A 36 residues insertion in the dimerization domain of the growth hormone receptor results in defective trafficking rather than impaired signaling

Journal of Endocrinology

Volumn 188, Issue 2, 2006, Pages 251-261

  Maamra, M ^a   Milward, A ^a   Esfahani, H Zarkesh ^c   Abbott, L P ^a   Metherell, L A ^b   Savage, M O ^b   Clark, A J L ^b   Ross, R J M ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^c UNIVERSITY OF ISFAHAN   (Iran)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE RECEPTOR; JANUS KINASE 2; STAT5 PROTEIN;

ARTICLE; BINDING ASSAY; CASE REPORT; CELL NUCLEUS; CELL SURFACE; CELL VACUOLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DIMERIZATION; ENZYME ACTIVITY; EXON; FAMILY STUDY; FLOW CYTOMETRY; GENE INACTIVATION; GENE INSERTION SEQUENCE; GENETIC TRANSFECTION; GROWTH HORMONE INSENSITIVITY SYNDROME; HORMONE RESISTANCE; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; MALE; MAMMAL CELL; MEMBRANE BINDING; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; RADIOASSAY; SIGNAL TRANSDUCTION; WESTERN BLOTTING; WILD TYPE;

AMINO ACIDS; BLOTTING, WESTERN; CELL MEMBRANE; CELLS, CULTURED; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; HOMOZYGOTE; HUMANS; JANUS KINASE 2; LARON SYNDROME; LUCIFERASES; MALE; PHOSPHORYLATION; POINT MUTATION; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; RECEPTORS, SOMATOTROPIN; SIGNAL TRANSDUCTION; STAT5 TRANSCRIPTION FACTOR; TRANSFECTION;

EID: 33244482820     PISSN: 00220795     EISSN: None     Source Type: Journal    
DOI: 10.1677/joe.1.06252     Document Type: Article

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