Increased phospholamban phosphorylation limits the force-frequency response in the MLP -/- mouse with heart failure

Journal of Molecular and Cellular Cardiology

Volumn 40, Issue 3, 2006, Pages 350-360

  Antoons, Gudrun ^a   Vangheluwe, Peter ^b   Volders, Paul G A ^c   Bito, Virginie ^a   Holemans, Patricia ^a   Ceci, Marcello ^e   Wuytack, Frank ^b   Caroni, Pico ^d   Mubagwa, Kanigula ^b   Sipido, Karin R ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^d FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

^e SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Frequency response; Heart failure; Phospholamban; Sarcoplasmic reticulum

Indexed keywords

CALCIUM; LIM PROTEIN; PHOSPHOLAMBAN;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CALCIUM TRANSPORT; CONGESTIVE CARDIOMYOPATHY; CONTROLLED STUDY; FREQUENCY ANALYSIS; HEART FAILURE; HEART LEFT VENTRICLE; HEART MUSCLE CELL; HOMOGENATE; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SARCOPLASMIC RETICULUM; STATISTICAL ANALYSIS; STIMULATION; TEMPERATURE; VOLTAGE CLAMP;

ANIMALS; CALCIUM; CALCIUM CHANNELS, L-TYPE; CALCIUM-BINDING PROTEINS; ELECTRIC STIMULATION; HEART DISEASES; HEART VENTRICLES; MICE; MICE, KNOCKOUT; MYOCYTES, CARDIAC; PHOSPHORYLATION; SARCOPLASMIC RETICULUM;

ANIMALIA;

EID: 33244479866     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2005.12.002     Document Type: Article

References (53)

1. L.A. Mulieri, G. Hasenfuss, B. Leavitt, P.D. Allen, and N.R. Alpert Altered myocardial force-frequency relation in human heart failure Circulation 85 1992 1743 1750
2. M. Lindner, E. Erdmann, and D.J. Beuckelmann Calcium content of the sarcoplasmic reticulum in isolated ventricular myocytes from patients with terminal heart failure J. Mol. Cell. Cardiol. 30 1998 743 749
3. V. Piacentino III, C.R. Weber, X. Chen, J. Weisser-Thomas, K.B. Margulies, and D.M. Bers Cellular basis of abnormal calcium transients of failing human ventricular myocytes Circ. Res. 92 2003 651 658
4. 2+ content in isolated failing and non-failing human myocardium Circ. Res. 85 1999 38 46
5. 2+ release from the sarcoplasmic reticulum in human ventricular myocytes from end-stage heart failure Cardiovasc. Res. 37 1998 478 488
6. G. Hasenfuss, and B. Pieske Calcium cycling in congestive heart failure J. Mol. Cell. Cardiol. 34 2002 951 969
7. S.O. Marx, S. Reiken, Y. Hisamatsu, T. Jayaraman, D. Burkhoff, and N. Rosemblit PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts Cell 101 2000 365 376
8. E. Ehler, R. Horowits, C. Zuppinger, R.L. Price, E. Perriard, and M. Leu Alterations at the intercalated disk associated with the absence of muscle LIM protein J. Cell Biol. 153 2001 763 772
9. O. Zolk, P. Caroni, and M. Bohm Decreased expression of the cardiac LIM domain protein MLP in chronic human heart failure Circulation 101 2000 2674 2677
10. A. Ecarnot-Laubriet, K. De Luca, D. Vandroux, M. Moisant, C. Bernard, and M. Assem Downregulation and nuclear relocation of MLP during the progression of right ventricular hypertrophy induced by chronic pressure overload J. Mol. Cell. Cardiol. 32 2000 2385 2395
11. R. Knoll, M. Hoshijima, H.M. Hoffman, V. Person, I. Lorenzen-Schmidt, and M.L. Bang The cardiac mechanical stretch sensor machinery involves a Z disc complex that is defective in a subset of human dilated cardiomyopathy Cell 111 2002 943 955
12. C. Geier, A. Perrot, C. Ozcelik, P. Binner, D. Counsell, and K. Hoffmann Mutations in the human muscle LIM protein gene in families with hypertrophic cardiomyopathy Circulation 107 2003 1390 1395
13. S. Arber, J.J. Hunter, J.J. Ross, M. Hongo, G. Sansig, and J. Borg MLP-deficient mice exhibit a disruption of cardiac architectural organization, dilated cardiomyopathy, and heart failure Cell 88 1997 393 403
14. G. Esposito, L.F. Santana, K. Dilly, J.D. Cruz, L. Mao, and W.J. Lederer Cellular and functional defects in a mouse model of heart failure Am. J. Physiol. 279 2000 H3101 H3112
15. S. Minamisawa, M. Hoshijima, G. Chu, C.A. Ward, K. Frank, and Y. Gu Chronic phospholamban-sarcoplasmic reticulum calcium ATPase interaction is the critical calcium cycling defect in dilated cardiomyopathy Cell 99 1999 313 322
16. H.A. Rockman, K.R. Chien, D.J. Choi, G. Iaccarino, J.J. Hunter, and J. Ross Jr. Expression of a beta-adrenergic receptor kinase 1 inhibitor prevents the development of myocardial failure in gene-targeted mice Proc. Natl. Acad. Sci. USA 95 1998 7000 7005
17. G. Esposito, L.F. Santana, K. Dilly, J.D. Cruz, L. Mao, and W.J. Lederer Cellular and functional defects in a mouse model of heart failure Am. J. Physiol. Heart Circ. Physiol. 279 2000 H3101 H3112
18. Z. Su, A. Yao, I. Zubair, K. Sugishita, M. Ritter, and F. Li Effects of deletion of muscle LIM protein on myocyte function Am. J. Physiol. Heart Circ. Physiol. 280 2001 H2665 H2673
19. i transients in mouse ventricular myocytes J. Physiol. 543 2002 889 898
20. A. Varro, N. Negretti, S.B. Hester, and D.A. Eisner An estimate of the calcium content of the sarcoplasmic reticulum in rat ventricular myocytes Pflugers Arch. 423 1993 158 160
21. P. Rodriguez, M.S. Bhogal, and J. Colyer Stoichiometric phosphorylation of cardiac ryanodine receptor on serine 2809 by calmodulin-dependent kinase II and protein kinase A J. Biol. Chem. 278 2003 38593 38600
22. M.T. Jiang, A.J. Lokuta, E.F. Farrell, M.R. Wolff, R.A. Haworth, and H.H. Valdivia Abnormal Ca2+ release, but normal ryanodine receptors, in canine and human heart failure Circ. Res. 91 2002 1015 1022
23. C.M. Schworer, L.I. Rothblum, T.J. Thekkumkara, and H.A. Singer Identification of novel isoforms of the delta subunit of Ca2+/calmodulin- dependent protein kinase II. Differential expression in rat brain and aorta J. Biol. Chem. 268 1993 14443 14449
24. 2+ ATPase enzymatic properties using mouse cardiac tissue homogenates Anal. Biochem. 269 1999 236 244
25. C.A. Ufret-Vincenty, D.J. Baro, W.J. Lederer, H.A. Rockman, L.E. Quinones, and L.F. Santana Role of sodium channel deglycosylation in the genesis of cardiac arrhythmias in heart failure J. Biol. Chem. 276 2001 28197 28203
26. D. Hagemann, M. Kuschel, T. Kuramochi, W. Zhu, H. Cheng, and R.P. Xiao Frequency-encoding Thr17 phospholamban phosphorylation is independent of Ser16 phosphorylation in cardiac myocytes J. Biol. Chem. 275 2000 22532 22536
27. W. Zhao, Y. Uehara, G. Chu, Q. Song, J. Qian, and K. Young Threonine-17 phosphorylation of phospholamban: a key determinant of frequency-dependent increase of cardiac contractility J. Mol. Cell. Cardiol. 37 2004 607 612
28. L. Li, G. Chu, E.G. Kranias, and D.M. Bers Cardiac myocyte calcium transport in phospholamban knockout mouse: relaxation and endogenous CaMKII effects Am. J. Physiol. 274 1998 H1335 H1347
29. J.W. Bassani, R.A. Bassani, and D.M. Bers Relaxation in rabbit and rat cardiac cells: species-dependent differences in cellular mechanisms J. Physiol. 476 1994 279 293
30. M.E. Diaz, A.W. Trafford, and D.A. Eisner The effects of exogenous calcium buffers on the systolic calcium transient in rat ventricular myocytes Biophys. J. 80 2001 1915 1925
31. 2+ loads only Circ. Res. 92 2003 881 887
32. A.W. Trafford, M.E. Diaz, and D.A. Eisner A novel, rapid and reversible method to measure Ca buffering and time-course of total sarcoplasmic reticulum Ca content in cardiac ventricular myocytes Pflugers Arch. 437 1999 501 503
33. E.I. Rossman, R.E. Petre, K.W. Chaudhary, V. Piacentino III, P.M. Janssen, and J.P. Gaughan Abnormal frequency-dependent responses represent the pathophysiologic signature of contractile failure in human myocardium J. Mol. Cell. Cardiol. 36 2004 33 42
34. S. Reiken, M. Gaburjakova, J. Gaburjakova, K.K. He, A. Prieto, and E. Becker Beta-adrenergic receptor blockers restore cardiac calcium release channel (ryanodine receptor) structure and function in heart failure Circulation 104 2001 2843 2848
35. S. Reiken, M. Gaburjakova, S. Guatimosim, A.M. Gomez, J. D'Armiento, and D. Burkhoff Protein kinase A phosphorylation of the cardiac calcium release channel (ryanodine receptor) in normal and failing hearts. Role of phosphatases and response to isoproterenol J. Biol. Chem. 278 2003 444 453
36. 2+ transport Circ. Res. 93 2003 487 490
37. A.R. Marks A guide for the perplexed: towards an understanding of the molecular basis of heart failure Circulation 107 2003 1456 1459
38. 2+ leak in intact ventricular myocytes from rabbits in heart failure Circ. Res. 93 2003 592 594
39. S. Currie, C.M. Loughrey, M.A. Craig, and G.L. Smith Calcium/calmodulin- dependent protein kinase IIdelta associates with the ryanodine receptor complex and regulates channel function in rabbit heart Biochem. J. 377 2004 357 366
40. 2+/calmodulin-dependent protein kinase II phosphorylation regulates the cardiac ryanodine receptor Circ. Res. 94 2004 e61 e70
41. I. Lorenzen-Schmidt, B.D. Stuyvers, H.E. Ter Keurs, M.O. Date, M. Hoshijima, and K.R. Chien Young MLP deficient mice show diastolic dysfunction before the onset of dilated cardiomyopathy J. Mol. Cell. Cardiol. 39 2005 241 250
42. 2+/calmodulin-dependent protein kinase II in cardiac hypertrophy and heart failure Cardiovasc. Res. 63 2004 476 486
43. M.E. Anderson Calmodulin kinase signaling in heart: an intriguing candidate target for therapy of myocardial dysfunction and arrhythmias Pharmacol. Ther. 106 2005 39 55
44. 2+/calmodulin- dependent protein kinase II induces hypertrophy and dilated cardiomyopathy associated with increased protein phosphatase 2A activity J. Biol. Chem. 277 2002 1261 1267
45. T. Zhang, L.S. Maier, N.D. Dalton, S. Miyamoto, J. Ross Jr., and D.M. Bers The deltaC isoform of CaMKII is activated in cardiac hypertrophy and induces dilated cardiomyopathy and heart failure Circ. Res. 92 2003 912 919
46. S.O. Marx, S. Reiken, Y. Hisamatsu, T. Jayaraman, D. Burkhoff, and N. Rosemblit PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts Cell 101 2000 365 376
47. J. Neumann, T. Eschenhagen, L.R. Jones, B. Linck, W. Schmitz, and H. Scholz Increased expression of cardiac phosphatases in patients with end-stage heart failure J. Mol. Cell. Cardiol. 29 1997 265 272
48. A.N. Carr, A.G. Schmidt, Y. Suzuki, F. del Monte, Y. Sato, and C. Lanner Type 1 phosphatase, a negative regulator of cardiac function Mol. Cell. Biol. 22 2002 4124 4135
49. 2+-handling in failing human myocardium J. Mol. Cell. Cardiol. 33 2001 1345 1353
50. P. Boknik, I. Heinroth-Hoffmann, U. Kirchhefer, J. Knapp, B. Linck, and H. Luss Enhanced protein phosphorylation in hypertensive hypertrophy Cardiovasc. Res. 51 2001 717 728
51. 2+ ATPase type 2 (SERCA 2) in cardiac sarcoplasmic reticulum from rabbits with heart failure Cardiovasc. Res. 41 1999 135 146
52. W. Luo, I.L. Grupp, J. Harrer, S. Ponniah, G. Grupp, and J.J. Duffy Targeted ablation of the phospholamban gene is associated with markedly enhanced myocardial contractility and loss of beta-agonist stimulation Circ. Res. 75 1994 401 409
53. K. Haghighi, F. Kolokathis, L. Pater, R.A. Lynch, M. Asahi, and A.O. Gramolini Human phospholamban null results in lethal dilated cardiomyopathy revealing a critical difference between mouse and human J. Clin. Invest. 111 2003 869 876