epilepsia 1995;36(suppl 3):S150.
    • (1995) Epilepsia , vol.36 , Issue.3 SUPPL.
    • Michelucci, R.1    Passarelli, D.2    Tassinari, C.A.3
  • 46
    • 0011083923 scopus 로고
    • Long-term therapy with topiramate in partial seizures
    • Fincham RW, Schottelius D. Long-term therapy with topiramate in partial seizures (abstract). Epilepsia 1995;36(suppl 4):56.
    • (1995) Epilepsia , vol.36 , Issue.4 SUPPL. , pp. 56
    • Fincham, R.W.1    Schottelius, D.2
  • 47
    • 15144341122 scopus 로고    scopus 로고
    • Raritan, NJ: Ortho McNeil Pharmaceutical, December
    • Package insert. Topamax (topiramate). Raritan, NJ: Ortho McNeil Pharmaceutical, December 1996.
    • (1996) Package Insert. Topamax (Topiramate)
  • 49
    • 0002932225 scopus 로고
    • Topiramate: Side effect profile in double-blind studies
    • Reife RA, Lim P, Pledger G. Topiramate: side effect profile in double-blind studies (abstract). Epilepsia 1995;36(suppl 4):34.
    • (1995) Epilepsia , vol.36 , Issue.4 SUPPL. , pp. 34
    • Reife, R.A.1    Lim, P.2    Pledger, G.3
  • 50
    • 0000268248 scopus 로고
    • Nephrolithiasis during treatment with topiramate
    • Wasserstein AG, Rak I, Reife RA. Nephrolithiasis during treatment with topiramate (abstract). Epilepsia 1995;36(suppl 3):S153.
    • (1995) Epilepsia , vol.36 , Issue.3 SUPPL.
    • Wasserstein, A.G.1    Rak, I.2    Reife, R.A.3
  • 51
    • 0013568160 scopus 로고
    • Steady-state pharmacokinetics of topiramate and valproic acid in patients with epilepsy on monotherapy and during combination therapy
    • Liao S, Rosenfeld WE, Palmer M, Schaefer P, Pace K, Nayak RK. Steady-state pharmacokinetics of topiramate and valproic acid in patients with epilepsy on monotherapy and during combination therapy (abstract). Epilepsia 1994;35(suppl 8):117.
    • (1994) Epilepsia , vol.35 , Issue.8 SUPPL. , pp. 117
    • Liao, S.1    Rosenfeld, W.E.2    Palmer, M.3    Schaefer, P.4    Pace, K.5    Nayak, R.K.6
  • 52
    • 0000844483 scopus 로고
    • Evaluation of phenobarbital and primidone/phenobarbital (primidone's active metabolite) plasma concentrations during administration of add-on topiramate therapy in five multicenter, double-blind, placebo-controlled trials in outpatients with partial seizures
    • Doose DR, Walker SA, Pledger G, Lim P, Reife RA. Evaluation of phenobarbital and primidone/phenobarbital (primidone's active metabolite) plasma concentrations during administration of add-on topiramate therapy in five multicenter, double-blind, placebo-controlled trials in outpatients with partial seizures (abstract). Epilepsia 1995;36(suppl 3):S158.
    • (1995) Epilepsia , vol.36 , Issue.3 SUPPL.
    • Doose, D.R.1    Walker, S.A.2    Pledger, G.3    Lim, P.4    Reife, R.A.5
  • 53
    • 0030910546 scopus 로고    scopus 로고
    • Effect of topiramate on the pharmacokinetics of an oral contraceptive containing norethindrone and ethinyl estradiol in patients with epilepsy
    • Rosenfeld WE, Doose DR, Walker SA, Nayak RK. Effect of topiramate on the pharmacokinetics of an oral contraceptive containing norethindrone and ethinyl estradiol in patients with epilepsy. Epilepsia 1997;38: 317-23.
    • (1997) Epilepsia , vol.38 , pp. 317-323
    • Rosenfeld, W.E.1    Doose, D.R.2    Walker, S.A.3    Nayak, R.K.4
  • 54
    • 0000580509 scopus 로고
    • Digoxin and topiramate drug interaction study in male volunteers
    • Liao S, Palmer M. Digoxin and topiramate drug interaction study in male volunteers (abstract). Pharm Res 1993;10(suppl):S405.
    • (1993) Pharm Res , vol.10 , Issue.SUPPL.
    • Liao, S.1    Palmer, M.2
  • 55
    • 0003059953 scopus 로고
    • Explanation and prediction of drug interactions with topiramate using a CYP450 inhibition spectrum
    • Levy RH, Bishop F, Streeter AJ, Trager WF, Kunze KL, Thummel KT, et al. Explanation and prediction of drug interactions with topiramate using a CYP450 inhibition spectrum (abstract). Epilepsia 1995;36(suppl 4):47.
    • (1995) Epilepsia , vol.36 , Issue.4 SUPPL. , pp. 47
    • Levy, R.H.1    Bishop, F.2    Streeter, A.J.3    Trager, W.F.4    Kunze, K.L.5    Thummel, K.T.6
  • 56
    • 0000844483 scopus 로고
    • Steady-state pharmacokinetics of topiramate as adjunctive therapy in pediatric subjects with epilepsy
    • Rosenfeld WE, Doose DR, Walker SA, Schaefer P, Reife RA. Steady-state pharmacokinetics of topiramate as adjunctive therapy in pediatric subjects with epilepsy (abstract). Epilepsia 1995;36(suppl 3):S158.
    • (1995) Epilepsia , vol.36 , Issue.3 SUPPL.
    • Rosenfeld, W.E.1    Doose, D.R.2    Walker, S.A.3    Schaefer, P.4    Reife, R.A.5
  • 57
    • 0002686581 scopus 로고
    • Topiramate well tolerated by pediatric patients
    • Thanedar S, Rosenfeld WE. Topiramate well tolerated by pediatric patients (abstract). Epilepsia 1995;36(suppl 4):34.
    • (1995) Epilepsia , vol.36 , Issue.4 SUPPL. , pp. 34
    • Thanedar, S.1    Rosenfeld, W.E.2
  • 58
    • 0026794763 scopus 로고
    • A comparison of valproate with carbamazepine for the treatment of complex partial seizures and secondarily generalized tonic-clonic seizures in adults
    • Mattson RH, Cramer JA, Collins JF, and the Department of Veterans Affairs Epilepsy Cooperative Study No. 264 Group. A comparison of valproate with carbamazepine for the treatment of complex partial seizures and secondarily generalized tonic-clonic seizures in adults. N Engl J Med 1992;327:765-71.
    • (1992) N Engl J Med , vol.327 , pp. 765-771
    • Mattson, R.H.1    Cramer, J.A.2    Collins, J.F.3
  • 59
    • 0028956555 scopus 로고
    • Phenobarbitone, phenytoin, carbamazepine, or sodium valproate for newly diagnosed adult epilepsy: A randomised comparative monotherapy trial
    • Heller AJ, Chesterman P, Elwes RDC, Crawford P, Chadwick D, Johnson AL, et al. Phenobarbitone, phenytoin, carbamazepine, or sodium valproate for newly diagnosed adult epilepsy: a randomised comparative monotherapy trial. J Neurol Neurosurg Psychiatry 1995;58:44-50.
    • (1995) J Neurol Neurosurg Psychiatry , vol.58 , pp. 44-50
    • Heller, A.J.1    Chesterman, P.2    Elwes, R.D.C.3    Crawford, P.4    Chadwick, D.5    Johnson, A.L.6
  • 60
    • 0028041242 scopus 로고
    • Gabapentin (Neurontin) as add-on therapy in patients with partial seizures: A double-blind, placebo-controlled study
    • Anhut H, Ashman P, Feuerstein TJ, Sauermann W, Saunders M, Schmidt B, et al. Gabapentin (Neurontin) as add-on therapy in patients with partial seizures: a double-blind, placebo-controlled study. Epilepsia 1994;35:795-801.
    • (1994) Epilepsia , vol.35 , pp. 795-801
    • Anhut, H.1    Ashman, P.2    Feuerstein, T.J.3    Sauermann, W.4    Saunders, M.5    Schmidt, B.6
  • 61
    • 0027374164 scopus 로고
    • Gabapentin as add-on therapy in refractory partial epilepsy: A double-blind, placebo-controlled, parallel-group study
    • US Gabapentin Study Group No. 5. Gabapentin as add-on therapy in refractory partial epilepsy: a double-blind, placebo-controlled, parallel-group study. Neurology 1993;43:2292-8.
    • (1993) Neurology , vol.43 , pp. 2292-2298
  • 62
    • 0027491284 scopus 로고
    • Placebo-controlled study of the efficacy and safety of lamotrigine in patients with partial seizures
    • Matsuo F, Bergen D, Faught E, Messenheimer JA, Dren AT, Rudd GD, et al. Placebo-controlled study of the efficacy and safety of lamotrigine in patients with partial seizures. Neurology 1993;43:2284-91.
    • (1993) Neurology , vol.43 , pp. 2284-2291
    • Matsuo, F.1    Bergen, D.2    Faught, E.3    Messenheimer, J.A.4    Dren, A.T.5    Rudd, G.D.6
  • 63
    • 0000083872 scopus 로고
    • Comparison of lamotrigine and phenytoin monotherapy in newly diagnosed epilepsy
    • Steiner TJ, Yuen AWC. Comparison of lamotrigine and phenytoin monotherapy in newly diagnosed epilepsy (abstract). Epilepsia 1994;35 (suppl 8):31.
    • (1994) Epilepsia , vol.35 , Issue.8 SUPPL. , pp. 31
    • Steiner, T.J.1    Yuen, A.W.C.2
  • 64
    • 0029651761 scopus 로고
    • Double-blind comparison of lamotrigine and carbamazepine in newly diagnosed epilepsy
    • Brodic MJ, Richens A, Yuen AWC, for UK Lamotrigine/Carbamazepine Monotherapy Trial Group. Double-blind comparison of lamotrigine and carbamazepine in newly diagnosed epilepsy. Lancet 1995;345: 476-9.
    • (1995) Lancet , vol.345 , pp. 476-479
    • Brodic, M.J.1    Richens, A.2    Yuen, A.W.C.3
  • 65
    • 0028129672 scopus 로고
    • The cost of epilepsy in the United Kingdom: An estimation based on the results of two population-based studies
    • Cockerell OC, Hart YM, Sander JWAS, Shorvon SD. The cost of epilepsy in the United Kingdom: an estimation based on the results of two population-based studies. Epilepsy Res 1994;18:249-60.
    • (1994) Epilepsy Res , vol.18 , pp. 249-260
    • Cockerell, O.C.1    Hart, Y.M.2    Sander, J.W.A.S.3    Shorvon, S.D.4
  • 66


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.