Correlations in the T-cell response to altered peptide ligands

Physica A: Statistical Mechanics and its Applications

Volumn 341, Issue 1-4, 2004, Pages 455-470

  Park, Jeong Man ^a,b   Deem, Michael W ^a  

^a RICE UNIVERSITY   (United States)

^b The Catholic University of Korea   (South Korea)

Author keywords

Altered peptide ligands; Immune system; Random energy model

Indexed keywords

ANTIGENS; CELLS; CORRELATION METHODS; DISEASES; MATHEMATICAL MODELS; MOLECULAR STRUCTURE; PROTEINS;

ALTERED PEPTIDE MODELS; HISTOCOMPATIBILITY; RANDOM ENERGY MODEL;

IMMUNOLOGY;

EID: 3342878418     PISSN: 03784371     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.physa.2004.04.127     Document Type: Article

References (26)

1. Perelson A.S., Weisbuch G. Immunology for physicists. Rev. Mod. Phys. 69:1997;1219-1267.
2. Arstila T.P., Casrouge A., Baron V., Even J., Kanellopoulos J., Kourilsky P. Direct estimate of the human. αβ T-cell receptor diversity Science. 286:1999;958-961.
3. Blattman J.N., Sourdive D.J.D., Murali-Krishna K., Ahmed R., Altman J.D. Evolution of the T-cell repertoire during primary, memory, and recall responses to viral infection. J. Immunol. 165:2000;6081-6090. (Note the non-linear expansion of the different T-cells between the naive and primary repertoires in Figure 1).
4. Sourdive D.J.D., Murali-Krishna K., Altman J.D., Zajac A.J., Whitmire J.K., Pannetier C., Kourilsky P., Evavold B., Sette A., Ahmed R. Conserved T-cell receptor repertoire in primary and memory CD8 T-cell responses to an accute viral infection. J. Exp. Med. 188:1998;71-82.
5. Lee K.H., Holdorf A.D., Dustin M.L., Chan A.C., Allen P.M., Shaw A.S. T-cell receptor signaling preceeds immunological synapse formation. Science. 295:2002;1539-1542.
6. Lee K.H., Dinnner A.R., Tu C., Campi G., Raychaudhuri S., Varma R., Sims T.N., Burack W.R., Wu H., Kanagaw O., Markiewicz M., Allen P.M., Dustin M.L., Chakraborty A.K., Shaw A.S. The immunological synapse balances T-cell receptor signaling and degradation. Science. 302:2003;1218-1222.
7. Kedl R.M., Kappler J.W., Marrack P. Epitope dominance, competition and T-cell affinity maturation. Curr. Opin. Immunol. 15:2003;120-127.
8. Sloan-Lancaster J., Allen P.M. Altered peptide ligand-induced partial T-cell activation: molecular mechanisms and role in T-cell biology. Annu. Rev. Immunol. 14:1996;1-27.
9. Garcia K.C., Degano M., Pease L.R., Huang M., Peterson P.A., Teyton L., Wilson I.A. Structural basis of plasticity in T-cell receptor recognition of a self peptide-MHC antigen. Science. 279:1998;1166-1172.
10. Derrida B. Random energy model - limit of a family of disordered models. Phys. Rev. Lett. 45:1980;79-82.
11. Derrida B., Peliti L. Evolution in a flat fitness landscape. Bull. Math. Biol. 53:1991;355-382.
12. Kauffman S., Levin S. Towards a general-theory of adaptive walks on rugged landscapes. J. Theoret. Biol. 128:1987;11-45.
13. Perelson A.S., Macken C.A. Protein evolution on partially correlated landscapes. Proc. Natl. Acad. Sci. USA. 92:1995;9657-9661.
14. Bogarad L.D., Deem M.W. A hierarchical approach to protein molecular evolution. Proc. Natl. Acad. Sci. USA. 96:1999;2591-2595.
15. Deem M.W., Lee H.-Y. Sequence space localization in the immune system response to vaccination and disease. Phys. Rev. Lett. 91:2003;068101.
16. Chandler D. Introduction to Modern Statistical Mechanics. 1987;Oxford University Press, New York.
17. M.O. Dayhoff, R.M. Schwartz, B.C. Orcutt, A model of evolutionary change in proteins, in: Atlas of Protein Sequence and Structure, Vol. 5, M.O. Dayhoff (Ed.), National Biomedical Research Foundation, Washington, 1978, pp. 345-352.
18. Kesmir C., Borghans J.A.M., de Boer R.J. Diversity of human. αβ T cell receptors Science. 288:2000;1135.
19. Schodin B.A., Tsomides T.J., Kranz D.M. Correlation between the number of T-cell receptors required for T-cell activation and TCR-ligand affinity. Immunity. 5:1996;137-146.
20. Drossel B. Biological evolution and statistical physics. Adv. Phys. 50:2001;209-295.
21. Klenerman P., Zinkernagel R.M. Original antigenic sin impairs cytotoxic T lymphocyte responses to viruses bearing variant epitopes. Nature. 394:1998;482-485.
22. Bachmann M.F., Speiser D.E., Ohashi P.S. Functional maturation of an antiviral cytotoxic T-cell response. J. Virol. 71:1997;5764-5768.
23. Singh R.A.K., Rodgers J.R., Barry M.A. The role of T-cell antagonism and original antigenic sin in genetic immunization. J. Immunol. 169:2002;6779-6786.
24. Garboczi D.N., Ghosh P., Utz U., Fan Q.R., Biddison W.E., Wiley D.C. Structure of the complex between human T-cell receptor, viral peptide and HLA-A2. Nature. 384:1996;134-141.
25. Bachmann M.F., Speiser D.E., Zakarian A., Ohashi P.S. Inhibition of TCR triggering by a spectrum of altered peptide ligands suggests the mechanism for TCR antagonism. Eur. J. Immunol. 28:1998;3110-3119.
26. Martin S., Kohler H., Weltzien H.U., Leipner C. Selective activation of CD8 T-cell effector functions by epitope variants of lymphocytic choriomeningitis virus glycoprotein. J. Immunol. 157:1996;2358-2365.