Histopathological and behavioral improvement of murine mucopolysaccharidosis type VII by intracerebral transplantation of neural stem cells

Molecular Therapy

Volumn 13, Issue 3, 2006, Pages 548-555

  Fukuhara, Yasuyuki ^a,b   Li, Xiao Kang ^a   Kitazawa, Yusuke ^a   Inagaki, Masumi ^c   Matsuoka, Kentaro ^a   Kosuga, Motomichi ^a   Kosaki, Rika ^a,b   Shimazaki, Takuya ^b   Endo, Hitoshi ^d   Umezawa, Akihiro ^a   Okano, Hideyuki ^b   Takahashi, Takao ^b   Okuyama, Torayuki ^a,b  

^a NATIONAL CENTER FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

^b KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c NATIONAL INSTITUTE OF MENTAL HEALTH   (Japan)

^d JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

Intracerebral transplantation; Mucopolysaccharidosis type VII; Neurosphere

Indexed keywords

BETA GLUCURONIDASE;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CELL MIGRATION; CENTRAL NERVOUS SYSTEM DISEASE; CONTROLLED STUDY; CORPUS STRIATUM; DISEASE ASSOCIATION; DONOR; EMBRYO; ENZYME ACTIVITY; EPENDYMA; FETUS; FUNCTIONAL ASSESSMENT; HIPPOCAMPUS; HISTOPATHOLOGY; IN VITRO STUDY; INJECTION SITE; LATERAL BRAIN VENTRICLE; LYSOSOME STORAGE DISEASE; MOUSE; MUCOPOLYSACCHARIDOSIS TYPE 7; NEURAL STEM CELL; NEWBORN; NONHUMAN; OLFACTORY BULB; QUANTITATIVE ANALYSIS; RECIPIENT; STEM CELL TRANSPLANTATION;

ANIMALS; ANIMALS, NEWBORN; BEHAVIOR, ANIMAL; BRAIN; EMBRYONIC STEM CELLS; GENE THERAPY; GLUCURONIDASE; HEARING; LYSOSOMES; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, TRANSGENIC; MUCOPOLYSACCHARIDOSIS VII; NEURONS; PROTEIN TRANSPORT; STEM CELL TRANSPLANTATION; TELENCEPHALON;

ANIMALIA; MURINAE;

EID: 32944454488     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ymthe.2005.09.020     Document Type: Article

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