Recombinant human erythropoietin prevents ischemia-induced apoptosis and necrosis in explant cultures of the rat organ of Corti

Neuroscience Letters

Volumn 396, Issue 2, 2006, Pages 86-90

  Andreeva, Nadezhda ^b   Nyamaa, Amarjargal ^a   Haupt, Heidemarie ^a   Gross, Johann ^a   Mazurek, Birgit ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b BRAIN RESEARCH INSTITUTE   (Russian Federation)

Author keywords

Apoptosis; Growth factors; Hair cell; Ischemia; Necrosis; Rat

Indexed keywords

DNA FRAGMENT; PHALLOIDIN; PROPIDIUM IODIDE; RECOMBINANT EPIDERMAL GROWTH FACTOR; RECOMBINANT ERYTHROPOIETIN; RECOMBINANT SOMATOMEDIN C;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL LOSS; CORTI ORGAN; DRUG ACTIVITY; DRUG BINDING; DRUG EFFICACY; DRUG MECHANISM; DRUG TOLERABILITY; EXPLANT; HAIR CELL; HEARING LOSS; ISCHEMIA; NECROSIS; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; TINNITUS;

ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; EPIDERMAL GROWTH FACTOR; ERYTHROPOIETIN; HAIR CELLS; HUMANS; INSULIN-LIKE GROWTH FACTOR I; ISCHEMIA; NECROSIS; ORGAN OF CORTI; RATS; RECOMBINANT PROTEINS;

EID: 33244465215     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2005.11.013     Document Type: Article

References (34)

1. E.J. Beilharz, C.E. Williams, M. Dragunow, E.S. Sirimanne, and P.D. Gluckman Mechanisms of delayed cell death following hypoxic-ischemic injury in the immature rat: evidence for apoptosis during selective neuronal loss Brain Res. Mol. Brain Res. 29 1995 1 14
2. E. Bonfoco, D. Krainc, M. Ankarcrona, P. Nicotera, and S.A. Lipton Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-d-aspartate or nitric oxide/superoxide in cortical cell cultures Proc. Natl. Acad. Sci. U.S.A. 92 1995 7162 7166
3. M. Brines, and A. Cerami Emerging biological roles for erythropoietin in the nervous system Nat. Rev. Neurosci. 6 2005 484 494
4. P. Cayé-Thomasen, N. Wagner, B.L. Frederiksen, K. Asal, and J. Thomsen Erythropoietin and erythropoietin receptor expression in the guinea pig inner ear Hear. Res. 203 2005 21 27
5. C. Charriaut-Marlangue, I. Margaill, A. Represa, T. Popovici, M. Plotkine, and Y. Ben Ari Apoptosis and necrosis after reversible focal ischemia: an in situ DNA fragmentation analysis J. Cereb. Blood Flow Metab. 16 1996 186 194
6. A. Doetzlhofer, P.M. White, J.E. Johnson, N. Segil, and A.K. Groves In vitro growth and differentiation of mammalian sensory hair cell progenitors: a requirement for EGF and periotic mesenchyme Dev. Biol. 272 2004 432 447
7. R.M. Edge, B.N. Evans, M. Pearce, C.P. Richter, X. Hu, and P. Dallos Morphology of the unfixed cochlea Hear. Res. 124 1998 1 16
8. H. Ehrenreich, M. Hasselblatt, C. Dembowski, L. Cepek, P. Lewczuk, M. Stiefel, H.H. Rustenbeck, N. Breiter, S. Jacob, F. Knerlich, M. Bohn, W. Poser, E. Ruther, M. Kochen, O. Gefeller, C. Gleiter, T.C. Wessel, M. De Ryck, L. Itri, H. Prange, A. Cerami, M. Brines, and A.L. Siren Erythropoietin therapy for acute stroke is both safe and beneficial Mol. Med. 8 2002 495 505
9. A. Hall Rho GTPases and the actin cytoskeleton Science 279 1998 509 514
10. B.H. Hu, D. Henderson, and T.M. Nicotera F-actin cleavage in apoptotic outer hair cells in chinchilla cochleas exposed to intense noise Hear. Res. 172 2002 1 9
11. W. Jelkmann Molecular biology of erythropoietin Intern. Med. 43 2004 649 659
12. W. Jelkmann, and K. Wagner Beneficial and ominous aspects of the pleiotropic action of erythropoietin Ann. Hematol. 83 2004 673 686
13. A.A. Juknat, M.L. Kotler, A. Quaglino, N.M. Carrillo, and T. Hevor Necrotic cell death induced by delta-aminolevulinic acid in mouse astrocytes. Protective role of melatonin and other antioxidants J. Pineal Res. 35 2003 1 11
14. J.S. Kim, I. Lopez, P.L. DiPatre, F. Liu, A. Ishiyama, and R.W. Baloh Internal auditory artery infarction: clinicopathologic correlation Neurology 52 1999 40 44
15. S.A. Lipton Erythropoietin for neurologic protection and diabetic neuropathy N. Engl. J. Med. 350 2004 2516 2517
16. F. Locatelli, P. Aljama, P. Barany, B. Canaud, F. Carrera, K.U. Eckardt, W.H. Horl, I.C. Macdougal, A. Macleod, A. Wiecek, and S. Cameron Revised European best practice guidelines for the management of anaemia in patients with chronic renal failure Nephrol. Dial. Transplant. 19 Suppl. 2 2004 ii1 ii47
17. H. Lowenheim, J. Kil, K. Gultig, and H.P. Zenner Determination of hair cell degeneration and hair cell death in neomycin treated cultures of the neonatal rat cochlea Hear. Res. 128 1999 16 26
18. R. Maddala, V.N. Reddy, D.L. Epstein, and V. Rao Growth factor induced activation of Rho and Rac GTPases and actin cytoskeletal reorganization in human lens epithelial cells Mol. Vis. 9 2003 329 336
19. B. Malgrange, J.M. Rigo, P. Coucke, M. Thiry, G. Hans, L. Nguyen, T.R. Van de Water, G. Moonen, and P.P. Lefebvre Identification of factors that maintain mammalian outer hair cells in adult organ of Corti explants Hear. Res. 170 2002 48 58
20. R. Matsuoka, K. Ogawa, H. Yaoita, W. Naganuma, K. Maehara, and Y. Maruyama Characteristics of death of neonatal rat cardiomyocytes following hypoxia or hypoxia-reoxygenation: the association of apoptosis and cell membrane disintegrity Heart Vessels 16 2002 241 248
21. B. Mazurek, E. Winter, J. Fuchs, H. Haupt, and J. Gross Susceptibility of the hair cells of the newborn rat cochlea to hypoxia and ischemia Hear. Res. 182 2003 2 8
22. A. Migheli, A. Attanasio, and D. Schiffer Ultrastructural detection of DNA strand breaks in apoptotic neural cells by in situ end-labelling techniques J. Pathol. 176 1995 27 35
23. T.M. Nicotera, B.H. Hu, and D. Henderson The caspase pathway in noise-induced apoptosis of the chinchilla cochlea J. Assoc. Res. Otolaryngol. 4 2003 466 477
24. J.Y. Rao, Y.S. Jin, Q. Zheng, J. Cheng, J. Tai, and G.P. Hemstreet III Alterations of the actin polymerization status as an apoptotic morphological effector in HL-60 cells J. Cell Biochem. 75 1999 686 697
25. A.L. Siren, M. Fratelli, M. Brines, C. Goemans, S. Casagrande, P. Lewczuk, S. Keenan, C. Gleiter, C. Pasquali, A. Capobianco, T. Mennini, R. Heumann, A. Cerami, H. Ehrenreich, and P. Ghezzi Erythropoietin prevents neuronal apoptosis after cerebral ischemia and metabolic stress Proc. Natl. Acad. Sci. U.S.A. 98 2001 4044 4049
26. H.M. Sobkowicz, J.M. Loftus, and S.M. Slapnick Tissue culture of the organ of Corti Acta Otolaryngol 502 Suppl. 1993 3 36
27. H. Staecker, and T.R. Van de Water Factors controlling hair-cell regeneration/repair in the inner ear Curr. Opin. Neurobiol. 8 1998 480 487
28. M. Taniguchi, N. Hakuba, K. Koga, F. Watanabe, J. Hyodo, and K. Gyo Apoptotic hair cell death after transient cochlear ischemia in gerbils Neuroreport 13 2002 2459 2462
29. T. Tatsumi, J. Shiraishi, N. Keira, K. Akashi, A. Mano, S. Yamanaka, S. Matoba, S. Fushiki, H. Fliss, and M. Nakagawa Intracellular ATP is required for mitochondrial apoptotic pathways in isolated hypoxic rat cardiac myocytes Cardiovasc. Res. 59 2003 428 440
30. P.R. Thorne, and A.L. Nuttall Laser Doppler measurements of cochlear blood flow during loud sound exposure in the guinea pig Hear. Res. 27 1987 1 10
31. P.R. Thorne, and A.L. Nuttall Alterations in oxygenation of cochlear endolymph during loud sound exposure Acta Otolaryngol. 107 1989 71 79
32. P. Villa, P. Bigini, T. Mennini, D. Agnello, T. Laragione, A. Cagnotto, B. Viviani, M. Marinovich, A. Cerami, T.R. Coleman, M. Brines, and P. Ghezzi Erythropoietin selectively attenuates cytokine production and inflammation in cerebral ischemia by targeting neuronal apoptosis J. Exp. Med. 198 2003 971 975
33. W.P. Yang, D. Henderson, B.H. Hu, and T.M. Nicotera Quantitative analysis of apoptotic and necrotic outer hair cells after exposure to different levels of continuous noise Hear. Res. 196 2004 69 76
34. W.H. Zheng, S. Kar, and R. Quirion Insulin-like growth factor-1-induced phosphorylation of transcription factor FKHRL1 is mediated by phosphatidylinositol 3-kinase/Akt kinase and role of this pathway in insulin-like growth factor-1-induced survival of cultured hippocampal neurons Mol. Pharmacol. 62 2002 225 233