Synthesis and structure-activity relationship studies of CD4 down-modulating cyclotriazadisulfonamide (CADA) analogues

Journal of Medicinal Chemistry

Volumn 49, Issue 4, 2006, Pages 1291-1312

  Bell, Thomas W ^a   Anugu, Sreenivasa ^a   Bailey, Patrick ^a   Catalano, Vincent J ^a   Dey, Kaka ^a   Drew, Michael G B ^b   Duffy, Noah H ^a   Jin, Qi ^a   Samala, Meinrado F ^a   Sodoma, Andrej ^c   Welch, William H ^a   Schols, Dominique ^d   Vermeire, Kurt ^d  

^a UNIVERSITY OF NEVADA   (United States)

^b Department of Chemistry ^*  (United Kingdom)

^c STONY BROOK UNIVERSITY   (United States)

^d REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

9 BENZYL 3 METHYLENE 1,5 DI 4 TOLUENESULFONYL 1,5,9 TRIAZACYCLODODECANE; TOLUENESULFONAMIDE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CELL SURFACE; COMPARATIVE MOLECULAR FIELD ANALYSIS; COMPARATIVE MOLECULAR SIMILARITY INDICES ANALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG CONFORMATION; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IC 50; QUANTITATIVE STRUCTURE ACTIVITY RELATION; SOLID STATE; STEREOCHEMISTRY;

ANTI-HIV AGENTS; ANTIGENS, CD4; CELL LINE; CRYSTALLOGRAPHY, X-RAY; HETEROCYCLIC COMPOUNDS; HIV-1; HUMANS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33144467275     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0582524     Document Type: Article

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