Elevated PrPC expression predisposes to increased HSV-1 pathogenicity

Antiviral Chemistry and Chemotherapy

Volumn 17, Issue 1, 2006, Pages 41-52

  Thackray, Alana M ^a   Bujdoso, Raymond ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

HSV 1; Latency; Neuron; Prion; PrP

Indexed keywords

PRION PROTEIN; VIRUS ANTIBODY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE PREDISPOSITION; EAR; HERPES SIMPLEX; HERPES SIMPLEX VIRUS 1; HISTOPATHOLOGY; INFECTION SENSITIVITY; LATENT VIRUS INFECTION; MOUSE; NONHUMAN; OPEN READING FRAME; PATHOGENICITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; VIRUS REACTIVATION; VIRUS REPLICATION;

EID: 33344472581     PISSN: 09563202     EISSN: None     Source Type: Journal    
DOI: 10.1177/095632020601700106     Document Type: Article

References (48)

1. Arthur J, Efstathiou S & Simmons A (1993) Intranuclear foci containing low abundance herpes simplex virus latency-associated transcripts visualized by non-isotopic in situ hybridization. Journal of General Virology 74:1363-1370.
2. Bendheim PE, Brown HR, Rudelli, RD, Scala LJ, Goller NL, Wen GY, Kascsak RJ, Cashman NR & Bolton DC (1992) Nearly ubiquitous tissue distribution of the scrapie agent precursor protein. Neurology 42:149-156.
3. Bratton SB, MacFarlane M, Cain, K & Cohen GM (2000) Protein complexes activate distinct caspase cascades in death receptor and stress-induced apoptosis. Experimental Cell Research 256:27-33.
4. Brown DA & London E (2000) Structure and function of sphingolipid- and cholesterol-rich membrane rafts. Journal of Biological Chemistry 275:17221-17224.
5. Brown DR, Wong BS, Hafiz F, Clive C, Haswell SJ & Jones IM (1999) Normal prion protein has an activity like that of superoxide dismutase. Biochemical Journal 344:1-5.
6. Bueler H, Fischer M, Lang Y, Bluethmann H, Lipp HP, DeArmond SJ, Prusiner SB, Aguet M & Weissmann C (1992) Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein. Nature 356:577-582.
7. Chen SH, Garber DA, Schaffer PA, Knipe DM & Coen, DM (2000) Persistent elevated expression of cytokine transcripts in ganglia latently infected with herpes simplex virus in the absence of ganglionic replication or reactivation. Virology 278:207-216.
8. Dodelet VC & Cashman NR (1998) Prion protein expression in human leukocyte differentiation. Blood 91:1556-1561.
9. Fabry Z, Raine CS & Hart MN (1994) Nervous tissue as an immune compartment: the dialect of the immune response in the CNS. Immunology Today 15:218-224.
10. Field HJ, Bell SE, Elion GB, Nash AA & Wildy P (1979) Effect of acycloguanosine treatment on acute and latent herpes simplex infections in mice. Antimicrobial Agents & Chemotherapy 15:554-561.
11. Field HJ, Tewari D, Sutton D & Thackray AM (1995) Comparison of efficacies of famciclovir and valaciclovir against herpes simplex virus type 1 in a murine immunosuppression model. Antimicrobial Agents & Chemotherapy 39:1114-1119.
12. Fischer M, Rulicke T, Raeber A, Sailer A, Moser M, Oesch B, Brandner S, Aguzzi A & Weissmann C (1996) Prion protein (PrP) with amino-proximal deletions restoring susceptibility of PrP knockout mice to scrapie. EMBO Journal 15:1255-1264.
13. Fraser N & Valyi-Nagy T (1993) Viral, neuronal, and immune factors which may influence herpes simplex virus (HSV) latency and reactivation. Microbial Pathogenesis 15:83-91.
14. Griffith JS (1967) Self-replication and scrapie. Nature 215:1043-1044.
15. Hagglund R, Munger J, Poon AP & Roizman B (2002) U(S)3 protein kinase of herpes simplex virus 1 blocks caspase 3 activation induced by the products of U(S)1.5 and U(L)13 genes and modulates expression of transduced U(S)1.5 open reading frame in a cell type-specific manner. Journal of Virology 76:743-754.
16. Henderson G, Perng GC, Nesburn AB, Wechsler SL & Jones C (2004) The latency-related gene encoded by bovine herpesvirus 1 can suppress caspase 3 and caspase 9 cleavage during productive infection. Journal of Neurovirology 10:64-70.
17. Hill TJ, Field HJ & Blyth WA (1975) Acute and recurrent infection with herpes simplex virus in the mouse: a model for studying latency and recurrent. Journal of General Virology 28:341-353.
18. Kurschner C & Morgan JI (1995) The cellular prion protein (PrP) selectively binds to Bcl-2 in the yeast two-hybrid system. Brain Research: Molecular Brain Research 30:165-168.
19. Kurschner C & Morgan JI (1996) Analysis of interaction sites in homo- and heteromeric complexes containing Bcl-2 family members and the cellular prion protein. Brain Research: Molecular Brain Research 37:249-258.
20. Leopardi R, Van Sant C & Roizman B (1997) The herpes simplex virus 1 protein kinase US3 is required for protection from apoptosis induced by the virus. Proceedings of the National Academy of Sciences USA 94:7891-7896.
21. Maggioncalda J, Mehta A, Su YH, Fraser NW & Block TM (1996) Correlation between herpes simplex virus type 1 rate of reactivation from latent infection and the number of infected neurons in trigeminal ganglia. Virology 225:72-81.
22. Mattei V, Garofalo T, Misasi R, Circella A, Manganelli V, Lucania G, Pavan A & Sorice M (2004) Prion protein is a component of the multimolecular signaling complex involved in T cell activation. FEBS Letters 560:14-18.
23. Mouillet-Richard S, Ermonval M, Chebassier C, Laplanche JL, Lehmann S, Launay JM & Kellermann O (2000) Signal transduction through prion protein. Science 289:1925-1928.
24. Muzio M, Chinnaiyan AM, Kischkel FC, O'Rourke K, Shevchenko A, Ni J, Scaffidi C, Bretz JD, Zhang M, Gentz R, Mann M, Krammer PH, Peter ME & Dixit VM (1996) FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex. Cell 85:817-827.
25. Nagata S (1997) Apoptosis by death factor. Cell 88:355-365.
26. Nash AA, Field HJ & Quartey-Papafio R (1980) Cell-mediated immunity in herpes simplex virus-infected mice: induction, characterization and antiviral effects of delayed type hypersensitivity. Journal of General Virology 48:351-357.
27. Naslavsky N, Shmeeda H, Friedlander G, Yanai A, Futerman AH, Barenholz Y & Taraboulos A (1999) Sphingolipid depletion increases formation of the scrapie prion protein in neuroblastoma cells infected with prions. Journal of Biological Chemistry 274:20763-20771.
28. Pattison IH, Clarke MC, Haig DA & Jebbett JN (1971) Brain cell cultures from mice affected with scrapie or fed with cuprizone. Research in Veterinary Science 12:478-480.
29. Pattison IH & Jebbett JN (1971a) Clinical and histological observations on cuprizone toxicity and scrapie in mice. Research in Veterinary Science 12:378-380.
30. Pattison IH & Jebbett JN (1971b) Histopathological similarities between scrapie and cuprizone toxicity in mice. Nature 230:115-117.
31. Pereira RA, Tscharke DC & Simmons A (1994) Upregulation of class I major histocompatibility complex gene expression in primary sensory neurons, satellite cells, and Schwann cells of mice in response to acute but not latent herpes simplex virus infection in vivo. Journal of Experimental Medicine 180:841-850.
32. Perng GC, Jones C, Ciacci-Zanella J, Stone M, Henderson G, Yukht A, Slanina SM, Hofman FM, Ghiasi H, Nesburn AB & Wechsler SL (2000) Virus-induced neuronal apoptosis blocked by the herpes simplex virus latency-associated transcript. Science 287:1500-1503.
33. Prusiner SB (1982) Novel proteinaceous infectious particles cause scrapie. Science 216:136-144.
34. Roizman B (1996) The Herpesviridae. In Fields Virology, pp. p2221-2226. Edited by B. N. Fields, D. M. Knipe & P. M. Howley. Philadelphia, USA: Lippincott-Raven.
35. Schild H, Mavaddat N, Litzenberger C, Ehrich EW, Davis MM, Bluestone JA, Matis L, Draper RK & Chien YH (1994) The nature of major histocompatibility complex recognition by gamma delta T cells. Cell 76:29-37.
36. Sciammas R, Johnson RM, Sperling AI, Brady W, Linsley PS, Spear PG, Fitch FW & Bluestone JA (1994) Unique antigen recognition by a herpesvirus-specific TCR-gamma delta cell. Journal of Immunology 152:5392-5397.
37. Sciammas R, Kodukula P, Tang Q, Hendricks RL & Bluestone JA (1997) T cell receptor-gamma/delta cells protect mice from herpes simplex virus type 1-induced lethal encephalitis. Journal of Experimental Medicine 185:1969-1975.
38. Simmons A & Nash AA (1987) Effect of B cell suppression on primary infection and reinfection of mice with herpes simplex virus. Journal of Infectious Diseases 155:649-654.
39. Solforosi L, Criado JR, McGavern DB, Wirz S, Sanchez-Alavez M, Sugama S, DeGiorgio LA, Volpe BT, Wiseman E, Abalos G, Masliah E, Gilden D, Oldstone MB, Conti B & Williamson RA. (2004) Cross-linking cellular prion protein triggers neuronal apoptosis in vivo. Science 303:1514-1516.
40. Thackray AM & Bujdoso R (2002) PrP(c) expression influences the establishment of herpes simplex virus type 1 latency. Journal of Virology 76:2498-2509.
41. Thackray AM & Field HJ (1996) Differential effects of famciclovir and valaciclovir on the pathogenesis of herpes simplex virus in a murine infection model including reactivation from latency. Journal of Infectious Diseases 173:291-299.
42. Thackray AM & Field HJ (1998) Famciclovir and valaciclovir differ in the prevention of herpes simplex virus type 1 latency in mice: a quantitative study. Antimicrobial Agents & Chemotherapy 42:1555-1562.
43. Thackray AM, Madec JY, Wong E, Morgan-Warren R, Brown DR, Baron T & Bujdoso R (2003) Detection of bovine spongiform encephalopathy, ovine scrapie prion-related protein (PrPSc) and normal PrPc by monoclonal antibodies raised to copper-refolded prion protein. Biochemical Journal 370:81-90.
44. Thompson RL & Sawtell NM (2000) Replication of herpes simplex virus type 1 within trigeminal ganglia is required for high frequency but not high viral genome copy number latency. Journal of Virology 74:965-974.
45. Thompson RL & Sawtell NM (2001) Herpes simplex virus type 1 latency-associated transcript gene promotes neuronal survival. Journal of Virology 75:6660-6675.
46. Vey M, Pilkuhn S, Wille H, Nixon R, DeArmond SJ, Smart EJ, Anderson RG, Taraboulos A & Prusiner SB (1996) Subcellular colocalization of the cellular and scrapie prion proteins in caveolae-like membranous domains. Proceedings of the National Academy of Sciences USA 93:14945-14949.
47. Wadsworth JD, Hill AF, Joiner S, Jackson GS, Clarke AR & Collinge J (1999) Strain-specific prion-protein conformation determined by metal ions. Nature Cell Biology 1:55-59.
48. Watanabe D, Honda T, Nishio K, Tomita Y, Sugiura Y & Nishiyama, Y. (2000) Corneal infection of herpes simplex virus type 2-induced neuronal apoptosis in the brain stem of mice with expression of tumor suppressor gene (p53) and transcription factors. Acta Neuropathologica (Berl.) 100:647-653.