Assessment of glutamate loss from the ganglion cell layer of young DBA/2J mice with glaucoma

American Journal of Veterinary Research

Volumn 67, Issue 2, 2006, Pages 302-309

  Low, Heather C ^a   Gionfriddo, Juliet R ^a   Madl, James E ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMIC ACID; TOLONIUM CHLORIDE;

ANIMAL CELL; ANIMAL EUTHANASIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL STRUCTURE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DIGITAL IMAGING; GLAUCOMA; HISTOPATHOLOGY; IMMUNOGOLD STAINING; IMMUNOREACTIVITY; INTRAOCULAR PRESSURE ABNORMALITY; MOUSE; MOUSE STRAIN; NERVE CELL LESION; NONHUMAN; PATHOGENESIS; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RETINA DISEASE; RETINA GANGLION CELL; TISSUE FIXATION; TISSUE SECTION;

AGING; ANIMALS; GLAUCOMA; GLUTAMIC ACID; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; RETINAL GANGLION CELLS;

ANIMALIA;

EID: 33344460705     PISSN: 00029645     EISSN: None     Source Type: Journal    
DOI: 10.2460/ajvr.67.2.302     Document Type: Article

References (46)

1. Goldberg I. Relationship between intraocular pressure and preservation of visual field in glaucoma. Surv Ophthalmol 2003;48(suppl 1):S3-S7.
2. Birinci H, Danaci M, Oge I, et al. Ocular blood flow in healthy and primary open-angle glaucomatous eyes. Ophthalmologica 2002;216:434-437.
3. Cheng CY, Liu CJ, Chiou HJ, et al. Color Doppler imaging study of retrobulbar hemodynamics in chronic angle-closure glaucoma. Ophthalmology 2001;108:1445-1451.
4. Chung HS, Harris A, Evans DW, et al. Vascular aspects in the pathophysiology of glaucomatous optic neuropathy. Surv Ophthalmol 1999;43(suppl 1):S43-S50.
5. Brooks DE, Garcia GA, Dreyer EB, et al. Vitreous body glutamate concentration in dogs with glaucoma. Am J Vet Res 1997;58:864-867.
6. Dkhissi O, Chanut E, Wasowicz M, et al. Retinal TUNEL-positive cells and high glutamate levels in vitreous humor of mutant quail with a glaucoma-like disorder. Invest Ophthalmol Vis Sci 1999; 40:990-995.
7. Dreyer EB, Zurakowski D, Schumer RA, et al. Elevated glutamate levels in the vitreous body of humans and monkeys with glaucoma. Arch Ophthalmol 1996;114:299-305.
8. Kerrigan LA, Zack DJ, Quigley HA, et al. TUNEL-positive ganglion cells in human primary open-angle glaucoma. Arch Ophthalmol 1997;115:1031-1035.
9. Quigley HA, McKinnon SJ, Zack DJ, et al. Retrograde axonal transport of BDNF in retinal ganglion cells is blocked by acute IOP elevation in rats. Invest Ophthalmol Vis Sci 2000;41:3460-3466.
10. Anderson MG, Smith RS, Hawes NL, et al. Mutations in genes encoding melanosomal proteins cause pigmentary glaucoma in DBA/2J mice. Nat Genet 2002;30:81-85.
11. Chang B, Smith RS, Hawes NL, et al. Interacting loci cause severe iris atrophy and glaucoma in DBA/2J mice. Nat Genet 1999;21:405-409.
12. van de Sandt R, Boeve MH, Stades FC, et al. Abnormal ocular pigment deposition and glaucoma in the dog. Vet Ophthalmol 2003;6:273-278.
13. Miller PE. Glaucoma. In: Bonagura JD, Kirk RW, eds. Current veterinargy theraphy XII. Philadelphia: WB Saunders Co, 1995;1265-1272.
14. Gelatt KN, Brooks D. The canine glaucomas. In: Gelatt KN, ed. Veterinary ophthalmology. 3rd ed. Philadelphia: Lippincott Williams & Wilkins, 1999;701-754.
15. Kwong JM, Lam TT. N-methyl-D-aspartate (NMDA) induced apoptosis in adult rabbit retinas. Exp Eye Res 2000;71:437-444.
16. Luc DR, Newhouse JP. The toxic effects of sodium L-glutamate on the inner layers of the retina. Arch Ophthalmol 1957;58:193-201.
17. Anderson MG, Smith RS, Savinova OV, et al. Genetic modification of glaucoma associated phenotypes between AKXD-28/Ty and DBA/2J mice. BMC Genet 2001;2:1.
18. Schuettauf F, Quinto K, Naskar R, et al. Effects of anti-glaucoma medications on ganglion cell survival: the DBA/2J mouse model. Vis Res 2002;42:2333-2337.
19. Hare W, WoldeMussie E, Lai R, et al. Efficacy and safety of memantine, an NMDA-type open-channel blocker, for reduction of retinal injury associated with experimental glaucoma in rat and monkey. Surv Ophthalmol 2001;45(suppl 3):S284-S289.
20. Hare WA, WoldeMussie E, Lai RK, et al. Efficacy and safety of memantine treatment for reduction of changes associated with experimental glaucoma in monkey, I: functional measures. Invest Ophthalmol Vis Sci 2004;45:2625-2639.
21. Hare WA, WoldeMussie E, Weinreb RN, et al. Efficacy and safety of memantine treatment for reduction of changes associated with expe ental glaucoma in monkey, II: structural measures. Invest Ophthalmol Vis Sci 2004;45:2640-2651.
22. Globus MY, Busto R, Martinez E, et al. Ischemia induces release of glutamate in regions spared from histopathologic damage in the rat. Stroke 1990;21(suppl 11):III43-III46.
23. Meldrum B. Protection against ischaemic neuronal damage by drugs acting on excitatory neurotransmission. Cerebrovasc Brain Metab Rev 1990;2:27-57.
24. Martin KR, Levkovitch-Verbin H, Valenta D, et al. Retinal glutamate transporter changes in experimental glaucoma and after optic nerve transection in the rat. Invest Ophthalmol Vis Sci 2002; 43:2236-2243.
25. Naskar R, Vorwerk CK, Dreyer EB. Concurrent downregulation of a glutamate transporter and receptor in glaucoma. Invest Ophthalmol Vis Sci 2000;41:1940-1944.
26. Kitazawa Y, Yamamoto T. Glaucomatous visual field defects: their characteristics and how to detect them. Clin Neurosci 1997;4:279-283.
27. McIlnay TR, Gionfriddo JR, Dubielzig RR, et al. Evaluation of glutamate loss from damaged retinal cells of dogs with primary glaucoma. Am J Vet Res 2004;65:776-786.
28. Whiteman AL, Klauss G, Miller PE, et al. Morphologic features of degeneration and cell death in the neurosensory retina in dogs with primary angle-closure glaucoma. Am J Vet Res 2002;63:257-261.
29. John SW, Smith RS, Savinova OV, et al. Essential iris atrophy, pigment dispersion, and glaucoma in DBA/2J mice. Invest Ophthalmol Vis Sci 1998;39:951-962.
30. Schuettauf F, Rejdak R, Walski M, et al. Retinal neurodegeneration in the DBA/2J mouse - a model for ocular hypertension. Acta Neuropathol (Berl) 2004;107:352-358.
31. Dyka FM, May CA, Enz R. Metabotropic glutamate receptors are differentially regulated under elevated intraocular pressure. J Neurochem 2004;90:190-202.
32. Perlman JI, McCole SM, Pulluru P, et al. Disturbances in the distribution of neurotransmitters in the rat retina after ischemia. Curr Eye Res 1996;15:589-596.
33. Madl JE, McIlnay TR, Powell CC, et al. Depletion of taurine and glutarnate from damaged photoreceptors in the retinas of dogs with primary glaucoma. Am J Vet Res 2005;66:791-799.
34. Marc RE, Murry RF, Fisher SK, et al. Amino acid signatures in the normal cat retina. Invest Ophthalmol Vis Sci 1998;39:1685-1693.
35. Torp R, Arvin B, Le Peillet E, et al. Effect of ischaemia and reperfusion on the extra- and intracellular distribution of glutamate, glutamine, aspartate and GABA in the rat hippocampus, with a note on the effect of the sodium channel blocker BW1003C87. Exp Brain Res 1993;96:365-376.
36. Torp R, Andine P, Hagberg H, et al. Cellular and subcellular redistribution of glutamate-, glutamine- and taurine-ne immunoreactivities during forebrain ischemia: a semiquantitative electron microscopic study in rat hippocampus. Neuroscience 1991;41:433-447.
37. Madl JE, Royer SM. Glutamate in synaptic terminals is reduced by lack of glucose but not hypoxia in rat hippocampal slices. Neuroscience 1999;94:417-430.
38. Gundersen V, Fonnum F, Ottersen OP, et al. Redistribution of neuroactive amino acids in hippocampus and striatum during hypoglycemia: a quantitative immunogold study. J Cereb Blood Flow Metab 2001;21:41-51.
39. Izumi Y, Hammerman SB, Kirby CO, et al. Involvement of glutamate in ischemic neurodegeneration in isolated retina. Vis Neurosci 2003;20:97-107.
40. Napper GA, Kalloniatis M. Neurochemical changes following postmortem ischemia in the rat retina. Vis Neurosci 1999;16:1169-1180.
41. Kim IB, Kim KY, Joo CK, et al. Reaction of Muller cells after increased intraocular pressure in the rat retina. Exp Brain Res 1998;121:419-424.
42. Osborne NN, Larsen AK. Antigens associated with specific retinal cells are affected by ischaemia caused by raised intraocular pressure: effect of glutamate antagonists. Neurochem Int 1996;29:263-270.
43. Carter-Dawson L, Shen F, Harwerth RS, et al. Glutamine immunoreactivity in Muller cells of monkey eyes with experimental glaucoma. Exp Eye Res 1998;66:537-545.
44. Reichelt W, Stabel-Burow J, Pannicke T, et al. The glutathione level of retinal Muller glial cells is dependent on the high-affinity sodium-dependent uptake of glutamate. Neuroscience 1997;77:1213-1224.
45. Neufeld AH. Nitric oxide: a potential mediator of retinal ganglion cell damage in glaucoma. Surv Ophthalmol 1999;43(suppl 1):S129-S135.
46. Siu AW, Leung MC, To CH, et al. Total retinal nitric oxide production is increased in intraocular pressure-elevated rats. Exp Eye Res 2002;75:401-406.