Prognostic significance of vascular endothelial growth factor expression and microvessel density in carcinoma of ampulla of Vater

Hepato-Gastroenterology

Volumn 53, Issue 67, 2006, Pages 45-50

  Chen, Li ^a   Tao, Si Feng ^a   Zheng, Yi Xiong ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

Ampullary carcinoma; Immunohistochemistry; Microvessel density (MVD); Prognosis; Vascular endothelial growth factor (VEGF)

Indexed keywords

CD34 ANTIGEN; PEROXIDASE; STREPTAVIDIN; VASCULOTROPIN;

ADULT; AGED; ARTICLE; CANCER STAGING; CANCER SURGERY; CANCER SURVIVAL; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MALE; MICROVASCULATURE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; VATER PAPILLA CARCINOMA;

ADULT; AGED; AMPULLA OF VATER; CARCINOMA; COMMON BILE DUCT NEOPLASMS; FEMALE; HUMANS; MALE; MICROCIRCULATION; MIDDLE AGED; PROGNOSIS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 33344463370     PISSN: 01726390     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Folkman J: What is the evidence that tumors are angiogenesis dependent? J Natl Cancer Inst 1990; 82:4-6.
2. Ellis LM, Gall Eckhardt S: Integrating molecular oncology into clinical practice: antiangiogenic therapy. J Clin Oncol 2005; 23:937-938.
3. Carmeliet P: Angiogenesis in health and disease. Nat Med 2003; 9:653-660.
4. Ferrara N, Gerber HP, LeCouter J: The biology of VEGF and its receptors. Nat Med 2003; 9:669-676.
5. Hicklin DJ, Ellis LM: Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis. J Clin Oncol 2005; 23:1011-1027.
6. Takahashi Y, Kitadai Y, Bucana CD, Cleary KR, Ellis LM: Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer. Cancer Res 1995; 55:3964-3968.
7. Lee JC, Chow NH, Wang ST, Huang SM: Prognostic value of vascular endothelial growth factor expression in colorectal cancer patients. Eur J Cancer 2000; 36:748-753.
8. Takahashi Y, Cleary KR, Mai M, Kitadai Y, Bucana CD, Ellis LM: Significance of vessel count and vascular endothelial growth factor and its receptor (KDR) in intestinal-type gastric cancer. Clin Cancer Res 1996; 2:1679-1684.
9. Maeda K, Chung YS, Ogawa Y, Takatsuka S, Kang SM, Ogawa M, Sawada T, Sowa M: Prognostic value of vascular endothelial growth factor expression in gastric carcinoma. Cancer 1996; 77:858-863.
10. Berns EMJJ, Klijn JGM, Look MP, Grebenchtchikov N, Vossen R, Peters H, Geurts-Moespot A, Portengen H, van Staveren IL, Meijer-van Gelder ME, Bakker B, Sweep FCGJ, Foekens JA: Combined vascular endothelial growth factor and TP53 status predicts poor response to tamoxifen therapy in estrogen receptor-positive advanced breast cancer. Clin Cancer Res 2003; 9:1253-1258.
11. Manders P, Beex LV, Tjan-Heijnen VC, Geurts-Moespot J, Van Tienoven TH, Foekens JA, Sweep CG: The prognostic value of vascular endothelial growth factor in 574 node-negative breast cancer patients who did not receive adjuvant systemic therapy. Br J Cancer 2002; 87:772-778.
12. George DJ, Halabi S, Shepard TF, Vogelzang NJ, Hayes DF, Small EJ, Kantoff PW: Prognostic significance of plasma vascular endothelial growth factor levels in patients with hormone-refractory prostate cancer treated on cancer and leukemia group B 9480. Clin Cancer Res 2001; 7:1932-1936.
13. Lucchi FM, Vignati S, Mussi A, Ciardiello F, De Laurentiis M, De Placido S, Basolo F, Angeletti CA, Bevilacqua G: Angiogenesis as a prognostic indicator of survival in non-small-cell lung carcinoma: a prospective study. J Natl Cancer Inst 1997; 89:881-886.
14. Gorski DH, Leal AD, Goydos JS: Differential expression of vascular endothelial growth factor-A isoforms at different stages of melanoma progression. J Am Coll Surg 2003; 197:408-418.
15. Dvorak HF, Brown LF, Detmer M, Dvorak AM: Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability and angiogenesis. Am J Pathol 1995; 146:1029-1039.
16. Ferrara N: Role of VEGF in the regulation of angiogenesis. Kidney Int 1999; 56:794-814.
17. Obermair A, Kurz C, Czerwenka K, Thoma M, Kaider A, Wagner T, Gitsch G, Sevelda P: Microvessel density and vessel invasion in lymph-node-negative breast cancer: Effect on recurrence free survival. Int J Cancer 1995; 62:126-131.
18. Wiggins DL, Granai CO, Steinhoff MM, Calabresi P: Tumor angiogenesis as a prognostic factor in cervical carcinoma. Gynecol Oncol 1995; 56:353-356.
19. Hollingsworth HC, Kohn EC, Steinberg SM, Rothenberg ML, Merino MJ: Tumor angiogenesis in advanced stage ovarian carcinoma. Am J Pathol 1995; 147:33-41.
20. Weidner N: Intratumoral microvessel density as a prognostic factor in cancer. Am J Pathol 1995; 147:9-19.
21. Weidner N, Folkman J, Pozza F, Bevilacqua P, Allred EN, Moore DH, Meli S, Gasparini G: Tumor angiogenesis: a new significant and independent prognostic indicator in early-stage breast carcinoma. J Natl Cancer Inst 1992; 84:1875-1887.
22. Baczako K, Buchler M, Beger HG, Kirkpatrick J, Haferkamp O: Morphogenesis and possible precursor lesions of invasive carcinoma of the papilla of Vater: epithelial dysplasia and adenoma. Hum Pathol 1985; 16:305-310.
23. Hayes DH, Bolton JS, Willis GW, Bowen JC: Carcinoma of ampulla of Vater. Ann Surg 1987; 206:572-577.
24. Ikeda N, Adachi M, Taki T: Prognostic significance of angiogenesis in human pancreatic cancer. Br J Cancer 1999; 79:1553-1563.
25. Folkman J: Tumor angiogenesis: therapeutic implications. N Engl J Med 1971; 285:1182-1186.
26. Fidler IJ, Ellis LM: The implications of angiogenesis for the biology and therapy of cancer metastasis. Cell 1994; 79:185-188.
27. Detmar M, Velasco P, Richard L, Claffey KP, Streit M, Riccardi L, Skobe M, Brown LF: Expression of vascular endothelial growth factor induces an invasive phenotype in human squamous cell carcinomas. Am J Pathol 2000; 156:159-167.
28. Martin L, Holcombe C, Renshow C: Standandising the counting technique of neovascularisation in invasive breast cancer. Breast Cancer Res Treat 1996; 37:34-39.
29. Beger HG, Warshow AL, Buchler MW: The pancreas. 1st Edition. London: Blackwell Science Ltd, 1998; pp. 1287-1342.
30. Andersen HB, Baden H, Brahe NE, Burcharth F: Pancreaticoduodenectomy for periampullary adenocarcinoma. J Am Coll Surg 1994; 179:545-552.
31. Pugh CW, Ratcliffe PJ: Regulation of angiogenesis by hypoxia: role of the HIF system. Nat Med 2003; 9:677-684.
32. Harris AL: Hypoxia-a key regulatory factor in tumour growth. Nat Rev Cancer 2002; 2:38-47.